Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 6, 2014, Pages 1660-1666

  Hassan, Amel ^a   Lee, Pamela ^b   Maggina, Paraskevi ^c   Xu, Jin Hua ^a   Moreira, Diana ^c   Slatter, Mary ^d   Nademi, Zohreh ^c   Worth, Austen ^a   Adams, Stuart ^a   Jones, Alison ^a   Cale, Catherine ^a   Allwood, Zoe ^a   Rao, Kanchan ^a   Chiesa, Robert ^a   Amrolia, Persis ^b   Gaspar, Hubert ^b   Davies, E Graham ^b   Veys, Paul ^a   Gennery, Andrew ^d   Qasim, Waseem ^b  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c Infectious Diseases Allergy   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

adenosine deaminase deficiency; chimerism; conditioning; engraftment; natural killer cells; Severe combined immunodeficiency

Indexed keywords

ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; B LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; SEVERE COMBINED IMMUNODEFICIENCY; T LYMPHOCYTE; ADENOSINE DEAMINASE DEFICIENCY; CHILD; CHILDHOOD DISEASE; CHIMERA; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DONOR; ENGRAFTMENT; ENZYME REPLACEMENT; FAMILY; FOLLOW UP; GRAFT RECIPIENT; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; HOST; HUMORAL IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; LYMPHOCYTE COUNT; RETROSPECTIVE STUDY; SIBLING; VDJ RECOMBINATION; VIRUS REACTIVATION;

IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR;

ADENOSINE DEAMINASE DEFICIENCY; CHIMERISM; CONDITIONING; ENGRAFTMENT; NATURAL KILLER CELLS; SEVERE COMBINED IMMUNODEFICIENCY;

CELL LINEAGE; FEMALE; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; INFANT, NEWBORN; KILLER CELLS, NATURAL; MALE; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTE SUBSETS; TRANSPLANTATION CHIMERA; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS;

EID: 84901804522     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.02.042     Document Type: Article

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