-
1
-
-
80054988878
-
The influence of physical properties and morphology of crystallised lactose on delivery of salbutamol sulphate from dry powder inhalers
-
W. Kaialy et al. The influence of physical properties and morphology of crystallised lactose on delivery of salbutamol sulphate from dry powder inhalers Colloids Surf. B: Biointerfaces 89 2011 29 39
-
(2011)
Colloids Surf. B: Biointerfaces
, vol.89
, pp. 29-39
-
-
Kaialy, W.1
-
2
-
-
84865406808
-
Antisolvent crystallisation is a potential technique to prepare engineered lactose with promising aerosolisation properties: Effect of saturation degree
-
W. Kaialy, and A. Nokhodchi Antisolvent crystallisation is a potential technique to prepare engineered lactose with promising aerosolisation properties: effect of saturation degree Int. J. Pharm. 437 2012 57 69
-
(2012)
Int. J. Pharm.
, vol.437
, pp. 57-69
-
-
Kaialy, W.1
Nokhodchi, A.2
-
3
-
-
79951988746
-
Characterisation and deposition studies of recrystallised lactose from binary mixtures of ethanol/butanol for improved drug delivery from dry powder inhalers
-
W. Kaialy et al. Characterisation and deposition studies of recrystallised lactose from binary mixtures of ethanol/butanol for improved drug delivery from dry powder inhalers AAPS J. 13 2011 30 43
-
(2011)
AAPS J.
, vol.13
, pp. 30-43
-
-
Kaialy, W.1
-
4
-
-
84856517911
-
Dry powder inhalers: Mechanistic evaluation of lactose formulations containing salbutamol sulphate
-
W. Kaialy et al. Dry powder inhalers: mechanistic evaluation of lactose formulations containing salbutamol sulphate Int. J. Pharm. 423 2011 184 194
-
(2011)
Int. J. Pharm.
, vol.423
, pp. 184-194
-
-
Kaialy, W.1
-
5
-
-
79955613972
-
Improved aerosolization performance of salbutamol sulfate formulated with lactose crystallized from binary mixtures of ethanol - Acetone
-
W. Kaialy et al. Improved aerosolization performance of salbutamol sulfate formulated with lactose crystallized from binary mixtures of ethanol - acetone J. Pharm. Sci. 100 2011 2665 2684
-
(2011)
J. Pharm. Sci.
, vol.100
, pp. 2665-2684
-
-
Kaialy, W.1
-
6
-
-
0026572056
-
Pulmonary delivery of peptides and proteins for systemic action
-
J.S. Patton, and R.M. Platz Pulmonary delivery of peptides and proteins for systemic action Adv. Drug Deliv. Rev. 8 1992 179 228
-
(1992)
Adv. Drug Deliv. Rev.
, vol.8
, pp. 179-228
-
-
Patton, J.S.1
Platz, R.M.2
-
7
-
-
84875912337
-
Lactose engineering for better performance in dry powder inhalers
-
Y. Rahimpour, and H. Hamishehkar Lactose engineering for better performance in dry powder inhalers Adv. Pharm. Bull. 2 2012 183 187
-
(2012)
Adv. Pharm. Bull.
, vol.2
, pp. 183-187
-
-
Rahimpour, Y.1
Hamishehkar, H.2
-
9
-
-
34347388526
-
Alternatives for the lactose-intolerant patient
-
A. Glasnapp Alternatives for the lactose-intolerant patient Int. J. Pharm. Compd. 2 1998 412 413
-
(1998)
Int. J. Pharm. Compd.
, vol.2
, pp. 412-413
-
-
Glasnapp, A.1
-
10
-
-
77349091988
-
Effect of carrier morphology and surface characteristics on the development of respirable PLGA microcapsules for sustained-release pulmonary delivery of insulin
-
H. Hamishehkar et al. Effect of carrier morphology and surface characteristics on the development of respirable PLGA microcapsules for sustained-release pulmonary delivery of insulin Int. J. Pharm. 389 2010 74 85
-
(2010)
Int. J. Pharm.
, vol.389
, pp. 74-85
-
-
Hamishehkar, H.1
-
11
-
-
77951089296
-
Pharmacokinetics and pharmacodynamics of controlled release insulin loaded PLGA microcapsules using dry powder inhaler in diabetic rats
-
H. Hamishehkar et al. Pharmacokinetics and pharmacodynamics of controlled release insulin loaded PLGA microcapsules using dry powder inhaler in diabetic rats Biopharm. Drug. Dispos. 31 2010 189 201
-
(2010)
Biopharm. Drug. Dispos.
, vol.31
, pp. 189-201
-
-
Hamishehkar, H.1
-
12
-
-
0035806263
-
Effect of additives on insulin absorption from intratracheally administered dry powders in rats
-
H. Todo et al. Effect of additives on insulin absorption from intratracheally administered dry powders in rats Int. J. Pharm. 220 2001 101 110
-
(2001)
Int. J. Pharm.
, vol.220
, pp. 101-110
-
-
Todo, H.1
-
13
-
-
0030770631
-
Rational design of stable lyophilized protein formulations: Some practical advice
-
J.F. Carpenter et al. Rational design of stable lyophilized protein formulations: some practical advice Pharm. Res. 14 1997 969 975
-
(1997)
Pharm. Res.
