메뉴 건너뛰기




Volumn 5, Issue APR, 2014, Pages

Interactions of IgG1 CH2 and CH3 domains with FcRn

Author keywords

Antibody fragments; CH2 domain; CH3 domain; FcRn; Small size

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G1 ANTIBODY;

EID: 84900849421     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00146     Document Type: Article
Times cited : (37)

References (24)
  • 1
    • 84864148041 scopus 로고    scopus 로고
    • Therapeutic proteins
    • doi:10.1007/978-1-61779-921-1_1
    • Dimitrov DS. Therapeutic proteins. Methods Mol Biol (2012) 899:1-26. doi:10.1007/978-1-61779-921-1_1.
    • (2012) Methods Mol Biol , vol.899 , pp. 1-26
    • Dimitrov, D.S.1
  • 2
    • 33646352962 scopus 로고    scopus 로고
    • Potent antibody therapeutics by design
    • doi:10.1038/nri1837
    • Carter PJ. Potent antibody therapeutics by design. Nat Rev Immunol (2006) 6(5):343-57. doi:10.1038/nri1837.
    • (2006) Nat Rev Immunol , vol.6 , Issue.5 , pp. 343-357
    • Carter, P.J.1
  • 3
    • 54849403487 scopus 로고    scopus 로고
    • Single-domain antibodies as building blocks for novel therapeutics
    • doi:10.1016/j.coph.2008.07.006
    • Saerens D, Ghassabeh GH, Muyldermans S. Single-domain antibodies as building blocks for novel therapeutics. Curr Opin Pharmacol (2008) 8(5):600-8. doi:10.1016/j.coph.2008.07.006.
    • (2008) Curr Opin Pharmacol , vol.8 , Issue.5 , pp. 600-608
    • Saerens, D.1    Ghassabeh, G.H.2    Muyldermans, S.3
  • 4
    • 84900869871 scopus 로고    scopus 로고
    • Discovery of novel candidate therapeutics and diagnostics based on engineered human antibody domains
    • Chen W, Gong R, Ying T, Prabakaran P, Zhu Z, Feng Y, et al. Discovery of novel candidate therapeutics and diagnostics based on engineered human antibody domains. Curr Drug Discov Technol (2014) 11(1):28-40.
    • (2014) Curr Drug Discov Technol , vol.11 , Issue.1 , pp. 28-40
    • Chen, W.1    Gong, R.2    Ying, T.3    Prabakaran, P.4    Zhu, Z.5    Feng, Y.6
  • 6
    • 34548229364 scopus 로고    scopus 로고
    • FcRn: the neonatal Fc receptor comes of age
    • doi:10.1038/nri2155
    • Roopenian DC, Akilesh S. FcRn: the neonatal Fc receptor comes of age. Nat Rev Immunol (2007) 7(9):715-25. doi:10.1038/nri2155.
    • (2007) Nat Rev Immunol , vol.7 , Issue.9 , pp. 715-725
    • Roopenian, D.C.1    Akilesh, S.2
  • 7
    • 0034042660 scopus 로고    scopus 로고
    • Multiple roles for the major histocompatibility complex class I-related receptor FcRn
    • doi:10.1146/annurev.immunol.18.1.739
    • Ghetie V, Ward ES. Multiple roles for the major histocompatibility complex class I-related receptor FcRn. Annu Rev Immunol (2000) 18:739-66. doi:10.1146/annurev.immunol.18.1.739.
    • (2000) Annu Rev Immunol , vol.18 , pp. 739-766
    • Ghetie, V.1    Ward, E.S.2
  • 8
    • 80052598705 scopus 로고    scopus 로고
    • Neonatal Fc receptor and IgG-based therapeutics
    • doi:10.4161/mabs.3.5.16983
    • Kuo TT, Aveson VG. Neonatal Fc receptor and IgG-based therapeutics. MAbs (2011) 3(5):422-30. doi:10.4161/mabs.3.5.16983.
    • (2011) MAbs , vol.3 , Issue.5 , pp. 422-430
    • Kuo, T.T.1    Aveson, V.G.2
  • 9
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • doi:10.1056/NEJM199707173370301
    • Moreland LW, Baumgartner SW, Schiff MH, Tindall EA, Fleischmann RM, Weaver AL, et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med (1997) 337(3):141-7. doi:10.1056/NEJM199707173370301.
    • (1997) N Engl J Med , vol.337 , Issue.3 , pp. 141-147
    • Moreland, L.W.1    Baumgartner, S.W.2    Schiff, M.H.3    Tindall, E.A.4    Fleischmann, R.M.5    Weaver, A.L.6
  • 10
    • 84863447184 scopus 로고    scopus 로고
    • Pharmacokinetics of engineered human monomeric and dimeric CH2 domains
    • doi:10.4161/mabs.20652
    • Gehlsen K, Gong R, Bramhill D, Wiersma D, Kirkpatrick S, Wang Y, et al. Pharmacokinetics of engineered human monomeric and dimeric CH2 domains. MAbs (2012) 4(4):466-74. doi:10.4161/mabs.20652.
