Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in Albanian overweight children

Minerva Pediatrica

Volumn 66, Issue 1, 2014, Pages 23-30

  Kodhelaj, K ^a   Resuli, B ^b   Petrela, E ^c   Malaj, V ^a   Jaze, H ^d  

^a Speciality Polyclinic Nr 2 of Tirana ^*  (Albania)

^b UNIVERSITY HOSPITAL CENTER MOTHER TERESA   (Albania)

^c UNIVERSITY OF TIRANA   (Albania)

^d Service of Pediatrics Hospital of Vlore   (Albania)

Author keywords

Child; Nonalcoholic fatty liver disease; Overweight; Ultrasonography

Indexed keywords

ALANINE AMINOTRANSFERASE; CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ADOLESCENT; ALBANIAN (PEOPLE); ARTICLE; BIOCHEMISTRY; BODY MASS; BODY WEIGHT; CHILD; CHILDHOOD OBESITY; CHOLESTEROL BLOOD LEVEL; DEMOGRAPHY; DIET RESTRICTION; DISEASE SEVERITY; ECHOGRAPHY; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; INSULINEMIA; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; PREDICTOR VARIABLE; RISK FACTOR; SCORING SYSTEM; WAIST CIRCUMFERENCE;

ADOLESCENT; ALBANIA; CHILD; FATTY LIVER; FEMALE; HUMANS; MALE; OVERWEIGHT; PREVALENCE; SEVERITY OF ILLNESS INDEX;