, vol.14
, pp. 969-975
-
-
Carpenter, J.F.1
-
14
-
-
0031560902
-
Review of dry powder inhalers
-
D. Prime et al. Review of dry powder inhalers Adv. Drug Deliv. Rev. 26 1997 51 58
-
(1997)
Adv. Drug Deliv. Rev.
, vol.26
, pp. 51-58
-
-
Prime, D.1
-
15
-
-
77953357611
-
Influence of carrier particle size, carrier ratio and addition of fine ternary particles on the dry powder inhalation performance of insulin-loaded PLGA microcapsules
-
H. Hamishehkar et al. Influence of carrier particle size, carrier ratio and addition of fine ternary particles on the dry powder inhalation performance of insulin-loaded PLGA microcapsules Powder Technol. 201 2010 289 295
-
(2010)
Powder Technol.
, vol.201
, pp. 289-295
-
-
Hamishehkar, H.1
-
16
-
-
3142736767
-
Effect of surface covering of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate
-
K. Iida et al. Effect of surface covering of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate Chem. Pharm. Bull. 51 2003 1455 1457
-
(2003)
Chem. Pharm. Bull.
, vol.51
, pp. 1455-1457
-
-
Iida, K.1
-
17
-
-
3543128402
-
Evaluation of SCF-engineered particle-based lactose blends in passive dry powder inhalers
-
H. Schiavone et al. Evaluation of SCF-engineered particle-based lactose blends in passive dry powder inhalers Int. J. Pharm. 281 2004 55 66
-
(2004)
Int. J. Pharm.
, vol.281
, pp. 55-66
-
-
Schiavone, H.1
-
18
-
-
33645892558
-
Preparation and in vitro evaluation of lipidic carriers and fillers for inhalation
-
T. Sebti, and K. Amighi Preparation and in vitro evaluation of lipidic carriers and fillers for inhalation Eur. J. Pharm. Biopharm. 63 2006 51 58
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.63
, pp. 51-58
-
-
Sebti, T.1
Amighi, K.2
-
19
-
-
84858624234
-
Lactose characteristics and the generation of the aerosol
-
G. Pilcer et al. Lactose characteristics and the generation of the aerosol Adv. Drug Deliv. Rev. 64 2012 233 256
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 233-256
-
-
Pilcer, G.1
-
21
-
-
33644617924
-
Dry powder inhaler formulation
-
M.J. Telko, and A.J. Hickey Dry powder inhaler formulation Resp. Care 50 2005 1209 1227
-
(2005)
Resp. Care
, vol.50
, pp. 1209-1227
-
-
Telko, M.J.1
Hickey, A.J.2
-
22
-
-
2342587533
-
Pressure and inspiratory flow characteristics of dry powder inhalers
-
U.H. Cegla Pressure and inspiratory flow characteristics of dry powder inhalers Respir. Med. 98 2004 S22 S28
-
(2004)
Respir. Med.
, vol.98
-
-
Cegla, U.H.1
-
23
-
-
0033661914
-
A comparison of dry powder inhaler dose delivery characteristics using a power criterion
-
C.A. Dunbar et al. A comparison of dry powder inhaler dose delivery characteristics using a power criterion PDA. J. Pharm. Sci. Technol. 54 2000 478 484
-
(2000)
PDA. J. Pharm. Sci. Technol.
, vol.54
, pp. 478-484
-
-
Dunbar, C.A.1
-
25
-
-
0342657112
-
The influence of carrier morphology on drug delivery by dry powder inhalers
-
X.M. Zeng et al. The influence of carrier morphology on drug delivery by dry powder inhalers Int. J. Pharm. 200 2000 93 106
-
(2000)
Int. J. Pharm.
, vol.200
, pp. 93-106
-
-
Zeng, X.M.1
-
26
-
-
0343485036
-
The inuence of lactose carrier on the content homogeneity and dispersibility of beclomethasone dipropionate from dry powder aerosols
-
X.M. Zeng et al. The inuence of lactose carrier on the content homogeneity and dispersibility of beclomethasone dipropionate from dry powder aerosols Int. J. Pharm. 197 2000 41 52
-
(2000)
Int. J. Pharm.
, vol.197
, pp. 41-52
-
-
Zeng, X.M.1
-
27
-
-
84876698504
-
Investigation into alternative sugars as potential carriers for dry powder formulation of budesonide
-
M.-N. Momin et al. Investigation into alternative sugars as potential carriers for dry powder formulation of budesonide BioImpacts 1 2011 105 111
-
(2011)
BioImpacts
, vol.1
, pp. 105-111
-
-
Momin, M.-N.1
-
29
-
-
0347021194
-
Alternative sugars as potential carriers for dry powder inhalations
-
H. Steckel, and N. Bolzen Alternative sugars as potential carriers for dry powder inhalations Int. J. Pharm. 270 2004 297 306
-
(2004)
Int. J. Pharm.
, vol.270
, pp. 297-306
-
-
Steckel, H.1
Bolzen, N.2
-
30
-
-
33947109116
-
Influence of carrier on the performance of dry powder inhalers
-
G. Saint-Lorant et al. Influence of carrier on the performance of dry powder inhalers Int. J. Pharm. 334 2007 85 91
-
(2007)
Int. J. Pharm.
