A catch-up validation study of an in vitro skin irritation test method using reconstructed human epidermis LabCyte EPI-MODEL24

Journal of Applied Toxicology

Volumn 34, Issue 7, 2014, Pages 766-774

  Kojima, Hajime ^a   Katoh, Masakazu ^b   Shinoda, Shinsuke ^c   Hagiwara, Saori ^c   Suzuki, Tamie ^d   Izumi, Runa ^d   Yamaguchi, Yoshihiro ^e   Nakamura, Maki ^e   Kasahawa, Toshihiko ^f   Shibai, Aya ^f  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b Japan Tissue Engineering Co Ltd   (Japan)

^c Drug Safety Testing Centre Co Ltd   (Japan)

^d Central Research Development Laboratory Fancl Corporation   (Japan)

^e Kobayashi Pharmaceutical Co   (Japan)

^f FUJIFILM CORPORATION   (Japan)

Author keywords

Catch up; In vitro; Reconstructed human epidermis; Skin irritation; Validation

Indexed keywords

1 BROMOHEXANE; HEXANE; UNCLASSIFIED DRUG; IRRITANT AGENT;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; EPIDERMIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; SKIN IRRITATION; SKIN IRRITATION TEST; SKIN TEST; VALIDATION STUDY; 3T3 CELL LINE; ANIMAL; ANIMAL TESTING ALTERNATIVE; CELL LINE; CELL PROLIFERATION; CHEMICALLY INDUCED; DRUG EFFECTS; KERATINOCYTE; METABOLISM; MOUSE; PROCEDURES; SKIN DISEASE; TOXICITY; TOXICITY TESTING;

ANIMALIA;

3T3 CELLS; ANIMAL TESTING ALTERNATIVES; ANIMALS; CELL LINE; CELL PROLIFERATION; EPIDERMIS; HUMANS; IRRITANTS; KERATINOCYTES; MICE; SKIN DISEASES; SKIN IRRITANCY TESTS;

EID: 84901639313     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2937     Document Type: Article

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