-
1
-
-
78650785470
-
The role of the breast cancer resistance protein (ABCG2) in the distribution of sorafenib to the brain
-
Agarwal S, Sane R, Ohlfest JR, Elmquist WF (2011) The role of the breast cancer resistance protein (ABCG2) in the distribution of sorafenib to the brain. J Pharmacol Exp Ther 336: 223.
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 223
-
-
Agarwal, S.1
Sane, R.2
Ohlfest, J.R.3
Elmquist, W.F.4
-
2
-
-
73349121946
-
Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases
-
Amaravadi RK, Schuchter LM, McDermott DF, Kramer A, Giles L, Gramlich K, Carberry M, Troxel AB, Letrero R, Nathanson KL, Atkins MB, O'Dwyer PJ, Flaherty KT (2009) Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases. Clin Cancer Res 15: 7711.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7711
-
-
Amaravadi, R.K.1
Schuchter, L.M.2
McDermott, D.F.3
Kramer, A.4
Giles, L.5
Gramlich, K.6
Carberry, M.7
Troxel, A.B.8
Letrero, R.9
Nathanson, K.L.10
Atkins, M.B.11
O'Dwyer, P.J.12
Flaherty, K.T.13
-
4
-
-
51049098909
-
Selected combination therapy with sorafenib: A review of clinical data and perspectives in advanced solid tumors
-
Dal Lago L, D'Hondt V, Awada A (2008) Selected combination therapy with sorafenib: a review of clinical data and perspectives in advanced solid tumors. Oncologist 13: 845.
-
(2008)
Oncologist
, vol.13
, pp. 845
-
-
Dal Lago, L.1
D'Hondt, V.2
Awada, A.3
-
5
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA (2002) Mutations of the BRAF gene in human cancer. Nature 417: 949.
-
(2002)
Nature
, vol.417
, pp. 949
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmieri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
6
-
-
84872198988
-
A phase i study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and rRecurrent high-grade gliomas
-
Den RB, Kamrava M, Sheng Z, Werner-Wasik M, Dougherty E, Marinucchi M, Lawrence YR, Hegarty S, Hyslop T, Andrews DW, Glass J, Friedman DP, Green MR, Camphausen K, Dicker AP (2012) A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and rRecurrent high-grade gliomas. Int J Radiat Oncol Biol Phys 85: 321-328.
-
(2012)
Int J Radiat Oncol Biol Phys
, vol.85
, pp. 321-328
-
-
Den Kamrava, R.B.M.1
Sheng, Z.2
Werner-Wasik, M.3
Dougherty, E.4
Marinucchi, M.5
Lawrence, Y.R.6
Hegarty, S.7
Hyslop, T.8
Andrews, D.W.9
Glass, J.10
Friedman, D.P.11
Green, M.R.12
Camphausen, K.13
Dicker, A.P.14
-
7
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, Negrier S, Chevreau C, Solska E, Desai AA, Rolland F, Demkow T, Hutson TE, Gore M, Freeman S, Schwartz B, Shan M, Simantov R, Bukowski RM (2007) Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356: 125.
-
(2007)
N Engl J Med
, vol.356
, pp. 125
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
8
-
-
77955363593
-
Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme
-
Hainsworth JD, Ervin T, Friedman E, Priego V, Murphy PB, Clark BL, Lamar RE (2010) Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. Cancer 116: 3663.
-
(2010)
Cancer
, vol.116
, pp. 3663
-
-
Hainsworth, J.D.1
Ervin, T.2
Friedman, E.3
Priego, V.4
Murphy, P.B.5
Clark, B.L.6
Lamar, R.E.7
-
9
-
-
84859628071
-
Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma
-
Hainsworth JD, Shih KC, Shepard GC, Tillinghast GW, Brinker BT, Spigel DR (2012) Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma. Clin Adv Hematol Oncol 10: 240.
-
(2012)
Clin Adv Hematol Oncol
, vol.10
, pp. 240
-
-
Hainsworth, J.D.1
Shih, K.C.2
Shepard, G.C.3
Tillinghast, G.W.4
Brinker, B.T.5
Spigel, D.R.6
-
10
-
-
0026772431
-
Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
-
Hermanson M, Funa K, Hartman M, Claesson-Welsh L, Heldin CH, Westermark B, Nister M (1992) Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res 52: 3213.
