메뉴 건너뛰기




Volumn 24, Issue 5, 2014, Pages 605-613

Naringenin exerts cytoprotective effect against paraquat-induced toxicity in human bronchial epithelial BEAS-2B cells through NRF2 activation

Author keywords

Antioxidant related genes; Human bronchial epithelial BEAS 2B cells; Naringenin; Paraquat

Indexed keywords

GLUTATHIONE PEROXIDASE 2; GLUTATHIONE PEROXIDASE 3; HEME OXYGENASE 1; NARINGENIN; PARAQUAT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; FLAVANONE DERIVATIVE; HERBICIDE;

EID: 84901014569     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1402.02001     Document Type: Article
Times cited : (44)

References (26)
  • 1
    • 0021288059 scopus 로고
    • Paraquat: Model for oxidantinitiated toxicity
    • Bus JS, Gibson JE. 1984. Paraquat: model for oxidantinitiated toxicity. Environ. Health Perspect. 55: 37-46.
    • (1984) Environ. Health Perspect , vol.55 , pp. 37-46
    • Bus, J.S.1    Gibson, J.E.2
  • 2
    • 0027194207 scopus 로고
    • Cytokines and pulmonary fibroses
    • Carre P, Leophonte P. 1993. [Cytokines and pulmonary fibroses]. Rev. Mal. Respir. 10: 193-207.
    • (1993) Rev. Mal. Respir , vol.10 , pp. 193-207
    • Carre, P.1    Leophonte, P.2
  • 3
    • 68849087516 scopus 로고    scopus 로고
    • Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice
    • Chabory E, Damon C, Lenoir A, Kauselmann G, Kern H, Zevnik B, et al. 2009. Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice. J. Clin. Invest. 119: 2074-2085.
    • (2009) J. Clin. Invest , vol.119 , pp. 2074-2085
    • Chabory, E.1    Damon, C.2    Lenoir, A.3    Kauselmann, G.4    Kern, H.5    Zevnik, B.6
  • 4
    • 0035836698 scopus 로고    scopus 로고
    • An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
    • Chan K, Han XD, Kan YW. 2001. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc. Natl. Acad. Sci. USA 98: 4611-4616.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4611-4616
    • Chan, K.1    Han, X.D.2    Kan, Y.W.3
  • 5
    • 84870679159 scopus 로고    scopus 로고
    • Effect of betacyclodextrin complexation on solubility and enzymatic conversion of naringin
    • Cui L, Zhang ZH, Sun E, Jia XB. 2012. Effect of betacyclodextrin complexation on solubility and enzymatic conversion of naringin. Int. J. Mol. Sci. 13: 14251-14261.
    • (2012) Int. J. Mol. Sci , vol.13 , pp. 14251-14261
    • Cui, L.1    Zhang, Z.H.2    Sun, E.3    Jia, X.B.4
  • 6
    • 84867775103 scopus 로고    scopus 로고
    • Naringin modulates oxidative stress and inflammation in 3-nitropropionic acidinduced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway
    • Gopinath K, Sudhandiran G. 2012. Naringin modulates oxidative stress and inflammation in 3-nitropropionic acidinduced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway. Neuroscience 227: 134-143.
    • (2012) Neuroscience , vol.227 , pp. 134-143
    • Gopinath, K.1    Sudhandiran, G.2
  • 7
    • 84880634169 scopus 로고    scopus 로고
    • Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development
    • Hao Q, Lu X, Liu N, Xue X, Li M, Zhang C, et al. 2013. Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development. BMB Rep. 46: 316-321.
    • (2013) BMB Rep , vol.46 , pp. 316-321
    • Hao, Q.1    Lu, X.2    Liu, N.3    Xue, X.4    Li, M.5    Zhang, C.6
  • 9
    • 67349247003 scopus 로고    scopus 로고
    • Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents
    • Higgins LG, Kelleher MO, Eggleston IM, Itoh K, Yamamoto M, Hayes JD. 2009. Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents. Toxicol. Appl. Pharmacol. 237: 267-280.
    • (2009) Toxicol. Appl. Pharmacol , vol.237 , pp. 267-280
    • Higgins, L.G.1    Kelleher, M.O.2    Eggleston, I.M.3    Itoh, K.4    Yamamoto, M.5    Hayes, J.D.6
  • 10
    • 84886249424 scopus 로고    scopus 로고
    • The reversal of paraquat-induced mitochondria-mediated apoptosis by cycloartenyl ferulate, the important role of Nrf2 pathway
    • Hong GL, Liu JM, Zhao GJ, Wang L, Liang G, Wu B, et al. 2013. The reversal of paraquat-induced mitochondria-mediated apoptosis by cycloartenyl ferulate, the important role of Nrf2 pathway. Exp. Cell Res. 319: 2845-2855.
    • (2013) Exp. Cell Res , vol.319 , pp. 2845-2855
    • Hong, G.L.1    Liu, J.M.2    Zhao, G.J.3    Wang, L.4    Liang, G.5    Wu, B.6
  • 11
    • 33644649421 scopus 로고    scopus 로고
    • Nrf2: A potential molecular target for cancer chemoprevention by natural compounds
    • Jeong WS, Jun M, Kong AN. 2006. Nrf2: a potential molecular target for cancer chemoprevention by natural compounds. Antioxid. Redox Signal. 8: 99-106.
    • (2006) Antioxid. Redox Signal , vol.8 , pp. 99-106
    • Jeong, W.S.1    Jun, M.2    Kong, A.N.3
  • 12
    • 78149434112 scopus 로고    scopus 로고
    • The Nrf2 system as a potential target for the development of indirect antioxidants