EID: 84901489442     PISSN: 00264946     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Hedley AA, Ogden CL, Johnson CL, Carrol MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among VS children, adolescents and adults, 1999-2002. JAMA 2004;291:2877-50.
2. Saraf JM, Lai D, Turner J, Poffenbarger T, Portman RJ. Overweight, ethnicity and the prevalence of hypertension in school aged children. Pediatrics 2004;113:475-82. (Pubitemid 38280786)
3. Ford ES, Mokdad AH., Ajani UA. Trends INS risk factors for cardiovascular disease among children and adolescents in the United States. Pediatrics 2004;114:1534-44. (Pubitemid 41754915)
4. Cook S, Wetzman M, Aringer P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents: finding from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pedriatic Adolescents Medicine 2003;157:821-7. (Pubitemid 36988016)
5. Franzese A, Vajro P, Argenziano A, Puzziello A, Iannucci MP, Saviano MC et al. Liver involvement in obese children. Ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population. Dig Dis Sci 1997;42:1428-32. (Pubitemid 27339358)
6. Tazawa Y, Noguchi H, Nishignomiya F, Takada G. Serum alanine aminotransferase activity in obese children. Acta Pediatric 1997;86:238-41. (Pubitemid 27135267)
7. Strauss RS, Barlow SE, Dietz WH. Prevalence of abnormal serum aminotransferase values in overweight and obese adolescents. J Pediatric 2000;136:727-33. (Pubitemid 30415644)
8. Chan DF, Li AM, Chu WC, Chan MH, Wong EM, Liu EK et al. Hepatic steatosis in Chinese obese children. Int J Obese Relate Metab Disorders 2004;28:1257-63 (Pubitemid 39389582)
9. Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C. Prevalence of fatty liver in children and adolescents. Pediatric 2006;118:1388-93. (Pubitemid 46393782)
10. Schwimmer JB, McGreal N, Deutsch R, Finegold MJ, Lavine JE. Influence of gender, race and ethnicity on suspected fatty liver in obese adolescents. Pediatric 2005;115:e561-e5.
11. Feldstein AE, Papouchado BG, Angulo P, Sanderson S, Adams L, Gores GJ. Hepatic stelate cells and fibrosis progression in patients with fatty liver disease. Clin Gastroenterology Hepatology 2005;3:284-9.
12. Molleston JP, White F, Teckman J, Fitzgerald JF. Obese children with steatohepatitis can develop cirrhosis in childhood, AM J. Gastroenterology 2002;97:2460-2.
13. Bugianesi E, Leone N, Vanni E, Marchesini G, Brunello F, Carucci P et al. Expanding the natural history on nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002;123:134-40. (Pubitemid 34747534)
14. Feldstein AE, Charatcharoenwithaya P, Treeprasert Suk S, Benson JE, Angulo P. The natural history of nonalcoholic fatty liver disease: a follow-up study for up to 20 years. Gut 2009;58:15-38.
15. Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, Natale S et al. Nonalcoholic fatty liver steatohepatitis and the metabolic syndrome. Hepatology 2003;37:917-23. (Pubitemid 36397405)
16. De Bruyne RML, Fitzpatrick E, Dhawan A. Fatty liver disease in children: eat now pay latter. Hepatology In 2010;4:375-85.
17. WHO Expert Committee on Diabetes Mellitus. Second Report. Technical Report Series No 626, Geneva: WHO; 1980.
18. Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ et al. Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology 2005;42:641-9. (Pubitemid 41233657)
19. Tominga K, Kurata JH, Chen YK, Fujimoto E, Miyagawa S, Abe I et al. Prevalence of fatty liver in Japanese children and relationship with obesity. An epidemiological ultrasonography survey. Dig Dis Sci 1995;40:2002-9.
20. Wilfred De Alvis NM, Day CHP. Nonalcoholic fatty liver disease: The whist gradually clears. J Hepatology 2008;48:S104-S12.
21. Less SS, Park SH, Kim HJ. Noninvasive assessment of hepatic steatosis: Prospective comparison of the occurrence of imaging examinations. J Hepatology 200;52:579-82.
22. Saadeh S, Younossi ZM, Renter EM, Gramlich T, Ong JP, Hurley M et al. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology 2002;123:745-50. (Pubitemid 34977081)
23. Sagi R, Reif S, Neuman G, Webb M, Phillip M, Shalitin S. Nonalcoholic fatty liver disease in overweight children and adolescents. Acta Pediatric 2007;96:1289-13.
24. Kojima S, Watanabe N, Numata M, Ogawa T, Matsuzaki S. Increase of prevalence of fatty liver in Japan over the first 12 years: analysis of clinical background. J Gastroenterology 2003;38:954-61. (Pubitemid 37455782)
25. th percentile. J Pediatr Gastroenterol Nutr 2007;44:229-36.
26. Kawasaki T, Hashimoto N, Kikuchi T, Takahashi H, Uchiyama M. The relationship between fatty liver and hyperinsulinemia in obese Japanese children. J Pediatr Gastroenterol Nutr 1997;24:317-21. (Pubitemid 27199621)
27. Manton ND, Lipsett J, Moore DJ, Davidson GP, Bourne AJ. Nonalcoholic steatohepatitis in children and adolescents. Med J Aust 2000;173:476-9.
28. Schwimmer JB, Deutsch R, Rauch JB, Behling C, Newbury R, Lavine JL. Obesity, insulin resistance and other clinical-pathological correlates of pediatric nonalcoholic fatty liver disease. J Pediatric 2003;143:500-5. (Pubitemid 37352510)
29. Lavine JE, Schwimmer JB. NAFLD/NASH in children. In: Farrell G, George J, Hall P, McCullough A, editors. Fatty liver disease: NASH and related disorders. Oxford, England: Blackwell Publishing; 2004. p. 229-40.
30. Arun J, Clements RH, Lazenby AJ, Leeth RR, Abrams GA. The prevalence of nonalcoholic steatohepatitis is greater in morbidity obese man compared to women. Obst Surg 2006;16:1351-8. (Pubitemid 44671809)
31. Galloway PJ, Donaldson MDC, Wallance AM. Sex hormone binding globulin concentration as a pubertal marker for Hyperinsulinemia in obesity. Arch Dis Child 2001;85:489-91. (Pubitemid 33116482)
32. Adams LA, Lymp JF, St Sauver J, Sanderson SO, Lindor KD, Feldstein A, Angulo P. The natural history of nonalcoholic fatty liver disease: a population based cohort study. Gastroenterology 2005;129:115-20.
33. Ekstedt M, Franzén LE, Mathiesen UL, Thorelius L, Holmqvist M, Bodemar G, Kechagias S. Long-term follow-up of patients with NAFLD and elevated liver enzyme. Hepatology 2006;44:865-73. (Pubitemid 46489550)
34. Wieckowska A, McCullough AJ, Feldstein AL. Noninvasive and monitoring of nonalcoholic steatohepatitis: Present and future. Hepatology 2007;46:582-9. (Pubitemid 47344794)
35. Yano E, Tagawa K, Yamaoka K, Mori M. Test validity of periodic liver function tests in a population of Japanese male bank employees. J Clinic Epidemiology 2001;54:945-51. (Pubitemid 32755785)
36. Nomura K, Yano E, Shinozaki T, Tagawa K., Efficacy and effectiveness of liver screening to detect fatty liver in the periodic health check-ups. J Occup Health 2004;46:423-8. (Pubitemid 40007568)
37. Marchesini G, Marzocchi R, Natale S. NAFLD-Why not to treat the insulin resistance? BASL monothematic conference: nonalcoholic steatohepatitis: from cell biology to clinical practice. Estoril, Portugal, 2004. p. 64-70.
38. Bugianesi E, McCullough AJ, Merchesini G. Insulin resistance: a metabolic pathway to chronic liver diseases, Hepatology 2005;42:987-1000. (Pubitemid 43112663)
39. Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, Karim R et al. NASH and insulin resistance: insulin hyper secretion and specific association with the insulin resistance syndrome. Hepatology 2002;35:373-9. (Pubitemid 34106377)
40. McCullough AJ. Path physiology of nonalcoholic steatohepatitis. J Gastrointestinal 2006;40(Suppl. 1):S17-S29.
41. Larter C, Farrell GC. Insulin resistance, adiponectina, and cytokines in NASH: which the best target to treat? J Hepatology 2006;44:253-61. (Pubitemid 43071224)