-
(1992)
Cancer Res
, vol.52
, pp. 3213
-
-
Hermanson, M.1
Funa, K.2
Hartman, M.3
Claesson-Welsh, L.4
Heldin, C.H.5
Westermark, B.6
Nister, M.7
-
11
-
-
34547453935
-
Characterization of the amplicon on chromosomal segment 4q12 in glioblastoma multiforme
-
Holtkamp N, Ziegenhagen N, Malzer E, Hartmann C, Giese A, von Deimling A (2007) Characterization of the amplicon on chromosomal segment 4q12 in glioblastoma multiforme. Neuro Oncol 9: 291.
-
(2007)
Neuro Oncol
, vol.9
, pp. 291
-
-
Holtkamp, N.1
Ziegenhagen, N.2
Malzer, E.3
Hartmann, C.4
Giese, A.5
Von Deimling, A.6
-
12
-
-
26044467362
-
Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme
-
Joensuu H, Puputti M, Sihto H, Tynninen O, Nupponen NN (2005) Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme. J Pathol 207: 224.
-
(2005)
J Pathol
, vol.207
, pp. 224
-
-
Joensuu, H.1
Puputti, M.2
Sihto, H.3
Tynninen, O.4
Nupponen, N.N.5
-
13
-
-
33846260566
-
Sorafenib for the treatment of advanced renal cell carcinoma
-
Kane RC, Farrell AT, Saber H, Tang S, Williams G, Jee JM, Liang C, Booth B, Chidambaram N, Morse D, Sridhara R, Garvey P, Justice R, Pazdur R (2006) Sorafenib for the treatment of advanced renal cell carcinoma. Clin Cancer Res 12: 7271.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7271
-
-
Kane, R.C.1
Farrell, A.T.2
Saber, H.3
Tang, S.4
Williams, G.5
Jee, J.M.6
Liang, C.7
Booth, B.8
Chidambaram, N.9
Morse, D.10
Sridhara, R.11
Garvey, P.12
Justice, R.13
Pazdur, R.14
-
14
-
-
79951984402
-
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
-
Lai A, Tran A, Nghiemphu PL, Pope WB, Solis OE, Selch M, Filka E, Yong WH, Mischel PS, Liau LM, Phuphanich S, Black K, Peak S, Green RM, Spier CE, Kolevska T, Polikoff J, Fehrenbacher L, Elashoff R, Cloughesy T (2011) Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol 29: 142.
-
(2011)
J Clin Oncol
, vol.29
, pp. 142
-
-
Lai, A.1
Tran, A.2
Nghiemphu, P.L.3
Pope, W.B.4
Solis, O.E.5
Selch, M.6
Filka, E.7
Yong, W.H.8
Mischel, P.S.9
Liau, L.M.10
Phuphanich, S.11
Black, K.12
Peak, S.13
Green, R.M.14
Spier, C.E.15
Kolevska, T.16
Polikoff, J.17
Fehrenbacher, L.18
Elashoff, R.19
Cloughesy, T.20
more..
-
15
-
-
66849118694
-
Dose escalation methods in phase i cancer clinical trials
-
Le Tourneau C, Lee JJ, Siu LL (2009) Dose escalation methods in phase I cancer clinical trials. J Natl Cancer Inst 101: 708.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 708
-
-
Le Tourneau, C.1
Lee, J.J.2
Siu, L.L.3
-
16
-
-
84869188311
-
Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02
-
Lee EQ, Kuhn J, Lamborn KR, Abrey L, Deangelis LM, Lieberman F, Robins HI, Chang SM, YungWK, Drappatz J, MehtaMP, LevinVA, Aldape K, Dancey JE, Wright JJ, Prados MD, Cloughesy TF, Gilbert MR, Wen PY (2012) Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02. Neuro Oncol 14: 1511-1518.
