Messenger RNA- versus retrovirus-based induced pluripotent stem cell reprogramming strategies: Analysis of genomic integrity

Stem Cells Translational Medicine

Volumn 3, Issue 6, 2014, Pages 686-691

  Steichen, Clara ^a,b   Luce, Eléanor ^a,b   Maluenda, Jérôme ^c   Tosca, Lucie ^d   Moreno Gimeno, Inmaculada ^e   Desterke, Christophe ^a,b   Dianat, Noushin ^a,b   Goulinet Mainot, Sylvie ^a,b   Awan Toor, Sarah ^a,b   Burks, Deborah ^e   Marie, Joëlle ^f   Weber, Anne ^a,b   Tachdjian, Gérard ^d   Melki, Judith ^c   Dubart Kupperschmitt, Anne ^a,b  

^a HÔPITAL PAUL BROUSSE   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c BICÊTRE HOSPITAL   (France)

^d HÔPITAL ANTOINE BÉCLÈRE   (France)

^e CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^f CENTRE DE GÉNÉTIQUE MOLÉCULAIRE   (France)

Author keywords

Genome integrity; Hepatic differentiation; iPSCs; mRNA reprogramming; SNP CNV analysis

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA FETOPROTEIN; CYTOKERATIN 19; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PEPTIDES AND PROTEINS; PROTEIN LIN28; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ARTICLE; COPY NUMBER VARIATION; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENOMICS; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER CELL; MICROARRAY ANALYSIS; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

GENOME INTEGRITY; HEPATIC DIFFERENTIATION; IPSCS; MRNA REPROGRAMMING; SNP/CNV ANALYSIS;

CELL DIFFERENTIATION; CELLS, CULTURED; DNA COPY NUMBER VARIATIONS; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; GENOTYPE; HEPATOCYTES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NUCLEAR REPROGRAMMING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROVIRIDAE; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84901786419     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0158     Document Type: Article

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