-
1
-
-
84862161013
-
Treating hepatitis C: current standard of care and emerging direct-acting antiviral agents
-
Poordad F, Dieterich D. Treating hepatitis C: current standard of care and emerging direct-acting antiviral agents. J Viral Hepat 2012; 19(7): 449-464.
-
(2012)
J Viral Hepat
, vol.19
, Issue.7
, pp. 449-464
-
-
Poordad, F.1
Dieterich, D.2
-
2
-
-
77953416889
-
New direct-acting antivirals in the development for hepatitis C virus infection
-
Pockros PJ. New direct-acting antivirals in the development for hepatitis C virus infection. Therap Adv Gastroenterol 2010; 3(3): 191-202.
-
(2010)
Therap Adv Gastroenterol
, vol.3
, Issue.3
, pp. 191-202
-
-
Pockros, P.J.1
-
5
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
SPRINT-2 Investigators
-
Poordad F, McCone J Jr, Bacon BR, Bruno S, Manns MP, Sulkowski MS, Jacobson IM, Reddy KR, Goodman ZD, Boparai N, DiNubile MJ, Sniukiene V, Brass CA, Albrecht JK, Bronowicki JP; SPRINT-2 Investigators. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364(13): 1195-1206.
-
(2011)
N Engl J Med
, vol.364
, Issue.13
, pp. 1195-1206
-
-
Poordad, F.1
McCone Jr., J.2
Bacon, B.R.3
Bruno, S.4
Manns, M.P.5
Sulkowski, M.S.6
Jacobson, I.M.7
Reddy, K.R.8
Goodman, Z.D.9
Boparai, N.10
DiNubile, M.J.11
Sniukiene, V.12
Brass, C.A.13
Albrecht, J.K.14
Bronowicki, J.P.15
-
6
-
-
79959438789
-
Telaprevir for previously untreated chronic hepatitis C virus infection
-
ADVANCE Study Team
-
Jacobson IM, McHutchison JG, Dusheiko G, Di Bisceglie AM, Reddy KR, Bzowej NH, Marcellin P, Muir AJ, Ferenci P, Flisiak R, George J, Rizzetto M, Shouval D, Sola R, Terg RA, Yoshida EM, Adda N, Bengtsson L, Sankoh AJ, Kieffer TL, George S, Kauffman RS, Zeuzem S; ADVANCE Study Team. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011; 364(25): 2405-2416.
-
(2011)
N Engl J Med
, vol.364
, Issue.25
, pp. 2405-2416
-
-
Jacobson, I.M.1
McHutchison, J.G.2
Dusheiko, G.3
Di Bisceglie, A.M.4
Reddy, K.R.5
Bzowej, N.H.6
Marcellin, P.7
Muir, A.J.8
Ferenci, P.9
Flisiak, R.10
George, J.11
Rizzetto, M.12
Shouval, D.13
Sola, R.14
Terg, R.A.15
Yoshida, E.M.16
Adda, N.17
Bengtsson, L.18
Sankoh, A.J.19
Kieffer, T.L.20
George, S.21
Kauffman, R.S.22
Zeuzem, S.23
more..
-
7
-
-
77950817619
-
Telaprevir for previously treated chronic HCV infection
-
PROVE3 Study Team
-
McHutchison JG, Manns MP, Muir AJ, Terrault NA, Jacobson IM, Afdhal NH, Heathcote EJ, Zeuzem S, Reesink HW, Garg J, Bsharat M, George S, Kauffman RS, Adda N, Di Bisceglie AM; PROVE3 Study Team. Telaprevir for previously treated chronic HCV infection. N Engl J Med 2010; 362(14): 1292-1303.