-
(2012)
Neuro Oncol
, vol.14
, pp. 1511-1518
-
-
Lee, E.Q.1
Kuhn, J.2
Lamborn, K.R.3
Abrey, L.4
Deangelis, L.M.5
Lieberman, F.6
Robins, H.I.7
Chang, S.M.8
Yung, W.K.9
Drappatz, J.10
Mehta, M.P.11
Levin, V.A.12
Aldape, K.13
Dancey, J.E.14
Wright, J.J.15
Prados, M.D.16
Cloughesy, T.F.17
Gilbert, M.R.18
Wen, P.Y.19
-
17
-
-
33846212284
-
Sorafenib blocks the RAF/MEK/ERK pathway inhibits tumor angiogenesis and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
-
Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, Wilhelm S, Lynch M, Carter C (2006) Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res 66: 11851.
-
(2006)
Cancer Res
, vol.66
, pp. 11851
-
-
Liu, L.1
Cao, Y.2
Chen, C.3
Zhang, X.4
McNabola, A.5
Wilkie, D.6
Wilhelm, S.7
Lynch, M.8
Carter, C.9
-
18
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, Schwartz M, Porta C, Zeuzem S, Bolondi L, Greten TF, Galle PR, Seitz JF, Borbath I, Haussinger D, Giannaris T, Shan M, Moscovici M, Voliotis D, Bruix J (2008) Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359: 378.
-
(2008)
N Engl J Med
, vol.359
, pp. 378
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
De Oliveira, A.C.7
Santoro, A.8
Raoul, J.L.9
Forner, A.10
Schwartz, M.11
Porta, C.12
Zeuzem, S.13
Bolondi, L.14
Greten, T.F.15
Galle, P.R.16
Seitz, J.F.17
Borbath, I.18
Haussinger, D.19
Giannaris, T.20
Shan, M.21
Moscovici, M.22
Voliotis, D.23
Bruix, J.24
more..
-
19
-
-
84863754907
-
VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
-
Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G (2012) VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell 22: 21.
-
(2012)
Cancer Cell
, vol.22
, pp. 21
-
-
Lu, K.V.1
Chang, J.P.2
Parachoniak, C.A.3
Pandika, M.M.4
Aghi, M.K.5
Meyronet, D.6
Isachenko, N.7
Fouse, S.D.8
Phillips, J.J.9
Cheresh, D.A.10
Park, M.11
Bergers, G.12
-
20
-
-
70249091030
-
Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas
-
Martinho O, Longatto-Filho A, Lambros MB, Martins A, Pinheiro C, Silva A, Pardal F, Amorim J, Mackay A, Milanezi F, Tamber N, Fenwick K, Ashworth A, Reis-Filho JS, Lopes JM, Reis RM (2009) Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. Br J Cancer 101: 973.
-
(2009)
Br J Cancer
, vol.101
, pp. 973
-
-
Martinho, O.1
Longatto-Filho, A.2
Lambros, M.B.3
Martins, A.4
Pinheiro, C.5
Silva, A.6
Pardal, F.7
Amorim, J.8
MacKay, A.9
Milanezi, F.10
Tamber, N.11
Fenwick, K.12
Ashworth, A.13
Reis-Filho, J.S.14
Lopes, J.M.15
Reis, R.M.16
-
21
-
-
35148842941
-
Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation
-
Plastaras JP, Kim SH, Liu YY, Dicker DT, Dorsey JF, McDonough J, Cerniglia G, Rajendran RR, Gupta A, Rustgi AK, Diehl JA, Smith CD, Flaherty KT, El-Deiry WS (2007) Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation. Cancer Res 67: 9443.
-
(2007)
Cancer Res
, vol.67
, pp. 9443
-
-
Plastaras, J.P.1
Kim, S.H.2
Liu, Y.Y.3
Dicker, D.T.4
Dorsey, J.F.5
McDonough, J.6
Cerniglia, G.7
Rajendran, R.R.8
Gupta, A.9
Rustgi, A.K.10
Diehl, J.A.11
Smith, C.D.12
Flaherty, K.T.13
El-Deiry, W.S.14
-
22
-
-
33846292596
-
Amplification of KIT, PDGFRA, VEGFR2, and EGFR in gliomas
-
Puputti M, Tynninen O, Sihto H, Blom T, Maenpaa H, Isola J, Paetau A, Joensuu H, Nupponen NN (2006) Amplification of KIT, PDGFRA, VEGFR2, and EGFR in gliomas. Mol Cancer Res 4: 927.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 927
-
-
Puputti, M.1
Tynninen, O.2
Sihto, H.3
Blom, T.4
Maenpaa, H.5
Isola, J.6
Paetau, A.7
Joensuu, H.8
Nupponen, N.N.9
-
23
-
-
79751535045
-
Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: Results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma
-
Reardon DA, Vredenburgh JJ, Desjardins A, Peters K, Gururangan S, Sampson JH, Marcello J, Herndon JEn, McLendon RE, Janney D, Friedman AH, Bigner DD, Friedman HS (2011) Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. J Neurooncol 101: 57.
