Cytotoxicity of cinnamon-flavored electronic cigarette refills: Are the results truly applicable to electronic cigarette use?

Toxicology in Vitro

Volumn 28, Issue 5, 2014, Pages 1016-1017

  Farsalinos, K E ^a   Romagna, G ^b   Voudris, V ^a  

^a ONASSIS CARDIAC SURGERY CENTER   (Greece)

^b Verbania Fondotoce   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CINNAMALDEHYDE; ELECTRONIC CIGARETTE; FLAVORING AGENT;

CHEMICAL ANALYSIS; CINNAMON; CLINICAL EFFECTIVENESS; CONCENTRATION (PARAMETERS); CYTOTOXICITY; FOOD AND DRUG ADMINISTRATION; HUMAN; LETTER; NONHUMAN; OUTCOME ASSESSMENT; SAFETY; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; VAPOR; CINNAMOMUM ZEYLANICUM; TOBACCO; TOXICITY;

CINNAMOMUM ZEYLANICUM; FLAVORING AGENTS; HUMANS; TOBACCO PRODUCTS;

EID: 84901000591     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.04.016     Document Type: Letter

References (6)

1. Behar R.Z., Davis B., Wang Y., Bahl V., Lin S., Talbot P. Identification of toxicants in cinnamon-flavored electronic cigarette refill fluids. Toxicol. in Vitro 2013, doi:http://dx.doi.org/10.1016/j.tiv.2013.10.006.
2. EPA, 2010. Cinnamaldehyde (040506) fact sheet. (accessed 01.11.13). http://www.epa.gov/pesticides/chem_search/reg_actions/registration/fs_PC-040506_1-Oct-98.pdf.
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4. Flick, E.W., 1998. Industrial Solvents Handbook, 5th ed., ISBN 0-8155-1413-1.
5. National Toxicology Program, 2004. NTP technical report on the toxicology and carcinogenesis studies of trans-cinnamaldehyde (microencapsulated) (CAS NO. 14371-10-9) in F344/N rats and B6C3F1 mice. National Institute of Health. (accessed 01.11.13). http://www.ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr514.pdf.
6. Romagna G., Allifranchini E., Bocchietto E., Todeschi S., Esposito M., Farsalinos K.E. Cytotoxicity evaluation of electronic cigarette vapor extract on cultured mammalian fibroblasts (ClearStream-LIFE): comparison with tobacco cigarette smoke extract. Inhal. Toxicol. 2013, 25:354-361.