메뉴 건너뛰기




Volumn 102, Issue 3, 2014, Pages 429-435

Vessel wall, not platelet, P2Y12 potentiates early atherogenesis

Author keywords

Atherogenesis; Clopidogrel; P2Y12; Platelet; Ticagrelor

Indexed keywords

APOLIPOPROTEIN E; CLOPIDOGREL; PADGEM PROTEIN; PURINERGIC P2Y12 RECEPTOR; TICAGRELOR; ADENOSINE; P2RY12 PROTEIN, MOUSE; TICLOPIDINE;

EID: 84901432081     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvu028     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002;420: 868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 2
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999;340: 115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 3
    • 0029151086 scopus 로고
    • A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
    • Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, Insull W Jr., et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb Vasc Biol 1995;15: 1512-1531.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1512-1531
    • Stary, H.C.1    Chandler, A.B.2    Dinsmore, R.E.3    Fuster, V.4    Glagov, S.5    Insull Jr., W.6
  • 4
    • 0028208606 scopus 로고
    • Adefinition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
    • Stary HC, Chandler AB, Glagov S, Guyton JR, Insull W Jr, Rosenfeld ME et al. Adefinition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb Vasc Biol 1994;14: 840-856.
    • (1994) Arterioscler Thromb Vasc Biol , vol.14 , pp. 840-856
    • Stary, H.C.1    Chandler, A.B.2    Glagov, S.3    Guyton, J.R.4    Insull Jr. W5    Rosenfeld, M.E.6
  • 5
  • 6
    • 0035799376 scopus 로고    scopus 로고
    • RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium
    • von Hundelshausen P, Weber KS, Huo Y, Proudfoot AE, Nelson PJ, Ley K et al. RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation 2001;103: 1772-1777.
    • (2001) Circulation , vol.103 , pp. 1772-1777
    • Von Hundelshausen, P.1    Weber, K.S.2    Huo, Y.3    Proudfoot, A.E.4    Nelson, P.J.5    Ley, K.6
  • 7
    • 0033990516 scopus 로고    scopus 로고
    • Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis
    • Gawaz M, Brand K, Dickfeld T, Pogatsa-MurrayG, Page S, BognerCet al. Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis. Atherosclerosis 2000;148: 75-85.
    • (2000) Atherosclerosis , vol.148 , pp. 75-85
    • Gawaz, M.1    Brand, K.2    Dickfeld, T.3    Pogatsa-Murray, G.4    Page, S.5    Bogner, C.6
  • 8
    • 0242317417 scopus 로고    scopus 로고
    • Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells
    • Massberg S, Vogt F, Dickfeld T, Brand K, Page S, Gawaz M. Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells. Thromb Res 2003;110: 187-194.
    • (2003) Thromb Res , vol.110 , pp. 187-194
    • Massberg, S.1    Vogt, F.2    Dickfeld, T.3    Brand, K.4    Page, S.5    Gawaz, M.6
  • 9
    • 0030657667 scopus 로고    scopus 로고
    • Aggregating human platelets stimulate the expression of thrombin receptors in cultured vascular smooth muscle cells via the release of transforming growth factor-beta1 and platelet-derived growth factorAB
    • Schini-Kerth VB, Bassus S, Fisslthaler B, Kirchmaier CM, Busse R. Aggregating human platelets stimulate the expression of thrombin receptors in cultured vascular smooth muscle cells via the release of transforming growth factor-beta1 and platelet-derived growth factorAB. Circulation 1997;96: 3888-3896.
    • (1997) Circulation , vol.96 , pp. 3888-3896
    • Schini-Kerth, V.B.1    Bassus, S.2    Fisslthaler, B.3    Kirchmaier, C.M.4    Busse, R.5
  • 10
    • 77955276576 scopus 로고    scopus 로고
    • Impact of glycoprotein VI and platelet adhesion on atherosclerosis-a possible role of fibronectin
    • Bultmann A, Li Z, Wagner S, Peluso M, Schonberger T, Weis Cet al. Impact of glycoprotein VI and platelet adhesion on atherosclerosis-a possible role of fibronectin. J Mol Cell Cardiol 2010;49: 532-542.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 532-542
