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Volumn 45, Issue 2, 2014, Pages 161-167

Elevation in multiple serum inflammatory biomarkers predicts survival of pancreatic cancer patients with inoperable disease

Author keywords

CRP; Inflammation; Pancreatic cancer; Serum ferritin

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; FERRITIN; ANTINEOPLASTIC AGENT; FLUOROURACIL; OCTREOTIDE; TUMOR MARKER;

EID: 84901684557     PISSN: 19416628     EISSN: 19416636     Source Type: Journal    
DOI: 10.1007/s12029-013-9564-9     Document Type: Article
Times cited : (14)

References (43)
  • 3
    • 0025307965 scopus 로고
    • The clinical utility of the CA 19-9 tumor-associated antigen
    • Steinberg W. The clinical utility of the CA 19-9 tumor-associated antigen. Am J Gastroenterol. 1990;85(4):350-5. (Pubitemid 20140602)
    • (1990) American Journal of Gastroenterology , vol.85 , Issue.4 , pp. 350-355
    • Steinberg, W.1
  • 7
    • 84859710888 scopus 로고    scopus 로고
    • An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice
    • Daniluk J, Liu Y, Deng D, Chu J, Huang H, Gaiser S, et al. An NF-kappaB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice. J Clin Invest. 2012;122(4):1519-28.
    • (2012) J Clin Invest , vol.122 , Issue.4 , pp. 1519-1528
    • Daniluk, J.1    Liu, Y.2    Deng, D.3    Chu, J.4    Huang, H.5    Gaiser, S.6
  • 8
    • 79958710624 scopus 로고    scopus 로고
    • Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence
    • Guerra C, Collado M, Navas C, Schuhmacher AJ, Hernandez-Porras I, Canamero M, et al. Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. Cancer Cell. 2011;19(6):728-39.
    • (2011) Cancer Cell , vol.19 , Issue.6 , pp. 728-739
    • Guerra, C.1    Collado, M.2    Navas, C.3    Schuhmacher, A.J.4    Hernandez-Porras, I.5    Canamero, M.6
  • 9
    • 79953761842 scopus 로고    scopus 로고
    • Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression
    • Fukuda A, Wang SC, Morris JP, Folias AE, Liou A, Kim GE, et al. Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell. 2011;19(4):441-55.
    • (2011) Cancer Cell , vol.19 , Issue.4 , pp. 441-455
    • Fukuda, A.1    Wang, S.C.2    Morris, J.P.3    Folias, A.E.4    Liou, A.5    Kim, G.E.6
  • 12
    • 0028933898 scopus 로고
    • Acute-phase protein response and survival duration of patients with pancreatic cancer
    • Falconer JS, Fearon KC, Ross JA, Elton R, Wigmore SJ, Garden OJ, et al. Acute-phase protein response and survival duration of patients with pancreatic cancer. Cancer. 1995;75(8):2077-82.
    • (1995) Cancer , vol.75 , Issue.8 , pp. 2077-2082
    • Falconer, J.S.1    Fearon, K.C.2    Ross, J.A.3    Elton, R.4    Wigmore, S.J.5    Garden, O.J.6
  • 13
    • 13244284643 scopus 로고    scopus 로고
    • Systemic inflammatory response predicts outcome in patients undergoing resection for ductal adenocarcinoma head of pancreas
    • DOI 10.1038/sj.bjc.6602305
    • Jamieson NB, Glen P, McMillan DC, McKay CJ, Foulis AK, Carter R, et al. Systemic inflammatory response predicts outcome in patients undergoing resection for ductal adenocarcinoma head of pancreas. Br J Cancer. 2005;92(1):21-3. (Pubitemid 40188430)
    • (2005) British Journal of Cancer , vol.92 , Issue.1 , pp. 21-23
    • Jamieson, N.B.1    Glen, P.2    McMillan, D.C.3    McKay, C.J.4    Foulis, A.K.5    Carter, R.6    Imrie, C.W.7
  • 14
    • 34248579658 scopus 로고    scopus 로고
    • Predictive factors in pancreatic ductal adenocarcinoma: Role of the inflammatory response
    • DOI 10.1080/00365520601058452, PII 778612404
    • Tingstedt B, Johansson P, Andersson B, Andersson R. Predictive factors in pancreatic ductal adenocarcinoma: role of the inflammatory response. Scand J Gastroenterol. 2007;42(6):754-9. (Pubitemid 46763583)
    • (2007) Scandinavian Journal of Gastroenterology , vol.42 , Issue.6 , pp. 754-759
    • Tingstedt, B.1    Johansson, P.2    Andersson, B.3    Andersson, R.4
  • 15
    • 84868136449 scopus 로고    scopus 로고
    • Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study
    • Kalousova M, Krechler T, Jachymova M, Kubena AA, Zak A, Zima T. Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study. Tumour Biol. 2012;33(5):1695-700.
    • (2012) Tumour Biol , vol.33 , Issue.5 , pp. 1695-1700
    • Kalousova, M.1    Krechler, T.2    Jachymova, M.3    Kubena, A.A.4    Zak, A.5    Zima, T.6
  • 17
    • 33845441144 scopus 로고    scopus 로고
    • Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey
    • DOI 10.1161/CIRCULATIONAHA.106.615740, PII 0000301720061205000008
    • Crawford DC, Sanders CL, Qin X, Smith JD, Shephard C, Wong M, et al. Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey. Circulation. 2006;114(23):2458-65. (Pubitemid 44901518)
    • (2006) Circulation , vol.114 , Issue.23 , pp. 2458-2465
    • Crawford, D.C.1    Sanders, C.L.2    Qin, X.3    Smith, J.D.4    Shephard, C.5    Wong, M.6    Witrak, L.7    Rieder, M.J.8    Nickerson, D.A.9
  • 18
    • 0037022237 scopus 로고    scopus 로고
    • Weight loss reduces C-reactive protein levels in obese postmenopausal women
    • DOI 10.1161/hc0502.103331
    • Tchernof A, Nolan A, Sites CK, Ades PA, Poehlman ET. Weight loss reduces C-reactive protein levels in obese postmenopausal women. Circulation. 2002;105(5):564-9. (Pubitemid 34123429)
    • (2002) Circulation , vol.105 , Issue.5 , pp. 564-569
    • Tchernof, A.1    Nolan, A.2    Sites, C.K.3    Ades, P.A.4    Poehlman, E.T.5
  • 19
    • 79951677811 scopus 로고    scopus 로고
    • C-reactive protein levels and body mass index: Elucidating direction of causation through reciprocal Mendelian randomization
    • Lond
    • Timpson NJ, Nordestgaard BG, Harbord RM, Zacho J, Frayling TM, Tybjaerg-Hansen A, et al. C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization. Int J Obes (Lond). 2011;35(2):300-8.
    • (2011) Int J Obes , vol.35 , Issue.2 , pp. 300-308
    • Timpson, N.J.1    Nordestgaard, B.G.2    Harbord, R.M.3    Zacho, J.4    Frayling, T.M.5    Tybjaerg-Hansen, A.6
  • 20
    • 0026074439 scopus 로고
    • Hepatic changes and serum ferritin in pancreatic cancer and other gastrointestinal diseases: The role of cholestasis
    • Basso D, Fabris C, Del Favero G, Meggiato T, Panozzo MP, Vianello D, et al. Hepatic changes and serum ferritin in pancreatic cancer and other gastrointestinal diseases: the role of cholestasis. Ann Clin Biochem. 1991;28(Pt 1):34-8.
    • (1991) Ann Clin Biochem , vol.28 , Issue.PART 1 , pp. 34-38
    • Basso, D.1    Fabris, C.2    Del Favero, G.3    Meggiato, T.4    Panozzo, M.P.5    Vianello, D.6
  • 22
    • 0021994887 scopus 로고
    • Prognostic importance of serum ferritin in patients with Stages III and IV neuroblastoma: The childrens cancer study group experience
    • Hann HW, Evans AE, Siegel SE, Wong KY, Sather H, Dalton A, et al. Prognostic importance of serum ferritin in patients with stages III and IV neuroblastoma: the Childrens Cancer Study Group experience. Cancer Res. 1985;45(6):2843-8. (Pubitemid 15232759)
    • (1985) Cancer Research , vol.45 , Issue.6 , pp. 2843-2848
    • Hann, H.W.L.1    Evans, A.E.2    Siegel, S.E.3
  • 23
    • 84871540704 scopus 로고    scopus 로고
    • Elevation in inflammatory serum biomarkers predicts response to trastuzumab-containing therapy
    • Alkhateeb A, Leitzel K, Ali SM, Campbell-Baird C, Evans M, Fuchs E, et al. Elevation in inflammatory serum biomarkers predicts response to trastuzumab-containing therapy. PLoS One. 2012;7(12):e51379.
    • (2012) PLoS One , vol.7 , Issue.12
    • Alkhateeb, A.1    Leitzel, K.2    Ali, S.M.3    Campbell-Baird, C.4    Evans, M.5    Fuchs, E.6
  • 24
    • 78650908746 scopus 로고    scopus 로고
    • Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion
    • De Domenico I, Vaughn MB, Paradkar PN, Lo E, Ward DM, Kaplan J. Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion. Cell Metab. 2011;13(1):57-67.
    • (2011) Cell Metab , vol.13 , Issue.1 , pp. 57-67
    • De Domenico, I.1    Vaughn, M.B.2    Paradkar, P.N.3    Lo, E.4    Ward, D.M.5    Kaplan, J.6
