-
1
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor, J. P., Hardy, J., & Fischbeck, K. H. (2002). Toxic proteins in neurodegenerative disease. Science, 296, 1991-1995.
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
2
-
-
33745195252
-
The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
-
Ellisdon, A. M., Thomas, B., & Bottomley, S. P. (2006). The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step. Journal of Biological Chemistry, 281, 16888-16896.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 16888-16896
-
-
Ellisdon, A.M.1
Thomas, B.2
Bottomley, S.P.3
-
3
-
-
64049119303
-
Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
-
Thakur, A. K., Jayaraman, M., Mishra, R., Thakur, M., Chellgren, V. M., Byeon, I. J., et al. (2009). Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nature Structural & Molecular Biology, 16, 380-389.
-
(2009)
Nature Structural & Molecular Biology
, vol.16
, pp. 380-389
-
-
Thakur, A.K.1
Jayaraman, M.2
Mishra, R.3
Thakur, M.4
Chellgren, V.M.5
Byeon, I.J.6
Anjum, D.H.7
Kodali, R.8
Creamer, T.P.9
Conway, J.F.10
Gronenborn, A.M.11
Wetzel, R.12
-
4
-
-
18944394158
-
The AXH domain adopts alternative folds the solution structure of HBP1 AXH
-
de Chiara, C., Menon, R. P., Adinolfi, S., de Boer, J., Ktistaki, E., Kelly, G., et al. (2005). The AXH domain adopts alternative folds the solution structure of HBP1 AXH. Structure, 13, 743-753.
-
(2005)
Structure
, vol.13
, pp. 743-753
-
-
de Chiara, C.1
Menon, R.P.2
Adinolfi, S.3
de Boer, J.4
Ktistaki, E.5
Kelly, G.6
Calder, L.7
Kioussis, D.8
Pastore, A.9
-
7
-
-
0036306310
-
Monodisperse Hsp16.3 nonamer exhibits dynamic dissociation and reassociation, with the nonamer dissociation prerequisite for chaperone-like activity
-
Gu, L., Abulimiti, A., Li, W., & Chang, Z. J. (2002). Monodisperse Hsp16. 3 nonamer exhibits dynamic dissociation and reassociation, with the nonamer dissociation prerequisite for chaperone-like activity. Journal of Molecular Biology, 319, 517-526.
-
(2002)
Journal of Molecular Biology
, vol.319
, pp. 517-526
-
-
Gu, L.1
Abulimiti, A.2
Li, W.3
Chang, Z.J.4
-
8
-
-
37449009967
-
Structure and orientation of T4 lysozyme bound to the small heat shock protein alpha-crystallin
-
Claxton, D. P., Zou, P., & Mchaourab, H. S. (2008). Structure and orientation of T4 lysozyme bound to the small heat shock protein alpha-crystallin. Journal of Molecular Biology, 375, 1026-1039.
-
(2008)
Journal of Molecular Biology
, vol.375
, pp. 1026-1039
-
-
Claxton, D.P.1
Zou, P.2
Mchaourab, H.S.3
-
9
-
-
34548241302
-
Interactive sequences in the stress protein and molecular chaperone human alphaB crystallin recognize and modulate the assembly of filaments
-
Ghosh, J. G., Houck, S. A., & Clark, J. I. (2007). Interactive sequences in the stress protein and molecular chaperone human alphaB crystallin recognize and modulate the assembly of filaments. International Journal of Biochemistry & Cell Biology, 39, 1804-1815.
-
(2007)
International Journal of Biochemistry & Cell Biology
, vol.39
, pp. 1804-1815
-
-
Ghosh, J.G.1
Houck, S.A.2
Clark, J.I.3
-
10
-
-
35949001344
-
Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila
-
Bilen, J., & Bonini, N. M. (2007). Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila. PLoS Genetics, 3, 1950-1964.
-
(2007)
PLoS Genetics
, vol.3
, pp. 1950-1964
-
-
Bilen, J.1
Bonini, N.M.2
-
11
-
-
77953799932
-
Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation
-
Robertson, A. L., Headeyb, S. J., Saunders, H. M., Ecroyd, H., Scanlon, H. M., Carver, J. A., et al. (2010). Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation. Proceedings of the National Academy of Sciences of the USA, 107, 10424-10429.