    • Bultmann, A.1    Li, Z.2    Wagner, S.3    Peluso, M.4    Schonberger, T.5    Weis, C.6
  • 11
    • 0037769793 scopus 로고    scopus 로고
    • Platelet P-selectin facilitates atherosclerotic lesion development
    • Burger PC, Wagner DD. Platelet P-selectin facilitates atherosclerotic lesion development. Blood 2003;101: 2661-2666.
    • (2003) Blood , vol.101 , pp. 2661-2666
    • Burger, P.C.1    Wagner, D.D.2
  • 12
    • 0037037566 scopus 로고    scopus 로고
    • A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation
    • Massberg S, Brand K, Gruner S, Page S, Muller E, Muller I et al. A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation. J Exp Med 2002;196: 887-896.
    • (2002) J Exp Med , vol.196 , pp. 887-896
    • Massberg, S.1    Brand, K.2    Gruner, S.3    Page, S.4    Muller, E.5    Muller, I.6
  • 13
    • 0037231665 scopus 로고    scopus 로고
    • Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein e
    • Huo Y, Schober A, Forlow SB, Smith DF, Hyman MC, Jung S et al. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat Med 2003;9: 61-67.
    • (2003) Nat Med , vol.9 , pp. 61-67
    • Huo, Y.1    Schober, A.2    Forlow, S.B.3    Smith, D.F.4    Hyman, M.C.5    Jung, S.6
  • 14
    • 0033760391 scopus 로고    scopus 로고
    • The central role of the P2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity
    • Storey RF, Sanderson HM, White AE, May JA, Cameron KE, Heptinstall S. The central role of the P2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity. Br J Haematol 2000;110: 925-934.
    • (2000) Br J Haematol , vol.110 , pp. 925-934
    • Storey, R.F.1    Sanderson, H.M.2    White, A.E.3    May, J.A.4    Cameron, K.E.5    Heptinstall, S.6
  • 15
    • 84856158305 scopus 로고    scopus 로고
    • ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)
    • Guidelines ESCCfP
    • HammCW, Bassand JP, Agewall S, Bax J, Boersma E, Bueno H et al. Guidelines ESCCfP. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2011;32: 2999-3054.
    • (2011) Eur Heart J , vol.32 , pp. 2999-3054
    • Hamm, C.W.1    Bassand, J.P.2    Agewall, S.3    Bax, J.4    Boersma, E.5    Bueno, H.6
  • 16
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345: 494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 18
    • 77958003916 scopus 로고    scopus 로고
    • Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: The PLATO (PLATelet inhibition and patient Outcomes) PLATELET substudy
    • Storey RF, Angiolillo DJ, Patil SB, Desai B, Ecob R, Husted S et al. Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: The PLATO (PLATelet inhibition and patient Outcomes) PLATELET substudy. J Am Coll Cardiol 2010;56: 1456-1462.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 1456-1462
    • Storey, R.F.1    Angiolillo, D.J.2    Patil, S.B.3    Desai, B.4    Ecob, R.5    Husted, S.6
  • 19
    • 59049098880 scopus 로고    scopus 로고
    • Platelet P2Y( 12) receptor influences the vessel wall response to arterial injury and thrombosis
    • Evans DJ, Jackman LE, Chamberlain J, Crosdale DJ, Judge HM, Jetha K et al. Platelet P2Y(12) receptor influences the vessel wall response to arterial injury and thrombosis. Circulation 2009;119: 116-122.
    • (2009) Circulation , vol.119 , pp. 116-122
    • Evans, D.J.1    Jackman, L.E.2    Chamberlain, J.3    Crosdale, D.J.4    Judge, H.M.5    Jetha, K.6
  • 20
    • 78650419541 scopus 로고    scopus 로고
    • Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima
    • Patil SB, Jackman LE, Francis SE, Judge HM, Nylander S, Storey RF. Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima. Arterioscler Thromb Vasc Biol 2010;30: 2385-2391.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2385-2391
