Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens

Journal of General Virology

Volumn 95, Issue PART 6, 2014, Pages 1233-1243

  Trapp, Sascha ^a   Soubieux, Denis ^a,b   Marty, Hélène ^a   Esnault, Evelyne ^a   Hoffmann, Thomas W ^a,b   Chandenier, Margaux ^a,b   Lion, Adrien ^a   Kut, Emmanuel ^a   Quéré, Pascale ^a   Larcher, Thibaut ^c   Ledevin, Mireille ^c   Munier, Sandie ^d,e,f   Naffakh, Nadia ^d,e,f   Marc, Daniel ^a,b  

^a UR1282   (France)

^b CEMAGREF   (France)

^c LUNAM UNIVERSITÉ   (France)

^d Sorbonne Paris Cité   (France)

^e Institut Pasteur   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTRUCTURAL PROTEIN 1; RNA BINDING PROTEIN;

ARTICLE; CHICKEN; CORRELATION ANALYSIS; DUCK; EPITHELIUM CELL; GENE DELETION; GENE MUTATION; GENOTYPE; HONG KONG; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; VIRAL CLEARANCE; VIRUS REPLICATION; VIRUS VIRULENCE; ZYGOTE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CHICK EMBRYO; CHICKENS; CYTOKINES; DNA, VIRAL; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA IN BIRDS; INTERFERON TYPE I; LUNG; MICE; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; SEQUENCE DELETION; SPECIES SPECIFICITY; VIRAL LOAD; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 84900863752     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.063776-0     Document Type: Article

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