, vol.334
, pp. 85-91
-
-
Saint-Lorant, G.1
-
31
-
-
77952742519
-
The enhanced aerosol performance of salbutamol from dry powders containing engineered mannitol as excipient
-
W. Kaialy et al. The enhanced aerosol performance of salbutamol from dry powders containing engineered mannitol as excipient Int. J. Pharm. 392 2010 178 188
-
(2010)
Int. J. Pharm.
, vol.392
, pp. 178-188
-
-
Kaialy, W.1
-
32
-
-
77955097507
-
Dry powder aerosols generated by standardized entrainment tubes from alternative sugar blends: 3. Trehalose dihydrate and d-mannitol carriers
-
H.M. Mansour et al. Dry powder aerosols generated by standardized entrainment tubes from alternative sugar blends: 3. Trehalose dihydrate and d-mannitol carriers J. Pharm. Sci. 99 2010 3430 3441
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 3430-3441
-
-
Mansour, H.M.1
-
33
-
-
58249107940
-
Characterisation and aerosolisation of mannitol particles produced via confined liquid impinging jets
-
P. Tang et al. Characterisation and aerosolisation of mannitol particles produced via confined liquid impinging jets Int. J. Pharm. 367 2009 51 57
-
(2009)
Int. J. Pharm.
, vol.367
, pp. 51-57
-
-
Tang, P.1
-
34
-
-
77953021975
-
Co-spray-dried mannitol-ciprooxacin dry powder inhaler formulation for cystic brosis and chronic obstructive pulmonary disease
-
H. Adi et al. Co-spray-dried mannitol-ciprooxacin dry powder inhaler formulation for cystic brosis and chronic obstructive pulmonary disease Eur. J. Pharm. Sci. 40 2010 239 247
-
(2010)
Eur. J. Pharm. Sci.
, vol.40
, pp. 239-247
-
-
Adi, H.1
-
35
-
-
84866021699
-
Spray dried mannitol carrier particles with tailored surface properties - The influence of carrier surface roughness and shape
-
E.M. Littringer et al. Spray dried mannitol carrier particles with tailored surface properties - the influence of carrier surface roughness and shape Eur. J. Pharm. Biopharm. 82 2012 194 204
-
(2012)
Eur. J. Pharm. Biopharm.
, vol.82
, pp. 194-204
-
-
Littringer, E.M.1
-
36
-
-
81155122980
-
Effect of carrier particle shape on dry powder inhaler performance
-
W. Kaialy et al. Effect of carrier particle shape on dry powder inhaler performance Int. J. Pharm. 421 2011 12 23
-
(2011)
Int. J. Pharm.
, vol.421
, pp. 12-23
-
-
Kaialy, W.1
-
37
-
-
0042383327
-
Effects of carriers and storage of formulation on the lung deposition of a hydrophobic and hydrophilic drug from a DPI
-
P. Harjunen et al. Effects of carriers and storage of formulation on the lung deposition of a hydrophobic and hydrophilic drug from a DPI Int. J. Pharm. 263 2003 151 163
-
(2003)
Int. J. Pharm.
, vol.263
, pp. 151-163
-
-
Harjunen, P.1
-
38
-
-
77953915537
-
Engineered mannitol as an alternative carrier to enhance deep lung penetration of salbutamol sulphate from dry powder inhaler
-
W. Kaialy et al. Engineered mannitol as an alternative carrier to enhance deep lung penetration of salbutamol sulphate from dry powder inhaler Colloids Surf. B: Biointerfaces 79 2010 345 356
-
(2010)
Colloids Surf. B: Biointerfaces
, vol.79
, pp. 345-356
-
-
Kaialy, W.1
-
39
-
-
84873475700
-
Freeze-dried mannitol for superior pulmonary drug delivery via dry powder inhaler
-
W. Kaialy, and A. Nokhodchi Freeze-dried mannitol for superior pulmonary drug delivery via dry powder inhaler Pharm. Res. 30 2013 458 477
-
(2013)
Pharm. Res.
, vol.30
, pp. 458-477
-
-
Kaialy, W.1
Nokhodchi, A.2
-
40
-
-
84875684659
-
Treating mannitol in a saturated solution of mannitol: A novel approach to modify mannitol crystals for improved drug delivery to the lungs
-
W. Kaialy, and A. Nokhodchi Treating mannitol in a saturated solution of mannitol: a novel approach to modify mannitol crystals for improved drug delivery to the lungs Int. J. Pharm. 448 2013 58 70
-
(2013)
Int. J. Pharm.
, vol.448
, pp. 58-70
-
-
Kaialy, W.1
Nokhodchi, A.2
-
41
-
-
84864490841
-
The effect of engineered mannitol-lactose mixture on dry powder inhaler performance
-
W. Kaialy et al. The effect of engineered mannitol-lactose mixture on dry powder inhaler performance Pharm. Res. 29 2012 2139 2156
-
(2012)
Pharm. Res.
, vol.29
, pp. 2139-2156
-
-
Kaialy, W.1
-
42
-
-
37849013359
-
Composite carriers improve the aerosolisation efficiency of drugs for respiratory delivery
-
P.M. Young et al. Composite carriers improve the aerosolisation efficiency of drugs for respiratory delivery J. Aerosol. Sci. 39 2008 82 93
-
(2008)
J. Aerosol. Sci.
, vol.39
, pp. 82-93
-
-
Young, P.M.1
-
43
-
-
84881369362
-
Effect of polymers for aerolisation properties of mannitol based microcomposites containing meloxicam
-
A. Pomázi et al. Effect of polymers for aerolisation properties of mannitol based microcomposites containing meloxicam Eur. Polym. J. 49 2013 2518 2527
-
(2013)
Eur. Polym. J.
