Sizing up the poly(A) tail: Insights from deep sequencing

Trends in Biochemical Sciences

Volumn 39, Issue 6, 2014, Pages 255-257

  Zheng, Dinghai ^a   Tian, Bin ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

MRNA stability; Poly(A) tail; Polyadenylation; Post transcriptional control; Translation

Indexed keywords

POLYADENYLIC ACID; 3' UNTRANSLATED REGION; MESSENGER RNA;

3' UNTRANSLATED REGION; ACCURACY; ANIMAL CELL; ANIMAL TISSUE; GENE AND NUCLEIC ACID PARAMETERS; GENETIC ASSOCIATION; GENETIC REGULATION; GUANYLATION; HALF LIFE TIME; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUCLEOTIDE TAIL LENGTH; POLY(A) TAIL LENGTH; PRIORITY JOURNAL; RNA ANALYSIS; RNA DEGRADATION; RNA METABOLISM; RNA STABILITY; SEQUENCE ANALYSIS; SHORT SURVEY; TRANSLATION REGULATION; URIDYLATION; ANIMAL; GENETICS; HIGH THROUGHPUT SEQUENCING; RNA PROCESSING;

3' UNTRANSLATED REGIONS; ANIMALS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; POLY A; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

EID: 84901196875     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2014.04.002     Document Type: Short Survey

References (10)

1. Sachs A., Wahle E. Poly(A) tail metabolism and function in eucaryotes. J. Biol. Chem. 1993, 268:22955-22958.
2. Weill L., et al. Translational control by changes in poly(A) tail length: recycling mRNAs. Nat. Struct. Mol. Biol. 2012, 19:577-585.
3. Meijer H.A., et al. A novel method for poly(A) fractionation reveals a large population of mRNAs with a short poly(A) tail in mammalian cells. Nucleic Acids Res. 2007, 35:e132.
4. Beilharz T.H., Preiss T. Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome. RNA 2007, 13:982-997.
5. Quail M.A., et al. A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers. BMC Genomics 2012, 13:341.
6. Subtelny A.O., et al. Poly(A)-tail profiling reveals an embryonic switch in translational control. Nature 2014, 508:66-71.
7. Chang H., et al. TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3' End Modifications. Mol. Cell 2014, 53:1044-1052.
8. Chen C.Y., Shyu A.B. Mechanisms of deadenylation-dependent decay. Wiley Interdiscip. Rev. RNA 2011, 2:167-183.
9. Bazzini A.A., et al. Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish. Science 2012, 336:233-237.
10. Guo H., et al. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010, 466:835-840.