메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages 21-30

Choice of fluids in severe septic patients - a cost-effectiveness analysis informed by recent clinical trials

Author keywords

Clinical trials; Colloids; Costs; Decision analysis; Fluid therapies; Sepsis

Indexed keywords

ALBUMIN; HETASTARCH; INFUSION FLUID; ALBUMINOID; CRYSTALLOID; HETASTARCH DERIVATIVE; ISOTONIC SOLUTION;

EID: 84901806984     PISSN: 15748871     EISSN: 18761038     Source Type: Journal    
DOI: 10.2174/1574887108666131213120816     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 84873339299 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2012
    • Dellinger RP, Levy M, Rhodes A, Annane D, Gerlach H, Opal S, et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013; 41(1): 580-637.
    • (2013) Crit Care Med , vol.41 , Issue.1 , pp. 580-637
    • Dellinger, R.P.1    Levy, M.2    Rhodes, A.3    Annane, D.4    Gerlach, H.5    Opal, S.6
  • 2
    • 84856241056 scopus 로고    scopus 로고
    • A critique of fluid bolus resuscitation in severe sepsis
    • Hilton A, Bellomo R. A critique of fluid bolus resuscitation in severe sepsis. Crit Care. 2012; 16(1): 302.
    • (2012) Crit Care , vol.16 , Issue.1 , pp. 302
    • Hilton, A.1    Bellomo, R.2
  • 3
    • 85077805587 scopus 로고    scopus 로고
    • National Institutes of Health [Internet]. 2013 [cited, May 21]. Available from
    • National Institutes of Health. Ongoing clinical trials on fluids in sepsis [Internet]. 2013 [cited 2013 May 21]. Available from: http://www.clinicaltrials.gov/ct2/results?term=fluids+AND+sepsis&Search=Search
    • (2013) Ongoing clinical trials on fluids in sepsis
  • 4
    • 77957920028 scopus 로고    scopus 로고
    • Resuscitation fluid use in critically ill adults: An international crosssectional study in 391 intensive care units
    • Finfer S, Liu B, Taylor C, Bellomo R, Billot L, Cook D, et al. Resuscitation fluid use in critically ill adults: an international crosssectional study in 391 intensive care units. Crit Care. 2010; 14: R185.
    • (2010) Crit Care , vol.14
    • Finfer, S.1    Liu, B.2    Taylor, C.3    Bellomo, R.4    Billot, L.5    Cook, D.6
  • 5
    • 82955194690 scopus 로고    scopus 로고
    • Type of fluid in severe sepsis and septic shock
    • Vincent J, Gottin L. Type of fluid in severe sepsis and septic shock. Minerva Anestesiol. 2011; 77: 1190-6.
    • (2011) Minerva Anestesiol , vol.77 , pp. 1190-1196
    • Vincent, J.1    Gottin, L.2
  • 6
    • 0005947519 scopus 로고    scopus 로고
    • Distribution of normal saline and 5% albumin infusions in septic patients
    • Ernest D, Belzberg AS, Dodek PM. Distribution of normal saline and 5% albumin infusions in septic patients. Critical care medicine. 1999; 27(1): 46.
    • (1999) Critical Care Medicine , vol.27 , Issue.1 , pp. 46
    • Ernest, D.1    Belzberg, A.S.2    Dodek, P.M.3
  • 7
  • 8
    • 78751646535 scopus 로고    scopus 로고
    • The SAFE Study Investigators. Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis
    • The SAFE Study Investigators. Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis. Intensive Care Medicine. 2010; 37(1): 86-96.
    • (2010) Intensive Care Medicine , vol.37 , Issue.1 , pp. 86-96
  • 9
    • 79251544293 scopus 로고    scopus 로고
    • The role of albumin as a resuscitation fluid for patients with sepsis: A systematic review and meta-analysis*
    • Delaney AP, Dan A, McCaffrey J, Finfer S. The role of albumin as a resuscitation fluid for patients with sepsis: A systematic review and meta-analysis*. Crit Care Med. 2011; 39(2): 386-91.
