The mitochondrial F1Fo ATP synthase

Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes

Volumn , Issue , 2007, Pages 119-134

  Gaballo, A ^a   Papa, S ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84900906784     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-30411-3_6     Document Type: Chapter

References (142)

1. Abrahams JP, Leslie AGW, Lutter R, Walker JE. 1994. Structure at 2.8 Å resolution of F1-ATPase from bovine heart mitochondria. Nature 370:621-628.
2. Abrahams JP, Buchanan SK, Van Raaij MJ, Fearnley IM, Leslie AG, et al. 1996. The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin. Proc Natl Acad Sci USA 93:9420-9424.
3. Ackerman SH, Tzagoloff A. 1990a. ATP 10, a yeast nuclear gene required for the assembly of the mitochondrial F1-F0 complex. J Biol Chem 265:9952-9959.
4. Ackerman SH, Tzagoloff A. 1990b. Identification of two nuclear genes (ATP11, ATP12) required for assembly of the yeast F1-ATPase. Proc Natl Acad Sci USA 87:4986-4990.
5. Aggeler R, Ogilvie I, Capaldi RA. 1997. Rotation of a gamma-epsilon subunit domain in the Escherichia coli F1F0-AT P synthase complex. The gamma-epsilon subunits are essentially randomly distributed relative to the alpha3beta3delta domain in the intact complex. J Biol Chem 272:19621-19624.
6. +-ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells. Mol Cancer Res 1:931-939.
7. Arakaki N, Ueyama Y, Hirose M, Himeda T, Shibata H, et al. 2001. Stoichiometry of subunit e in rat liver mitochondrial H (+)-ATP synthase and membrane topology of its putative Ca (2+)-dependent regulatory region. Biochim Biophys Acta 1504:220-228.
8. Arnold I, Pfeiffer K, Neupert W, Stuart RA, Schagger H. 1998. Yeast mitochondrial F1F0-ATP synthase exists as a dimer: Identification of three dimer-specific subunits. EMBO J 17:7170-7178.
9. Beal MF. 1992. Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann Neurol 31:119-130.
10. Beal MF. 1995. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 38:357-366.
11. Belogrudov GI, Tomich JM, Hatefi Y. 1996. Membrane topography and near-neighbor relationships of the mitochondrial ATPsynthase subunits e, f, and g. J Biol Chem 271:20340-20345.
12. Bianchet MA, Hullihen J, Pedersen PL, Amzel LM. 1998. The 2.8-Å structure of rat liver F1-ATPase: Configuration of a critical intermediate in ATP synthesis/hydrolysis. Proc Natl Acad Sci 95:11065-11070.
13. Birkenhager R, Hoppert M, Deckers-Hebestreit G, Mayer F, Altendorf K. 1995. The F0 complex of the Escherichia coli ATP synthase. Investigation by electron spectroscopic imaging and immunoelectron microscopy. Eur J Biochem 230:58-67.
14. Bottcher B, Schwarz L, Graber P. 1998. Direct indication for the existence of a double stalk in CF0F1. J Mol Biol 281:757-762.
15. Boyer PD. 1993. The binding change mechanism for ATP synthase-some probabilities and possibilities. Biochim Biophys Acta 1140:215-250.
16. Boyer PD. 1997. The ATP synthase-A splendid molecular machine. Annu Rev Biochem 66:717-749.
17. Boyer PD. 2000. Catalytic site forms and controls in ATP synthase catalysis. Biochim Biophys Acta 1458:252-262.
18. Boyer PD. 2002. Catalytic site occupancy during ATP synthase catalysis. FEBS Lett 512:29-32.
19. Braig K, Menz RI, Montgomery MG, Leslie AG, Walker JE. 2000. Structure of bovine mitochondrial F (1)-ATPase inhibited by Mg (2+) ADP and aluminium fluoride. Structure. 8:567-573.
20. Bravo C, Minauro-Sanmiguel F, Morales-Rios E, Rodriguez-Zavala JS, Garcia, JJ. 2004. Overexpression of the inhibitor protein IF (1) in AS-30D hepatoma produces a higher association with mitochondrial F (1) F (0) ATP synthase compared to normal rat liver: Functional and cross-linking studies. J Bioenerg Biomembr 36:257-264.
