CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

BMC Medicine

Volumn 12, Issue 1, 2014, Pages

  Edlund, Anna ^a   Esguerra, Jonathan L S ^a   Wendt, Anna ^a   Flodström Tullberg, Malin ^b   Eliasson, Lena ^a  

^a LUND UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Beta cell; CFTR; Cystic fibrosis; Diabetes; Exocytosis; Insulin secretion; Islet of langerhans

Indexed keywords

ANO1 PROTEIN, HUMAN; CALCIUM; CALCIUM CHANNEL; CHLORIDE CHANNEL; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FORSKOLIN; GLUCAGON LIKE PEPTIDE 1; GLYCINE; HYDRAZINE DERIVATIVE; INSULIN DERIVATIVE; ION CHANNEL; N-(2-NAPHTHALENYL)-((3,5-DIBROMO-2,4-DIHYDROXYPHENYL)METHYLENE)GLYCINE HYDRAZIDE; TUMOR PROTEIN;

ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CYSTIC FIBROSIS; EXOCYTOSIS; HUMAN; METABOLISM; MOUSE; PANCREAS ISLET BETA CELL; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; CALCIUM; CALCIUM CHANNELS; CHLORIDE CHANNELS; COLFORSIN; CYCLIC AMP; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EXOCYTOSIS; GLUCAGON-LIKE PEPTIDE 1; GLYCINE; HUMANS; HYDRAZINES; INSULIN-SECRETING CELLS; INSULINS; ION CHANNELS; MICE; NEOPLASM PROTEINS; PATCH-CLAMP TECHNIQUES;

EID: 84901399700     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-12-87     Document Type: Article

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