Role of inter-species recombination of the ftsI gene in the dissemination of altered penicillin-binding-protein-3-mediated resistance in Haemophilus influenzae and Haemophilus haemolyticus

Journal of Antimicrobial Chemotherapy

Volumn 69, Issue 6, 2014, Pages 1501-1509

  Witherden, Elizabeth A ^a   Bajanca Lavado, Maria Paula ^b   Tristram, Stephen G ^a   Nunes, Alexandra ^b  

^a UNIVERSITY OF TASMANIA   (Australia)

^b NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

Author keywords

BLNAR; Horizontal gene transfer; Mosaic genes; lactam resistance

Indexed keywords

PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 3; PENICILLINASE; PROTEIN FTSI; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE SEQUENCE; GENE STRUCTURE; GENETIC RECOMBINATION; HAEMOPHILUS; HAEMOPHILUS INFLUENZAE; HORIZONTAL GENE TRANSFER; MOSAICISM; NONHUMAN; PHYLOGENY; DRUG EFFECTS; GENETICS; HAEMOPHILUS INFECTION; HUMAN; MICROBIOLOGY; PENICILLIN RESISTANCE;

HAEMOPHILUS; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; PENICILLIN RESISTANCE; PENICILLIN-BINDING PROTEINS; RECOMBINATION, GENETIC;

EID: 84901812211     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku022     Document Type: Article

References (34)