    • (2011) Crit Care Med , vol.39 , Issue.2 , pp. 386-391
    • Delaney, A.P.1    Dan, A.2    McCaffrey, J.3    Finfer, S.4
  • 10
    • 84881240857 scopus 로고    scopus 로고
    • Efficacy and Tolerance of Hyperoncotioc albumin Administration in Septic patients: The EARSS Study
    • Charpentier J, Mira J. Efficacy and Tolerance of Hyperoncotioc albumin Administration in Septic patients: The EARSS Study. Intensive Care Med. 2011; 37(Supplement 1): S115 (0438).
    • (2011) Intensive Care Med , vol.37 , Issue.SUPPL. 1
    • Charpentier, J.1    Mira, J.2
  • 11
    • 85077804159 scopus 로고    scopus 로고
    • Albumin in septic shock: The ALBIOS study
    • cited 2013 Jun 19]. Available from
    • Gattinoni L. Albumin in septic shock: The ALBIOS study. Lisbon; 2012 [cited 2013 Jun 19]. Available from: http://www.albuminppta.com/-sepsis-literature-database/304-albumin-administrationimproves-survival-in-severe-sepsis-and-septic-shock-the-albiosstudy-
    • (2012) Lisbon
    • Gattinoni, L.1
  • 12
    • 84866455425 scopus 로고    scopus 로고
    • The Precise RCT: Evolution of an Early Septic Shock Fluid Resuscitation Trial
    • cited 2012 Jun 27]; Available from
    • McIntyre L, Fergusson DA, Rowe B, Cook DJ, Arabi Y, Bagshaw SM, et al. The Precise RCT: Evolution of an Early Septic Shock Fluid Resuscitation Trial. Transfusion Medicine Reviews [Internet]. 2012 [cited 2012 Jun 27]; Available from: http://www.sciencedirect.com/science/article/pii/S0887796311001209
    • (2012) Transfusion Medicine Reviews [Internet
    • McIntyre, L.1    Fergusson, D.A.2    Rowe, B.3    Cook, D.J.4    Arabi, Y.5    Bagshaw, S.M.6
  • 13
    • 85077804615 scopus 로고    scopus 로고
    • A Critical Look at Colloids in the Intensive Care Unit
    • cited 2012 Jun 27]. Available from
    • Ensor C. A Critical Look at Colloids in the Intensive Care Unit. Society of Critical Care Medicine: Clinical Pharmacy and Pharmacology; 2010 [cited 2012 Jun 27]. Available from: http://www.sccm.org/SiteCollectionDocuments/CPP%20Newsletter%20April%202010.pdf
    • (2010) Society of Critical Care Medicine: Clinical Pharmacy and Pharmacology
    • Ensor, C.1
  • 15
    • 77649130119 scopus 로고    scopus 로고
    • Renal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: Systematic review and meta-analysis of randomized trials
    • Zarychanski R, Turgeon AF, Fergusson DA, Cook DJ, Hébert P, Bagshaw SM, et al. Renal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: systematic review and meta-analysis of randomized trials. Open Med. 2009; 3(4): e196.
    • (2009) Open Med , vol.3 , Issue.4
    • Zarychanski, R.1    Turgeon, A.F.2    Fergusson, D.A.3    Cook, D.J.4    Hébert, P.5    Bagshaw, S.M.6
  • 16
    • 70249124914 scopus 로고    scopus 로고
    • Hydroxyethyl starch (HES) versus other fluid therapies: Effects on kidney function
    • Dart AB, editors. Cochrane Database of Syst Rev [Internet], Jan 20 [cited 2012 Jun 27, Available from
    • Dart AB, Mutter TC, Ruth CA, Taback SP. Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function. The Cochrane Collaboration, Dart AB, editors. Cochrane Database of Syst Rev [Internet]. 2010 Jan 20 [cited 2012 Jun 27]; Available from: http: //doi.wiley.com/10.1002/14651858.CD007594.pub2
    • (2010) The Cochrane Collaboration
    • Dart, A.B.1    Mutter, T.C.2    Ruth, C.A.3    Taback, S.P.4
  • 17
    • 34548294721 scopus 로고    scopus 로고
    • Implementation of early goal-directed therapy for severe sepsis and septic shock: A decision analysis
    • Huang DT, Clermont G, Dremsizov TT, Angus DC. Implementation of early goal-directed therapy for severe sepsis and septic shock: A decision analysis. Critical Care Medicine. 2007; 35(9): 2090-100.
