-
1
-
-
33746377894
-
Protein Misfolding, Functional Amyloid, and Human Disease
-
Chiti, F.; Dobson, C. M. Protein Misfolding, Functional Amyloid, and Human Disease Annu. Rev. Biochem. 2006, 75, 333-366
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
2
-
-
80052266213
-
The Amyloid Cascade Hypothesis for Alzheimer's Disease: An Appraisal for the Development of Therapeutics
-
Karran, E.; Mercken, M.; De Strooper, B. The Amyloid Cascade Hypothesis for Alzheimer's Disease: An Appraisal for the Development of Therapeutics Nat. Rev. Drug Discovery 2011, 10, 698-712
-
(2011)
Nat. Rev. Drug Discovery
, vol.10
, pp. 698-712
-
-
Karran, E.1
Mercken, M.2
De Strooper, B.3
-
3
-
-
12244285938
-
Molecular Basis for Amyloid Fibril Formation and Stability
-
Makin, O. S.; Atkins, E.; Sikorski, P.; Johansson, J.; Serpell, L. C. Molecular Basis for Amyloid Fibril Formation and Stability Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 315-320
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 315-320
-
-
Makin, O.S.1
Atkins, E.2
Sikorski, P.3
Johansson, J.4
Serpell, L.C.5
-
4
-
-
34249290108
-
Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers
-
Sawaya, M. R.; Sambashivan, S.; Nelson, R.; Ivanova, M. I.; Sievers, S. A.; Apostol, M. I.; Thompson, M. J.; Balbirnie, M.; Wiltzius, J. J. W.; McFarlane, H. T.; Madsen, A. O.; Riekel, C.; Eisenberg, D. Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers Nature 2007, 447, 453-457
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.I.4
Sievers, S.A.5
Apostol, M.I.6
Thompson, M.J.7
Balbirnie, M.8
Wiltzius, J.J.W.9
McFarlane, H.T.10
Madsen, A.O.11
Riekel, C.12
Eisenberg, D.13
-
5
-
-
33750017513
-
Molecular Structure of Amyloid Fibrils: Insights from Solid-State NMR
-
Tycko, R. Molecular Structure of Amyloid Fibrils: Insights from Solid-State NMR Q. Rev. Biophys. 2006, 39, 1-55
-
(2006)
Q. Rev. Biophys.
, vol.39
, pp. 1-55
-
-
Tycko, R.1
-
6
-
-
0033200063
-
Protein Misfolding, Evolution and Disease
-
Dobson, C. M. Protein Misfolding, Evolution and Disease Trends Biochem. Sci. 1999, 24, 329-332
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 329-332
-
-
Dobson, C.M.1
-
7
-
-
84876492200
-
The Supramolecular Chemistry of β-Sheets
-
Cheng, P. N.; Pham, J. D.; Nowick, J. S. The Supramolecular Chemistry of β-Sheets J. Am. Chem. Soc. 2013, 135, 5477-5492
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 5477-5492
-
-
Cheng, P.N.1
Pham, J.D.2
Nowick, J.S.3
-
10
-
-
84870548486
-
Breakdown of Nucleation Theory for Crystals with Strongly Anisotropic Interactions between Molecules
-
Cabriolu, R.; Kashchiev, D.; Auer, S. Breakdown of Nucleation Theory for Crystals with Strongly Anisotropic Interactions Between Molecules J. Chem. Phys. 2012, 137, 204903
-
(2012)
J. Chem. Phys.
, vol.137
, pp. 204903
-
-
Cabriolu, R.1
Kashchiev, D.2
Auer, S.3
-
11
-
-
77953556011
-
Nucleation of Amyloid Fibrils
-
Kashchiev, D.; Auer, S. Nucleation of Amyloid Fibrils J. Chem. Phys. 2010, 132, 215101
-
(2010)
J. Chem. Phys.
, vol.132
, pp. 215101
-
-
Kashchiev, D.1
Auer, S.2
-
12
-
-
78650335625
-
Atomistic Theory of Amyloid Fibril Nucleation
-
Cabriolu, R.; Kashchiev, D.; Auer, S. Atomistic Theory of Amyloid Fibril Nucleation J. Chem. Phys. 2010, 133, 225101
-
(2010)
J. Chem. Phys.
, vol.133
, pp. 225101
-
-
Cabriolu, R.1
Kashchiev, D.2
Auer, S.3
-
13
-
-
80455129087
-
Size Distribution of Amyloid Nanofibrils
-
Cabriolu, R.; Kashchiev, D.; Auer, S. Size Distribution of Amyloid Nanofibrils Biophys. J. 2011, 101, 2232-2241
-
(2011)
Biophys. J.