-
(2010)
Proceedings of the National Academy of Sciences of the USA
, vol.107
, pp. 10424-10429
-
-
Robertson, A.L.1
Headeyb, S.J.2
Saunders, H.M.3
Ecroyd, H.4
Scanlon, H.M.5
Carver, J.A.6
Bottomley, S.P.7
-
13
-
-
69249240169
-
Tyrosine kinase inhibition: Ligand binding and conformational change in c-Kit and c-Abl
-
Healy, E. F., Johnson, S., Hauser, C., & King, P. (2009). Tyrosine kinase inhibition: Ligand binding and conformational change in c-Kit and c-Abl. Federation of European Biochemical Societies Letters, 583, 2899-2906.
-
(2009)
Federation of European Biochemical Societies Letters
, vol.583
, pp. 2899-2906
-
-
Healy, E.F.1
Johnson, S.2
Hauser, C.3
King, P.4
-
14
-
-
84855303488
-
The effect of desolvation on nucleophilic halogenase activity
-
Healy, E. F. (2011). The effect of desolvation on nucleophilic halogenase activity. Computational and Theoretical Chemistry, 964, 91-93.
-
(2011)
Computational and Theoretical Chemistry
, vol.964
, pp. 91-93
-
-
Healy, E.F.1
-
15
-
-
78649528785
-
Acetylenic inhibitors of ADAM10 and ADAM17: In silico analysis of potency and selectivity
-
Healy, E. F., Romano, P., Mejia, M., & Lindfors, G, I. I. I. (2010). Acetylenic inhibitors of ADAM10 and ADAM17: In silico analysis of potency and selectivity. Journal of Molecular Graphics and Modelling, 29, 436-442.
-
(2010)
Journal of Molecular Graphics and Modelling
, vol.29
, pp. 436-442
-
-
Healy, E.F.1
Romano, P.2
Mejia, M.3
Lindfors III, G.4
-
16
-
-
0041821388
-
Dehydron: A structure-encoded signal for protein interactions
-
Fernández, A., & Ridgway, S. (2003). Dehydron: A structure-encoded signal for protein interactions. Biophysical Journal, 85, 1914-1928.
-
(2003)
Biophysical Journal
, vol.85
, pp. 1914-1928
-
-
Fernández, A.1
Ridgway, S.2
-
17
-
-
33751250818
-
Feature-similarity protein classifier as a ligand engineering tool
-
Maddipati, S., & Fernández, A. (2006). Feature-similarity protein classifier as a ligand engineering tool. Biomolecular Engineering, 23, 307-315.
-
(2006)
Biomolecular Engineering
, vol.23
, pp. 307-315
-
-
Maddipati, S.1
Fernández, A.2
-
18
-
-
79959543603
-
Nature non-adaptive origins of interactome complexity
-
Fernández, A., & Lynch, M. (2011). Nature non-adaptive origins of interactome complexity. Nature, 474, 502-505.
-
(2011)
Nature
, vol.474
, pp. 502-505
-
-
Fernández, A.1
Lynch, M.2
-
20
-
-
84859599030
-
A model for heterooligomer formation in the heat shock response of Escherichia coli
-
Healy, E. F. (2012). A model for heterooligomer formation in the heat shock response of Escherichia coli. Biochemical and Biophysical Research Communications, 420, 639-643.
-
(2012)
Biochemical and Biophysical Research Communications
, vol.420
, pp. 639-643
-
-
Healy, E.F.1
-
21
-
-
84986512474
-
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
-
Brooks, B. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swaminathan, S., & Karplus, M. (1983). CHARMM: A program for macromolecular energy, minimization, and dynamics calculations. Journal of Computational Chemistry, 4, 187-217.
-
(1983)
Journal of Computational Chemistry
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccoleri, R.E.2
Olafson, B.D.3
States, D.J.4
Swaminathan, S.5
Karplus, M.6
-
22
-
-
23044515498
-
The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition
-
Nicastro, G., Menon, R. P., Masino, L., Knowles, P. P., McDonald, N. Q., & Pastore, A. (2005). The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition. Proceedings of the National Academy of Sciences of the USA, 102, 10493-10498.