    • (2007) Critical Care Medicine , vol.35 , Issue.9 , pp. 2090-2100
    • Huang, D.T.1    Clermont, G.2    Dremsizov, T.T.3    Angus, D.C.4
  • 18
    • 84888091948 scopus 로고    scopus 로고
    • Relative survival benefit and morbidity with fluids in severe sepsis - a network metaanalysis of alternative therapies
    • Bansal M, Farrugia A, Balboni S, Martin G. Relative survival benefit and morbidity with fluids in severe sepsis - a network metaanalysis of alternative therapies. Curr Drug Saf. 2013; 8(4): 236-45.
    • (2013) Curr Drug Saf , vol.8 , Issue.4 , pp. 236-245
    • Bansal, M.1    Farrugia, A.2    Balboni, S.3    Martin, G.4
  • 19
    • 84887071739 scopus 로고    scopus 로고
    • Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: The cristal randomized trial
    • Annane D, Siami S, Jaber S, et al. Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: The cristal randomized trial. JAMA. 2013; 310(17): 1809-17.
    • (2013) JAMA , vol.310 , Issue.17 , pp. 1809-1817
    • Annane, D.1    Siami, S.2    Jaber, S.3
  • 20
    • 85077805445 scopus 로고    scopus 로고
    • Relative survival benefit and morbidity with fluids in severe sepsis - A network metaanalysis of alternative therapies
    • press
    • Bansal M, Farrugia A, Balboni S, Martin G. Relative survival benefit and morbidity with fluids in severe sepsis - A network metaanalysis of alternative therapies. Current Drug Safety (in press).
    • Current Drug Safety
    • Bansal, M.1    Farrugia, A.2    Balboni, S.3    Martin, G.4
  • 21
    • 65549092898 scopus 로고    scopus 로고
    • Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury
    • Vesconi S, Cruz DN, Fumagalli R, Kindgen-Milles D, Monti G, Marinho A, et al. Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury. Crit Care. 2009; 13(2): R57.
    • (2009) Crit Care , vol.13 , Issue.2
    • Vesconi, S.1    Cruz, D.N.2    Fumagalli, R.3    Kindgen-Milles, D.4    Monti, G.5    Marinho, A.6
  • 22
    • 85077804897 scopus 로고    scopus 로고
    • HCUP Nationwide Inpatient Sample (NIS)
    • Healthcare Cost and Utilization Project (HCUP, Internet, Rockville, MD, Available from
    • Healthcare Cost and Utilization Project (HCUP). HCUP Nationwide Inpatient Sample (NIS) [Internet]. Rockville, MD.: Agency for Healthcare Research and Quality; 2010. Available from: http: //hcupnet.ahrq.gov/
    • (2010) Agency For Healthcare Research and Quality
  • 23
    • 0020357091 scopus 로고
    • A Convenient Approximation of Life Expectancy (The "DEALE") II. Use in Medical Decision-Making
    • Beck J, Pauker S, Gottlieb J, Klein K, Kassirer J. A Convenient Approximation of Life Expectancy (The "DEALE") II. Use in Medical Decision-Making. The American Journal of Medicine. 1982; 73: 889-97.