    • Patil, S.B.1    Jackman, L.E.2    Francis, S.E.3    Judge, H.M.4    Nylander, S.5    Storey, R.F.6
  • 22
    • 78650420253 scopus 로고    scopus 로고
    • Regulation of functionally active P2Y12ADPreceptors by thrombin in human smoothmuscle cells and the presence of P2Y12 in carotid artery lesions
    • Rauch BH, Rosenkranz AC, Ermler S, Bohm A, Driessen J, Fischer JW et al. Regulation of functionally active P2Y12ADPreceptors by thrombin in human smoothmuscle cells and the presence of P2Y12 in carotid artery lesions. Arterioscler Thromb Vasc Biol 2010;30: 2434-2442.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2434-2442
    • Rauch, B.H.1    Rosenkranz, A.C.2    Ermler, S.3    Bohm, A.4    Driessen, J.5    Fischer, J.W.6
  • 23
    • 84864284484 scopus 로고    scopus 로고
    • Roles of purinergic receptor P2Y, G protein-coupled 12 in the development of atherosclerosis in apolipoprotein E-deficient mice
    • Li D, Wang Y, Zhang L, Luo X, Li J, Chen X et al. Roles of purinergic receptor P2Y, G protein-coupled 12 in the development of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2012;32: E81-e89.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32
    • Li, D.1    Wang, Y.2    Zhang, L.3    Luo, X.4    Li, J.5    Chen, X.6
  • 24
    • 84866479608 scopus 로고    scopus 로고
    • Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model
    • van Giezen JJ, Sidaway J, Glaves P, Kirk I, Bjorkman JA. Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model. J Cardiovasc Pharmacol Therapeut 2012;17: 164-172.
    • (2012) J Cardiovasc Pharmacol Therapeut , vol.17 , pp. 164-172
    • Van Giezen, J.J.1    Sidaway, J.2    Glaves, P.3    Kirk, I.4    Bjorkman, J.A.5
  • 25
    • 77953293012 scopus 로고    scopus 로고
    • The reversible oralP2Y12 antagonist AZD6140 inhibits ADP-induced contractions in murine and human vasculature
    • Hogberg C, Svensson H, Gustafsson R, Eyjolfsson A, Erlinge D. The reversible oralP2Y12 antagonist AZD6140 inhibits ADP-induced contractions in murine and human vasculature. Int J Cardiol 2010;142: 187-192.
    • (2010) Int J Cardiol , vol.142 , pp. 187-192
    • Hogberg, C.1    Svensson, H.2    Gustafsson, R.3    Eyjolfsson, A.4    Erlinge, D.5
  • 26
    • 0034978187 scopus 로고    scopus 로고
    • Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs
    • Foster CJ, Prosser DM, Agans JM, Zhai Y, Smith MD, Lachowicz JE et al. Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. J Clin Invest 2001;107: 1591-1598.
    • (2001) J Clin Invest , vol.107 , pp. 1591-1598
    • Foster, C.J.1    Prosser, D.M.2    Agans, J.M.3    Zhai, Y.4    Smith, M.D.5    Lachowicz, J.E.6
  • 27
    • 0026536066 scopus 로고
    • Generation of mice carrying a mutant apolipoprotein e gene inactivated by gene targeting in embryonic stem cells
    • Piedrahita JA, Zhang SH, Hagaman JR, Oliver PM, Maeda N. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci USA 1992;89: 4471-4475.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4471-4475
    • Piedrahita, J.A.1    Zhang, S.H.2    Hagaman, J.R.3    Oliver, P.M.4    Maeda, N.5
  • 28
    • 33645454887 scopus 로고    scopus 로고
    • Interleukin-1 beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice
    • Chamberlain J, Evans D, King A, Dewberry R, Dower S, Crossman D et al. Interleukin-1 beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice. Am J Pathol 2006;168: 1396-1403.
    • (2006) Am J Pathol , vol.168 , pp. 1396-1403
    • Chamberlain, J.1    Evans, D.2    King, A.3    Dewberry, R.4    Dower, S.5    Crossman, D.6
  • 30
    • 77953158260 scopus 로고    scopus 로고
    • Heterozygous antithrombin deficiency improves in vivo haemostasis in factor VIII-deficient mice
    • Bolliger D, Szlam F, Suzuki N, Matsushita T, Tanaka KA. Heterozygous antithrombin deficiency improves in vivo haemostasis in factor VIII-deficient mice. Thromb Haemost 2010; 103: 1233-1238.
