Group III/IV muscle afferents impair limb blood in patients with chronic heart failure

International Journal of Cardiology

Volumn 174, Issue 2, 2014, Pages 368-375

  Amann, Markus ^a,b   Venturelli, Massimo ^a   Ives, Stephen J ^b   Morgan, David E ^a   Gmelch, Benjamin ^a   Witman, Melissa A H ^b   Jonathan Groot, H ^b   Walter Wray, D ^a,b   Stehlik, Josef ^a   Richardson, Russell S ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

Autonomic control; Circulation; Exercise pressor reflex; Sensory neurons

Indexed keywords

FENTANYL;

ADULT; AFFERENT NERVE GROUP 4; AFFERENT NERVE GROUP III; AGED; ARTICLE; AUTONOMIC DYSFUNCTION; CARDIOVASCULAR RESPONSE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY HEMODYNAMICS; EXERCISE TEST; EXERCISE TOLERANCE; FATIGUE; FEMORAL ARTERY FLOW; HEART FAILURE; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HUMAN; MALE; MUSCLE SPINDLE AFFERENT NERVE; MUSCLE STRENGTH; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; BLOOD FLOW; CHRONIC DISEASE; EXERCISE; INNERVATION; LEG; MIDDLE AGED; MUSCLE FATIGUE; PATHOPHYSIOLOGY; PHYSIOLOGY; SENSORY NERVE CELL; SKELETAL MUSCLE; VASCULARIZATION;

AGED; CHRONIC DISEASE; EXERCISE; HEART FAILURE; HUMANS; LEG; MALE; MIDDLE AGED; MUSCLE FATIGUE; MUSCLE, SKELETAL; NEURONS, AFFERENT; REGIONAL BLOOD FLOW;

EID: 84901039798     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.04.157     Document Type: Article

References (40)