-
(2010)
N Engl J Med
, vol.362
, Issue.14
, pp. 1292-1303
-
-
McHutchison, J.G.1
Manns, M.P.2
Muir, A.J.3
Terrault, N.A.4
Jacobson, I.M.5
Afdhal, N.H.6
Heathcote, E.J.7
Zeuzem, S.8
Reesink, H.W.9
Garg, J.10
Bsharat, M.11
George, S.12
Kauffman, R.S.13
Adda, N.14
Di Bisceglie, A.M.15
-
8
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
HCV RESPOND-2 Investigators
-
Bacon BR, Gordon SC, Lawitz E, Marcellin P, Vierling JM, Zeuzem S, Poordad F, Goodman ZD, Sings HL, Boparai N, Burroughs M, Brass CA, Albrecht JK, Esteban R; HCV RESPOND-2 Investigators. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364(13): 1207-1217.
-
(2011)
N Engl J Med
, vol.364
, Issue.13
, pp. 1207-1217
-
-
Bacon, B.R.1
Gordon, S.C.2
Lawitz, E.3
Marcellin, P.4
Vierling, J.M.5
Zeuzem, S.6
Poordad, F.7
Goodman, Z.D.8
Sings, H.L.9
Boparai, N.10
Burroughs, M.11
Brass, C.A.12
Albrecht, J.K.13
Esteban, R.14
-
10
-
-
84863860109
-
Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b
-
Suzuki F, Sezaki H, Akuta N, Suzuki Y, Seko Y, Kawamura Y, Hosaka T, Kobayashi M, Saito S, Arase Y, Ikeda K, Kobayashi M, Mineta R, Watahiki S, Miyakawa Y, Kumada H. Prevalence of hepatitis C virus variants resistant to NS3 protease inhibitors or the NS5A inhibitor (BMS-790052) in hepatitis patients with genotype 1b. J Clin Virol 2012; 54(4): 352-354.
-
(2012)
J Clin Virol
, vol.54
, Issue.4
, pp. 352-354
-
-
Suzuki, F.1
Sezaki, H.2
Akuta, N.3
Suzuki, Y.4
Seko, Y.5
Kawamura, Y.6
Hosaka, T.7
Kobayashi, M.8
Saito, S.9
Arase, Y.10
Ikeda, K.11
Kobayashi, M.12
Mineta, R.13
Watahiki, S.14
Miyakawa, Y.15
Kumada, H.16
-
11
-
-
84880538921
-
Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance
-
Ali A, Aydin C, Gildemeister R, Romano KP, Cao H, Ozen A, Soumana D, Newton A, Petropoulos CJ, Huang W, Schiffer CA. Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance. ACS Chem Biol 2013; 8(7): 1469-1478.
-
(2013)
ACS Chem Biol
, vol.8
, Issue.7
, pp. 1469-1478
-
-
Ali, A.1
Aydin, C.2
Gildemeister, R.3
Romano, K.P.4
Cao, H.5
Ozen, A.6
Soumana, D.7
Newton, A.8
Petropoulos, C.J.9
Huang, W.10
Schiffer, C.A.11
-
12
-
-
84871118829
-
What are the promising new therapies in the field of chronic hepatitis C after the first-generation direct-acting antivirals?
-
Hunt D, Pockros P. What are the promising new therapies in the field of chronic hepatitis C after the first-generation direct-acting antivirals? Curr Gastroenterol Rep 2013; 15(1): 303.
-
(2013)
Curr Gastroenterol Rep
, vol.15
, Issue.1
, pp. 303
-
-
Hunt, D.1
Pockros, P.2
-
13
-
-
84901585653
-
-
Prescribing Information for OLYSIOTM simeprevir
-
Prescribing Information for OLYSIOTM (simeprevir): Janssen Therapeutics, Division of Janssen Products, LP, Titusville NJ 08560. Issued November 2013.
-
(2013)
Janssen Therapeutics
-
-
-
14
-
-
4444377616
-
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
-
Evans MJ, Rice CM, Goff SP. Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication. Proc Natl Acad Sci USA 2004; 101(35): 13038-13043.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.35
, pp. 13038-13043
-
-
Evans, M.J.1
Rice, C.M.2
Goff, S.P.3
-
15
-
-
42949145532
-
Regulation of hepatitis C virion production via phosphorylation of the NS5A protein
-
Tellinghuisen TL, Foss KL, Treadaway J. Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog 2008; 4(3): e1000032.