    • (2010) Thromb Haemost , vol.103 , pp. 1233-1238
    • Bolliger, D.1    Szlam, F.2    Suzuki, N.3    Matsushita, T.4    Tanaka, K.A.5
  • 31
    • 0037126048 scopus 로고    scopus 로고
    • Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury
    • Schober A, Manka D, von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ et al. Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury. Circulation 2002;106: 1523-1529.
    • (2002) Circulation , vol.106 , pp. 1523-1529
    • Schober, A.1    Manka, D.2    Von Hundelshausen, P.3    Huo, Y.4    Hanrath, P.5    Sarembock, I.J.6
  • 32
    • 50349083450 scopus 로고    scopus 로고
    • Reduced atherosclerotic lesions in P2Y1/apolipoprotein e double-knockout mice: The contribution of non-hematopoietic-derived P2Y1 receptors
    • Hechler B, Freund M, Ravanat C, Magnenat S, Cazenave JP, Gachet C. Reduced atherosclerotic lesions in P2Y1/apolipoprotein E double-knockout mice: The contribution of non-hematopoietic-derived P2Y1 receptors. Circulation 2008;118: 754-763.
    • (2008) Circulation , vol.118 , pp. 754-763
    • Hechler, B.1    Freund, M.2    Ravanat, C.3    Magnenat, S.4    Cazenave, J.P.5    Gachet, C.6
  • 33
    • 64049094289 scopus 로고    scopus 로고
    • Clopidogrel attenuates atheroma formation and induces a stable plaque phenotype in apolipoprotein e knockout mice
    • Afek A, Kogan E, Maysel-Auslender S, Mor A, Regev E, Rubinstein A et al. Clopidogrel attenuates atheroma formation and induces a stable plaque phenotype in apolipoprotein E knockout mice. Microvasc Res 2009;77: 364-369.
    • (2009) Microvasc Res , vol.77 , pp. 364-369
    • Afek, A.1    Kogan, E.2    Maysel-Auslender, S.3    Mor, A.4    Regev, E.5    Rubinstein, A.6
  • 34
    • 38349143321 scopus 로고    scopus 로고
    • Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo
    • Schulz C, Konrad I, Sauer S, Orschiedt L, Koellnberger M, LorenzRet al. Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo. Thromb Haemost 2008;99: 190-195.
    • (2008) Thromb Haemost , vol.99 , pp. 190-195
    • Schulz, C.1    Konrad, I.2    Sauer, S.3    Orschiedt, L.4    Koellnberger, M.5    Lorenz, R.6
  • 35
    • 84861830383 scopus 로고    scopus 로고
    • Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: A placebo-controlled study in rats
    • Grzesk G, Kozinski M, Navarese EP, Krzyzanowski M, Grzesk E, KubicaAet al. Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: A placebo-controlled study in rats. Thromb Res 2012;130: 65-69.
    • (2012) Thromb Res , vol.130 , pp. 65-69
    • Grzesk, G.1    Kozinski, M.2    Navarese, E.P.3    Krzyzanowski, M.4    Grzesk, E.5    Kubica, A.6
  • 36
    • 0031606913 scopus 로고    scopus 로고
    • Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells
    • Dubey RK, Gillespie DG, Jackson EK. Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells. Hypertension 1998;31: 296-302.
    • (1998) Hypertension , vol.31 , pp. 296-302
    • Dubey, R.K.1    Gillespie, D.G.2    Jackson, E.K.3
  • 37
    • 0028793485 scopus 로고
    • Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans
    • Smits P, Williams SB, Lipson DE, Banitt P, RongenGA, CreagerMA. Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans. Circulation 1995;92: 2135-2141.
    • (1995) Circulation , vol.92 , pp. 2135-2141
    • Smits, P.1    Williams, S.B.2    Lipson, D.E.3    Banitt, P.4    Rongen, G.A.5    Creager, M.A.6
  • 38
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr et al. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 1995;96: 60-68.
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone Jr., M.A.6
  • 39
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989;83: 1774-1777.
    • (1989) J Clin Invest , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.