Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity

Journal of Neuroscience

Volumn 34, Issue 22, 2014, Pages 7663-7676

  Clarke, Hannah F ^a,b   Cardinal, R N ^b,c,d   Rygula, R ^a,b   Hong, Y T ^c   Fryer, T D ^c   Sawiak, S J ^b,c   Ferrari, V ^c   Cockcroft, G ^a,b   Aigbirhio, F I ^b,c   Robbins, T W ^a,b   Roberts, A C ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

^d CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Behavior; Caudate nucleus; Dopamine; Orbitofrontal cortex; PET; Schizophrenia

Indexed keywords

BRAIN MONOAMINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; FALLYPRIDE F 18; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BAYES THEOREM; BEHAVIOR CHANGE; CALLITHRIX; CATECHOLAMINE DEPLETION; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DOPAMINE DEPLETION; FEMALE; HISTOCHEMISTRY; MALE; MICRODIALYSIS; NEUROTRANSMISSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ORBITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING; REINFORCEMENT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCHIZOPHRENIA; UPREGULATION;

BEHAVIOR; CAUDATE NUCLEUS; DOPAMINE; ORBITOFRONTAL CORTEX; PET; SCHIZOPHRENIA;

ANIMALS; CALLITHRIX; CAUDATE NUCLEUS; DOPAMINE; FEMALE; FRONTAL LOBE; LEARNING; MALE; REINFORCEMENT (PSYCHOLOGY); UP-REGULATION;

EID: 84901452662     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0718-14.2014     Document Type: Article

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