, vol.49
, pp. 2518-2527
-
-
Pomázi, A.1
-
44
-
-
4644330189
-
Aerosolization properties, surface composition and physical state of spray-dried protein powders
-
C. Bosquillon et al. Aerosolization properties, surface composition and physical state of spray-dried protein powders J. Control. Release 99 2004 357 367
-
(2004)
J. Control. Release
, vol.99
, pp. 357-367
-
-
Bosquillon, C.1
-
45
-
-
48149093621
-
Stabilization of IgG1 in spray-dried powders for inhalation
-
S. Schüle et al. Stabilization of IgG1 in spray-dried powders for inhalation Eur. J. Pharm. Biopharm. 69 2008 793
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.69
, pp. 793
-
-
Schüle, S.1
-
46
-
-
36649033018
-
Conformational analysis of protein secondary structure during spray-drying of antibody/mannitol formulations
-
S. Schüle et al. Conformational analysis of protein secondary structure during spray-drying of antibody/mannitol formulations Eur. J. Pharm. Biopharm. 65 2007 1 9
-
(2007)
Eur. J. Pharm. Biopharm.
, vol.65
, pp. 1-9
-
-
Schüle, S.1
-
47
-
-
39649088233
-
Do co-spray dried excipients offer better lysozyme stabilisation than single excipients?
-
W.L. Hulse et al. Do co-spray dried excipients offer better lysozyme stabilisation than single excipients? Eur. J. Pharm. Sci. 33 2008 294 305
-
(2008)
Eur. J. Pharm. Sci.
, vol.33
, pp. 294-305
-
-
Hulse, W.L.1
-
48
-
-
84881365375
-
The effects of mannitol on the transport of ciprofloxacin across respiratory epithelia
-
H.X. Ong et al. The effects of mannitol on the transport of ciprofloxacin across respiratory epithelia Mol. Pharmaceut. 10 2013 2915 2924
-
(2013)
Mol. Pharmaceut.
, vol.10
, pp. 2915-2924
-
-
Ong, H.X.1
-
49
-
-
0036746761
-
Predicting the quality of powders for inhalation from surface energy and area
-
D. Cline, and R. Dalby Predicting the quality of powders for inhalation from surface energy and area Pharm. Res. 19 2002 1274 1277
-
(2002)
Pharm. Res.
, vol.19
, pp. 1274-1277
-
-
Cline, D.1
Dalby, R.2
-
50
-
-
83555173327
-
Physicochemical characterization and water vapor sorption of organic solution advanced spray-dried inhalable trehalose microparticles and nanoparticles for targeted dry powder pulmonary inhalation delivery
-
X. Li, and H.M. Mansour Physicochemical characterization and water vapor sorption of organic solution advanced spray-dried inhalable trehalose microparticles and nanoparticles for targeted dry powder pulmonary inhalation delivery AAPS PharmSciTech 12 2011 1420 1430
-
(2011)
AAPS PharmSciTech
, vol.12
, pp. 1420-1430
-
-
Li, X.1
Mansour, H.M.2
-
51
-
-
84873706384
-
The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules
-
T. Sou et al. The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules Eur. J. Pharm. Biopharm. 83 2013 234 243
-
(2013)
Eur. J. Pharm. Biopharm.
, vol.83
, pp. 234-243
-
-
Sou, T.1
-
52
-
-
76549105967
-
Erythritol: Crystal growth from the melt
-
J.A.J. Lopes et al. Erythritol: crystal growth from the melt Int. J. Pharm. 388 2010 129 135
-
(2010)
Int. J. Pharm.
, vol.388
, pp. 129-135
-
-
Lopes, J.A.J.1
-
53
-
-
0000633659
-
Water sorption, binding and solubility of polyols
-
S. Cohen et al. Water sorption, binding and solubility of polyols J. Chem. Soc., Faraday Trans. 89 1993 3271 3275
-
(1993)
J. Chem. Soc., Faraday Trans.
, vol.89
, pp. 3271-3275
-
-
Cohen, S.1
-
54
-
-
0032411028
-
Erythritol: An interpretive summary of biochemical, metabolic, toxicological and clinical data
-
I.C. Munro et al. Erythritol: an interpretive summary of biochemical, metabolic, toxicological and clinical data Food Chem. Toxicol. 36 1998 1139 1174
-
(1998)
Food Chem. Toxicol.
, vol.36
, pp. 1139-1174
-
-
Munro, I.C.1
-
55
-
-
12344276697
-
Erythritol-based dry powder of glucagon for pulmonary administration
-
K. Endo et al. Erythritol-based dry powder of glucagon for pulmonary administration Int. J. Pharm. 290 2005 63 71
-
(2005)
Int. J. Pharm.
, vol.290
, pp. 63-71
-
-
Endo, K.1
-
56
-
-
34250846491
-
Development of directly compressible powders via co-spray drying
-
Y. Gonnissen et al. Development of directly compressible powders via co-spray drying Eur. J. Pharm. Biopharm. 67 2007 220 226
-
(2007)
Eur. J. Pharm. Biopharm.