21. Burwick NR, Wahl ML, Fang J, Zhong Z, Moser TL, et al. 2004. An inhibitor of the F1 subunit of ATP synthase (IF1) modulates the activity of angiostatin on the endothelial cell surface. J Biol Chem 280:1740-1745.
22. Cabezon E, Montgomery MG, Leslie AG, Walker JE. 2003. The structure of bovine F1-ATPase in complex with its regulatory protein IF1. Nat Struct Biol 10:744-750.
23. Cabezon E, Runswick MJ, Leslie AG, Walker JE. 2001. The structure of bovine IF (1), the regulatory subunit of mitochondrial F-ATPase. EMBO J 20:6990-6996.
24. Cain BD. 2000. Mutagenic analysis of the F0 stator subunits. J Bioenerg Biomembr 32:365-371.
25. Capaldi RA, Aggeler R, Turina P, Wilkens S. 1994. Coupling between catalytic sites and the proton channel in F1F0-type ATPases. Trends Biochem Sci 19:284-289.
26. Capuano F, Guerrieri F, Papa S. 1997. Oxidative phosphorylation enzymes in normal and neoplastic cell growth. J Bioenerg Biomembr 29:379-384.
27. Chen C, Ko Y, Delannoy M, Ludtke SJ, Chiu W, et al. 2004. Mitochondrial ATP synthasome: Three-dimensional structure byelectron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. J Biol Chem 279:31761-31768.
28. Chernyak BV, Dedov VN, Gabai VL. 1994. Mitochondrial ATP hydrolysis and ATP depletion in thymocytes and Ehrlich ascites carcinoma cells. FEBS Lett 337:56-59.
29. Collinson IR, Fearnley IM, Skehel JM, Runswick MJ, Walker JE. 1994. ATP synthase from bovine heart mitochondria: Identification by proteolysis of sites in F0 exposed by removal of F1 and the oligomycin-sensitivity conferral protein. Biochem J 303:639-645.
30. Collinson IR, Skehel JM, Fearnley IM, Runswick MJ, Walker JE. 1996. The F1F0-ATPase complex from bovine heart mitochondria: The molar ratio of the subunits in the stalk region linking the F1 and F0 domains. Biochemistry 35:12640-12646.
31. Cox GB, Fimmel AL, Gibson F, Hatch L. 1986. The mechanism of ATP synthase: A reassessment of the functions of the b and a subunits. Biochim Biophys Acta 849:62-69.
32. Cox GB, Jans DA, Fimmel AL, Gibson F, Hatch L. 1984. Hypothesis. The mechanism of ATP synthase. Conformational change by rotation of the beta-subunit. Biochim Biophys Acta 768:201-208.
33. Das AM. 2003. Regulation of the mitochondrial ATP-synthase in health and disease. Mol Genet Metab 79:71-82.
34. Das AM, Jolly RD, Kohlschutter A. 1999. Anomalies of mitochondrial ATP synthase regulation in four different types of neuronal ceroid lipofuscinosis. Mol Genet Metab 66:349-355.
35. Das AM, Kohlschutter A. 1996. Decreased activity of the mitochondrial ATP-synthase in fibroblasts from children with late-infantile and juvenile neuronal ceroid lipofuscinosis. J Inherit Metab Dis 19:130-132.
36. De Meirleir L, Seneca S, Lissens W, De Clercq I, Eyskens F, et al. 2004. Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12. J Med Genet 41:120-124.
37. Diez M, Zimmermann B, Borsch M, Konig M, Schweinberger E, et al. 2004. Proton-powered subunit rotation in single membrane-bound F0F1-ATP synthase. Nat Struct Mol Biol 11:135-141.
38. Dmitriev OY, Altendorf K, Fillingame RH. 2004. Subunit A of the E.coli ATP synthase: Reconstitution and high resolution NMR with protein purified in a mixed polarity solvent. FEBS Lett 556:35-38.
39. Dmitriev OY, Jones PC, Fillingame RH. 1999. Structure of the subunit c oligomer in the F1F0 ATP synthase: Model derived from solution structure of the monomer and cross-linking in the native enzyme. Proc Natl Acad Sci USA 96:7785-7790.
40. Duncan TM, Bulygin VV, Zhou Y, Hutcheon ML, Cross RL. 1995. Rotation of subunits during catalysis by Escherichia coli F1-ATPase. Proc Natl Acad Sci USA 92:10964-10968.