-
(2008)
PLoS Pathog
, vol.4
, Issue.3
-
-
Tellinghuisen, T.L.1
Foss, K.L.2
Treadaway, J.3
-
16
-
-
77952035218
-
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
-
Gao M, Nettles RE, Belema M, Snyder LB, Nguyen VN, Fridell RA, Serrano-Wu MH, Langley DR, Sun JH, O'Boyle DR 2nd, Lemm JA, Wang C, Knipe JO, Chien C, Colonno RJ, Grasela DM, Meanwell NA, Hamann LG. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. Nature 2010; 465(7294): 96-100.
-
(2010)
Nature
, vol.465
, Issue.7294
, pp. 96-100
-
-
Gao, M.1
Nettles, R.E.2
Belema, M.3
Snyder, L.B.4
Nguyen, V.N.5
Fridell, R.A.6
Serrano-Wu, M.H.7
Langley, D.R.8
Sun, J.H.9
O'Boyle 2nd, D.R.10
Lemm, J.A.11
Wang, C.12
Knipe, J.O.13
Chien, C.14
Colonno, R.J.15
Grasela, D.M.16
Meanwell, N.A.17
Hamann, L.G.18
-
18
-
-
84893786201
-
No resistance detected in four phase 3 clinical studies in HCV genotype 1-6 of sofosbuvir + ribavirin with or without peginterferon
-
Svarovskaia ES, Dvory HS, Hebner C, et al. No resistance detected in four phase 3 clinical studies in HCV genotype 1-6 of sofosbuvir + ribavirin with or without peginterferon. Hepatology 2013; 58(4 Suppl): 1091A-1092A (abstract No. 1843).
-
(2013)
Hepatology
, vol.58
, Issue.4 SUPPL.
-
-
Svarovskaia, E.S.1
Dvory, H.S.2
Hebner, C.3
-
19
-
-
84879602208
-
Comprehensive resistance testing in patients who relapsed after treatment with sofosbuvir (GS-7977)-containing regimens in phase 2 studies
-
Svarovskaia ES, Dvory-Sobol H, Gontcharova V, et al. Comprehensive resistance testing in patients who relapsed after treatment with sofosbuvir (GS-7977)-containing regimens in phase 2 studies. Hepatology 2012; 56(4 Suppl): 551A (abstract No. 753).
-
(2012)
Hepatology
, vol.56
, Issue.4 SUPPL.
-
-
Svarovskaia, E.S.1
Dvory-Sobol, H.2
Gontcharova, V.3
-
20
-
-
84878976866
-
Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial
-
Kowdley KV, Lawitz E, Crespo I, Hassanein T, Davis MN, DeMicco M, Bernstein DE, Afdhal N, Vierling JM, Gordon SC, Anderson JK, Hyland RH, Dvory-Sobol H, An D, Hindes RG, Albanis E, Symonds WT, Berrey MM, Nelson DR, Jacobson IM. Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial. Lancet 2013; 381(9883): 2100-2107.
-
(2013)
Lancet
, vol.381
, Issue.9883
, pp. 2100-2107
-
-
Kowdley, K.V.1
Lawitz, E.2
Crespo, I.3
Hassanein, T.4
Davis, M.N.5
DeMicco, M.6
Bernstein, D.E.7
Afdhal, N.8
Vierling, J.M.9
Gordon, S.C.10
Anderson, J.K.11
Hyland, R.H.12
Dvory-Sobol, H.13
An, D.14
Hindes, R.G.15
Albanis, E.16
Symonds, W.T.17
Berrey, M.M.18
Nelson, D.R.19
Jacobson, I.M.20
more..
-
21
-
-
84876740954
-
Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for noncirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial
-
Lawitz E, Lalezari JP, Hassanein T, Kowdley KV, Poordad FF, Sheikh AM, Afdhal NH, Bernstein DE, Dejesus E, Freilich B, Nelson DR, Dieterich DT, Jacobson IM, Jensen D, Abrams GA, Darling JM, Rodriguez-Torres M, Reddy KR, Sulkowski MS, Bzowej NH, Hyland RH, Mo H, Lin M, Mader M, Hindes R, Albanis E, Symonds WT, Berrey MM, Muir A. Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for noncirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial. Lancet Infect Dis 2013; 13(5): 401-408.
