Anti-inflammatory effects of high-density lipoprotein through activating transcription factor 3: Benefit beyond cholesterol transport-dependent processes

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 6, 2014, Pages

  Zhang, Hanrui ^a   Reilly, Muredach P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

commentary; HDL cholesterol; inflammation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; HIGH DENSITY LIPOPROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

ANTIINFLAMMATORY ACTIVITY; BINDING SITE; BLOOD; BREAST IMPLANT; CHOLESTEROL TRANSPORT; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CYTOKINE PRODUCTION; HISTONE ACETYLATION; HUMAN; INNATE IMMUNITY; MACROPHAGE; MONONUCLEAR CELL; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

COMMENTARY; HDL CHOLESTEROL; INFLAMMATION;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ATHEROSCLEROSIS; CHOLESTEROL; FEMALE; HUMANS; INFLAMMATION; LIPOPROTEINS, HDL; MACROPHAGES;

EID: 84901491482     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303553     Document Type: Note

References (7)

1. Sorci-Thomas MG, Thomas MJ. High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. Arterioscler Thromb Vasc Biol. 2012;32:2561-2565.
2. De Nardo D, Labzin LI, Kono H, et al. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. 2014;15:152-160.
3. Gold ES, Ramsey SA, Sartain MJ, Selinummi J, Podolsky I, Rodriguez DJ, Moritz RL, Aderem A. ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation. J Exp Med. 2012;209:807-817.
4. Xia P, Vadas MA, Rye KA, Barter PJ, Gamble JR. High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL. J Biol Chem. 1999;274:33143- 33147. (Pubitemid 129535357)
5. Murphy AJ, Woollard KJ, Hoang A, Mukhamedova N, Stirzaker RA, McCormick SP, Remaley AT, Sviridov D, Chin-Dusting J. High-density lipoprotein reduces the human monocyte inflammatory response. Arterioscler Thromb Vasc Biol. 2008;28:2071-2077.
6. Tölle M, Pawlak A, Schuchardt M, Kawamura A, Tietge UJ, Lorkowski S, Keul P, Assmann G, Chun J, Levkau B, van der Giet M, Nofer JR. HDL associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production. Arterioscler Thromb Vasc Biol. 2008;28:1542-1548.
7. Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science. 2010;328:1689-1693.