41. Duvezin-Caubet S, Caron M, Giraud MF, Velours J, di Rago JP. 2003. The two rotor components of yeast mitochondrial ATP synthase are mechanically coupled by subunit delta. Proc Natl Acad Sci USA 100:13235-13240.
42. Everard-Gigot V, Dunn CD, Dolan BM, Brunner S, Jensen RE, et al. 2005. Functional Analysis of Subunit e of the F1F0-ATP Synthase of the Yeast Saccharomyces cerevisiae: Importance of the N-terminal membrane anchor region. Eukaryot Cell 4:346-355.
43. Fernandez-Moran H. 1962. Cell-membrane ultrastructure. Low-temperature electron microsopy and x-ray diffraction studies of lipoprotein components in lamellar systems. Circulation 26:1039-1065.
44. + transport and ATP synthesis in F1F0-ATP synthases: Glimpses of interacting parts in a dynamic molecular machine. J Exp Biol 200:217-224.
45. Fillingame RH, Angevine CM, Dmitriev OY. 2002a. Coupling proton movements to c-ring rotation in F (1) F (0) ATP synthase: Aqueous access channels and helix rotations at the a-c interface. Biochim Biophys Acta 1555:29-36.
46. Fillingame RH, Angevine CM, Dmitriev OY. 2003. Mechanics of coupling proton movements to c-ring rotation in ATP synthase. FEBS Lett 555:29-34.
47. +-transporting ATP synthase derived by solution NMR and intersubunit crosslinking in situ. Biochim Biophys Acta 1565:232-245.
48. Fillingame RH, Jiang W, Dmitriev OY. 2000. The oligomeric subunit C rotor in the Fo sector of ATP synthase: Unresolved questions in our understanding of function. J Bioenerg Biomembr 32:433-439.
49. Flott-Rahmel B, Falter C, Schluff P, Fingerhut R, Christensen E, et al. 1997. Nerve cell lesions caused by 3-hydroxyglutaric acid: A possible mechanism for neurodegeneration in glutaric acidaemia I. J Inherit Metab Dis 20:387-390.
50. +-ATP synthase. Biochemistry 37:17519-17526.
51. Gavin PD, Prescott M, Luff SE, Devenish RJ. 2004. Crosslinking ATP synthase complexes in vivo eliminates mitochondrial cristae. J Cell Sci 117:2333-2343.
52. Gibbons C, Montgomery MG, Leslie AGW, Walker JE. 2000. The structure of the central stalk in bovine F (1)-ATPase at 2.4 Å resolution. Nat Struct Biol 7:1055-1061.
53. +-transporting subunit c of the F1F0ATP synthase. Biochemistry 37:8817-8824.
54. Gogol EP, Lucken U, Capaldi RA. 1987. The stalk connecting the F1 and F0 domains of ATP synthase visualized by electron microscopy of unstained specimens. FEBS Lett 219:274-278.
55. Grabar TB, Cain BD. 2003. Integration of b subunits of unequal lengths into F1F0-ATP synthase. J Biol Chem 278:34751-34756.
56. Groth G. 2002. Structure of spinach chloroplast F1-ATPase complexed with the phytopathogenic inhibitor tentoxin. Proc Natl Acad Sci USA 99:3464-3468.
57. Groth G, Pohl E. 2001. The structure of the chloroplast F1-ÅTPase at 3.2 A resolution. J Biol Chem 276:1345-1352.
58. Guerrieri F, Zanotti F, Capozza G, Colaianni G, Ronchi S, et al. 1991. Structural and functional characterization of subunits of the F0 sector of the mitochondrial F0F1-AT P synthase. Biochim Biophys Acta 1059:348-354.
59. Harris DA, Das AM. 1991. Control of mitochondrial ATP synthesis in the heart. Biochem J 280:561-573.
60. Hausrath AC, Gruber G, Matthews BW, Capaldi RA. 1999. Structural features of the gamma subunit of the Escherichia coli F (1) ATPase revealed by a 4.4-Å resolution map obtained by x-ray crystallography. Proc Natl Acad Sci USA 96:13697-13702.
61. Hekman C, Tomich JM, Hatefi Y. 1991. Mitochondrial ATP synthase complex. Membrane topography and stoichiometry of the F0 subunits. J Biol Chem 266:13564-13571.