-
(2013)
Lancet Infect Dis
, vol.13
, Issue.5
, pp. 401-408
-
-
Lawitz, E.1
Lalezari, J.P.2
Hassanein, T.3
Kowdley, K.V.4
Poordad, F.F.5
Sheikh, A.M.6
Afdhal, N.H.7
Bernstein, D.E.8
Dejesus, E.9
Freilich, B.10
Nelson, D.R.11
Dieterich, D.T.12
Jacobson, I.M.13
Jensen, D.14
Abrams, G.A.15
Darling, J.M.16
Rodriguez-Torres, M.17
Reddy, K.R.18
Sulkowski, M.S.19
Bzowej, N.H.20
Hyland, R.H.21
Mo, H.22
Lin, M.23
Mader, M.24
Hindes, R.25
Albanis, E.26
Symonds, W.T.27
Berrey, M.M.28
Muir, A.29
more..
-
22
-
-
84871814966
-
Nucleotide polymerase inhibitor sofosbuvir plus ribavirin for hepatitis C
-
Gane EJ, Stedman CA, Hyland RH, Ding X, Svarovskaia E, Symonds WT, Hindes RG, Berrey MM. Nucleotide polymerase inhibitor sofosbuvir plus ribavirin for hepatitis C. N Engl J Med 2013; 368(1): 34-44.
-
(2013)
N Engl J Med
, vol.368
, Issue.1
, pp. 34-44
-
-
Gane, E.J.1
Stedman, C.A.2
Hyland, R.H.3
Ding, X.4
Svarovskaia, E.5
Symonds, W.T.6
Hindes, R.G.7
Berrey, M.M.8
-
23
-
-
84877730954
-
Sofosbuvir for previously untreated chronic hepatitis C infection
-
Lawitz E, Mangia A, Wyles D, Rodriguez-Torres M, Hassanein T, Gordon SC, Schultz M, Davis MN, Kayali Z, Reddy KR, Jacobson IM, Kowdley KV, Nyberg L, Subramanian GM, Hyland RH, Arterburn S, Jiang D, McNally J, Brainard D, Symonds WT, McHutchison JG, Sheikh AM, Younossi Z, Gane EJ. Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med 2013; 368(20): 1878-1887.
-
(2013)
N Engl J Med
, vol.368
, Issue.20
, pp. 1878-1887
-
-
Lawitz, E.1
Mangia, A.2
Wyles, D.3
Rodriguez-Torres, M.4
Hassanein, T.5
Gordon, S.C.6
Schultz, M.7
Davis, M.N.8
Kayali, Z.9
Reddy, K.R.10
Jacobson, I.M.11
Kowdley, K.V.12
Nyberg, L.13
Subramanian, G.M.14
Hyland, R.H.15
Arterburn, S.16
Jiang, D.17
McNally, J.18
Brainard, D.19
Symonds, W.T.20
McHutchison, J.G.21
Sheikh, A.M.22
Younossi, Z.23
Gane, E.J.24
more..
-
24
-
-
84877739274
-
Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options
-
Jacobson IM, Gordon SC, Kowdley KV, Yoshida EM, Rodriguez-Torres M, Sulkowski MS, Shiffman ML, Lawitz E, Everson G, Bennett M, Schiff E, Al-Assi MT, Subramanian GM, An D, Lin M, McNally J, Brainard D, Symonds WT, McHutchison JG, Patel K, Feld J, Pianko S, Nelson DR; POSITRON Study; FUSION Study. Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options. N Engl J Med 2013; 368(20): 1867-1877.
