Biosynthesis and trafficking of the bile salt export pump, BSEP: Therapeutic implications of BSEP mutations

Molecular Aspects of Medicine

Volumn 37, Issue , 2014, Pages 3-14

  Soroka, Carol J ^a,b   Boyer, James L ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

ATP binding cassette transporter; Bile salt secretion; Cholestasis

Indexed keywords

4 PHENYLBUTYRIC ACID; AMINOGLYCOSIDE DERIVATIVE; ATALUREN; BILE ACID; BILE SALT EXPORT PUMP; ABC TRANSPORTER; ABCB11 PROTEIN, HUMAN;

ARTICLE; BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS TYPE 2; BSEP GENE; CELL MEMBRANE; CHOLESTASIS; DRUG INDUCED CHOLESTASIS; ENZYME REGULATION; FAT INTAKE; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; INTRAHEPATIC CHOLESTASIS OF PREGNANCY; MOLECULAR CLONING; NONHUMAN; PATHOPHYSIOLOGY; PLASMA HALF LIFE; PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS TYPE 2; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; TRANSCRIPTION REGULATION; BIOSYNTHESIS; FEMALE; GENETICS; HEPATOBILIARY SYSTEM; INTRAHEPATIC CHOLESTASIS; LIVER CELL; METABOLISM; MUTATION; PATHOLOGY; PREGNANCY;

ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; BILIARY TRACT; CHOLESTASIS, INTRAHEPATIC; FEMALE; HEPATOCYTES; HUMANS; MUTATION; PREGNANCY;

EID: 84901233961     PISSN: 00982997     EISSN: 18729452     Source Type: Journal    
DOI: 10.1016/j.mam.2013.05.001     Document Type: Article

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