  • 25
    • 77956605615 scopus 로고    scopus 로고
    • Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway
    • Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, et al. Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood. 2010;116(9):1574-84.
    • (2010) Blood , vol.116 , Issue.9 , pp. 1574-1584
    • Cohen, L.A.1    Gutierrez, L.2    Weiss, A.3    Leichtmann-Bardoogo, Y.4    Zhang, D.L.5    Crooks, D.R.6
  • 26
    • 60249084746 scopus 로고    scopus 로고
    • Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism
    • Ferring-Appel D, Hentze MW, Galy B. Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism. Blood. 2009;113(3):679-87.
    • (2009) Blood , vol.113 , Issue.3 , pp. 679-687
    • Ferring-Appel, D.1    Hentze, M.W.2    Galy, B.3
  • 28
    • 0024496308 scopus 로고
    • Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis
    • Broxmeyer HE, Williams DE, Geissler K, Hangoc G, Cooper S, Bicknell DC, et al. Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis. Blood. 1989;73(1):74-9. (Pubitemid 19040956)
    • (1989) Blood , vol.73 , Issue.1 , pp. 74-79
    • Broxmeyer, H.E.1    Williams, D.E.2    Geissler, K.3    Hangoc, G.4    Cooper, S.5    Bicknell, D.C.6    Levi, S.7    Arosio, P.8
  • 29
    • 79954616688 scopus 로고    scopus 로고
    • H-ferritin is the major source of iron for oligodendrocytes
    • Todorich B, Zhang X, Connor JR. H-ferritin is the major source of iron for oligodendrocytes. Glia. 2011;59(6):927-35.
    • (2011) Glia , vol.59 , Issue.6 , pp. 927-935
    • Todorich, B.1    Zhang, X.2    Connor, J.R.3
  • 30
    • 79954600458 scopus 로고    scopus 로고
    • Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
    • Kurahara H, Shinchi H, Mataki Y, Maemura K, Noma H, Kubo F, et al. Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res. 2011;167(2):e211-9.
    • (2011) J Surg Res , vol.167 , Issue.2
    • Kurahara, H.1    Shinchi, H.2    Mataki, Y.3    Maemura, K.4    Noma, H.5    Kubo, F.6
  • 31
    • 84876141188 scopus 로고    scopus 로고
    • Analysis of pancreatic cancer microenvironment: Role of macrophage infiltrates and growth factors expression
    • Gardian K, Janczewska S, Olszewski WL, Durlik M. Analysis of pancreatic cancer microenvironment: role of macrophage infiltrates and growth factors expression. J Cancer. 2012;3:285-91.
    • (2012) J Cancer , vol.3 , pp. 285-291
    • Gardian, K.1    Janczewska, S.2    Olszewski, W.L.3    Durlik, M.4
  • 32
    • 0000048607 scopus 로고    scopus 로고
    • Phase 3 trial of SMS 201-995 pa LAR (SMS PA LAR) and continuous infusion (CI) 5-FU in unresectable stage II, III, and IV pancreatic cancer
    • Roy A, Jacobs A, Bukowski R, Cunningham D, Hamm J, Schlag PM, et al. Phase 3 trial of SMS 201-995 pa LAR (SMS PA LAR) and continuous infusion (CI) 5-FU in unresectable stage II, III, and IV pancreatic cancer. Proc ASCO Annu Meeting. 1998;17(987):257.
    • (1998) Proc ASCO Annu Meeting , vol.17 , Issue.987 , pp. 257
    • Roy, A.1    Jacobs, A.2    Bukowski, R.3    Cunningham, D.4    Hamm, J.5    Schlag, P.M.6
  • 33
    • 77954650702 scopus 로고    scopus 로고
    • Prognostic relevance of CA 19-9, CEA, CRP, and LDH kinetics in patients treated with palliative second-line therapy for advanced pancreatic cancer
    • Haas M, Laubender RP, Stieber P, Holdenrieder S, Bruns CJ, Wilkowski R, et al. Prognostic relevance of CA 19-9, CEA, CRP, and LDH kinetics in patients treated with palliative second-line therapy for advanced pancreatic cancer. Tumour Biol. 2010;31(4):351-7.
    • (2010) Tumour Biol , vol.31 , Issue.4 , pp. 351-357
    • Haas, M.1    Laubender, R.P.2    Stieber, P.3    Holdenrieder, S.4    Bruns, C.J.5    Wilkowski, R.6
  • 35
    • 4644243396 scopus 로고    scopus 로고
    • Serum ferritin and risk of the metabolic syndrome in U.S. adults
    • DOI 10.2337/diacare.27.10.2422
    • Jehn M, Clark JM, Guallar E. Serum ferritin and risk of the metabolic syndrome in U.S. adults. Diabetes Care. 2004;27(10):2422-8. (Pubitemid 39281396)
