Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 2597-2606

  Mas, Núria ^a,b   Galiana, Irene ^b   Hurtado, Silvia ^e   Mondragón, Laura ^a,b   Bernardos, Andrea ^a,b   Sancenón, Félix ^a,b   Marcos, María D ^a,b   Amorós, Pedro ^c   Abril Utrillas, Nuria ^d   Martínez Máñez, Ramón ^a,b   Murguía, José Ramón ^a,b  

^a UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

^d HOSPITAL DE LA PLANA   (Spain)

^e Servicio Ginecología y Obstetricia Hospital de la Plana ^*

Author keywords

Capped mesoporous nanoparticles; Intracellular release; pH responsive nanoparticles; Saccharomyces cerevisiae; Tebuconazole loading

Indexed keywords

MESOPOROUS NANOPARTICLE; NANOPARTICLE; TEBUCONAZOLE; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; DELAYED RELEASE FORMULATION; NANOCAPSULE; TRIAZOLE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CELL DEATH; COLONY FORMING UNIT; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; INTERNALIZATION; NANODEVICE; NONHUMAN; PH; TRANSMISSION ELECTRON MICROSCOPY; VAGINA MYCOSIS; X RAY POWDER DIFFRACTION; YEAST CELL; ADMINISTRATION AND DOSAGE; CELL SURVIVAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG EFFECTS; DRUG POTENTIATION; NANOPORE; PARTICLE SIZE; PHYSIOLOGY; POROSITY; SACCHAROMYCES CEREVISIAE; ULTRASTRUCTURE;

ANTIFUNGAL AGENTS; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG SYNERGISM; HYDROGEN-ION CONCENTRATION; NANOCAPSULES; NANOPORES; PARTICLE SIZE; POROSITY; SACCHAROMYCES CEREVISIAE; TRIAZOLES;

EID: 84901418187     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S59654     Document Type: Article

References (2)

1. Bernardos A, Aznar E, Coll C. Controlled release of vitamin B2 using mesoporous materials functionalized with amine-bearing gate-like scaffoldings. J Control Release. 2008;131(3):181-189.
2. Song SW, Hidajat K, Kawi S. pH-controllable drug release using hydrogel encapsulated mesoporous silica. Chem Comm. 2007;42:4396-4398.