    • Jung KA, Kwak MK. 2010. The Nrf2 system as a potential target for the development of indirect antioxidants. Molecules 15: 7266-7291.
    • (2010) Molecules , vol.15 , pp. 7266-7291
    • Jung, K.A.1    Kwak, M.K.2
  • 14
    • 84876907783 scopus 로고    scopus 로고
    • Antioxidant action of ellagic acid ameliorates paraquat-induced A549 cytotoxicity
    • Kim YS, Zerin T, Song HY. 2013. Antioxidant action of ellagic acid ameliorates paraquat-induced A549 cytotoxicity. Biol. Pharm. Bull. 36: 609-615.
    • (2013) Biol. Pharm. Bull , vol.36 , pp. 609-615
    • Kim, Y.S.1    Zerin, T.2    Song, H.Y.3
  • 15
    • 84871212366 scopus 로고    scopus 로고
    • Neuroprotective effects of tert-butylhydroquinone on paraquatinduced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells
    • Li H, Wu S, Wang Z, Lin W, Zhang C, Huang B. 2012. Neuroprotective effects of tert-butylhydroquinone on paraquatinduced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells. Arch. Toxicol. 86: 1729-1740.
    • (2012) Arch. Toxicol , vol.86 , pp. 1729-1740
    • Li, H.1    Wu, S.2    Wang, Z.3    Lin, W.4    Zhang, C.5    Huang, B.6
  • 16
    • 33744729373 scopus 로고    scopus 로고
    • Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2
    • Ma Q, Battelli L, Hubbs AF. 2006. Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2. Am. J. Pathol. 168: 1960-1974.
    • (2006) Am. J. Pathol , vol.168 , pp. 1960-1974
    • Ma, Q.1    Battelli, L.2    Hubbs, A.F.3
  • 17
    • 84867041441 scopus 로고    scopus 로고
    • Molecular basis of electrophilic and oxidative defense: Promises and perils of Nrf2
    • Ma Q, He X. 2012. Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2. Pharmacol. Rev. 64: 1055-1081.
    • (2012) Pharmacol. Rev , vol.64 , pp. 1055-1081
    • Ma, Q.1    He, X.2
  • 18
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta PG. 2000. Flavonoids as antioxidants. J. Nat. Prod. 63: 1035-1042.
    • (2000) J. Nat. Prod , vol.63 , pp. 1035-1042
    • Pietta, P.G.1
  • 19
    • 84864134568 scopus 로고    scopus 로고
    • Antioxidant effect of silymarin on paraquat-induced human lung adenocarcinoma A549 cell line
    • Podder B, Kim YS, Zerin T, Song HY. 2012. Antioxidant effect of silymarin on paraquat-induced human lung adenocarcinoma A549 cell line. Food Chem. Toxicol. 50: 3206-3214.
    • (2012) Food Chem. Toxicol , vol.50 , pp. 3206-3214
    • Podder, B.1    Kim, Y.S.2    Zerin, T.3    Song, H.Y.4
  • 20
    • 58149233844 scopus 로고    scopus 로고
    • Naringenin protects against cadmium-induced oxidative renal dysfunction in rats
    • Renugadevi J, Prabu SM. 2009. Naringenin protects against cadmium-induced oxidative renal dysfunction in rats. Toxicology 256: 128-134.
    • (2009) Toxicology , vol.256 , pp. 128-134
    • Renugadevi, J.1    Prabu, S.M.2
  • 21
    • 0029888128 scopus 로고    scopus 로고
    • Structureantioxidant activity relationships of flavonoids and phenolic acids
    • Rice-Evans CA, Miller NJ, Paganga G. 1996. Structureantioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 20: 933-956.
    • (1996) Free Radic. Biol. Med , vol.20 , pp. 933-956
    • Rice-Evans, C.A.1    Miller, N.J.2    Paganga, G.3
  • 22
    • 79251602108 scopus 로고    scopus 로고
    • Naringenin, a flavanone, inhibits the proliferation of cerebrally implanted C6 glioma cells in rats
    • Sabarinathan D, Mahalakshmi P, Vanisree AJ. 2011. Naringenin, a flavanone, inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. Chem. Biol. Interact. 189: 26-36.
    • (2011) Chem. Biol. Interact , vol.189 , pp. 26-36
    • Sabarinathan, D.1    Mahalakshmi, P.2    Vanisree, A.J.3
  • 23
    • 56249106571 scopus 로고    scopus 로고
    • Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
    • Surh YJ, Kundu JK, Na HK. 2008. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Med. 74: 1526-1539.
    • (2008) Planta Med , vol.74 , pp. 1526-1539
    • Surh, Y.J.1    Kundu, J.K.2    Na, H.K.3
  • 24
    • 84973837740 scopus 로고
    • Paraquat poisoning: Clinical features and immediate general management
    • Vale JA, Meredith TJ, Buckley BM. 1987. Paraquat poisoning: clinical features and immediate general management. Hum. Toxicol. 6: 41-47.
    • (1987) Hum. Toxicol , vol.6 , pp. 41-47
    • Vale, J.A.1    Meredith, T.J.2    Buckley, B.M.3
  • 26
    • 84886101441 scopus 로고    scopus 로고
    • Quercetin reduces oxidative damage induced by paraquat via modulating expression of antioxidant genes in A549 cells
    • Zerin T, Kim YS, Hong SY, Song HY. 2013. Quercetin reduces oxidative damage induced by paraquat via modulating expression of antioxidant genes in A549 cells. J. Appl. Toxicol. 33: 1460-1467.
    • (2013) J. Appl. Toxicol , vol.33 , pp. 1460-1467
    • Zerin, T.1    Kim, Y.S.2    Hong, S.Y.3    Song, H.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.