Urinary albumin: Creatinine ratio predicts prediabetes progression to diabetes and reversal to normoglycemia: Role of associated insulin resistance, inflammatory cytokines and low vitamin D

Journal of Diabetes

Volumn 6, Issue 4, 2014, Pages 316-322

  Dutta, Deep ^a   Choudhuri, Subhadip ^a   Mondal, Samim Ali ^a   Mukherjee, Satinath ^a   Chowdhury, Subhankar ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Albumin:creatinine ratio; Diabetes; Prediabetes; Systemic inflammation; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; ALBUMIN; CREATININE; CYTOKINE; GLUCOSE; INSULIN; INTERLEUKIN 6; VITAMIN D; 25-HYDROXYVITAMIN D; AUTACOID; GLUCOSE BLOOD LEVEL;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE URINE LEVEL; DIABETES MELLITUS; DIABETIC PATIENT; DIAGNOSTIC TEST ACCURACY STUDY; DIET RESTRICTION; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INFLAMMATION; INSULIN RESISTANCE; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; MIDDLE AGED; ORAL GLUCOSE TOLERANCE TEST; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK FACTOR; SENSITIVITY AND SPECIFICITY; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; AGED; ALBUMINURIA; ANALOGS AND DERIVATIVES; ANALYSIS; BLOOD; COHORT ANALYSIS; COMPARATIVE STUDY; COMPLICATION; DIABETES MELLITUS, TYPE 2; DISEASE COURSE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; METABOLISM; PROGNOSIS; URINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALBUMINURIA; BLOOD GLUCOSE; COHORT STUDIES; CREATININE; CYTOKINES; DIABETES MELLITUS, TYPE 2; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INFLAMMATION MEDIATORS; INSULIN RESISTANCE; MALE; MIDDLE AGED; PREDIABETIC STATE; PROGNOSIS; VITAMIN D;

EID: 84901834942     PISSN: 17530393     EISSN: 17530407     Source Type: Journal    
DOI: 10.1111/1753-0407.12112     Document Type: Article

References (29)

1. Parvanova AI, Trevisan R, Iliev IP etal. Insulin resistance and microalbuminuria: A cross-sectional, case-control study of 158 patients with type 2 diabetes and different degrees of urinary albumin excretion. Diabetes. 2006; 55: 1456-1462.
2. Shin DI, Seung KB, Yoon HE etal. Microalbuminuria is independently associated with arterial stiffness and vascular inflammation but not with carotid intima-media thickness in patients with newly diagnosed type 2 diabetes or essential hypertension. J Korean Med Sci. 2013; 28: 252-260.
3. Gerstein HC, Mann JF, Yi Q etal. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA. 2001; 286: 421-426.
4. Brantsma AH, Bakker SJ, de Zeeuw D, de Jong PE, Gansevoort RT. Urinary albumin excretion as a predictor of the development of hypertension in the general population. J Am Soc Nephrol. 2006; 17: 331-335.
5. Forman JP, Brenner BM. "Hypertension" and "microalbuminuria": The bell tolls for thee. Kidney Int. 2006; 69: 22-28.
6. Knowler WC, Barrett-Connor E, Fowler SE etal. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002; 346: 393-403.
7. Yang W, Lin L, Qi J. The preventive effect of acarbose and metformin on the IGT population from becoming diabetes mellitus: A 3-year multi-centric prospective study. Chin J Endocrinol Metab. 2001; 17: 131-136.
8. Ramachandran A, Snehalatha C, Mary S, Mukesh B, Bhaskar AD, Vijay V, Indian Diabetes Prevention Programme (IDPP). The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1). Diabetologia. 2006; 49: 289-297.
9. Mykkanen L, Haffner SM, Kuusisto J, Pyorala K, Laakso M. Microalbuminuria precedes the development of NIDDM. Diabetes. 1994; 43: 552-557.
10. Brantsma AH, Bakker SJ, Hillege HL etal. Urinary albumin excretion and its relation with C-reactive protein and the metabolic syndrome in the prediction of type 2 diabetes. Diabetes Care. 2005; 28: 2525-2530.
11. Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients: The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000; 342: 145-153.
12. Lanke J, Hedner T, Niklason A etal. Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial. Lancet. 1999; 353: 611-616.
13. Friedman AN, Marrero D, Ma Y etal. Value of urinary albumin-to-creatinine ratio as a predictor of type 2 diabetes in pre-diabetic individuals. Diabetes Care. 2008; 31: 2344-2348.
14. Kumar S, Mukherjee S, Mukhopadhyay P etal. Prevalence of diabetes and impaired fasting glucose in a selected population with special reference to influence of family history and anthropometric measurements: The Kolkata Policeman Study. J Assoc Physicians India. 2008; 56: 841-844.
15. Levy JC, Matthews DR, Hermans MP. Correct homeostasis model assessment (HOMA) evaluation uses the computer program. Diabetes Care. 1998; 21: 2191-2192.
16. Katz A, Nambi SS, Mather K etal. Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000; 85: 2402-2410.
17. Knowler WC, Fowler SE, Hamman RF etal. 10-Year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet. 2009; 374: 1677-1686.
18. Islam N, Kazmi F, Chusney GD, Mattock MB, Zaini A, Pickup JC. Ethnic differences in correlates of microalbuminuria in NIDDM. The role of the acute-phase response. Diabetes Care. 1998; 21: 385-388.
19. Chowta NK, Pant P, Chowta MN. Microalbuminuria in diabetes mellitus: Association with age, sex, weight, and creatinine clearance. Indian J Nephrol. 2009; 19: 53-56.
20. Varghese A, Deepa R, Rema M, Mohan V. Prevalence of microalbuminuria in type 2 diabetes mellitus at a diabetes centre in southern India. Postgrad Med J. 2001; 77: 399-402.
21. Allawi J, Rao PV, Gilbert R etal. Microalbuminuria in non-insulin-dependent diabetes: Its prevalence in Indian compared with Europid patients. BMJ. 1988; 296: 462-464.
22. Skaaby T, Husemoen LL, Pisinger C etal. Vitamin D status and 5-year changes in urine albumin creatinine ratio and parathyroid hormone in a general population. Endocrine. 2013. doi:10.1007/s12020-013-9887-0.
23. Li YC, Kong J, Wei M, Chen ZF, Liu SQ, Cao LP. 1, 25-Dihydroxy vitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest. 2002; 110: 229-238.
24. Tan X, Li Y, Liu Y. Therapeutic role and potential mechanisms of active vitamin D in renal interstitial fibrosis. J Steroid Biochem Mol Biol. 2007; 103: 491-496.
25. Schwarz U, Amann K, Orth SR, Simonaviciene A, Wessels S, Ritz E. Effect of 1, 25 (OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats. Kidney Int. 1998; 53: 1696-1705.
26. Zhang Z, Zhang Y, Ning G, Deb DK, Kong J, Li YC. Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase. Proc Natl Acad Sci U S A. 2008; 105: 15896-15901.
27. Takiishi T, Gysemans C, Bouillon R, Mathieu C. Vitamin D and diabetes. Endocrinol Metab Clin North Am. 2010; 39: 419-446.
28. LeRoith D. Beta-cell dysfunction and insulin resistance in type 2 diabetes: Role of metabolic and genetic abnormalities. Am J Med. 2002; 113 (Suppl. 6A): S3-S11.
29. Manna P, Jain SK. Vitamin D up-regulates glucose transporter 4 (GLUT4) translocation and glucose utilization mediated by cystathionine-γ-lyase (CSE) activation and H2S formation in 3T3L1 adipocytes. J Biol Chem. 2012; 287: 42324-42332.