Interactions between chromosomal and nonchromosomal elements reveal missing heritability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 21, 2014, Pages 7719-7722

  Edwards, Matthew D ^a   Symbor Nagrabska, Anna ^b   Dollard, Lindsey ^b   Gifford, David K ^a,b,c,d   Fink, Gerald R ^b,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Extrachromosomal; Genetic interactions; Nonlinear model

Indexed keywords

ARTICLE; CHROMOSOME; CHROMOSOME VARIANT; CYTOPLASM; DNA SEQUENCE; GENE DELETION; GENE INTERACTION; GENE SEQUENCE; GENETIC TRAIT; HAPLOIDY; HERITABILITY; INDEL MUTATION; INTERACTIONS WITH RNA; LOSS OF FUNCTION MUTATION; MITOCHONDRIAL GENOME; MITOCHONDRION; NATURAL POPULATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGENY; RNA VIRUS; SINGLE NUCLEOTIDE POLYMORPHISM;

EXTRACHROMOSOMAL; GENETIC INTERACTIONS; NONLINEAR MODEL;

ANALYSIS OF VARIANCE; CHROMOSOMES; COMPUTATIONAL BIOLOGY; EXTRACHROMOSOMAL INHERITANCE; GENE FREQUENCY; GENETIC THERAPY; HUMANS; MITOCHONDRIAL DISEASES; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; YEASTS;

EID: 84901684215     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1407126111     Document Type: Article

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