, vol.67
, pp. 220-226
-
-
Gonnissen, Y.1
-
57
-
-
29244473532
-
Comparative study of erythritol and lactose monohydrate as carriers for inhalation: Atomic force microscopy and in vitro correlation
-
D. Traini et al. Comparative study of erythritol and lactose monohydrate as carriers for inhalation: atomic force microscopy and in vitro correlation Eur. J. Pharm. Sci. 27 2006 243 251
-
(2006)
Eur. J. Pharm. Sci.
, vol.27
, pp. 243-251
-
-
Traini, D.1
-
58
-
-
0029781099
-
Effects of reducing sugars on the chemical stability of human relaxin in the lyophilized state
-
S. Li et al. Effects of reducing sugars on the chemical stability of human relaxin in the lyophilized state J. Pharm. Sci. 85 1996 873 877
-
(1996)
J. Pharm. Sci.
, vol.85
, pp. 873-877
-
-
Li, S.1
-
59
-
-
0030445828
-
Characterization of a solid state reaction product from a lyophilized formulation of a cyclic heptapeptide: A novel example of an excipient-induced oxidation
-
D.C. Dubost et al. Characterization of a solid state reaction product from a lyophilized formulation of a cyclic heptapeptide: a novel example of an excipient-induced oxidation Pharm. Res. 13 1996 1811 1814
-
(1996)
Pharm. Res.
, vol.13
, pp. 1811-1814
-
-
Dubost, D.C.1
-
60
-
-
21744457648
-
Carrier-based strategies for targeting protein and peptide drugs to the lungs
-
S.A. Cryan Carrier-based strategies for targeting protein and peptide drugs to the lungs AAPS J. 7 2005 20 41
-
(2005)
AAPS J.
, vol.7
, pp. 20-41
-
-
Cryan, S.A.1
-
61
-
-
84901484005
-
Pharmaceutical aerosol formulation of solid polypeptide microparticles and method for the preparation thereof
-
R. Platz et al. Pharmaceutical aerosol formulation of solid polypeptide microparticles and method for the preparation thereof World Patent 9116038 1991
-
(1991)
World Patent 9116038
-
-
Platz, R.1
-
62
-
-
84882545671
-
Process for preparing micronized polypeptide drugs
-
R. Platz et al. Process for preparing micronized polypeptide drugs US Patent 5354562 1994
-
(1994)
US Patent 5354562
-
-
Platz, R.1
-
63
-
-
0034605690
-
The use of different sugars as fine and coarse carriers for aerosolised salbutamol sulphate
-
S.K. Tee et al. The use of different sugars as fine and coarse carriers for aerosolised salbutamol sulphate Int. J. Pharm. 208 2000 111 123
-
(2000)
Int. J. Pharm.
, vol.208
, pp. 111-123
-
-
Tee, S.K.1
-
64
-
-
76649096973
-
Feasibility study of pollen-shape drug carriers in dry powder inhalation
-
M.S. Hassan, and R. Lau Feasibility study of pollen-shape drug carriers in dry powder inhalation J. Pharm. Sci. 99 2010 1309 1321
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 1309-1321
-
-
Hassan, M.S.1
Lau, R.2
-
65
-
-
77952744763
-
Formulation strategy and use of excipients in pulmonary drug delivery
-
G. Pilcer, and K. Amighi Formulation strategy and use of excipients in pulmonary drug delivery Int. J. Pharm. 392 2010 1 19
-
(2010)
Int. J. Pharm.
, vol.392
, pp. 1-19
-
-
Pilcer, G.1
Amighi, K.2
-
66
-
-
79151477339
-
Particle engineering of materials for oral inhalation by dry powder inhalers. I. Particles of sugar excipients (trehalose and raffinose) for protein delivery
-
O.N. Ógáin et al. Particle engineering of materials for oral inhalation by dry powder inhalers. I. Particles of sugar excipients (trehalose and raffinose) for protein delivery Int. J. Pharm. 405 2011 23 35
-
(2011)
Int. J. Pharm.
, vol.405
, pp. 23-35
-
-
Ógáin, O.N.1
-
67
-
-
33847228348
-
Humidity-induced changes of the aerodynamic properties of dry powder aerosol formulations containing different carriers
-
X.M. Zeng et al. Humidity-induced changes of the aerodynamic properties of dry powder aerosol formulations containing different carriers Int. J. Pharm. 333 2007 45 55
-
(2007)
Int. J. Pharm.
, vol.333
, pp. 45-55
-
-
Zeng, X.M.1
-
68
-
-
34247569453
-
Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems
-
P.M. Young et al. Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems Pharm. Res. 24 2007 963 970
-
(2007)
Pharm. Res.
, vol.24
, pp. 963-970
-
-
Young, P.M.1
-
69
-
-
33745041254
-
Predicting the behavior of novel sugar carriers for dry powder inhaler formulations via the use of a cohesive-adhesive force balance approach
-
J.C. Hooton et al. Predicting the behavior of novel sugar carriers for dry powder inhaler formulations via the use of a cohesive-adhesive force balance approach J. Pharm. Sci. 95 2006 1288 1297
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 1288-1297
-
-
Hooton, J.C.1
-
70
-
-
84901493470
-
Pulmonary drug delivery using large, porous-hollow inhaled particles
-
D. Suraj et al. Pulmonary drug delivery using large, porous-hollow inhaled particles Int. J. Nat. Product Sci. 1 2012 35
-
(2012)
Int. J. Nat. Product Sci.