-
(2013)
N Engl J Med
, vol.368
, Issue.20
, pp. 1867-1877
-
-
Jacobson, I.M.1
Gordon, S.C.2
Kowdley, K.V.3
Yoshida, E.M.4
Rodriguez-Torres, M.5
Sulkowski, M.S.6
Shiffman, M.L.7
Lawitz, E.8
Everson, G.9
Bennett, M.10
Schiff, E.11
Al-Assi, M.T.12
Subramanian, G.M.13
An, D.14
Lin, M.15
McNally, J.16
Brainard, D.17
Symonds, W.T.18
McHutchison, J.G.19
Patel, K.20
Feld, J.21
Pianko, S.22
Nelson, D.R.23
more..
-
25
-
-
84892751187
-
Sofosbuvir + ribavirin for 12 or 24 weeks for patients with HCV genotype 2 or 3: the VALENCE trial
-
Zeuzem S, Dusheiko GM, Salupere R, et al. Sofosbuvir + ribavirin for 12 or 24 weeks for patients with HCV genotype 2 or 3: the VALENCE trial. Hepatology 2013; 58(4 Suppl): 733A-734A (abstract No. 1085).
-
(2013)
Hepatology
, vol.58
, Issue.4 SUPPL.
-
-
Zeuzem, S.1
Dusheiko, G.M.2
Salupere, R.3
-
26
-
-
84892737595
-
All-oral therapy with sofosbuvir plus ribavirin for the treatment of HCV genotype 1, 2, and 3 infection in patients co-infected with HIV (PHOTON-1)
-
Sulkowski MS, Rodriguez-Torres M, Lalezari JP, et al. All-oral therapy with sofosbuvir plus ribavirin for the treatment of HCV genotype 1, 2, and 3 infection in patients co-infected with HIV (PHOTON-1). Hepatology 2013; 58(4 Suppl): 313A-314A (abstract No. 212).
-
(2013)
Hepatology
, vol.58
, Issue.4 SUPPL.
-
-
Sulkowski, M.S.1
Rodriguez-Torres, M.2
Lalezari, J.P.3
-
27
-
-
84892718437
-
Pretransplant sofosbuvir and ribavirin to prevent recurrence of HCV infection after liver transplantation
-
Curry MP, Forns X, Chung RT, et al. Pretransplant sofosbuvir and ribavirin to prevent recurrence of HCV infection after liver transplantation. Hepatology 2013; 58(4 Suppl): 314A-315A (abstract No. 213).
-
(2013)
Hepatology
, vol.58
, Issue.4 SUPPL.
-
-
Curry, M.P.1
Forns, X.2
Chung, R.T.3
-
28
-
-
84893716797
-
Sofosbuvir and ribavirin for the treatment of established recurrent hepatitis C infection after liver transplantation: preliminary results of a prospective, multicenter study
-
Charlton MR, Gane EJ, Manns MP, et al. Sofosbuvir and ribavirin for the treatment of established recurrent hepatitis C infection after liver transplantation: preliminary results of a prospective, multicenter study. Hepatology 2013; 58(6 Suppl): 1378A (abstract No. LB-2).
-
(2013)
Hepatology
, vol.58
, Issue.6 SUPPL.
-
-
Charlton, M.R.1
Gane, E.J.2
Manns, M.P.3
-
29
-
-
40949117600
-
The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus
-
Flisiak R, Horban A, Gallay P, Bobardt M, Selvarajah S, Wiercinska-Drapalo A, Siwak E, Cielniak I, Higersberger J, Kierkus J, Aeschlimann C, Grosgurin P, Nicolas-Métral V, Dumont JM, Porchet H, Crabbé R, Scalfaro P. The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus. Hepatology 2008; 47(3): 817-826.
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 817-826
-
-
Flisiak, R.1
Horban, A.2
Gallay, P.3
Bobardt, M.4
Selvarajah, S.5
Wiercinska-Drapalo, A.6
Siwak, E.7
Cielniak, I.8
Higersberger, J.9
Kierkus, J.10
Aeschlimann, C.11
Grosgurin, P.12
Nicolas-Métral, V.13
Dumont, J.M.14
Porchet, H.15
Crabbé, R.16
Scalfaro, P.17
-
30
-
-
66149129922
-
The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients
-
Flisiak R, Feinman SV, Jablkowski M, Horban A, Kryczka W, Pawlowska M, Heathcote JE, Mazzella G, Vandelli C, Nicolas-Métral V, Grosgurin P, Liz JS, Scalfaro P, Porchet H, Crabbé R. The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients. Hepatology 2009; 49(5): 1460-1468.
