Transporter assays and assay ontologies: Useful tools for drug discovery

Drug Discovery Today: Technologies

Volumn 12, Issue , 2014, Pages

  Zdrazil, Barbara ^a   Chichester, Christine ^b   Zander Balderud, Linda ^c   Engkvist, Ola ^c   Gaulton, Anna ^d   Overington, John P ^d  

^a UNIVERSITY OF VIENNA   (Austria)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c ASTRAZENECA R AND D   (Sweden)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; DRUG;

ACTIVE TRANSPORT; ARTICLE; ATPASE ACTIVITY ASSAY; BIOASSAY; BIOLOGICAL ACTIVITY; DRUG ABSORPTION; DRUG DEVELOPMENT; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG TARGETING; DRUG TOXICITY; HIGH THROUGHPUT SCREENING; HUMAN; LIGAND BINDING; LIPID BILAYER; ONTOLOGY; PASSIVE TRANSPORT; PROTEIN INTERACTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; BIOLOGICAL ONTOLOGY; CHEMISTRY; CLASSIFICATION; METABOLISM; PROCEDURES;

BIOLOGICAL ONTOLOGIES; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; MEMBRANE TRANSPORT PROTEINS; PHARMACEUTICAL PREPARATIONS;

EID: 84901188446     PISSN: None     EISSN: 17406749     Source Type: Journal    
DOI: 10.1016/j.ddtec.2014.03.005     Document Type: Review

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