, vol.1
, pp. 35
-
-
Suraj, D.1
-
71
-
-
10744227569
-
Large porous particles for pulmonary drug delivery
-
D.A. Edwards et al. Large porous particles for pulmonary drug delivery Science 276 1997 1868 1871
-
(1997)
Science
, vol.276
, pp. 1868-1871
-
-
Edwards, D.A.1
-
72
-
-
1542511344
-
Preparation of large porous deslorelin-PLGA microparticles with reduced residual solvent and cellular uptake using a supercritical carbon dioxide process
-
K. Koushik, and U.B. Kompella Preparation of large porous deslorelin-PLGA microparticles with reduced residual solvent and cellular uptake using a supercritical carbon dioxide process Pharm. Res. 21 2004 524 535
-
(2004)
Pharm. Res.
, vol.21
, pp. 524-535
-
-
Koushik, K.1
Kompella, U.B.2
-
73
-
-
0032734092
-
Formulation and physical characterization of large porous particles for inhalation
-
R. Vanbever et al. Formulation and physical characterization of large porous particles for inhalation Pharm. Res. 16 1999 1735 1742
-
(1999)
Pharm. Res.
, vol.16
, pp. 1735-1742
-
-
Vanbever, R.1
-
74
-
-
0344943933
-
Pulmonary drug delivery. Part II: The role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications
-
N.R. Labiris, and M.B. Dolovich Pulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications Br. J. Clin. Pharmacol. 56 2003 600 612
-
(2003)
Br. J. Clin. Pharmacol.
, vol.56
, pp. 600-612
-
-
Labiris, N.R.1
Dolovich, M.B.2
-
75
-
-
0035998946
-
Factors affecting the deposition of inhaled porous drug particles
-
C.J. Musante et al. Factors affecting the deposition of inhaled porous drug particles J. Pharm. Sci. 91 2002 1590 1600
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 1590-1600
-
-
Musante, C.J.1
-
76
-
-
84877041363
-
Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose
-
D.S. Dhanda et al. Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose J. Control. Release 168 2013 239 250
-
(2013)
J. Control. Release
, vol.168
, pp. 239-250
-
-
Dhanda, D.S.1
-
77
-
-
84877256054
-
Inhaled PLGA particles of prostaglandin E1 ameliorate symptoms and progression of pulmonary hypertension at a reduced dosing frequency
-
V. Gupta et al. Inhaled PLGA particles of prostaglandin E1 ameliorate symptoms and progression of pulmonary hypertension at a reduced dosing frequency Mol. Pharm. 10 2013 1655 1667
-
(2013)
Mol. Pharm.
, vol.10
, pp. 1655-1667
-
-
Gupta, V.1
-
78
-
-
84865340746
-
PEG-PLGA based large porous particles for pulmonary delivery of a highly soluble drug, low molecular weight heparin
-
B. Patel et al. PEG-PLGA based large porous particles for pulmonary delivery of a highly soluble drug, low molecular weight heparin J. Control. Release 162 2012 310 320
-
(2012)
J. Control. Release
, vol.162
, pp. 310-320
-
-
Patel, B.1
-
79
-
-
61649125992
-
Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: In vivo deposition and hypoglycaemic activity after delivery to rat lungs
-
F. Ungaro et al. Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: in vivo deposition and hypoglycaemic activity after delivery to rat lungs J. Control. Release 135 2009 25 34
-
(2009)
J. Control. Release
, vol.135
, pp. 25-34
-
-
Ungaro, F.1
-
80
-
-
59649112391
-
Development of highly porous large PLGA microparticles for pulmonary drug delivery
-
Y. Yang et al. Development of highly porous large PLGA microparticles for pulmonary drug delivery Biomaterials 30 2009 1947 1953
-
(2009)
Biomaterials
, vol.30
, pp. 1947-1953
-
-
Yang, Y.1
-
81
-
-
44649138531
-
Inhalable large porous microspheres of low molecular weight hepar in vitro in vivo evaluation
-
A. Rawat et al. Inhalable large porous microspheres of low molecular weight hepar in vitro in vivo evaluation J. Control. Release 128 2008 224 232
-
(2008)
J. Control. Release
, vol.128
, pp. 224-232
-
-
Rawat, A.1
-
82
-
-
0032926859
-
Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs
-
A. Ben-Jebria et al. Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs Pharm. Res. 16 1999 555 561
-
(1999)
Pharm. Res.
, vol.16
, pp. 555-561
-
-
Ben-Jebria, A.1
-
83
-
-
84884168091
-
Formulation of pyrazinamide-loaded large porous particles for the pulmonary route: Avoiding crystal growth using excipients
-
D.-D. Pham et al. Formulation of pyrazinamide-loaded large porous particles for the pulmonary route: avoiding crystal growth using excipients Int. J. Pharm. 454 2013 668 677
-
(2013)
Int. J. Pharm.
