Low pepsinogen I level predicts multiple gastric epithelial neoplasias for endoscopic resection

Gut and Liver

Volumn 8, Issue 3, 2014, Pages 277-281

  Park, Seon Young ^a   Lim, Sung Ook ^a   Ki, Ho Seok ^a   Jun, Chung Hwan ^a   Park, Chang Hwan ^a   Kim, Hyun Soo ^a   Choi, Sung Kyu ^a   Rew, Jong Sun ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Neoplasms; Pepsinogens; Stomach

Indexed keywords

PEPSINOGEN I; PEPSINOGEN II; PEPSINOGEN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; ENDOSCOPIC SUBMUCOSAL DISSECTION; ENZYME BLOOD LEVEL; FEMALE; GASTRIC EPITHELIAL NEOPLASIA; GASTROINTESTINAL ENDOSCOPY; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PREDICTIVE VALUE; STOMACH CANCER; TUMOR VOLUME; DEFICIENCY; GASTROSCOPY; NEOPLASMS, GLANDULAR AND EPITHELIAL; NEOPLASMS, MULTIPLE PRIMARY; RETROSPECTIVE STUDY; STOMACH NEOPLASMS;

FEMALE; GASTROSCOPY; HUMANS; MALE; MIDDLE AGED; NEOPLASMS, GLANDULAR AND EPITHELIAL; NEOPLASMS, MULTIPLE PRIMARY; PEPSINOGEN A; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS;

EID: 84901238018     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl.2014.8.3.277     Document Type: Article

References (20)

1. Nasu J, Doi T, Endo H, Nishina T, Hirasaki S, Hyodo I. Characteristics of metachronous multiple early gastric cancers after endoscopic mucosal resection. Endoscopy 2005;37:990-993. (Pubitemid 41489269)
2. Arima N, Adachi K, Katsube T, et al. Predictive factors for metachronous recurrence of early gastric cancer after endoscopic treatment. J Clin Gastroenterol 1999;29:44-47. (Pubitemid 29288202)
3. Uemura N, Mukai T, Okamoto S, et al. Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic resection of early gastric cancer. Cancer Epidemiol Biomarkers Prev 1997;6:639-642. (Pubitemid 27342688)
4. Kikuchi S, Kato M, Katsuyama T, Tominaga S, Asaka M. Design and planned analyses of an ongoing randomized trial assessing the preventive effect of Helicobacter pylori eradication on occurrence of new gastric carcinomas after endoscopic resection. Helicobacter 2006;11:147-151. (Pubitemid 43736548)
5. Kato M, Asaka M, Shimizu Y, et al. Relationship between Helicobacter pylori infection and the prevalence, site and histological type of gastric cancer. Aliment Pharmacol Ther 2004;20 Suppl 1:85-89. (Pubitemid 39120277)
6. Fukase K, Kato M, Kikuchi S, et al. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet 2008;372:392-397.
7. Kim SG. Endoscopic treatment for early gastric cancer. J Gastric Cancer 2011;11:146-154.
8. Samloff IM. Cellular localization of group I pepsinogens in human gastric mucosa by immunofluorescence. Gastroenterology 1971;61:185-188.
9. Samloff IM, Liebman WM. Cellular localization of the group II pepsinogens in human stomach and duodenum by immunofluorescence. Gastroenterology 1973;65:36-42.
10. Varis K, Sipponen P, Laxén F, et al. Implications of serum pepsinogen I in early endoscopic diagnosis of gastric cancer and dysplasia: Helsinki Gastritis Study Group. Scand J Gastroenterol 2000;35:950-956.
11. Correa P. A human model of gastric carcinogenesis. Cancer Res 1988;48:3554-3560.
12. Filipe MI, Muñoz N, Matko I, et al. Intestinal metaplasia types and the risk of gastric cancer: a cohort study in Slovenia. Int J Cancer 1994;57:324-329. (Pubitemid 24168604)
13. Schlemper RJ, Riddell RH, Kato Y, et al. The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000;47:251-255. (Pubitemid 30489769)
14. Kikuchi R, Abe Y, Iijima K, et al. Low serum levels of pepsinogen and gastrin 17 are predictive of extensive gastric atrophy with high-risk of early gastric cancer. Tohoku J Exp Med 2011;223:35-44.
15. Fahey MT, Hamada GS, Nishimoto IN, et al. Ethnic differences in serum pepsinogen levels among Japanese and non-Japanese Brazilian gastric cancer patients and controls. Cancer Detect Prev 2000;24:564-571. (Pubitemid 32099843)
16. Kato I, Miki K, Muñoz N, et al. Determinants of plasma pepsinogen levels in a population at high risk for stomach cancer in Venezuela. Int J Cancer 1995;62:512-518.
17. Shiotani A, Uedo N, Iishi H, et al. Predictive factors for metachronous gastric cancer in high-risk patients after successful Helicobacter pylori eradication. Digestion 2008;78:113-119.
18. Miyoshi E, Haruma K, Hiyama T, et al. Microsatellite instability is a genetic marker for the development of multiple gastric cancers. Int J Cancer 2001;95:350-353. (Pubitemid 33015103)
19. Hasuo T, Semba S, Li D, et al. Assessment of microsatellite instability status for the prediction of metachronous recurrence after initial endoscopic submucosal dissection for early gastric cancer. Br J Cancer 2007;96:89-94. (Pubitemid 46094644)
20. Hanaoka N, Uedo N, Shiotani A, et al. Autofluorescence imaging for predicting development of metachronous gastric cancer after Helicobacter pylori eradication. J Gastroenterol Hepatol 2010;25:1844-1849.