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Volumn 16, Issue 2, 2014, Pages 510-516

Altered cerebrospinal fluid levels of amyloid β and amyloid precursor-like protein 1 peptides in Down's syndrome

Author keywords

Amyloid precursor like protein 1; Amyloid ; Cerebrospinal fluid; Down's syndrome; Mass spectrometry

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-28]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR LIKE PROTEIN 1 BETA 25; AMYLOID PRECURSOR LIKE PROTEIN 1 BETA 27; AMYLOID PRECURSOR LIKE PROTEIN 1 BETA 28; AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN 1; PLASMIN; UNCLASSIFIED DRUG; AMYLOID BETA-PROTEIN (1-28); AMYLOID BETA-PROTEIN (1-42); APLP1 PROTEIN, HUMAN; BIOLOGICAL MARKER; PEPTIDE FRAGMENT;

EID: 84901259327     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-014-8302-1     Document Type: Article
Times cited : (28)

References (26)
  • 1
    • 33947391218 scopus 로고    scopus 로고
    • Cerebrospinal fluid protein reactions during non-neurological surgery
    • 10.1111/j.1600-0404.2006.00741.x 1:STN:280:DC%2BD2s7ns1emsw%3D%3D 17376123 10.1111/j.1600-0404.2006.00741.x
    • Anckarsater, R., Vasic, N., Jideus, L., Kristiansson, M., Zetterberg, H., Blennow, K., et al. (2007). Cerebrospinal fluid protein reactions during non-neurological surgery. Acta Neurologica Scandinavica, 115(4), 254-259. doi: 10.1111/j.1600-0404.2006.00741.x.
    • (2007) Acta Neurologica Scandinavica , vol.115 , Issue.4 , pp. 254-259
    • Anckarsater, R.1    Vasic, N.2    Jideus, L.3    Kristiansson, M.4    Zetterberg, H.5    Blennow, K.6
  • 2
    • 36348934620 scopus 로고    scopus 로고
    • Aspects of beta-amyloid as a biomarker for Alzheimer's disease
    • 10.2217/17520363.1.1.59 1:CAS:528:DC%2BD2sXosVartr4%3D 20477461 10.2217/17520363.1.1.59
    • Andreasson, U., Portelius, E., Andersson, M. E., Blennow, K., & Zetterberg, H. (2007). Aspects of beta-amyloid as a biomarker for Alzheimer's disease. Biomarkers in Medicine, 1(1), 59-78. doi: 10.2217/17520363.1.1.59.
    • (2007) Biomarkers in Medicine , vol.1 , Issue.1 , pp. 59-78
    • Andreasson, U.1    Portelius, E.2    Andersson, M.E.3    Blennow, K.4    Zetterberg, H.5
  • 3
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • 1:CAS:528:DC%2BD28XnsFymsbY%3D 16876668 10.1016/S0140-6736(06)69113-7
    • Blennow, K., de Leon, M. J., & Zetterberg, H. (2006). Alzheimer's disease. Lancet, 368(9533), 387-403.
    • (2006) Lancet , vol.368 , Issue.9533 , pp. 387-403
    • Blennow, K.1    De Leon, M.J.2    Zetterberg, H.3
  • 4
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • 10.1038/nrneurol.2010.4 1:CAS:528:DC%2BC3cXivVGqtb0%3D 20157306 10.1038/nrneurol.2010.4
    • Blennow, K., Hampel, H., Weiner, M., & Zetterberg, H. (2010). Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nature Reviews. Neurology, 6(3), 131-144. doi: 10.1038/nrneurol.2010.4.
    • (2010) Nature Reviews. Neurology , vol.6 , Issue.3 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 5
    • 84868516038 scopus 로고    scopus 로고
    • Safety and tolerability of the gamma-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease
    • 10.1001/archneurol.2012.2194 22892585 10.1001/archneurol.2012.2194
    • Coric, V., van Dyck, C. H., Salloway, S., Andreasen, N., Brody, M., Richter, R. W., et al. (2012). Safety and tolerability of the gamma-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease. Archives of Neurology, 69(11), 1430-1440. doi: 10.1001/archneurol.2012.2194.
    • (2012) Archives of Neurology , vol.69 , Issue.11 , pp. 1430-1440
    • Coric, V.1    Van Dyck, C.H.2    Salloway, S.3    Andreasen, N.4    Brody, M.5    Richter, R.W.6
  • 6
    • 0023132387 scopus 로고
    • Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
    • 1:CAS:528:DyaL2sXhtlaru70%3D 3810169 10.1126/science.3810169