, vol.454
, pp. 668-677
-
-
Pham, D.-D.1
-
84
-
-
34547642167
-
Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model
-
L. Garcia-Contreras et al. Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model Antimicrob. Agents Chemother. 51 2007 2830 2836
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 2830-2836
-
-
Garcia-Contreras, L.1
-
85
-
-
2442666256
-
A novel spray-drying technique to produce low density particles for pulmonary delivery
-
H. Steckel, and H.G. Brandes A novel spray-drying technique to produce low density particles for pulmonary delivery Int. J. Pharm. 278 2004 187 195
-
(2004)
Int. J. Pharm.
, vol.278
, pp. 187-195
-
-
Steckel, H.1
Brandes, H.G.2
-
86
-
-
10744225450
-
Direct lung delivery of para-aminosalicylic acid by aerosol particles
-
N. Tsapis et al. Direct lung delivery of para-aminosalicylic acid by aerosol particles Tuberculosis 83 2003 379 385
-
(2003)
Tuberculosis
, vol.83
, pp. 379-385
-
-
Tsapis, N.1
-
87
-
-
84901487253
-
Nanoparticles for pulmonary delivery
-
H.D.C. Smyth, A.J. Hickey, Springer New York
-
A.B. Watts, and R.O. Williams 3rd Nanoparticles for pulmonary delivery H.D.C. Smyth, A.J. Hickey, Controlled Pulmonary Drug Delivery 2011 Springer New York 335 366
-
(2011)
Controlled Pulmonary Drug Delivery
, pp. 335-366
-
-
Watts, A.B.1
Williams III, R.O.2
-
88
-
-
66949153801
-
Pharmacokinetics of ciprofloxacin PulmoSphere® inhalational powder
-
H. Stass et al. Pharmacokinetics of ciprofloxacin PulmoSphere® inhalational powder J. Cyst. Fibros. 7 2008 S26
-
(2008)
J. Cyst. Fibros.
, vol.7
, pp. 26
-
-
Stass, H.1
-
89
-
-
34247193128
-
Novel tobramycin inhalation powder in cystic brosis subjects: Pharmacokinetics and safety
-
D.E. Geller et al. Novel tobramycin inhalation powder in cystic brosis subjects: pharmacokinetics and safety Pediatr. Pulm. 42 2007 307 313
-
(2007)
Pediatr. Pulm.
, vol.42
, pp. 307-313
-
-
Geller, D.E.1
-
90
-
-
0038826781
-
Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers
-
M.T. Newhouse et al. Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers Chest 124 2003 360 366
-
(2003)
Chest
, vol.124
, pp. 360-366
-
-
Newhouse, M.T.1
-
91
-
-
79951840468
-
Tobramycin inhalation powder for P. Aeruginosa infection in cystic fibrosis: The EVOLVE trial
-
M.W. Konstan et al. Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: the EVOLVE trial Pediatr. Pulmonol. 46 2011 230 238
-
(2011)
Pediatr. Pulmonol.
, vol.46
, pp. 230-238
-
-
Konstan, M.W.1
-
92
-
-
78651412529
-
Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial
-
M.W. Konstan et al. Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: the EAGER trial J. Cyst. Fibros. 10 2011 54 61
-
(2011)
J. Cyst. Fibros.
, vol.10
, pp. 54-61
-
-
Konstan, M.W.1
-
93
-
-
1542404791
-
Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics
-
L. Dellamary et al. Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics J. Control. Release 95 2004 489 500
-
(2004)
J. Control. Release
, vol.95
, pp. 489-500
-
-
Dellamary, L.1
-
94
-
-
84885841052
-
Tolerability and pharmacokinetic properties of ciprofloxacin dry powder for inhalation in patients with cystic fibrosis: A phase I, randomized, dose-escalation study
-
H. Stass et al. Tolerability and pharmacokinetic properties of ciprofloxacin dry powder for inhalation in patients with cystic fibrosis: a phase I, randomized, dose-escalation study Clin. Ther. 35 2013 1571 1581
-
(2013)
Clin. Ther.
, vol.35
, pp. 1571-1581
-
-
Stass, H.1
-
95
-
-
0034001190
-
Novel lipid-based hollow-porous microparticles as a platform for immunoglobulin delivery to the respiratory tract
-
A.I. Bot et al. Novel lipid-based hollow-porous microparticles as a platform for immunoglobulin delivery to the respiratory tract Pharm. Res. 17 2000 275 283
-
(2000)
Pharm. Res.
, vol.17
, pp. 275-283
-
-
Bot, A.I.1
-
96
-
-
79961039597
-
Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere™ technology
-
D.E. Geller et al. Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere™ technology J. Aerosol. Med. Pulm. Drug Deliv. 24 2011 175 182
-
(2011)
J. Aerosol. Med. Pulm. Drug Deliv.
, vol.24
, pp. 175-182
-
-
Geller, D.E.1
-
97
-
-
77954759958
-
Engineering gas-foamed large porous particles for efcient local delivery of macromolecules to the lung
-
F. Ungaro et al. Engineering gas-foamed large porous particles for efcient local delivery of macromolecules to the lung Eur. J. Pharm. Sci. 41 2010 60 70
-
(2010)
Eur. J. Pharm. Sci.
, vol.41
, pp. 60-70
-
-
Ungaro, F.1
-
98
-
-
34547666985
-
Inhaled dry powder insulin for the treatment of diabetes mellitus
-
S.M. Setter et al. Inhaled dry powder insulin for the treatment of diabetes mellitus Clin. Ther. 29 2007 795 813
-
(2007)
Clin. Ther.
