Is myopathy the Achilles' heel of statins?: Differences between the new cholesterol treatment guidelines and everyday clinical practice

Journal of the American College of Cardiology

Volumn 63, Issue 21, 2014, Pages 2300-2301

  Rallidis, Loukianos S ^a   Anastasiou Nana, Maria ^b  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN;

CHOLESTEROL BLOOD LEVEL; CLINICAL EVALUATION; CLINICAL FEATURE; CLINICAL PRACTICE; CREATINE KINASE BLOOD LEVEL; HUMAN; INCIDENCE; LETTER; MUSCLE FATIGUE; MYALGIA; MYOPATHY; PRACTICE GUIDELINE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK BENEFIT ANALYSIS; STATIN RELATED MYOPATHY; ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; MORBIDITY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT;

AMERICAN HEART ASSOCIATION; CARDIOLOGY; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CORONARY ARTERY DISEASE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA;

EID: 84901624760     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.12.047     Document Type: Letter

References (7)

1. N.J. Stone, J. Robinson, and A.H. Lichtenstein et al. ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 2013 Nov 7 [E-pub ahead of print]
2. G.A. Nichols, and C.E. Koro Does statin therapy initiation increase the risk for myopathy? An observational study of 32,225 Clin Ther 29 2007 1761 1770
3. E. Bruckert, G. Hayem, S. Dejager, C. Yau, and B. Bégaud Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients: the PRIMO study Cardiovasc Drugs Ther 19 2005 403 414
4. L.S. Rallidis, K. Foundoulaki, and M. Anastasiou-Nana Managing the underestimated risk of statin-associated myopathy Int J Cardiol 159 2012 169 176
5. Heart Protection Study Collaborative Group MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial Lancet 360 2002 7 22
6. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) Lancet 344 1994 1383 1389
7. J.C. LaRosa, S.M. Grundy, and D.D. Waters et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease N Engl J Med 352 2005 1425 1435