    • (2004) Diabetes Care , vol.27 , Issue.10 , pp. 2422-2428
    • Jehn, M.1    Clark, J.M.2    Guallar, E.3
  • 36
    • 1642443851 scopus 로고    scopus 로고
    • Mediators of inflammation and acute phase response in the liver
    • Noisy-le-grand
    • Streetz KL, Wustefeld T, Klein C, Manns MP, Trautwein C. Mediators of inflammation and acute phase response in the liver. Cell Mol Biol (Noisy-le-grand). 2001;47(4):661-73.
    • (2001) Cell Mol Biol , vol.47 , Issue.4 , pp. 661-673
    • Streetz, K.L.1    Wustefeld, T.2    Klein, C.3    Manns, M.P.4    Trautwein, C.5
  • 37
    • 20144379879 scopus 로고    scopus 로고
    • Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: New evidence for direct antiinflammatory effects of statins
    • DOI 10.1161/01.ATV.0000163840.63685.0c
    • Arnaud C, Burger F, Steffens S, Veillard NR, Nguyen TH, Trono D, et al. Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins. Arterioscler Thromb Vasc Biol. 2005;25(6):1231-6. (Pubitemid 40776614)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.6 , pp. 1231-1236
    • Arnaud, C.1    Burger, F.2    Steffens, S.3    Veillard, N.R.4    Nguyen, T.H.5    Trono, D.6    Mach, F.7
  • 38
    • 0031454793 scopus 로고    scopus 로고
    • Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron
    • Tran TN, Eubanks SK, Schaffer KJ, Zhou CY, Linder MC. Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood. 1997;90(12):4979-86. (Pubitemid 28007214)
    • (1997) Blood , vol.90 , Issue.12 , pp. 4979-4986
    • Tran, T.N.1    Eubanks, S.K.2    Schaffer, K.J.3    Zhou, C.Y.J.4    Linder, M.C.5
  • 40
    • 0031857792 scopus 로고    scopus 로고
    • Regulation of iron metabolism in the acute-phase response: Interferon gamma and tumour necrosis factor alpha induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients
    • DOI 10.1046/j.1365-2362.1998.00323.x
    • Feelders RA, Vreugdenhil G, Eggermont AM, Kuiper-Kramer PA, van Eijk HG, Swaak AJ. Regulation of iron metabolism in the acute-phase response: interferon gamma and tumour necrosis factor alpha induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients. Eur J Clin Invest. 1998;28(7):520-7. (Pubitemid 28350015)
    • (1998) European Journal of Clinical Investigation , vol.28 , Issue.7 , pp. 520-527
    • Feelders, R.A.1    Vreugdenhil, G.2    Eggermont, A.M.M.3    Kuiper-Kramer, P.A.4    Van Eijk, H.G.5    Swaak, A.J.G.6
  • 41
    • 0026040435 scopus 로고
    • Specific binding sites for H-ferritin on human lymphocytes: Modulation during cellular proliferation and potential implication in cell growth control
    • Fargion S, Fracanzani AL, Brando B, Arosio P, Levi S, Fiorelli G. Specific binding sites for H-ferritin on human lymphocytes: modulation during cellular proliferation and potential implication in cell growth control. Blood. 1991;78(4):1056-61.
    • (1991) Blood , vol.78 , Issue.4 , pp. 1056-1061
    • Fargion, S.1    Fracanzani, A.L.2    Brando, B.3    Arosio, P.4    Levi, S.5    Fiorelli, G.6
  • 42
    • 58149477863 scopus 로고    scopus 로고
    • Scara5 is a ferritin receptor mediating non-transferrin iron delivery
    • Li JY, Paragas N, Ned RM, Qiu A, Viltard M, Leete T, et al. Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev Cell. 2009;16(1):35-46.
    • (2009) Dev Cell , vol.16 , Issue.1 , pp. 35-46
    • Li, J.Y.1    Paragas, N.2    Ned, R.M.3    Qiu, A.4    Viltard, M.5    Leete, T.6
  • 43
    • 84879334969 scopus 로고    scopus 로고
    • Ferritin stimulates breast cancer cells through an iron-independent mechanism and is primarily localized within tumor-associated macrophages
    • Alkhateeb A, Han B, Connor JR. Ferritin stimulates breast cancer cells through an iron-independent mechanism and is primarily localized within tumor-associated macrophages. Breast Cancer Res Treat. 2013;137(3):733-44.
    • (2013) Breast Cancer Res Treat , vol.137 , Issue.3 , pp. 733-744
    • Alkhateeb, A.1    Han, B.2    Connor, J.R.3


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