    • (1982) The American Journal of Medicine , vol.73 , pp. 889-897
    • Beck, J.1    Pauker, S.2    Gottlieb, J.3    Klein, K.4    Kassirer, J.5
  • 24
    • 84870479012 scopus 로고    scopus 로고
    • The use of cost per life year gained as a measurement of cost-effectiveness in Spain: A systematic review of recent publications
    • Rodríguez Barrios JM, Pérez Alcántara F, Crespo Palomo C, González García P, Antón De Las Heras E, Brosa Riestra M. The use of cost per life year gained as a measurement of cost-effectiveness in Spain: a systematic review of recent publications. Eur J Health Econ. 2012; 13(6): 723-40.
    • (2012) Eur J Health Econ , vol.13 , Issue.6 , pp. 723-740
    • Rodríguez, B.J.M.1    Pérez, A.F.2    Crespo, P.C.3    González, G.P.4    de las Heras, A.E.5    Brosa, R.M.6
  • 27
    • 20944442517 scopus 로고    scopus 로고
    • Epidemiology and economic evaluation of severe sepsis in France: Age, severity, infection site, and place of acquisition (community, hospital, or intensive care unit) as determinants of workload and cost
    • Adrie C, Alberti C, Chaix-Couturier C, Azoulay É, de Lassence A, Cohen Y, et al. Epidemiology and economic evaluation of severe sepsis in France: age, severity, infection site, and place of acquisition (community, hospital, or intensive care unit) as determinants of workload and cost. Journal of Critical Care. 2005; 20(1): 46-58.
    • (2005) Journal of Critical Care , vol.20 , Issue.1 , pp. 46-58
    • Adrie, C.1    Alberti, C.2    Chaix-Couturier, C.3    Azoulay, É.4    de Lassence, A.5    Cohen, Y.6
  • 28
    • 84901809401 scopus 로고    scopus 로고
    • 6S Trial Group and the Scandinavian Critical Care Trials Group. Hydroxyethyl Starch 130/0.4 versus Ringer's Acetate in Severe Sepsis
    • Perner A, 6S Trial Group and the Scandinavian Critical Care Trials Group. Hydroxyethyl Starch 130/0.4 versus Ringer's Acetate in Severe Sepsis. N Engl J Med. 2012; 1-11.
    • (2012) N Engl J Med , pp. 1-11
    • Perner, A.1
  • 29
    • 79957655346 scopus 로고    scopus 로고
    • Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: A prospective sequential comparison
    • Bayer O, Reinhart K, Sakr Y, Kabisch B, Kohl M, Riedemann NC, et al. Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: A prospective sequential comparison. Critical Care Medicine. 2011; 39(6): 1335-42.
    • (2011) Critical Care Medicine , vol.39 , Issue.6 , pp. 1335-1342
    • Bayer, O.1    Reinhart, K.2    Sakr, Y.3    Kabisch, B.4    Kohl, M.5    Riedemann, N.C.6
  • 30
    • 78649437154 scopus 로고    scopus 로고
    • Continuous Renal replacement Therapy in Patients with Systemic Sepsis
    • Moemen E. Continuous Renal replacement Therapy in Patients with Systemic Sepsis. Eg J Anaesth. 2009; 25: 453-61.
    • (2009) Eg J Anaesth , vol.25 , pp. 453-461
    • Moemen, E.1
  • 31
    • 43449137017 scopus 로고    scopus 로고
    • Intermittent Hemodialysis Versus Continuous Renal Replacement Therapy for Acute Renal Failure in the Intensive Care Unit: An Observational Outcomes Analysis
    • Rauf A, Long K, Gajic O, Anderson SS, Swaminathan L, Albright RC. Intermittent Hemodialysis Versus Continuous Renal Replacement Therapy for Acute Renal Failure in the Intensive Care Unit: An Observational Outcomes Analysis. Journal of Intensive Care Medicine. 2008; 23(3): 195-203.