    • Goldgaber, D., Lerman, M. I., McBride, O. W., Saffiotti, U., & Gajdusek, D. C. (1987). Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science, 235(4791), 877-880.
    • (1987) Science , vol.235 , Issue.4791 , pp. 877-880
    • Goldgaber, D.1    Lerman, M.I.2    McBride, O.W.3    Saffiotti, U.4    Gajdusek, D.C.5
  • 7
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
    • 1:CAS:528:DyaL2sXktVWkt7s%3D 2881207 10.1038/325733a0
    • Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., et al. (1987). The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature, 325(6106), 733-736.
    • (1987) Nature , vol.325 , Issue.6106 , pp. 733-736
    • Kang, J.1    Lemaire, H.G.2    Unterbeck, A.3    Salbaum, J.M.4    Masters, C.L.5    Grzeschik, K.H.6
  • 8
    • 80052266213 scopus 로고    scopus 로고
    • The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics
    • 10.1038/nrd3505 1:CAS:528:DC%2BC3MXhtVelsL3L 21852788 10.1038/nrd3505
    • Karran, E., Mercken, M., & De Strooper, B. (2011). The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics. Nature Reviews. Drug Discovery, 10(9), 698-712. doi: 10.1038/nrd3505.
    • (2011) Nature Reviews. Drug Discovery , vol.10 , Issue.9 , pp. 698-712
    • Karran, E.1    Mercken, M.2    De Strooper, B.3
  • 9
    • 0034573026 scopus 로고    scopus 로고
    • Brain plasmin enhances APPα-cleavage and Aβ degradation and is reduced in Alzheimer's disease brains
    • 10.1093/embo-reports/kvd107 1:CAS:528:DC%2BD3MXjt1ejtbY%3D 1083779 11263499 10.1093/embo-reports/kvd107
    • Ledesma, M. D., Da Silva, J. S., Crassaerts, K., Delacourte, A., De Strooper, B., & Dotti, C. G. (2000). Brain plasmin enhances APPα-cleavage and Aβ degradation and is reduced in Alzheimer's disease brains. EMBO Reports, 1(6), 530-535. doi: 10.1093/embo-reports/kvd107.
    • (2000) EMBO Reports , vol.1 , Issue.6 , pp. 530-535
    • Ledesma, M.D.1    Da Silva, J.S.2    Crassaerts, K.3    Delacourte, A.4    De Strooper, B.5    Dotti, C.G.6
  • 10
    • 17544399111 scopus 로고    scopus 로고
    • Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: A regional quantitative analysis
    • 10.1006/exnr.1997.6777 1:STN:280:DyaK1c7pslWntg%3D%3D 9527899 10.1006/exnr.1997.6777
    • Leverenz, J. B., & Raskind, M. A. (1998). Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis. Experimental Neurology, 150(2), 296-304. doi: 10.1006/exnr.1997.6777.
    • (1998) Experimental Neurology , vol.150 , Issue.2 , pp. 296-304
    • Leverenz, J.B.1    Raskind, M.A.2
  • 11
    • 0038268072 scopus 로고    scopus 로고
    • The amyloid-β (Aβ) peptide pattern in cerebrospinal fluid in Alzheimer's disease: Evidence of a novel carboxyterminally elongated Aβ peptide
    • 1:CAS:528:DC%2BD3sXltFalsL0%3D 12811752 10.1002/rcm.1048
    • Lewczuk, P., Esselmann, H., Meyer, M., Wollscheid, V., Neumann, M., Otto, M., et al. (2003). The amyloid-β (Aβ) peptide pattern in cerebrospinal fluid in Alzheimer's disease: Evidence of a novel carboxyterminally elongated Aβ peptide. Rapid Communications in Mass Spectrometry, 17(12), 1291-1296.
    • (2003) Rapid Communications in Mass Spectrometry , vol.17 , Issue.12 , pp. 1291-1296
    • Lewczuk, P.1    Esselmann, H.2    Meyer, M.3    Wollscheid, V.4    Neumann, M.5    Otto, M.6
  • 12
    • 84856638194 scopus 로고    scopus 로고
    • BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system
    • 10.1371/journal.pone.0031084 1:CAS:528:DC%2BC38XisFyrt7w%3D 3273469 22328928 10.1371/journal.pone.0031084
    • Mattsson, N., Rajendran, L., Zetterberg, H., Gustavsson, M., Andreasson, U., Olsson, M., et al. (2012). BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system. PLoS One, 7(2), e31084. doi: 10.1371/journal.pone.0031084.
    • (2012) PLoS One , vol.7 , Issue.2 , pp. 31084
    • Mattsson, N.1    Rajendran, L.2    Zetterberg, H.3    Gustavsson, M.4    Andreasson, U.5    Olsson, M.6
  • 13