1. Zapun A, Contreras-Martel C, Vernet T. Penicillin-binding proteins and β-lactam resistance. FEMS Microbiol Rev 2008; 32: 361-85.
2. Tristram S, Jacobs MR, Appelbaum PC. Antimicrobial resistance in Haemophilus influenzae. Clin Microbiol Rev 2007; 20: 368-89.
3. Ubukata K, Shibasaki Y, Yamamoto K et al. Association of amino acid substitutions in penicillin-binding protein 3 with β-lactam resistance in β-lactamase-negative ampicillin-resistant Haemophilus influenzae. Antimicrob Agents Chemother 2001; 45: 1693-9.
4. Doern GV, Brueggemann AB, Pierce G et al. Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of β-lactamase-positive strains resistant to amoxicillin-clavulanate: results of a national multicenter surveillance study. Antimicrob Agents Chemother 1997; 41: 292-7.
5. Karlowsky JA, Critchley IA, Blosser-Middleton RS et al. Antimicrobial surveillance of Haemophilus influenzae in the United States during 2000-2001 leads to detection of clonal dissemination of a β-lactamasenegative and ampicillin-resistant strain. J Clin Microbiol 2002; 40: 1063-6.
6. Hasegawa K, Yamamoto K, Chiba N et al. Diversity of ampicillinresistance genes in Haemophilus influenzae in Japan and the United States. Microb Drug Resist 2003; 9: 39-46.
7. Fluit AC, Florijn A, Verhoef J et al. Susceptibility of European β-lactamase-positive and-negative Haemophilus influenzae isolates from the periods 1997/1998 and 2002/2003. J Antimicrob Chemother 2005; 56: 133-8.
8. Watanabe H, Hoshino K, Sugita R et al. Possible high rate of transmission of nontypeable Haemophilus influenzae, including β-lactamase-negative ampicillin-resistant strains, between children and their parents. J Clin Microbiol 2004; 42: 362-5.
9. Hotomi M, Fujihara K, Billal DS et al. Genetic characteristics and clonal dissemination of β-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. Antimicrob Agents Chemother 2007; 51: 3969-76.
10. Kubota T, Higa F, Kusano N et al. Genetic analyses of β-lactamase negative ampicillin-resistant strains of Haemophilus influenzae isolated in Okinawa, Japan. Jpn J Infect Dis 2006; 59: 36-41.
11. Hasegawa K, Kobayashi R, Takada E et al. High prevalence of type b β-lactamase-non-producing ampicillin-resistant Haemophilus influenzae in meningitis: the situation in Japan where Hib vaccine has not been introduced. J Antimicrob Chemother 2006; 57: 1077-82.
12. Kishii K, Chiba N, Morozumi M et al. Diverse mutations in the ftsI gene in ampicillin-resistant Haemophilus influenzae isolates from pediatric patients with acute otitis media. J Infect Chemother 2010; 16: 87-93.
13. Kim IS, Ki CS, Kim S et al. Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. Antimicrob Agents Chemother 2007; 51: 453-60.
14. Witherden EA, Tristram SG. Prevalence and mechanisms of β-lactam resistance in Haemophilus haemolyticus. J Antimicrob Chemother 2013; 68: 1049-53.
15. Barbosa AR, Giufre M, Cerquetti M et al. Polymorphism in ftsI gene and β-lactam susceptibility in Portuguese Haemophilus influenzae strains: clonal dissemination of β-lactamase-positive isolates with decreased susceptibility to amoxicillin/clavulanic acid. J Antimicrob Chemother 2011; 66: 788-96.
16. Bae S, Lee J, Kim E et al. Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. Antimicrob Agents Chemother 2010; 54: 65-71.
17. Skaare D, Allum AG, Anthonisen IL et al. Mutant ftsI genes in the emergence of penicillin-binding protein-mediated β-lactam resistance in Haemophilus influenzae in Norway. Clin Microbiol Infect 2010; 16: 1117-24.
18. Park C, Kim KH, Shin NY et al. Genetic diversity of the ftsI gene in β-lactamase-nonproducing ampicillin-resistant and β-lactamaseproducing amoxicillin-clavulanic acid-resistant nasopharyngeal Haemophilus influenzae strains isolated from children in South Korea. Microb Drug Resist 2013; 19: 224-30.
19. Murphy TF, Brauer AL, Sethi S et al. Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae. J Infect Dis 2007; 195: 81-9.
20. McCrea KW, Xie J, LaCross N et al. Relationships of nontypeable Haemophilus influenzae strains to hemolytic and nonhemolytic Haemophilus haemolyticus strains. J Clin Microbiol 2008; 46: 406-16.
21. Sanbongi Y, Suzuki T, Osaki Y et al. Molecular evolution of β-lactam-resistant Haemophilus influenzae: 9-year surveillance of penicillin-binding protein 3 mutations in isolates from Japan. Antimicrob Agents Chemother 2006; 50: 2487-92.
22. Takahata S, Ida T, Senju N et al. Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. Antimicrob Agents Chemother 2007; 51: 1589-95.
23. Wiertsema SP, Kirkham LA, Corscadden KJ et al. Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule. Vaccine 2011; 29: 5163-70.
24. Gomes JP, Bruno WJ, Nunes A et al. Evolution of Chlamydia trachomatis diversity occurs by widespread interstrain recombination involving hotspots. Genome Res 2007; 17: 50-60.
25. Saitou N, Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 1987; 4: 406-25.
26. Kimura M. A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 1980; 16: 111-20.
27. Nei MaK S. Molecular Evolution and Phylogenetics. New York: Oxford University Press, 2000.
28. Chen I, Dubnau D. DNA uptake during bacterial transformation. Nat Rev Microbiol 2004; 2: 241-9.
29. Lole KS, Bollinger RC, Paranjape RS et al. Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 1999; 73: 152-60.
30. Salminen MO, Carr JK, Burke DS et al. Identification of breakpoints in intergenotypic recombinants of HIV type 1 by bootscanning. AIDS Res Hum Retrov 1995; 11: 1423-5.
31. Robertson DL, Hahn BH, Sharp PM. Recombination in AIDS viruses. J Mol Evol 1995; 40: 249-59.
32. Hakenbeck R, Balmelle N, Weber B et al. Mosaic genes and mosaic chromosomes: intra-and interspecies genomic variation of Streptococcus pneumoniae. Infect Immun 2001; 69: 2477-86.
33. Hakenbeck R. Mosaic genes and their role in penicillin-resistant Streptococcus pneumoniae. Electrophoresis 1998; 19: 597-601.
34. Sibold C, Wang J, Henrichsen J et al. Genetic relationships of penicillin-susceptible and-resistant Streptococcus pneumoniae strains isolated on different continents. Infect Immun 1992; 60: 4119-26.