UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome

Biomedical Chromatography

Volumn 28, Issue 6, 2014, Pages 831-838

  Takayama, Takahiro ^a   Suzuki, Mayu ^a   Todoroki, Kenichiro ^a   Inoue, Koichi ^a   Min, Jun Zhe ^a   Kikura Hanajiri, Ruri ^b   Goda, Yukihiro ^b   Toyo'oka, Toshimasa ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Human liver microsome; Illicit drugs; LC ESI MS MS; Metabolism

Indexed keywords

CARBOXYLATION; CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; ENZYMES; ESTERS; MASS SPECTROMETRY; METABOLISM; OXIDATION; PHYSIOLOGY; POLYCYCLIC AROMATIC HYDROCARBONS;

CARBOXAMIDES; ESI-MS-MS; HUMAN LIVER MICROSOMES; ILLICIT DRUG; INDAZOLE; LC MS/MS(ESI); LC-ESI-MS/MS; LC/ESI-MS/MS; QUINOLINOL; REVERSED PHASE CHROMATOGRAPHY;

METABOLITES;

CYTOCHROME P450; ESTER; ILLICIT DRUG; INDAZOLE DERIVATIVE; INDOLE; INDOLEACETIC ACID; QUINOLINOL DERIVATIVE; THIOPHENE; STREET DRUG;

ARTICLE; DRUG METABOLISM; DRUG STRUCTURE; LIVER MICROSOME; MASS SPECTROMETRY; OXIDATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EVALUATION STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; PROCEDURES; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MICROSOMES, LIVER; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREET DRUGS; TANDEM MASS SPECTROMETRY;

EID: 84901441981     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3155     Document Type: Article

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