62. Helfenbein KG, Ellis TP, Dieckmann CL, Tzagoloff A. 2003. ATP22, a nuclear gene required for expression of the F0 sector of mitochondrial ATPase in Saccharomyces cerevisiae. J Biol Chem 278:19751-19756.
63. Hoffmann GF, Zschocke J. 1999. Glutaric aciduria type I: From clinical, biochemical and molecular diversity to successful therapy. J Inherit Metab Dis 22:381-391.
64. Houstek J, Klement P, Floryk D, Antonicka H, Hermanska J, et al. 1999. A novel deficiency of mitochondrial ATPase of nuclear origin. Hum Mol Genet 8:1967-1974.
65. Houstek J, Mracek T, Vojtiskova A, Zeman J. 2004. Mitochondrial diseases and ATPase defects of nuclear origin. Biochim Biophys Acta 1658:115-121.
66. Jiang W, Fillingame RH. 1998. Interacting helical faces of subunits a and c in the F1Fo ATP synthase of Escherichia coli defined by disulfide cross-linking. Proc Natl Acad Sci USA 95:6607-6612.
67. Jiang W, Hermolin J, Fillingame RH. 2001. The preferred stoichiometry of c subunits in the rotary motor sector of Escherichia coli ATP synthase is 10. Proc Natl Acad Sci USA 98:4966-4971.
68. Kagawa R, Montgomery MG, Braig K, Leslie AG, Walker JE. 2004. The structure of bovine F (1)-ATPase inhibited by ADP and beryllium fluoride. EMBO J 23:2734-2744.
69. Kagawa Y, Racker E. 1966. Partial resolution of the enzymes catalyzing oxidative phosphorylation. IX. Reconstruction of oligomycin-sensitive adenosine triphosphatase. J Biol Chem 241:2467-2474.
70. Karrasch S, Walker JE. 1999. Novel features in the structure of bovine ATP synthase. J Mol Biol 290:379-384.
71. Kato-Yamada Y, Noji H, Yasuda R, Kinosita Jr, K Yoshida M. 1998. Direct observation of the rotation of epsilon subunit in F1-ATPase. J Biol Chem 273:19375-19377.
72. Krause F, Reifschneider NH, Goto S, Dencher NA. 2005. Active oligomeric ATP synthases in mammalian mitochondria. Biochem Biophys Res Commun 329:583-590.
73. Lebowitz MS, Pedersen PL. 1993. Regulation of the mitochondrial ATP synthase/ATPase complex: cDNA cloning, sequence, overexpression, and secondary structural characterization of a functional protein inhibitor. Arch Biochem Biophys 301:64-70.
74. Lefebvre-Legendre L, Vaillier J, Benabdelhak H, Velours J, Slonimski PP, et al. 2001. Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F (1)-ATPase in heat stress conditions. J Biol Chem 276:6789-6796.
75. Long JC, Wang S, Vik SB. 1998. Membrane topology of subunit a of the F1F0 ATP synthase as determined by labeling of unique cysteine residues. J Biol Chem 273:16235-16240.
76. Luciakova K, Kuzela S. 1984. Increased content of natural ATPase inhibitor in tumor mitochondria. FEBS Lett 177:85-88.
77. Mayr JA, Paul J, Pecina P, Kurnik P, Forster H, et al. 2004. Reduced respiratory control with ADP and changed pattern of respiratory chain enzymes as a result of selective deficiency of the mitochondrial ATP synthase. Pediatr Res 55:988-994.
78. McGeoch JE, Palmer DN. 1999. Ion pores made of mitochondrial ATP synthase subunit c in the neuronal plasma membrane and Batten disease. Mol Genet Metab 66:387-392.
79. McLachlin DT, Bestard JA, Dunn SD. 1998. The b and delta subunits of the Escherichia coli ATP synthase interact via residues in their C-terminal regions. J Biol Chem 273:15162-15168.
80. Menz RI, Walker JE, Leslie AG. 2001. Structure of bovine mitochondrial F (1)-ATPase with nucleotide bound to all three catalytic sites: Implications for the mechanism of rotary catalysis. Cell 106:331-341.
81. Miller MJ, Oldenburg M, Fillingame RH. 1990. The essential carboxyl group in subunit c of the F1F0 ATP synthase can be moved and H (+)-translocating function retained. Proc Natl Acad Sci 87:4900-4904.
