Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function

PLoS Genetics

Volumn 10, Issue 2, 2014, Pages

  Verster, Adrian J ^a   Ramani, Arun K ^a   McKay, Sheldon J ^b   Fraser, Andrew G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; CAENORHABDITIS ELEGANS PROTEIN;

ADULT; AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS; CAENORHABDITIS BRIGGSAE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DEVELOPMENTAL SYSTEM DRIFT; DEVELOPMENTAL, AGE AND GROWTH PARAMETERS; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE FUNCTION; GENE LIBRARY; GENE TARGETING; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MALE; MULTIGENE FAMILY; NONHUMAN; PHENOTYPE; PROTEIN ANALYSIS; RNA INTERFERENCE; SPECIES COMPARISON; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; GROWTH, DEVELOPMENT AND AGING; MOLECULAR EVOLUTION; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; PHENOTYPE; RNA INTERFERENCE; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

EID: 84901742083     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004077     Document Type: Article

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