    • 76749167709 scopus 로고    scopus 로고
    • Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease
    • 10.1186/1750-1326-5-2 2818651 20145736 10.1186/1750-1326-5-2
    • Portelius, E., Andreasson, U., Ringman, J. M., Buerger, K., Daborg, J., Buchhave, P., et al. (2010a). Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease. Molecular Neurodegeneration, 5, 2. doi: 10.1186/1750-1326-5-2.
    • (2010) Molecular Neurodegeneration , vol.5 , pp. 2
    • Portelius, E.1    Andreasson, U.2    Ringman, J.M.3    Buerger, K.4    Daborg, J.5    Buchhave, P.6
  • 14
    • 77953418604 scopus 로고    scopus 로고
    • A novel Aβ isoform pattern in CSF reflects γ-secretase inhibition in Alzheimer disease
    • 10.1186/alzrt30 2876785 20350302 10.1186/alzrt30
    • Portelius, E., Dean, R. A., Gustavsson, M. K., Andreasson, U., Zetterberg, H., Siemers, E., et al. (2010b). A novel Aβ isoform pattern in CSF reflects γ-secretase inhibition in Alzheimer disease. Alzheimer's Research and Therapy, 2(2), 7. doi: 10.1186/alzrt30.
    • (2010) Alzheimer's Research and Therapy , vol.2 , Issue.2 , pp. 7
    • Portelius, E.1    Dean, R.A.2    Gustavsson, M.K.3    Andreasson, U.4    Zetterberg, H.5    Siemers, E.6
  • 15
    • 80053309666 scopus 로고    scopus 로고
    • Novel Aβ isoforms in Alzheimer's disease - Their role in diagnosis and treatment
    • 1:CAS:528:DC%2BC3MXhsVSis7rO 21728980 10.2174/138161211797416039
    • Portelius, E., Mattsson, N., Andreasson, U., Blennow, K., & Zetterberg, H. (2011a). Novel Aβ isoforms in Alzheimer's disease - their role in diagnosis and treatment. Current Pharmaceutical Design, 17(25), 2594-2602.
    • (2011) Current Pharmaceutical Design , vol.17 , Issue.25 , pp. 2594-2602
    • Portelius, E.1    Mattsson, N.2    Andreasson, U.3    Blennow, K.4    Zetterberg, H.5
  • 16
    • 79955953179 scopus 로고    scopus 로고
    • A novel pathway for amyloid precursor protein processing
    • 10.1016/j.neurobiolaging.2009.06.002 1:CAS:528:DC%2BC3MXmsVGiu7g%3D 19604603 10.1016/j.neurobiolaging.2009.06.002
    • Portelius, E., Price, E., Brinkmalm, G., Stiteler, M., Olsson, M., Persson, R., et al. (2011b). A novel pathway for amyloid precursor protein processing. Neurobiology of Aging, 32(6), 1090-1098. doi: 10.1016/j. neurobiolaging.2009.06.002.
    • (2011) Neurobiology of Aging , vol.32 , Issue.6 , pp. 1090-1098
    • Portelius, E.1    Price, E.2    Brinkmalm, G.3    Stiteler, M.4    Olsson, M.5    Persson, R.6
  • 18
    • 36348970121 scopus 로고    scopus 로고
    • Characterization of amyloid β peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry
    • 10.1021/pr0703627 1:CAS:528:DC%2BD2sXhtFegsrnE 17927230 10.1021/pr0703627
    • Portelius, E., Tran, A. J., Andreasson, U., Persson, R., Brinkmalm, G., Zetterberg, H., et al. (2007). Characterization of amyloid β peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry. Journal of Proteome Research, 6(11), 4433-4439. doi: 10.1021/pr0703627.
    • (2007) Journal of Proteome Research , vol.6 , Issue.11 , pp. 4433-4439
    • Portelius, E.1    Tran, A.J.2    Andreasson, U.3    Persson, R.4    Brinkmalm, G.5    Zetterberg, H.6
  • 19
    • 0031939059 scopus 로고    scopus 로고
    • Molecular mapping of Alzheimer-type dementia in Down's syndrome
    • 10.1002/ana.410430316 1:CAS:528:DyaK1cXitFart7g%3D 9506555 10.1002/ana.410430316
    • Prasher, V. P., Farrer, M. J., Kessling, A. M., Fisher, E. M., West, R. J., Barber, P. C., et al. (1998). Molecular mapping of Alzheimer-type dementia in Down's syndrome. Annals of Neurology, 43(3), 380-383. doi: 10.1002/ana.410430316.
    • (1998) Annals of Neurology , vol.43 , Issue.3 , pp. 380-383
    • Prasher, V.P.1    Farrer, M.J.2    Kessling, A.M.3    Fisher, E.M.4    West, R.J.5    Barber, P.C.6
  • 20
    • 84869126018 scopus 로고    scopus 로고
    • Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: A case-control study