82. Mimura H, Hashimoto T, Yoshida Y, Ichikawa N, Tagawa K. 1993. Binding of an intrinsic ATPase inhibitor to the interface between alpha- and beta-subunits of F1FoATPase upon de-energization of mitochondria. J Biochem 113:350-354.
83. Moser TL, Kenan DJ, Ashley TA, Roy JA, Goodman MD, et al. 2001. Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci USA 98:6656-6661.
84. Moser TL, Stack MS, Asplin I, Enghild JJ, Hojrup P, et al. 1999. Angiostatin binds ATP synthase on the surface of human endothelial cells. Proc Natl Acad Sci USA 96:2811-2816.
85. Nishio K, Iwamoto-Kihara A, Yamamoto A, Wada Y, Futai M. 2002. Subunit rotation of ATP synthase embedded in membranes: A or beta subunit rotation relative to the c subunit ring. Proc Natl Acad Sci USA 99:13448-13452.
86. Nishizaka T, Oiwa K, Noji H, Kimura S, Muneyuki E, et al. 2004. Chemomechanical coupling in F1-ATPase revealed by simultaneous observation of nucleotide kinetics and rotation. Nat Struct Mol Biol 11:142-148.
87. Noji H, Yasuda R, Yoshida M, Kinosita K. 1997. Direct observation of the rotation of F1-ATPase. Nature 386:299-302.
88. Ogilvie I, Aggeler R, Capaldi RA. 1997. Cross-linking of the delta subunit to one of the three alpha subunits has no effect on functioning, as expected if delta is a part of the stator that links the F1 and F0 parts of the Escherichia coli ATP synthase. J Biol Chem 272:16652-16656.
89. Orriss GL, Leslie AG, Braig K, Walker JE. 1998. Bovine F1-ATPase covalently inhibited with 4-chloro-7-nitrobenzofurazan: The structure provides further support for a rotary catalytic mechanism. Structure 6:831-837.
90. Palmer DN, Fearnley IM, Walker JE, Hall NA, Lake BD, et al. 1992. Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease). Am J Med Genet 42:561-567.
91. Panchenko MV, Vinogradov AD. 1985. Interaction between the mitochondrial ATP synthetase and ATPase inhibitor protein. Active/inactive slow pH-dependent transitions of the inhibitor protein. FEBS Lett 184:226-230.
92. Panke O, Gumbiowski K, Junge W, Engelbrecht S. 2000. F-ATPase: specific observation of the rotating c subunit oligomer of EF (o) EF (1). FEBS Lett 472:34-38.
93. Papa S, Xu T, Gaballo A, Zanotti F. 1999. Frontiers of cellular bioenergetics: Molecular biology, biochemistry and physiopathology. Papa S, Guerrieri F, Tager JM, editors. London, New York: Plenum Press; pp. 459-487.
94. Papa S, Zanotti F, Cocco T, Perrucci C, Candita C, et al. 1996. Identification of functional domains and critical residues in the adenosinetriphosphatase inhibitor protein of mitochondrial F0F1 ATP synthase. Eur J Biochem 240:461-467.
95. Papa S, Zanotti F, Gaballo A. 2000. The structural and functional connection between the catalytic and proton translocating sectors of the mitochondrial F1F0-ATP synthase. J Bioenerg Biomembr 32:401-411.
96. Pullman ME, Monroy GC. 1963. A naturally occurring inhibitor of mitochondrial adenosine triphosphatase. J Biol Chem 238:3762-3769.
97. Rastogi VK, Girvin ME. 1999. Structural changes linked to proton translocation by subunit c of the ATP synthase. Nature 402:263-268.
98. Rouslin W. 1991. Regulation of the mitochondrial ATPase in situ in cardiac muscle: Role of the inhibitor subunit. J Bioenerg Biomembr 23:873-888.
99. Rouslin W, Broge CW. 1996. IF1 function in situ in uncoupler-challenged ischemic rabbit, rat, and pigeon hearts. J Biol Chem 271:23638-23641.
100. Rubinstein J, Walker J. 2002. ATP synthase from Saccharomyces cerevisiae: Location of the OSCP subunit in the peripheral stalk region. J Mol Biol 321:613-619.
101. Rubinstein JL, Walker JE, Henderson R. 2003. Structure of the mitochondrial ATP synthase by electron cryomicroscopy. EMBO J 22:6182-6192.
