메뉴 건너뛰기




Volumn 32, Issue 3, 2014, Pages 390-394

Dose reduction of tocilizumab in rheumatoid arthritis patients with low disease activity

Author keywords

Dose response relationship; Rheumatoid arthritis; Tocilizumab

Indexed keywords

TOCILIZUMAB;

EID: 84901823265     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (31)

References (17)
  • 1
    • 79953680176 scopus 로고    scopus 로고
    • Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year
    • KREMER JM, BLANCO R, BRZOSKO M et al.: Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with inadequate responses to methotrexate: results from the double-blind treatment phase of a randomized placebo-controlled trial of tocilizumab safety and prevention of structural joint damage at one year. Arthritis Rheum 2011; 63: 609-21.
    • (2011) Arthritis Rheum , vol.63 , pp. 609-621
    • Kremer, J.M.1    Blanco, R.2    Brzosko, M.3
  • 2
    • 52149099504 scopus 로고    scopus 로고
    • IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial
    • EMERY P, KEYSTONE E, TONY HP et al.: IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial. Ann Rheum Dis 2008; 67: 1516-23.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1516-1523
    • Emery, P.1    Keystone, E.2    Tony, H.P.3
  • 3
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
    • SMOLEN JS, BEAULIEU A, RUBBERT-ROTH A et al.: Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet 2008; 371: 987-97.
    • (2008) Lancet , vol.371 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3
  • 4
    • 33749363027 scopus 로고    scopus 로고
    • Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
    • MAINI RN, TAYLOR PC, SZECHINSKI J et al.: Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum 2006; 54: 2817-29.
    • (2006) Arthritis Rheum , vol.54 , pp. 2817-2829
    • Maini, R.N.1    Taylor, P.C.2    Szechinski, J.3
  • 5
    • 34447300492 scopus 로고    scopus 로고
    • Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
    • NISHIMOTO N, HASHIMOTO J, MIYASAKA N et al.: Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis 2007; 66: 1162-7.
    • (2007) Ann Rheum Dis , vol.66 , pp. 1162-1167
    • Nishimoto, N.1    Hashimoto, J.2    Miyasaka, N.3
  • 6
    • 60149105639 scopus 로고    scopus 로고
    • Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
    • NISHIMOTO N, MIYASAKA N, YAMAMOTO K et al.: Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy. Mod Rheumatol 2009; 19: 12-9.
    • (2009) Mod Rheumatol , vol.19 , pp. 12-19
    • Nishimoto, N.1    Miyasaka, N.2    Yamamoto, K.3
  • 7
    • 84901827060 scopus 로고    scopus 로고
    • EuropeEan MeEdicineEs AageEncy: RoActemra; product information (last updated 31-01-2013)
    • EuropeEan MeEdicineEs AageEncy: RoActemra; product information (last updated 31-01-2013) http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/ human/000955/WC500054890.pdf. 2013.
    • (2013)
  • 8
    • 84901848889 scopus 로고    scopus 로고
    • Uu.Ss.Aa Food and Ddrug AadmMinistration: Highlights of prescribing information
    • Uu.Ss.Aa Food and Ddrug AadmMinistration: Highlights of prescribing information. 2013.
    • (2013)
  • 9
    • 84874403935 scopus 로고    scopus 로고
    • Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement
    • SCHOELS MM, van deer HEIJDE D, BREEDVELD FC et al.: Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement. Ann Rheum Dis 2013; 72: 583-9.
    • (2013) Ann Rheum Dis , vol.72 , pp. 583-589
    • Schoels, M.M.1    van deer Heijde, D.2    Breedveld, F.C.3
  • 10
    • 79952013541 scopus 로고    scopus 로고
    • Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials
    • CAMPBELL L, CHEN C, BHAGAT SS, PARKER RA, ÖSTÖR AJK: Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials. Rheumatology 2011; 50: 552-62.
    • (2011) Rheumatology , vol.50 , pp. 552-562
    • Campbell, L.1    Chen, C.2    Bhagat, S.S.3    Parker, R.A.4    ÖStör, A.J.K.5
  • 11
    • 84867398615 scopus 로고    scopus 로고
    • Down-titration and discontinuation of infliximab in rheumatoid arthritis patients with stable low disease activity and stable treatment: an observational cohort study
    • van deEr MAAS A, KIEVIT W, van deen BEMT BJ, van deEn HOOGEN FHJ, van RIEL PL, deEn BROEDER AA: Down-titration and discontinuation of infliximab in rheumatoid arthritis patients with stable low disease activity and stable treatment: an observational cohort study. Ann Rheum Dis 2012; 71: 1849-54.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1849-1854
    • van deer Maas, A.1    Kievit, W.2    van deen Bemt, B.J.3    van deen Hoogen, F.H.J.4    van Riel, P.L.5    deen Broeder, A.A.6
  • 12
    • 84874983369 scopus 로고    scopus 로고
    • Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a radnomised controlled trial
    • SMOLEN JS, NASH P, DUREZ P et al.: Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a radnomised controlled trial. Lancet 2013; 381: 918-29.
    • (2013) Lancet , vol.381 , pp. 918-929
    • Smolen, J.S.1    Nash, P.2    Durez, P.3
  • 13
  • 14
    • 84885772627 scopus 로고    scopus 로고
    • Discontinuation of biologics in patients with rheumatoid arthritis
    • TANAKA Y, HIRATA S, SALEEM B, EMERY P: Discontinuation of biologics in patients with rheumatoid arthritis. Clin Exp Rheumatol 2013; 31 (Suppl. 78): S22-S27.
    • (2013) Clin Exp Rheumatol , vol.31 , Issue.SUPPL. 78
    • Tanaka, Y.1    Hirata, S.2    Saleem, B.3    Emery, P.4
  • 15
    • 84897569032 scopus 로고    scopus 로고
    • Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) monotherapy (DREAM STUDY)
    • NISHIMOTO N AMANO K, HIRABAYASHI Y et al.: Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) monotherapy (DREAM STUDY). Mod Rheumatol 2014; 24: 17-25.
    • (2014) Mod Rheumatol , vol.24 , pp. 17-25
    • Nishimoto, N.1    Amano, K.2    Hirabayashi, Y.3
  • 16
    • 84874426304 scopus 로고    scopus 로고
    • Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions
    • SMOLEN JS, SCHOELS MM, NISHIMOTO N et al.: Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions. Ann Rheum Dis 2013; 72: 482-92.
    • (2013) Ann Rheum Dis , vol.72 , pp. 482-492
    • Smolen, J.S.1    Schoels, M.M.2    Nishimoto, N.3
  • 17
    • 1842505633 scopus 로고    scopus 로고
    • Dose escalation of infliximab in clinical practice: improvements seen may be explained by a regression-like effect
    • van VOLLENHOVEN RF, BRANNEMARK S, KLARESKOG L: Dose escalation of infliximab in clinical practice: improvements seen may be explained by a regression-like effect. Ann Rheum Dis 2004; 63: 426-30.
    • (2004) Ann Rheum Dis , vol.63 , pp. 426-430
    • van Vollenhoven, R.F.1    Brannemark, S.2    Klareskog, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.