Isolation of a new broad spectrum antifungal polyene from Streptomyces sp. MTCC 5680

Letters in Applied Microbiology

Volumn 58, Issue 6, 2014, Pages 591-596

  Vartak, A ^a   Mutalik, V ^a   Parab, R R ^a   Shanbhag, P ^a   Bhave, S ^a   Mishra, P D ^a   Mahajan, G B ^a  

^a Piramal Enterprises Limited   (India)

Author keywords

Actinomycetes; Antibiotics; Antimicrobials; Pharmaceuticals; Streptomycetes

Indexed keywords

ASPERGILLUS; BACTERIA; CANDIDA; ORGANIC COMPOUNDS;

ACTINOMYCETE; ANTIFUNGALS; ANTIMICROBIAL; BROAD SPECTRUM; FERMENTATION BROTHS; MACROLIDE ANTIBIOTICS; POLYENE MACROLIDE; STREPTOMYCES SP; STREPTOMYCETES; WILD-TYPE STRAIN;

ANTIBIOTICS;

AMPHOTERICIN B; ANTIFUNGAL AGENT; FLUCONAZOLE; GENTAMICIN; MACROLIDE; PN 00053; ROFLAMYCOIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; BIOACTIVITY; CHROMATOGRAPHY; FERMENTATION; GROWTH RATE; MOUNTAIN REGION; PHYSICOCHEMICAL PROPERTY; YEAST;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CARBON NUCLEAR MAGNETIC RESONANCE; CRYPTOCOCCUS NEOFORMANS; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; FILAMENTOUS FUNGUS; FUNGICIDAL ACTIVITY; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; IN VITRO STUDY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STREPTOMYCES; STREPTOMYCES MTCC 5680; SUBMERGED FERMENTATION; TRICHOPHYTON;

HIMACHAL PRADESH; INDIA;

ACTINOBACTERIA (CLASS); ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; FILOBASIDIELLA NEOFORMANS; FUNGI; NEGIBACTERIA; POSIBACTERIA; STREPTOMYCES SP.; STREPTOMYCINEAE; TRICHOPHYTON;

ACTINOMYCETES; ANTIBIOTICS; ANTIMICROBIALS; PHARMACEUTICALS; STREPTOMYCETES;

ANTIBIOSIS; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; DRUG EVALUATION, PRECLINICAL; FLUCONAZOLE; MACROLIDES; MICROBIAL SENSITIVITY TESTS; POLYENES; SOIL MICROBIOLOGY; STREPTOMYCES; TRICHOPHYTON;

EID: 84901007442     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/lam.12229     Document Type: Article

References (17)

1. Ana, K.R.A., Kioshima, E.S., Teixeira, M.M., Martins, N.F., Maigret, B. and Felipe, M.S. (2011) Comparative genomics allowed the identification of drug targets against human fungal pathogens. BMC Genomics 12, 75.
2. Andriole, V.T. (1999) Current and future therapy of invasive fungal infections. In 18 Current Clinical Topics in Infectious Diseases, eds Remington, J. and Swartz, M. pp. 19-36. Malden, MA: Blackwell Sciences.
3. Arun, D.S. and Jaspreet, S. (2005) A nonenzymatic method to isolate genomic DNA from bacteria and actinomycete. Anal Biochem 337, 354-356.
4. Eva Stodůlková, E., Kuzma, M., Hench, I.B., Černý, J., Králová, J., Novák, P., Chudíčková, M., Savic, M. et al. (2011) New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis. J Antibiot 64, 717-722.
5. Groll, A.H., Shah, P.M., Mentzel, C., Schneider, M., Just-Nuebling, G. and Huebner, K. (1996) Trends in the postmortem epidemiology of invasive fungal infections at a university hospital. J Infect 33, 23-32.
6. Groll, A.H., Piscitelli, S.C. and Walsh, T.J. (1998) Clinical pharmacology of systemic antifungal agents: a comprehensive review of agents in clinical use, current investigational compounds, and putative targets for antifungal drug development. Adv Pharmacol 44, 343-500.
7. Locci, R. (1989) Streptomyces and related genera. In Bergey's Manual of Systematic Bacteriology eds Williams, S.T. and Holt, J.G. pp. 2451-2469. Baltimore, USA: Williams and Wilkins Company.
8. Mahajan, G.M. and Balachandran, L. (2012) Antibacterial agents from Actinomycetes - A Review. Front Biosci E4, 240-253.
9. Morgan, J. (2005) Global trends in candidemia: review of reports from 1995-2005. Curr Infect Dis Rep 7, 429-439.
10. Nathan, P., Law, E.J., Murphy, D.F. and Mac Millan, B.G. (1978) Laboratory methods for selection of topical antimicrobial agents to treat infected burn wounds. Burns 4, 177-187.
11. NCCLS (National Committee for Clinical Laboratory Standards) (2002a) Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; NCCLS Document M27-A2 [ISBN 1-56238-469-4], Wayne: Clinical and Laboratory Standards Institute. Approved Standard - Second Edition.
12. NCCLS (National Committee for Clinical Laboratory Standards) (2002b. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi; NCCLS Document M38-A [ISBN 1-56238-470-8]. Wayne: Clinical and Laboratory Standards Institute. Approved Standard - Second Edition.
13. Ostrosky-Zeichner, L., Casadevall, A., Galgiani, J.N., Odds, F.C. and Rex, J.H. (2010) An insight into the antifungal pipeline: selected new molecules and beyond. Nat Rev Drug Discov 9, 719-727.
14. Schlegel, R., Thrum, H., Zielinski, J. and Borowski, E. (1971) A new polyene antibiotic, Flavomycoin: structural investigations. J. Antibiot 34, 122-123.
15. Schlegel, R. and Thrum, H. (1981) A new polyene antibiotic, flavomycoin. Structural investigations. I. J Antibiot 24, 360-374.
16. Shirling, E.B. and Gottlie, D. (1966) Methods for characterization of Streptomyces species. Int J Syst Bacteriol 16, 313-340.
17. Wellington, E.M.H. and Cross, T. (1983) Taxonomy of antibiotic producing Actinomycetes and new approaches to their selective isolation. In Progress in Industrial Microbiology ed. Bushell, M.E. pp. 36. Amsterdam: Elsevier.