102. Sabbert D, Engelbrecht S, Junge W. 1996. Intersubunit rotation in active F-ATPase. Nature 381:623-625.
103. Sambongi Y, Iko Y, Tanabe M, Omote H, Iwamoto-Kihara A, et al. 1999. Mechanical rotation of the c subunit oligomer in ATP synthase (F0F1): Direct observation. Science 286:1722-1724.
104. Schagger H, Pfeiffer K. 2000. Supercomplexes in the respiratory chains of yeast and mammalian mitochondria. EMBO J 19:1777-17783.
105. Schemidt RA, Qu J, Williams JR, Brusilow WS. 1998. Effects of carbon source on expression of F0 genes and on the stoichiometry of the c subunit in the F1F0 ATPase of Escherichia coli. J Bacteriol 180:3205-3208.
106. Schneider E, Altendorf K. 1987. Bacterial adenosine 50-triphosphate synthase (F1F0): Purification and reconstitution of F0 complexes and biochemical and functional characterization of their subunits. Microbiol Rev 51:477-497.
107. Seelert H, Poetsch A, Dencher NA, Engel A, Stahlberg H, et al. 2000. Structural biology. Proton-powered turbine of a plant motor. Nature 405:418-419.
108. Senior AE, Nadanaciva S, Weber J. 2002. The molecular mechanism of ATP synthesis by F1F0-ATP synthase. Biochim Biophys Acta 1553:188-211.
109. Sergeant N, Wattez A, Galvan-valencia M, Ghestem A, David JP, et al. 2003. Association of ATP synthase alpha-chain with neurofibrillary degeneration in Alzheimer's disease. Neuroscience 117:293-303.
110. Shimabukuro K, Yasuda R, Muneyuki E, Hara KY, Kinosita K Jr, et al. 2003. Catalysis and rotation of F1 motor: Cleavage of ATP at the catalytic site occurs in 1 ms before 40 degree substep rotation. Proc Natl Acad Sci USA 100:14731-14736.
111. Shirakihara Y, Leslie AG, Abrahams JP, Walker JE, Ueda T, et al. 1997. The crystal structure of the nucleotide-free alpha 3 beta 3 subcomplex of F1-ATPase from the thermophilic Bacillus PS3 is a symmetric trimer. Structure 5:825-836.
112. Singh S, Turina P, Bustamante CJ, Keller DJ, Capaldi R. 1996. Topographical structure of membrane-bound Escherichia coli F1F0 ATP synthase in aqueous buffer. FEBS Lett 397:30-34.
113. Sorgen PL, Bubb MR, Cain BD. 1999. Lengthening the second stalk of F (1) F (0) ATP synthase in Escherichia coli. J Biol Chem 274:36261-36266.
114. Sorgen PL, Caviston TL, Perry RC, Cain BD. 1998. Deletions in the second stalk of F1F0-ATP synthase in Escherichia coli. J Biol Chem 273:27873-27878.
115. Stock D, Leslie AGW, Walker JE. 1999. Molecular architecture of the rotary motor in ATP synthase. Science 286:1700-1705.
116. Takeyasu K, Omote H, Nettikadan S, Tokumasu F, Iwamoto-Kihara A, et al. 1996. Molecular imaging of Escherichia coli F0F1-ATPase in reconstituted membranes using atomic force microscopy. FEBS Lett 392:110-113.
117. Tomasetig L, Di Pancrazio F, Harris DA, Mavelli I, Lippe G. 2002. Dimerization of F0F1ATP synthase from bovine heart is independent from the binding of the inhibitor protein IF1. Biochim Biophys Acta 1556:133-141.
118. Tomashek JJ, Brusilow WS. 2000. Stoichiometry of energy coupling by proton-translocating ATPases: A history of variability. J Bioenerg Biomembr 32:493-500.
119. Tsunoda SP, Aggeler R, Yoshida M, Capaldi RA. 2001. Rotation of the c subunit oligomer in fully functional F1Fo ATP synthase. Proc Natl Acad Sci USA 98:898-902.
120. Ueno H, Suzuki T, Kinosita K Jr, Yoshida M. 2005. ATP-driven stepwise rotation of FoF1-ATP synthase. Proc Natl Acad Sci USA 102:1333-1338.
121. Ullrich K, Flott-Rahmel B, Schluff P, Musshoff U, Das A, et al. 1999. Glutaric aciduria type I: Pathomechanisms of neurodegeneration. J Inherit Metab Dis 22:392-403.
