Moving Fe2+from ferritin ion channels to catalytic OH centers depends on conserved protein cage carboxylates

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 22, 2014, Pages 7925-7930

  Behera, Rabindra K ^a,c   Theil, Elizabeth C ^a,b  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Antioxidant; BioIron; Ferrihydrite; Iron traffic; Oxidoreductase enzyme activity

Indexed keywords

CARBOXYLIC ACID; DIVALENT CATION; FERRIC HYDROXIDE; FERRITIN; FERRITIN ION CHANNEL; FERROUS ION; ION CHANNEL; OXYGEN; UNCLASSIFIED DRUG; ANTIOXIDANT; FERRIC ION; HEME; HYDROXIDE; HYDROXIDE ION; IRON; METAL; MINERAL; OXIDOREDUCTASE; SULFATE;

ARTICLE; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; DISSOLUTION; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; ANIMAL; ANURA; BIOIRON; CHEMICAL MODEL; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; IRON TRAFFIC; METABOLISM; NUCLEOTIDE SEQUENCE; OXIDOREDUCTASE ENZYME ACTIVITY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

ANTIOXIDANT; BIOIRON; FERRIHYDRITE; IRON TRAFFIC; OXIDOREDUCTASE ENZYME ACTIVITY;

ANIMALS; ANTIOXIDANTS; ANURA; CATALYSIS; CONSERVED SEQUENCE; FERRIC COMPOUNDS; FERRITINS; HEME; HYDROXIDES; ION CHANNELS; IRON; METALS; MINERALS; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; OXIDOREDUCTASES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; SULFATES;

EID: 84901840195     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1318417111     Document Type: Article

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