, vol.101
, pp. 2232-2241
-
-
Cabriolu, R.1
Kashchiev, D.2
Auer, S.3
-
14
-
-
84873867636
-
Confounding the Paradigm: Peculiarities of Amyloid Fibril Nucleation
-
Kashchiev, D.; Cabriolu, R.; Auer, S. Confounding the Paradigm: Peculiarities of Amyloid Fibril Nucleation J. Am. Chem. Soc. 2013, 135, 1531-1539
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 1531-1539
-
-
Kashchiev, D.1
Cabriolu, R.2
Auer, S.3
-
15
-
-
0042467550
-
Rationalization of the Effects of Mutations on Peptide and Protein Aggregation Rates
-
Chiti, F.; Stefani, M.; Taddei, N.; Ramponi, G.; Dobson, C. M. Rationalization of the Effects of Mutations on Peptide and Protein Aggregation Rates Nature 2003, 424, 805-808
-
(2003)
Nature
, vol.424
, pp. 805-808
-
-
Chiti, F.1
Stefani, M.2
Taddei, N.3
Ramponi, G.4
Dobson, C.M.5
-
16
-
-
33845978790
-
Insight into the Structure of Amyloid Fibrils from the Analysis of Globular Proteins
-
Trovato, A.; Chiti, F.; Maritan, A.; Seno, F. Insight into the Structure of Amyloid Fibrils from the Analysis of Globular Proteins PLOS Comput. Biol. 2006, 2, 1608-1618
-
(2006)
PLOS Comput. Biol.
, vol.2
, pp. 1608-1618
-
-
Trovato, A.1
Chiti, F.2
Maritan, A.3
Seno, F.4
-
17
-
-
5044235541
-
Prediction of Sequence-Dependent and Mutational Effects on the Aggregation of Peptides and Proteins
-
Fernandez-Escamilla, A. M.; Rousseau, F.; Schymkowitz, J.; Serrano, L. Prediction of Sequence-Dependent and Mutational Effects on the Aggregation of Peptides and Proteins Nat. Biotechnol. 2004, 22, 1302-1306
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 1302-1306
-
-
Fernandez-Escamilla, A.M.1
Rousseau, F.2
Schymkowitz, J.3
Serrano, L.4
-
18
-
-
44949219079
-
Prediction of Aggregation-Prone Regions in Structured Proteins
-
Tartaglia, G. G.; Pawar, A. P.; Campioni, S.; Dobson, C. M.; Chiti, F.; Vendruscolo, M. Prediction of Aggregation-Prone Regions in Structured Proteins J. Mol. Biol. 2008, 380, 425-436
-
(2008)
J. Mol. Biol.
, vol.380
, pp. 425-436
-
-
Tartaglia, G.G.1
Pawar, A.P.2
Campioni, S.3
Dobson, C.M.4
Chiti, F.5
Vendruscolo, M.6
-
19
-
-
84883140558
-
Modelling Amyloid Fibril Formation Kinetics: Mechanisms of Nucleation and Growth
-
Gillam, J. E.; Macphee, C. E. Modelling Amyloid Fibril Formation Kinetics: Mechanisms of Nucleation and Growth J. Phys.: Condens. Matter 2013, 25, 373101
-
(2013)
J. Phys.: Condens. Matter
, vol.25
, pp. 373101
-
-
Gillam, J.E.1
MacPhee, C.E.2
-
20
-
-
84863981137
-
From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation
-
Cohen, S. I. A.; Vendruscolo, M.; Dobson, C. M.; Knowles, T. P. J. From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation J. Mol. Biol. 2012, 421, 160-171
-
(2012)
