In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy

Photodiagnosis and Photodynamic Therapy

Volumn 11, Issue 2, 2014, Pages 204-212

  Zhao, Hongyou ^a   Yin, Rong ^b   Chen, Defu ^c   Ren, Jie ^a   Wang, Yucheng ^d   Zhanga, Jiaying ^a   Deng, Hong ^e   Wang, Ying ^a   Qiu, Haixia ^a   Huang, Naiyan ^a   Zou, Qianli ^f   Zhao, Jingquan ^e   Gu, Ying ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c BEIJING INSTITUTE OF TECHNOLOGY   (China)

^d NANKAI UNIVERSITY   (China)

^e INSTITUTE OF CHEMISTRY   (China)

^f TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY   (China)

Author keywords

Apoptosis; Hypocrellin B derivative; In vivo PDT activity; Mitochondria; PDT

Indexed keywords

CYTOCHROME C; HYPOCRELLIN B; HYPOCRELLIN B DERIVATIVE; PHOTOSENSITIZING AGENT; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PERYLENE; QUINONE DERIVATIVE; SCHIFF BASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER REGRESSION; CANCER THERAPY; CELL DAMAGE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STRUCTURE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TUMOR MODEL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; PHOTOCHEMOTHERAPY; PROCEDURES; SYNTHESIS; TREATMENT OUTCOME; TUMOR CELL LINE;

MUS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; FEMALE; HUMANS; IN VITRO TECHNIQUES; MICE; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; PERYLENE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; QUINONES; SCHIFF BASES; TREATMENT OUTCOME;

EID: 84901616398     PISSN: 15721000     EISSN: 18731597     Source Type: Journal    
DOI: 10.1016/j.pdpdt.2014.01.003     Document Type: Article

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