-
(2009)
Hepatology
, vol.49
, Issue.5
, pp. 1460-1468
-
-
Flisiak, R.1
Feinman, S.V.2
Jablkowski, M.3
Horban, A.4
Kryczka, W.5
Pawlowska, M.6
Heathcote, J.E.7
Mazzella, G.8
Vandelli, C.9
Nicolas-Métral, V.10
Grosgurin, P.11
Liz, J.S.12
Scalfaro, P.13
Porchet, H.14
Crabbé, R.15
-
32
-
-
84890947330
-
Novel therapeutic approaches for hepatitis C
-
Au J, Pockros PJ. Novel therapeutic approaches for hepatitis C. Clin Pharmacol Ther 2014; 95(1): 78-88.
-
(2014)
Clin Pharmacol Ther
, vol.95
, Issue.1
, pp. 78-88
-
-
Au, J.1
Pockros, P.J.2
-
33
-
-
84894621765
-
Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial
-
Lawitz E, Poordad FF, Pang PS, Hyland RH, Ding X, Mo H, Symonds WT, McHutchison JG, Membreno FE. Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial. Lancet 2014; 383(9916): 515-523.
-
(2014)
Lancet
, vol.383
, Issue.9916
, pp. 515-523
-
-
Lawitz, E.1
Poordad, F.F.2
Pang, P.S.3
Hyland, R.H.4
Ding, X.5
Mo, H.6
Symonds, W.T.7
McHutchison, J.G.8
Membreno, F.E.9
-
34
-
-
84901631806
-
-
64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract 73
-
Gane EJ, Stedman CA, Hyland RH, et al. Once daily sofosbuvir/ledipasvir fixed dose combination with or without ribavirin: data from the ELECTRON trial. 64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract 73.
-
Once daily sofosbuvir/ledipasvir fixed dose combination with or without ribavirin: Data from the ELECTRON trial
-
-
Gane, E.J.1
Stedman, C.A.2
Hyland, R.H.3
-
35
-
-
84871765489
-
Exploratory study of oral combination antiviral therapy for hepatitis C
-
Poordad F, Lawitz E, Kowdley KV, Cohen DE, Podsadecki T, Siggelkow S, Heckaman M, Larsen L, Menon R, Koev G, Tripathi R, Pilot-Matias T, Bernstein B. Exploratory study of oral combination antiviral therapy for hepatitis C. N Engl J Med 2013; 368(1): 45-53.
-
(2013)
N Engl J Med
, vol.368
, Issue.1
, pp. 45-53
-
-
Poordad, F.1
Lawitz, E.2
Kowdley, K.V.3
Cohen, D.E.4
Podsadecki, T.5
Siggelkow, S.6
Heckaman, M.7
Larsen, L.8
Menon, R.9
Koev, G.10
Tripathi, R.11
Pilot-Matias, T.12
Bernstein, B.13
-
36
-
-
84892591928
-
Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1
-
Kowdley KV, Lawitz E, Poordad F, Cohen DE, Nelson DR, Zeuzem S, Everson GT, Kwo P, Foster GR, Sulkowski MS, Xie W, Pilot-Matias T, Liossis G, Larsen L, Khatri A, Podsadecki T, Bernstein B. Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1. N Engl J Med 2014; 370(3): 222-232.