122. Valiyaveetil FI, Fillingame RH. 1997. On the role of Arg-210 and Glu-219 of subunit a in proton translocation by the Escherichia coli F0F1-ATP synthase. J Biol Chem 272:32635-32641.
123. van Raaij MJ, Abrahams JP, Leslie AG, Walker JE. 1996a. The structure of bovine F1-ATPase complexed with the antibiotic inhibitor aurovertin B. Proc Natl Acad Sci USA 93:6913-6917.
124. van Raaij MJ, Orriss GL, Montgomery MG, Runswick MJ, Fearnley IM, et al. 1996b. The ATPase inhibitor protein from bovine heart mitochondria: The minimal inhibitory sequence. Biochemistry 35:15618-15625.
125. Vik SB, Antonio BJ. 1994. A mechanism of proton translocation by F1Fo ATP synthases suggested by double mutant of the a subunit. J Biol Chem 269:30364-30369.
126. +-ATP synthase. J Mol Biol 321:307-316.
127. Wada T, Long JC, Zhang D, Vik SB. 1999. A novel labeling approach supports the five-transmembrane model of subunit a of the Escherichia coli ATP synthase. J Biol Chem 274:17353-17357.
128. Walker JE, Collinson IR. 1994. The role of the stalk in the coupling mechanism of F1F0-ATPases. FEBS Lett 346:39-43.
129. Watts SD, Zhang Y, Fillingame RH, Capaldi RA. 1995. The gamma subunit in the Escherichia coli ATP synthase complex (ECF1F0) extends through the stalk and contacts the c subunits of the F0 part. FEBS Lett 368:235-238.
130. Weber J, Senior AE. 2000. ATP synthase: What we know about ATP hydrolysis and what we do not know about ATP synthesis. Biochim Biophys Acta 1458:300-309.
131. Weber J, Senior AE. 2003. ATP synthesis driven by proton transport in F1F0-ATP synthase. FEBS Lett 545:61-70.
132. Weber J, Muharemagic A, Wilke-Mounts S, Senior AE. 2004a. Analysis of sequence determinants of F1Fo-ATP synthase in the N-terminal region of alpha subunit for binding of delta subunit. J Biol Chem 279:25673-25679.
133. Weber J, Wilke-Mounts S, Nadanaciva S, Senior AE. 2004b. Quantitative determination of direct binding of b subunit to F1 in Escherichia coli F1F0-ATP synthase. J Biol Chem 279:11253-11258.
134. Wilkens S, Capaldi RA. 1998. ATP synthase's second stalk comes into focus. Nature 393:429.
135. Wilkens S, Dunn SD, Chandler J, Dahlquist FW, Capaldi RA. 1997. Solution structure of the N-terminal domain of the delta subunit of the E.coli ATP synthase. Nat Struct Biol 4:198-201.
136. Xu T, Zanotti F, Gaballo A, Raho G, Papa S. 2000. F1 and F0 connections in the bovine mitochondrial ATP synthase: The role of the alpha subunit N-terminus, oligomycinsensitivity conferring protein (OCSP) and subunit d. Eur J Biochem 267:4445-4455.
137. Yamada EW, Huzel NJ. 1992. Distribution of the ATPase inhibitor proteins of mitochondria in mammalian tissues including fibroblasts from a patient with Luft's disease. Biochim Biophys Acta 1139:143-147.
138. Yasuda R, Noji H, Yoshida M, Kinosita K Jr, Itoh H. 2001. Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase. Nature 410:898-904.
139. +-ATPase as a functional part of the F0 moiety. FEBS Lett 237:9-14.
140. Zanotti F, Guerrieri F, Deckers-Hebestreit G, Fiermonte M, Altendorf K, et al. 1994. Cross-reconstitution studies with polypeptides of Escherichia coli and bovine heart mitochondrial F0F1 ATP synthase. Eur J Biochem 222:733-741.
141. Zanotti F, Raho G, Gaballo A, Papa S. 2004. Inhibitory and anchoring domains in the ATPase inhibitor protein IF1 of bovine heart mitochondrial ATP synthase. J Bioenerg Biomembr 36:447-457.
142. Zanotti F, Raho G, Vuolo R, Gaballo A, Papa F, et al. 2000. Functional domains of the ATPase inhibitor protein from bovine heart mitochondria. FEBS Lett 482:163-166.