-
(2011)
J Neurooncol
, vol.101
, pp. 57
-
-
Reardon, D.A.1
Vredenburgh, J.J.2
Desjardins, A.3
Peters, K.4
Gururangan, S.5
Sampson, J.H.6
Marcello, J.7
Herndon, J.E.N.8
McLendon, R.E.9
Janney, D.10
Friedman, A.H.11
Bigner, D.D.12
Friedman, H.S.13
-
24
-
-
0038737156
-
Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma
-
Salmaggi A, Eoli M, Frigerio S, Silvani A, Gelati M, Corsini E, Broggi G, Boiardi A (2003) Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma. J Neurooncol 62: 297.
-
(2003)
J Neurooncol
, vol.62
, pp. 297
-
-
Salmaggi, A.1
Eoli, M.2
Frigerio, S.3
Silvani, A.4
Gelati, M.5
Corsini, E.6
Broggi, G.7
Boiardi, A.8
-
25
-
-
3142713010
-
Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis
-
Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC (2004) Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res 64: 4783.
-
(2004)
Cancer Res
, vol.64
, pp. 4783
-
-
Shih, A.H.1
Dai, C.2
Hu, X.3
Rosenblum, M.K.4
Koutcher, J.A.5
Holland, E.C.6
-
26
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987.
-
(2005)
N Engl J Med
, vol.352
, pp. 987
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
27
-
-
48249112123
-
Incidence of early pseudo-progression in a cohort of malignant glioma patients treated with chemoirradiation with temozolomide
-
Taal W, Brandsma D, de Bruin HG, Bromberg JE, Swaak-Kragten AT, Smitt PA, van Es CA, van den Bent MJ (2008) Incidence of early pseudo-progression in a cohort of malignant glioma patients treated with chemoirradiation with temozolomide. Cancer 113: 405.
-
(2008)
Cancer
, vol.113
, pp. 405
-
-
Taal, W.1
Brandsma, D.2
De Bruin, H.G.3
Bromberg, J.E.4
Swaak-Kragten, A.T.5
Smitt, P.A.6
Van Es, C.A.7
Van Den Bent, M.J.8
-
28
-
-
47649131468
-
Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma
-
Vlassenbroeck I, Califice S, Diserens AC, Migliavacca E, Straub J, Di Stefano I, Moreau F, Hamou MF, Renard I, Delorenzi M, Flamion B, DiGuiseppi J, Bierau K, Hegi ME (2008) Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma. J Mol Diagn 10: 332.
-
(2008)
J Mol Diagn
, vol.10
, pp. 332
-
-
Vlassenbroeck, I.1
Califice, S.2
Diserens, A.C.3
Migliavacca, E.4
Straub, J.5
Di Stefano, I.6
Moreau, F.7
Hamou, M.F.8
Renard, I.9
Delorenzi, M.10
Flamion, B.11
Diguiseppi, J.12
Bierau, K.13
Hegi, M.E.14
-
29
-
-
83955165997
-
Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme
-
Vredenburgh JJ, Desjardins A, Kirkpatrick JP, Reardon DA, Peters KB, Herndon JEn, Marcello J, Bailey L, Threatt S, Sampson J, Friedman A, Friedman HS (2012) Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys 82: 58.
-
(2012)
Int J Radiat Oncol Biol Phys
, vol.82
, pp. 58
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Kirkpatrick, J.P.3
Reardon, D.A.4
Peters, K.B.5
Herndon, J.E.N.6
Marcello, J.7
Bailey, L.8
Threatt, S.9
Sampson, J.10
Friedman, A.11
Friedman, H.S.12
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-
-
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-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
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Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA (2004) BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 64: 7099.
-
(2004)
Cancer Res
, vol.64
, pp. 7099
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
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