, vol.29
, pp. 795-813
-
-
Setter, S.M.1
-
99
-
-
0033814073
-
A self-complementary, self-assembling microsphere system: Application for intravenous delivery of the antiepileptic and neuroprotectant compound felbamate
-
H. Lian et al. A self-complementary, self-assembling microsphere system: application for intravenous delivery of the antiepileptic and neuroprotectant compound felbamate J. Pharm. Sci. 89 2000 867 875
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 867-875
-
-
Lian, H.1
-
100
-
-
0011254169
-
Continuous sc infusion with glucagon and intermittent sc treatment with octreotide in persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI)
-
K. Mohnike et al. Continuous sc infusion with glucagon and intermittent sc treatment with octreotide in persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI) Exp. Clin. Endocrinol. Diabetes 108 2000 S127
-
(2000)
Exp. Clin. Endocrinol. Diabetes
, vol.108
, pp. 127
-
-
Mohnike, K.1
-
101
-
-
0036025088
-
Technosphere™/Insulin-a new approach for effective delivery of human insulin via the pulmonary route
-
A. Pfützner et al. Technosphere™/Insulin-a new approach for effective delivery of human insulin via the pulmonary route Diabetes Technol. Ther. 4 2002 589 594
-
(2002)
Diabetes Technol. Ther.
, vol.4
, pp. 589-594
-
-
Pfützner, A.1
-
102
-
-
78650109475
-
Technosphere® technology: A platform for inhaled protein therapeutics
-
A. Leone-Bay, and M. Grant Technosphere® technology: a platform for inhaled protein therapeutics ONDrugDelivery 2006 8 11
-
(2006)
ONDrugDelivery
, pp. 8-11
-
-
Leone-Bay, A.1
Grant, M.2
-
103
-
-
79952390914
-
Technosphere insulin: An inhaled mealtime insulin for the treatment of type 1 and type 2 diabetes mellitus
-
O.J. Phung Technosphere insulin: an inhaled mealtime insulin for the treatment of type 1 and type 2 diabetes mellitus Formulary 46 2011 14 17
-
(2011)
Formulary
, vol.46
, pp. 14-17
-
-
Phung, O.J.1
-
105
-
-
0033732478
-
Pharmaceutical excipient development: The need for preclinical guidance
-
P. Baldrick Pharmaceutical excipient development: the need for preclinical guidance Regul. Toxicol. Pharm. 32 2000 210 218
-
(2000)
Regul. Toxicol. Pharm.
, vol.32
, pp. 210-218
-
-
Baldrick, P.1
-
106
-
-
1842429885
-
Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures
-
N. Islam et al. Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures J. Pharm. Sci. 93 2004 1030 1038
-
(2004)
J. Pharm. Sci.
, vol.93
, pp. 1030-1038
-
-
Islam, N.1
-
107
-
-
23144445286
-
Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug
-
V.V. Sethuraman, and A.J. Hickey Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug AAPS PharmSciTech 3 2002 7 16
-
(2002)
AAPS PharmSciTech
, vol.3
, pp. 7-16
-
-
Sethuraman, V.V.1
Hickey, A.J.2
-
108
-
-
84858623292
-
Physico-chemical aspects of lactose for inhalation
-
X. Kou et al. Physico-chemical aspects of lactose for inhalation Am. J. Drug Deliv. 64 2012 220 232
-
(2012)
Am. J. Drug Deliv.
, vol.64
, pp. 220-232
-
-
Kou, X.1
-
109
-
-
22544457534
-
Carriers in drug powder delivery: Implications for inhalation system design
-
H.D. Smyth, and A.J. Hickey Carriers in drug powder delivery: implications for inhalation system design Am. J. Drug Deliv. 3 2005 117 132
-
(2005)
Am. J. Drug Deliv.
, vol.3
, pp. 117-132
-
-
Smyth, H.D.1
Hickey, A.J.2
-
110
-
-
2442459796
-
® and its absorption in healthy volunteers
-
® and its absorption in healthy volunteers J. Control. Release 97 2004 19 29
-
(2004)
J. Control. Release
, vol.97
, pp. 19-29
-
-
Nakate, T.1
-
112
-
-
0028814516
-
Dose emissions from marketed dry powder inhalers
-
M. Hindle, and P.R. Byron Dose emissions from marketed dry powder inhalers Int. J. Pharm. 116 1995 169 177
-
(1995)
Int. J. Pharm.
, vol.116
, pp. 169-177
-
-
Hindle, M.1
Byron, P.R.2
-
113
-
-
0030581128
-
Inhalation characteristics and their effects on in vitro drug delivery from dry powder inhalers. Part 2: Effect of peak flow rate (PIFR) and inspiration time on the in vitro drug release from three different types of commercial dry powder inhalers
-
A. De Boer et al. Inhalation characteristics and their effects on in vitro drug delivery from dry powder inhalers. Part 2: effect of peak flow rate (PIFR) and inspiration time on the in vitro drug release from three different types of commercial dry powder inhalers Int. J. Pharm. 138 1996 45 56
-
(1996)
Int. J. Pharm.
, vol.138
, pp. 45-56
-
-
De Boer, A.1
|