Enriched environment upregulates growthassociated protein 43 expression in the hippocampus and enhances cognitive abilities in prenatally stressed rat offspring

Neural Regeneration Research

Volumn 7, Issue 25, 2012, Pages 1967-1973

  Zhang, Zhengyu ^a   Zhang, Hua ^b   Du, Baoling ^a   Chen, Zhiqiang ^c  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

^c LIAOCHENG PEOPLE'S HOSPITAL   (China)

Author keywords

Cognition; Enriched environment; Growth associated protein 43; Hippocampus; Morris water maze; Neural regeneration; Prenatal restraint stress

Indexed keywords

EID: 84901002912     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2012.25.007     Document Type: Article

References (22)

1. [1] Weinstock M. Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Prog Neurobiol. 2001;65(5):427-451.
2. [2] Zagron G, Weinstock M. Maternal adrenal hormone secretion mediates behavioural alterations induced by prenatal stress in male and female rats. Behav Brain Res. 2006;175(2):323-328.
3. [3] Afadlal S, Polaboon N, Surakul P, et al. Prenatal stress alters presynaptic marker proteins in the hippocampus of rat pups. Neurosci Lett. 2010;470(1):24-27.
4. [4] Reagan LP, McEwen BS. Controversies surrounding glucocorticoid-mediated cell death in the hippocampus. J Chem Neuroanat. 1997;13(3):149-167.
5. [5] Benowitz LI, Routtenberg A. GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci. 1997;20(2):84-91.
6. [6] Kaneda M, Nagashima M, Nunome T, et al. Changes of phospho-growth-associated protein 43 (phospho-GAP43) in the zebrafish retina after optic nerve injury: a long-term observation. Neurosci Res. 2008;61(3):281-288.
7. [7] Jutapakdeegul N, Afadlal S, Polaboon N, et al. Repeated restraint stress and corticosterone injections during late pregnancy alter GAP-43 expression in the hippocampus and prefrontal cortex of rat pups. Int J Dev Neurosci. 2010; 28(1):83-90.
8. [8] Sun H, Zhang J, Zhang L, et al. Environmental enrichment influences BDNF and NR1 levels in the hippocampus and restores cognitive impairment in chronic cerebral hypoperfused rats. Curr Neurovasc Res. 2010;7(4): 268-280.
9. [9] Kozorovitskiy Y, Gross CG, Kopil C, et al. Experience induces structural and biochemical changes in the adult primate brain. Proc Natl Acad Sci U S A. 2005;102(48): 17478-17482.
10. [10] Gomez-Pinilla F, Ying Z, Agoncillo T, et al. The influence of naturalistic experience on plasticity markers in somatosensory cortex and hippocampus: effects of whisker use. Brain Res. 2011;1388:39-47.
11. [11] Neeley EW, Berger R, Koenig JI, et al. Strain dependent effects of prenatal stress on gene expression in the rat hippocampus. Physiol Behav. 2011;104(2):334-339.
12. [12] Markham JA, Taylor AR, Taylor SB, et al. Characterization of the cognitive impairments induced by prenatal exposure to stress in the rat. Front Behav Neurosci. 2010;4:173.
13. [13] Dupouy JP, Coffigny H, Magre S. Maternal and foetal corticosterone levels during late pregnancy in rats. J Endocrinol. 1975;65(3):347-352.
14. [14] Casoli T, Di Stefano G, Gracciotti N, et al. Cellular distribution of GAP-43 mRNA in hippocampus and cerebellum of adult rat brain by in situ RT-PCR. J Histochem Cytochem. 2001;49(9):1195-1196.
15. [15] Chao HM, McEwen BS. Glucocorticoids and the expression of mRNAs for neurotrophins, their receptors and GAP-43 in the rat hippocampus. Brain Res Mol Brain Res. 1994;26(1-2):271-276.
16. [16] Gauthier-Campbell C, Bredt DS, Murphy TH, et al. Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs. Mol Biol Cell. 2004;15(5):2205-2217.
17. [17] Liu HX, Zhang JJ, Zheng P, et al. Altered expression of MAP-2, GAP-43, and synaptophysin in the hippocampus of rats with chronic cerebral hypoperfusion correlates with cognitive impairment. Brain Res Mol Brain Res. 2005; 139(1):169-177.
18. [18] Tagaya M, Matsuyama T, Nakamura H, et al. Increased F1/GAP-43 mRNA accumulation in gerbil hippocampus after brain ischemia. J Cereb Blood Flow Metab. 1995; 15(6):1132-1136.
19. [19] Zohar I, Weinstock M. Differential effect of prenatal stress on the expression of corticotrophin-releasing hormone and its receptors in the hypothalamus and amygdala in male and female rats. J Neuroendocrinol. 2011;23(4): 320-328.
20. [20] Wilson R, Barnes L, Bennett D. Assessment of lifetime participation in cognitively stimulating activities. J Clin Exp Neuropsychol. 2003;25(5):634-642.
21. [21] Rampon C, Jiang CH, Dong H, et al. Effects of environmental enrichment on gene expression in the brain. Proc Natl Acad Sci U S A. 2000;97(23):12880-12884.
22. [22] Kage M, Ikemoto A, Akiguchi I, et al. Primary structure of GAP-43 mRNA expressed in the spinal cord of ALS patients. Neuroreport. 1998;9(7):1403-1406.