1. C.M. Adreani, J.M. Hill, and M.P. Kaufman Responses of group III and IV muscle afferents to dynamic exercise J Appl Physiol 82 1997 1811 1817
2. M.N. Murphy, M. Mizuno, J.H. Mitchell, and S.A. Smith Cardiovascular regulation by skeletal muscle reflexes in health and disease Am J Physiol Heart Circ Physiol 301 2011 H1191 H1204
3. T.G. Waldrop, F.L. Eldridge, G.A. Iwamoto, and J.H. Mitchell Central neural control of respiration and circulation during exercise L.B. Rowell, J.T. Shepherd, Handbook of physiology section 12: Exercise: regulation and integration of multiple systems 1996 Oxford University Press New York 333 380
4. M. Amann, S. Runnels, and D.E. Morgan et al. On the contribution of group III and IV muscle afferents to the circulatory response to rhythmic exercise in humans J Physiol 589 2011 3855 3866
5. M. Amann, G.M. Blain, L.T. Proctor, J.J. Sebranek, D.F. Pegelow, and J.A. Dempsey Group iii and iv muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans J Appl Physiol 109 2010 966 976
6. M. Amann, G.M. Blain, L.T. Proctor, J.J. Sebranek, D.F. Pegelow, and J.A. Dempsey Implications of group III and IV muscle afferents for high intensity endurance exercise performance in humans J Physiol 589 2011 5299 5309
7. M.F. Piepoli, K. Dimopoulos, A. Concu, and A. Crisafulli Cardiovascular and ventilatory control during exercise in chronic heart failure: role of muscle reflexes Int J Cardiol 130 2008 3 10
8. M.G. Garry Abnormalities of the exercise pressor reflex in heart failure Exerc Sport Sci Rev 39 2011 167 176
9. T.P. Olson, M.J. Joyner, and B.D. Johnson Influence of locomotor muscle metaboreceptor stimulation on the ventilatory response to exercise in heart failure Circ Heart Fail 3 2010 212 219
10. C.F. Notarius, D.J. Atchison, and J.S. Floras Impact of heart failure and exercise capacity on sympathetic response to handgrip exercise Am J Physiol Heart Circ Physiol 280 2001 H969 H976
11. M.F. Piepoli, and A.J. Coats Increased metaboreceptor stimulation explains the exaggerated exercise pressor reflex seen in heart failure J Appl Physiol 102 2007 494 496 [discussion 496-497]
12. H.R. Middlekauff, and L.I. Sinoway Increased mechanoreceptor stimulation explains the exaggerated exercise pressor reflex seen in heart failure J Appl Physiol 102 2007 492 494 [discussion 496]
13. P.M. Vanhoutte Adjustments in the peripheral circulation in chronic heart failure Eur Heart J 4 1983 67 83
14. M.J. Sullivan, J.D. Knight, M.B. Higginbotham, and F.R. Cobb Relation between central and peripheral hemodynamics during exercise in patients with chronic heart failure. Muscle blood flow is reduced with maintenance of arterial perfusion pressure Circulation 80 1989 769 781
15. R.L. Hammond, R.A. Augustyniak, N.F. Rossi, K. Lapanowski, J.C. Dunbar, and D.S. O'Leary Alteration of humoral and peripheral vascular responses during graded exercise in heart failure J Appl Physiol 90 2001 55 61
16. M. Klosinska, T. Rudzinski, P. Grzelak, L. Stefanczyk, J. Drozdz, and M. Krzeminska-Pakula Endothelium-dependent and -independent vasodilation is more attenuated in ischaemic than in non-ischaemic heart failure Eur J Heart Fail 11 2009 765 770
17. T.A. Rehn, M. Munkvik, P.K. Lunde, I. Sjaastad, and O.M. Sejersted Intrinsic skeletal muscle alterations in chronic heart failure patients: a disease-specific myopathy or a result of deconditioning? Heart Fail Rev 17 2012 421 436
18. K. Okita, S. Kinugawa, and H. Tsutsui Exercise intolerance in chronic heart failure-skeletal muscle dysfunction and potential therapies Circ J 77 2013 293 300
19. M. Amann, L.T. Proctor, J.J. Sebranek, D.F. Pegelow, and J.A. Dempsey Opioid-mediated muscle afferents inhibit central motor drive and limit peripheral muscle fatigue development in humans J Physiol 587 2009 271 283
20. W.J. Bos, B.P. Imholz, J. van Goudoever, K.H. Wesseling, and G.A. van Montfrans The reliability of noninvasive continuous finger blood pressure measurement in patients with both hypertension and vascular disease Am J Hypertens 5 1992 529 535
21. H. Nagasaka, and T.L. Yaksh Effects of intrathecal mu, delta, and kappa agonists on thermally evoked cardiovascular and nociceptive reflexes in halothane-anesthetized rats Anesth Analg 80 1995 437 443
22. D.M. Gaumann, T.L. Yaksh, and G.M. Tyce Effects of intrathecal morphine, clonidine, and midazolam on the somato-sympathoadrenal reflex response in halothane-anesthetized cats Anesthesiology 73 1990 425 432
23. J.M. Hill, and M.P. Kaufman Attenuation of reflex pressor and ventilatory responses to static muscular contraction by intrathecal opioids J Appl Physiol 68 1990 2466 2472
24. D.S. O'Leary, and R.A. Augustyniak Muscle metaboreflex increases ventricular performance in conscious dogs Am J Physiol 275 1998 H220 H224
25. R. Boushel Muscle metaboreflex control of the circulation during exercise Acta Physiol 199 2010 367 383
26. D.D. Sheriff, R.A. Augustyniak, and D.S. O'Leary Muscle chemoreflex-induced increases in right atrial pressure Am J Physiol 275 1998 H767 H775
27. D.S. O'Leary, J.A. Sala-Mercado, R.A. Augustyniak, R.L. Hammond, N.F. Rossi, and E.J. Ansorge Impaired muscle metaboreflex-induced increases in ventricular function in heart failure Am J Physiol Heart Circ Physiol 287 2004 H2612 H2618
28. I.H. Zucker, H.D. Schultz, Y.F. Li, Y. Wang, W. Wang, and K.P. Patel The origin of sympathetic outflow in heart failure: the roles of angiotensin II and nitric oxide Prog Biophys Mol Biol 84 2004 217 232
29. J.K. Kim, J.A. Sala-Mercado, R.L. Hammond, J. Rodriguez, T.J. Scislo, and D.S. O'Leary Attenuated arterial baroreflex buffering of muscle metaboreflex in heart failure Am J Physiol Heart Circ Physiol 289 2005 H2416 H2423
30. K. Narkiewicz, C.A. Pesek, P.J. van de Borne, M. Kato, and V.K. Somers Enhanced sympathetic and ventilatory responses to central chemoreflex activation in heart failure Circulation 100 1999 262 267
31. A. Di Vanna, A.M. Braga, and M.C. Laterza et al. Blunted muscle vasodilatation during chemoreceptor stimulation in patients with heart failure Am J Physiol Heart Circ Physiol 293 2007 H846 H852
32. C. Indolfi, A. Maione, and M. Volpe et al. Forearm vascular responsiveness to alpha 1- and alpha 2-adrenoceptor stimulation in patients with congestive heart failure Circulation 90 1994 17 22
33. R.L. Hammond, R.A. Augustyniak, N.F. Rossi, P.C. Churchill, K. Lapanowski, and D.S. O'Leary Heart failure alters the strength and mechanisms of the muscle metaboreflex Am J Physiol Heart Circ Physiol 278 2000 H818 H828
34. M. Amann, and J.A. Calbet Convective oxygen transport and fatigue J Appl Physiol 104 2008 861 870
35. M. Amann, and J.A. Dempsey Locomotor muscle fatigue modifies central motor drive in healthy humans and imposes a limitation to exercise performance J Physiol 586 2008 161 173
36. D.C. Poole, D.M. Hirai, S.W. Copp, and T.I. Musch Muscle oxygen transport and utilization in heart failure: implications for exercise (in)tolerance Am J Physiol Heart Circ Physiol 302 2012 H1050 H1063
37. J.R. Wilson, J.L. Martin, and N. Ferraro Impaired skeletal muscle nutritive flow during exercise in patients with congestive heart failure: role of cardiac pump dysfunction as determined by the effect of dobutamine Am J Cardiol 53 1984 1308 1315
38. C.S. Maskin, R. Forman, E.H. Sonnenblick, W.H. Frishman, and T.H. LeJemtel Failure of dobutamine to increase exercise capacity despite hemodynamic improvement in severe chronic heart failure Am J Cardiol 51 1983 177 182
39. H.J. Wang, Y.L. Li, L. Gao, I.H. Zucker, and W. Wang Alteration in skeletal muscle afferents in rats with chronic heart failure J Physiol 588 2010 5033 5047
40. S.A. Smith, J.H. Mitchell, R.H. Naseem, and M.G. Garry Mechanoreflex mediates the exaggerated exercise pressor reflex in heart failure Circulation 112 2005 2293 2300