J. Mol. Biol.
, vol.421
, pp. 160-171
-
-
Cohen, S.I.A.1
Vendruscolo, M.2
Dobson, C.M.3
Knowles, T.P.J.4
-
21
-
-
59349083966
-
Protein Aggregation Kinetics, Mechanism, and Curve-Fitting: A Review of the Literature
-
Morris, A. M.; Watzky, M. A.; Finke, R. G. Protein Aggregation Kinetics, Mechanism, And Curve-Fitting: A Review of the Literature Biochim. Biophys. Acta, Proteins Proteomics 2009, 1794, 375-397
-
(2009)
Biochim. Biophys. Acta, Proteins Proteomics
, vol.1794
, pp. 375-397
-
-
Morris, A.M.1
Watzky, M.A.2
Finke, R.G.3
-
22
-
-
79960698583
-
Amyloid Fibrillation Kinetics: Insight from Atomistic Nucleation Theory
-
Cabriolu, R.; Auer, S. Amyloid Fibrillation Kinetics: Insight from Atomistic Nucleation Theory J. Mol. Biol. 2011, 411, 275-285
-
(2011)
J. Mol. Biol.
, vol.411
, pp. 275-285
-
-
Cabriolu, R.1
Auer, S.2
-
23
-
-
84873025905
-
Aggregate Geometry in Amyloid Fibril Nucleation
-
Irback, A.; Jonsson, S. A. E.; Linnemann, N.; Linse, B.; Wallin, S. Aggregate Geometry in Amyloid Fibril Nucleation Phys. Rev. Lett. 2013, 110, 058101
-
(2013)
Phys. Rev. Lett.
, vol.110
, pp. 058101
-
-
Irback, A.1
Jonsson, S.A.E.2
Linnemann, N.3
Linse, B.4
Wallin, S.5
-
24
-
-
58749109622
-
Simulations of Nucleation and Elongation of Amyloid Fibrils
-
Zhang, J. N.; Muthukumar, M. Simulations of Nucleation and Elongation of Amyloid Fibrils J. Chem. Phys. 2009, 130, 035102
-
(2009)
J. Chem. Phys.
, vol.130
, pp. 035102
-
-
Zhang, J.N.1
Muthukumar, M.2
-
25
-
-
84865694928
-
Two-Step Nucleation of Amyloid Fibrils: Omnipresent or Not?
-
Auer, S.; Ricchiuto, P.; Kashchiev, D. Two-Step Nucleation of Amyloid Fibrils: Omnipresent or Not? J. Mol. Biol. 2012, 422, 723-730
-
(2012)
J. Mol. Biol.
, vol.422
, pp. 723-730
-
-
Auer, S.1
Ricchiuto, P.2
Kashchiev, D.3
-
26
-
-
80855156829
-
Phase diagram of polypeptide chains
-
Auer, S. Phase diagram of polypeptide chains J. Chem. Phys. 2011, 135, 175103
-
(2011)
J. Chem. Phys.
, vol.135
, pp. 175103
-
-
Auer, S.1
-
27
-
-
0029376152
-
The Interaction Energy between 2 Protein Molecules Related to Physical-Properties of Their Solution and Their Crystals and Implications for Crystal-Growth
-
Haas, C.; Drenth, J. The Interaction Energy between 2 Protein Molecules Related to Physical-Properties of Their Solution and Their Crystals and Implications for Crystal-Growth J. Cryst. Growth 1995, 154, 126135
-
(1995)
J. Cryst. Growth
, vol.154
, pp. 126135
-
-
Haas, C.1
Drenth, J.2
-
28
-
-
0035834113
-
Hierarchical Self-Assembly of Chiral Rod-Like Molecules as a Model for Peptide β-Sheet Tapes, Ribbons, Fibrils, and Fibers
-
Aggeli, A.; Nyrkova, I. A.; Bell, M.; Harding, R.; Carrick, L.; McLeish, T. C. B.; Semenov, A. N.; Boden, N. Hierarchical Self-Assembly of Chiral Rod-Like Molecules as a Model for Peptide β-Sheet Tapes, Ribbons, Fibrils, And Fibers Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 11857-11862
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 11857-11862
-
-
Aggeli, A.1
Nyrkova, I.A.2
Bell, M.3
Harding, R.4
Carrick, L.5
McLeish, T.C.B.6
Semenov, A.N.7
Boden, N.8
-
29
-
-
34547227879
-
Kinetics and Thermodynamics of Amyloid Formation from Direct Measurements of Fluctuations in Fibril Mass
-
Knowles, T. P. J.; Shu, W. M.; Devlin, G. L.; Meehan, S.; Auer, S.; Dobson, C. M.; Welland, M. E. Kinetics and Thermodynamics of Amyloid Formation from Direct Measurements of Fluctuations in Fibril Mass Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 10016-10021
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 10016
-
-
Knowles, T.P.J.1
Shu, W.M.2
Devlin, G.L.3
Meehan, S.4
Auer, S.5
Dobson, C.M.6
Welland, M.E.7
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