    • 10.1016/S1474-4422(12)70228-4 1:CAS:528:DC%2BC38Xhs12gt7%2FN 23137948 10.1016/S1474-4422(12)70228-4
    • Reiman, E. M., Quiroz, Y. T., Fleisher, A. S., Chen, K., Velez-Pardo, C., Jimenez-Del-Rio, M., et al. (2012). Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: A case-control study. Lancet Neurology, 11(12), 1048-1056. doi: 10.1016/S1474-4422(12)70228-4.
    • (2012) Lancet Neurology , vol.11 , Issue.12 , pp. 1048-1056
    • Reiman, E.M.1    Quiroz, Y.T.2    Fleisher, A.S.3    Chen, K.4    Velez-Pardo, C.5    Jimenez-Del-Rio, M.6
  • 21
    • 0345072510 scopus 로고    scopus 로고
    • Amyloid beta protein species in cerebrospinal fluid and in brain from patients with Down's syndrome
    • 1:STN:280:DC%2BD3c%2FlsFCltQ%3D%3D 10589550 10.1002/1531-8249(199912)46: 6<933: AID-ANA20>3.0.CO;2-4
    • Tamaoka, A., Sekijima, Y., Matsuno, S., Tokuda, T., Shoji, S., & Ikeda, S. I. (1999). Amyloid beta protein species in cerebrospinal fluid and in brain from patients with Down's syndrome. Annals of Neurology, 46(6), 933.
    • (1999) Annals of Neurology , vol.46 , Issue.6 , pp. 933
    • Tamaoka, A.1    Sekijima, Y.2    Matsuno, S.3    Tokuda, T.4    Shoji, S.5    Ikeda, S.I.6
  • 22
    • 0035836622 scopus 로고    scopus 로고
    • CSF tau and Aβ42 levels in patients with Down's syndrome
    • 1:CAS:528:DC%2BD3MXjsFSnsL4%3D 11294944 10.1212/WNL.56.7.979
    • Tapiola, T., Soininen, H., & Pirttila, T. (2001). CSF tau and Aβ42 levels in patients with Down's syndrome. Neurology, 56(7), 979-980.
    • (2001) Neurology , vol.56 , Issue.7 , pp. 979-980
    • Tapiola, T.1    Soininen, H.2    Pirttila, T.3
  • 23
    • 18544410708 scopus 로고    scopus 로고
    • The plasmin system is induced by and degrades amyloid-β aggregates
    • 1:CAS:528:DC%2BD3cXjsFeltLo%3D 10818128
    • Tucker, H. M., Kihiko, M., Caldwell, J. N., Wright, S., Kawarabayashi, T., Price, D., et al. (2000). The plasmin system is induced by and degrades amyloid-β aggregates. Journal of Neuroscience, 20(11), 3937-3946.
    • (2000) Journal of Neuroscience , vol.20 , Issue.11 , pp. 3937-3946
    • Tucker, H.M.1    Kihiko, M.2    Caldwell, J.N.3    Wright, S.4    Kawarabayashi, T.5    Price, D.6
  • 24
    • 0033621048 scopus 로고    scopus 로고
    • Plasmin cleavage of the amyloid β-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity
    • 10471309 10.1021/bi990610f
    • Van Nostrand, W. E., & Porter, M. (1999). Plasmin cleavage of the amyloid β-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity. Biochemistry, 38(35), 11570-11576.
    • (1999) Biochemistry , vol.38 , Issue.35 , pp. 11570-11576
    • Van Nostrand, W.E.1    Porter, M.2
  • 25
    • 0027499514 scopus 로고
    • The amyloid precursor-like protein (APLP) gene maps to the long arm of human chromosome 19
    • 10.1006/geno.1993.1047 1:CAS:528:DyaK3sXkt1Wrt7c%3D 8432545 10.1006/geno.1993.1047
    • Wasco, W., Brook, J. D., & Tanzi, R. E. (1993). The amyloid precursor-like protein (APLP) gene maps to the long arm of human chromosome 19. Genomics, 15(1), 237-239. doi: 10.1006/geno.1993.1047.
    • (1993) Genomics , vol.15 , Issue.1 , pp. 237-239
    • Wasco, W.1    Brook, J.D.2    Tanzi, R.E.3
  • 26
    • 72749122106 scopus 로고    scopus 로고
    • The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system
    • 10.1002/emmm.200900026 1:CAS:528:DC%2BD1MXht1CjurrP 3378133 20049724 10.1002/emmm.200900026
    • Yanagida, K., Okochi, M., Tagami, S., Nakayama, T., Kodama, T. S., Nishitomi, K., et al. (2009). The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system. EMBO Mol Med, 1(4), 223-235. doi: 10.1002/emmm. 200900026.
    • (2009) EMBO Mol Med , vol.1 , Issue.4 , pp. 223-235
    • Yanagida, K.1    Okochi, M.2    Tagami, S.3    Nakayama, T.4    Kodama, T.S.5    Nishitomi, K.6


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