-
(2005)
Proceedings of the National Academy of Sciences of the USA
, vol.102
, pp. 10493-10498
-
-
Nicastro, G.1
Menon, R.P.2
Masino, L.3
Knowles, P.P.4
McDonald, N.Q.5
Pastore, A.6
-
23
-
-
0038526303
-
ZDOCK: An initial-stage protein-docking algorithm
-
Chen, R., Li, L., & Weng, Z. (2003). ZDOCK: An initial-stage protein-docking algorithm. Proteins, 52, 80-87.
-
(2003)
Proteins
, vol.52
, pp. 80-87
-
-
Chen, R.1
Li, L.2
Weng, Z.3
-
24
-
-
34248513078
-
ZRANK: Reranking protein docking predictions with an optimized energy function
-
Pierce, B., & Weng, Z. (2007). ZRANK: Reranking protein docking predictions with an optimized energy function. Proteins-Structure Function and Genetics, 67, 1078-1086.
-
(2007)
Proteins-Structure Function and Genetics
, vol.67
, pp. 1078-1086
-
-
Pierce, B.1
Weng, Z.2
-
25
-
-
33947716119
-
A semiempirical free energy force field with charge-based desolvation
-
Huey, R., Morris, G. M., Olson, A. J., & Goodsell, D. S. (2007). A semiempirical free energy force field with charge-based desolvation. Journal of Computational Chemistry, 28, 1145-1152.
-
(2007)
Journal of Computational Chemistry
, vol.28
, pp. 1145-1152
-
-
Huey, R.1
Morris, G.M.2
Olson, A.J.3
Goodsell, D.S.4
-
26
-
-
84901207991
-
-
AutoDock Tools
-
AutoDock Tools [http://autodock. scripps. edu/resources/adt/index_html].
-
-
-
-
27
-
-
49149147973
-
Iterative partial equalization of orbital electronegativity-A rapid access to atomic charges
-
Gasteiger, J., & Marsili, M. (1980). Iterative partial equalization of orbital electronegativity-A rapid access to atomic charges. Tetrahedron, 36, 3219-3228.
-
(1980)
Tetrahedron
, vol.36
, pp. 3219-3228
-
-
Gasteiger, J.1
Marsili, M.2
-
28
-
-
11644261806
-
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
-
Morris, G. M., Goodsell, D. S., Halliday, R. S., Huey, R., Hart, W. E., Belew, R. K., et al. (1998). Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. Journal of Computational Chemistry, 19, 1639-1662.
-
(1998)
Journal of Computational Chemistry
, vol.19
, pp. 1639-1662
-
-
Morris, G.M.1
Goodsell, D.S.2
Halliday, R.S.3
Huey, R.4
Hart, W.E.5
Belew, R.K.6
Olson, A.J.7
-
29
-
-
0038425042
-
Proteins with H-bond packing defects are highly interactive with lipid bilayers: Implications for amyloidogenesis
-
Fernández, A., & Berry, R. S. (2003). Proteins with H-bond packing defects are highly interactive with lipid bilayers: Implications for amyloidogenesis. Proceedings of the National Academy of Sciences of the USA, 100, 2391-2396.
-
(2003)
Proceedings of the National Academy of Sciences of the USA
, vol.100
, pp. 2391-2396
-
-
Fernández, A.1
Berry, R.S.2
-
30
-
-
71449084004
-
The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
-
Tam, S., Spiess, C., Auyeung, W., Joachimiak, L., Chen, B., Poirier, M. A., et al. (2009). The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation. Nature Structural & Molecular Biology, 16, 1279-1285.
-
(2009)
Nature Structural & Molecular Biology
, vol.16
, pp. 1279-1285
-
-
Tam, S.1
Spiess, C.2
Auyeung, W.3
Joachimiak, L.4
Chen, B.5
Poirier, M.A.6
Frydman, J.7
-
31
-
-
74049108958
-
Protein folding: sticky N17 speeds huntingtin pile-up
-
Liebman, S. W., & Meredith, S. C. (2010). Protein folding: sticky N17 speeds huntingtin pile-up. Nature Chemical Biology, 6, 7-8.
-
(2010)
Nature Chemical Biology
, vol.6
, pp. 7-8
-
-
Liebman, S.W.1
Meredith, S.C.2
|