    • (2008) Journal of Intensive Care Medicine , vol.23 , Issue.3 , pp. 195-203
    • Rauf, A.1    Long, K.2    Gajic, O.3    Anderson, S.S.4    Swaminathan, L.5    Albright, R.C.6
  • 34
    • 84868684501 scopus 로고    scopus 로고
    • Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care
    • Myburgh JA, Finfer S, Bellomo R, Billot L, Cass A, Gattas D, et al. Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care. N Engl J Med. 2012; 367(20): 1901-11.
    • (2012) N Engl J Med , vol.367 , Issue.20 , pp. 1901-1911
    • Myburgh, J.A.1    Finfer, S.2    Bellomo, R.3    Billot, L.4    Cass, A.5    Gattas, D.6
  • 35
    • 85077805974 scopus 로고    scopus 로고
    • Food and Drug Administartion, Bethesda, Maryland, cited 2013 Jan 29]. Available from
    • Food and Drug Administartion. Risks and Benefits of Hydroxyethyl Starch Solutions [Internet]. Bethesda, Maryland; 2012 [cited 2013 Jan 29]. Available from: http://www.fda.gov/downloads/BiologicsBloodVaccines/NewsEvents/WorkshopsMeetingsC onferences/UCM321588.pdf
    • (2012) Risks and Benefits of Hydroxyethyl Starch Solutions [Internet]
  • 38
    • 33746637533 scopus 로고    scopus 로고
    • The effects of colloid solutions on hemostasis
    • Van der Linden P, Icckx B. The effects of colloid solutions on hemostasis. CAN J ANESTH. 2006; 53(6): S30-S39.
    • (2006) CAN J ANESTH , vol.53 , Issue.6
    • Van der Linden, P.1    Icckx, B.2
  • 40
    • 0034814022 scopus 로고    scopus 로고
    • The effects of balanced versus saline-based hetastarch and crystalloid solutions on acid-base and electrolyte status and gastric mucosal perfusion in elderly surgical patients
    • Wilkes NJ, Woolf R, Mutch M, Mallett SV, Peachey T, Stephens R, et al. The effects of balanced versus saline-based hetastarch and crystalloid solutions on acid-base and electrolyte status and gastric mucosal perfusion in elderly surgical patients. Anesth Analg. 2001; 93(4): 811-6.
    • (2001) Anesth Analg , vol.93 , Issue.4 , pp. 811-816
    • Wilkes, N.J.1    Woolf, R.2    Mutch, M.3    Mallett, S.V.4    Peachey, T.5    Stephens, R.6
  • 41
    • 84867504521 scopus 로고    scopus 로고
    • Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults
    • Yunos NM, Bellomo R, Hegarty C, Story D, Ho L, Bailey M. Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults. JAMA. 2012; 308(15): 1566-72.
    • (2012) JAMA , vol.308 , Issue.15 , pp. 1566-1572
    • Yunos, N.M.1    Bellomo, R.2    Hegarty, C.3    Story, D.4    Ho, L.5    Bailey, M.6
  • 42
    • 34548500382 scopus 로고    scopus 로고
    • The COASST study: Cost-effectiveness of albumin in severe sepsis and septic shock
    • Guidet B, Mosqueda GJ, Priol G, Aegerter P. The COASST study: cost-effectiveness of albumin in severe sepsis and septic shock. Journal of critical care. 2007; 22(3): 197-203.
    • (2007) Journal of Critical Care , vol.22 , Issue.3 , pp. 197-203
    • Guidet, B.1    Mosqueda, G.J.2    Priol, G.3    Aegerter, P.4
  • 45
    • 84857554756 scopus 로고    scopus 로고
    • Temporal trends in patient characteristics and survival of intensive care admissions with sepsis
    • Dreiher J, Almog Y, Sprung CL, Codish S, Klein M, Einav S, et al. Temporal trends in patient characteristics and survival of intensive care admissions with sepsis. Critical Care Medicine. 2012; 40(3): 855-60.
    • (2012) Critical Care Medicine , vol.40 , Issue.3 , pp. 855-860
    • Dreiher, J.1    Almog, Y.2    Sprung, C.L.3    Codish, S.4    Klein, M.5    Einav, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.