-
(2014)
N Engl J Med
, vol.370
, Issue.3
, pp. 222-232
-
-
Kowdley, K.V.1
Lawitz, E.2
Poordad, F.3
Cohen, D.E.4
Nelson, D.R.5
Zeuzem, S.6
Everson, G.T.7
Kwo, P.8
Foster, G.R.9
Sulkowski, M.S.10
Xie, W.11
Pilot-Matias, T.12
Liossis, G.13
Larsen, L.14
Khatri, A.15
Podsadecki, T.16
Bernstein, B.17
-
37
-
-
84901631807
-
-
November 1-5, 2013, Washington, USA; abstract 1118
-
Cohen DE, Xie W, Larsen L, et al. Safety of Ribavirin-containing Regimens of ABT-450/r, ABT-333, and ABT-267 for the Treatment of HCV Genotype 1 Infection and Efficacy in Subjects with Ribavirin Dose Reductions 64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract 1118.
-
Safety of Ribavirin-containing Regimens of ABT-450/r, ABT-333, and ABT-267 for the Treatment of HCV Genotype 1 Infection and Efficacy in Subjects with Ribavirin Dose Reductions 64th Annual Meeting of the American Association for the Study of Liver diseases
-
-
Cohen, D.E.1
Xie, W.2
Larsen, L.3
-
38
-
-
84901631808
-
-
64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract LB1
-
Everson GT, Sims KD, Thuluvath PJ, et al. Phase 2b study of the interferon-free and ribavirin-free combination of daclatasvir, asunaprevir, and BMS-791325 for 12 weeks in treatment-naïve patients with chronic HCV genotype 1 infection. 64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract LB1.
-
Phase 2b study of the interferon-free and ribavirin-free combination of daclatasvir, asunaprevir, and BMS-791325 for 12 weeks in treatment-naïve patients with chronic HCV genotype 1 infection
-
-
Everson, G.T.1
Sims, K.D.2
Thuluvath, P.J.3
-
39
-
-
84856159009
-
Preliminary study of two antiviral agents for hepatitis C genotype 1
-
Lok AS, Gardiner DF, Lawitz E, Martorell C, Everson GT, Ghalib R, Reindollar R, Rustgi V, McPhee F, Wind-Rotolo M, Persson A, Zhu K, Dimitrova DI, Eley T, Guo T, Grasela DM, Pasquinelli C. Preliminary study of two antiviral agents for hepatitis C genotype 1. N Engl J Med 2012; 366(3): 216-224.
-
(2012)
N Engl J Med
, vol.366
, Issue.3
, pp. 216-224
-
-
Lok, A.S.1
Gardiner, D.F.2
Lawitz, E.3
Martorell, C.4
Everson, G.T.5
Ghalib, R.6
Reindollar, R.7
Rustgi, V.8
McPhee, F.9
Wind-Rotolo, M.10
Persson, A.11
Zhu, K.12
Dimitrova, D.I.13
Eley, T.14
Guo, T.15
Grasela, D.M.16
Pasquinelli, C.17
-
40
-
-
84892619580
-
Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection
-
AI444040 Study Group
-
Sulkowski MS, Gardiner DF, Rodriguez-Torres M, Reddy KR, Hassanein T, Jacobson I, Lawitz E, Lok AS, Hinestrosa F, Thuluvath PJ, Schwartz H, Nelson DR, Everson GT, Eley T, Wind-Rotolo M, Huang SP, Gao M, Hernandez D, McPhee F, Sherman D, Hindes R, Symonds W, Pasquinelli C, Grasela DM; AI444040 Study Group. Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection. N Engl J Med 2014; 370(3): 211-221.
-
(2014)
N Engl J Med
, vol.370
, Issue.3
, pp. 211-221
-
-
Sulkowski, M.S.1
Gardiner, D.F.2
Rodriguez-Torres, M.3
Reddy, K.R.4
Hassanein, T.5
Jacobson, I.6
Lawitz, E.7
Lok, A.S.8
Hinestrosa, F.9
Thuluvath, P.J.10
Schwartz, H.11
Nelson, D.R.12
Everson, G.T.13
Eley, T.14
Wind-Rotolo, M.15
Huang, S.P.16
Gao, M.17
Hernandez, D.18
McPhee, F.19
Sherman, D.20
Hindes, R.21
Symonds, W.22
Pasquinelli, C.23
Grasela, D.M.24
more..
-
41
-
-
84901600962
-
-
64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract 1100
-
Jacobson IM, Asselah T, Ferenci P, et al. STARTVerso3: A randomized, double-blind, placebo-controlled Phase III trial of faldaprevir in combination with pegylated interferon alfa-2a and ribavirin in treatment-experienced patients with chronic hepatitis C genotype-1 infection. 64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract 1100.
-
STARTVerso3: A randomized, double-blind, placebo-controlled Phase III trial of faldaprevir in combination with pegylated interferon alfa-2a and ribavirin in treatment-experienced patients with chronic hepatitis C genotype-1 infection
-
-
Jacobson, I.M.1
Asselah, T.2
Ferenci, P.3
-
42
-
-
84881405876
-
Faldaprevir and deleobuvir for HCV genotype 1 infection
-
Zeuzem S, Soriano V, Asselah T, Bronowicki JP, Lohse AW, Müllhaupt B, Schuchmann M, Bourlière M, Buti M, Roberts SK, Gane EJ, Stern JO, Vinisko R, Kukolj G, Gallivan JP, Böcher WO, Mensa FJ. Faldaprevir and deleobuvir for HCV genotype 1 infection. N Engl J Med 2013; 369(7): 630-639.
-
(2013)
N Engl J Med
, vol.369
, Issue.7
, pp. 630-639
-
-
Zeuzem, S.1
Soriano, V.2
Asselah, T.3
Bronowicki, J.P.4
Lohse, A.W.5
Müllhaupt, B.6
Schuchmann, M.7
Bourlière, M.8
Buti, M.9
Roberts, S.K.10
Gane, E.J.11
Stern, J.O.12
Vinisko, R.13
Kukolj, G.14
Gallivan, J.P.15
Böcher, W.O.16
Mensa, F.J.17
-
43
-
-
84892444781
-
High sustained viral response at 12- and 24-week follow-up of MK-5172 with pegylated interferon alfa-2b and ribavirin (PR) in HCV genotype 1 treatmentnaïve non-cirrhotic patients
-
Manns M, Vierling JM, Bacon BR, et al. High sustained viral response at 12- and 24-week follow-up of MK-5172 with pegylated interferon alfa-2b and ribavirin (PR) in HCV genotype 1 treatmentnaïve non-cirrhotic patients. J Hepatol 2013; 58: S30.
-
(2013)
J Hepatol
, vol.58
-
-
Manns, M.1
Vierling, J.M.2
Bacon, B.R.3
-
44
-
-
84901585650
-
-
64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract LB3
-
Jacobson IM, Ghalib RH, Rodriguez-Torres M, et al. SVR results of a once-daily regimen of simeprevir (TMC435) plus sofosbuvir (GS-7977) with or without ribavirin in cirrhotic and non-cirrhotic HCV genotype 1 treatment-naïve and prior null responder patients: the COSMOS study. 64th Annual Meeting of the American Association for the Study of Liver diseases, November 1-5, 2013, Washington, USA; abstract LB3.
-
SVR results of a once-daily regimen of simeprevir (TMC435) plus sofosbuvir (GS-7977) with or without ribavirin in cirrhotic and non-cirrhotic HCV genotype 1 treatment-naïve and prior null responder patients: The COSMOS study
-
-
Jacobson, I.M.1
Ghalib, R.H.2
Rodriguez-Torres, M.3
-
45
-
-
84894068078
-
Impact of interferon free regimens on clinical and cost outcomes for chronic hepatitis C genotype 1 patients
-
Younossi ZM, Singer ME, Mir HM, Henry L, Hunt S. Impact of interferon free regimens on clinical and cost outcomes for chronic hepatitis C genotype 1 patients. J Hepatol 2014; 60(3): 530-537.
-
(2014)
J Hepatol
, vol.60
, Issue.3
, pp. 530-537
-
-
Younossi, Z.M.1
Singer, M.E.2
Mir, H.M.3
Henry, L.4
Hunt, S.5
|