    • (2012) MAbs , vol.4 , Issue.4 , pp. 466-474
    • Gehlsen, K.1    Gong, R.2    Bramhill, D.3    Wiersma, D.4    Kirkpatrick, S.5    Wang, Y.6
  • 11
    • 84883404242 scopus 로고    scopus 로고
    • Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics
    • doi:10.1074/jbc.M113.484154
    • Ying T, Chen W, Feng Y, Wang Y, Gong R, Dimitrov DS. Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics. J Biol Chem (2013) 288(35):25154-64. doi:10.1074/jbc.M113.484154.
    • (2013) J Biol Chem , vol.288 , Issue.35 , pp. 25154-25164
    • Ying, T.1    Chen, W.2    Feng, Y.3    Wang, Y.4    Gong, R.5    Dimitrov, D.S.6
  • 12
    • 84861720642 scopus 로고    scopus 로고
    • Soluble monomeric IgG1 Fc
    • doi:10.1074/jbc.M112.368647
    • Ying T, Chen W, Gong R, Feng Y, Dimitrov DS. Soluble monomeric IgG1 Fc. J Biol Chem (2012) 287(23):19399-408. doi:10.1074/jbc.M112.368647.
    • (2012) J Biol Chem , vol.287 , Issue.23 , pp. 19399-19408
    • Ying, T.1    Chen, W.2    Gong, R.3    Feng, Y.4    Dimitrov, D.S.5
  • 13
    • 79960992429 scopus 로고    scopus 로고
    • Shortened engineered human antibody CH2 domains: increased stability and binding to the human neonatal Fc receptor
    • doi:10.1074/jbc.M111.254219
    • Gong R, Wang Y, Feng Y, Zhao Q, Dimitrov DS. Shortened engineered human antibody CH2 domains: increased stability and binding to the human neonatal Fc receptor. J Biol Chem (2011) 286(31):27288-93. doi:10.1074/jbc.M111.254219.
    • (2011) J Biol Chem , vol.286 , Issue.31 , pp. 27288-27293
    • Gong, R.1    Wang, Y.2    Feng, Y.3    Zhao, Q.4    Dimitrov, D.S.5
  • 14
    • 84864670122 scopus 로고    scopus 로고
    • Bispecific engineered antibody domains (nanoantibodies) that interact noncompetitively with an HIV-1 neutralizing epitope and FcRn
    • doi:10.1371/journal.pone.0042288
    • Gong R, Wang Y, Ying T, Dimitrov DS. Bispecific engineered antibody domains (nanoantibodies) that interact noncompetitively with an HIV-1 neutralizing epitope and FcRn. PLoS One (2012) 7(8):e42288. doi:10.1371/journal.pone.0042288.
    • (2012) PLoS One , vol.7 , Issue.8
    • Gong, R.1    Wang, Y.2    Ying, T.3    Dimitrov, D.S.4
  • 15
    • 77954638589 scopus 로고    scopus 로고
    • Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties
    • doi:10.1093/protein/gzq005
    • Wozniak-Knopp G, Bartl S, Bauer A, Mostageer M, Woisetschlager M, Antes B, et al. Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties. Protein Eng Des Sel (2010) 23(4):289-97. doi:10.1093/protein/gzq005.
    • (2010) Protein Eng Des Sel , vol.23 , Issue.4 , pp. 289-297
    • Wozniak-Knopp, G.1    Bartl, S.2    Bauer, A.3    Mostageer, M.4    Woisetschlager, M.5    Antes, B.6
  • 16
    • 67649782189 scopus 로고    scopus 로고
    • Engineered human antibody constant domains with increased stability
    • doi:10.1074/jbc.M900769200
    • Gong R, Vu BK, Feng Y, Prieto DA, Dyba MA, Walsh JD, et al. Engineered human antibody constant domains with increased stability. J Biol Chem (2009) 284(21):14203-10. doi:10.1074/jbc.M900769200.
    • (2009) J Biol Chem , vol.284 , Issue.21 , pp. 14203-14210
    • Gong, R.1    Vu, B.K.2    Feng, Y.3    Prieto, D.A.4    Dyba, M.A.5    Walsh, J.D.6
  • 17
    • 84864135881 scopus 로고    scopus 로고
    • Expression, purification, and characterization of engineered antibody CH2 and VH domains
    • doi:10.1007/978-1-61779-921-1_6
    • Gong R, Chen W, Dimitrov DS. Expression, purification, and characterization of engineered antibody CH2 and VH domains. Methods Mol Biol (2012) 899:85-102. doi:10.1007/978-1-61779-921-1_6.
    • (2012) Methods Mol Biol , vol.899 , pp. 85-102
    • Gong, R.1    Chen, W.2    Dimitrov, D.S.3
  • 18
    • 79960111009 scopus 로고    scopus 로고
    • Design, expression and characterization of a soluble single-chain functional human neonatal Fc receptor
    • doi:10.1016/j.pep.2011.03.012
    • Feng Y, Gong R, Dimitrov DS. Design, expression and characterization of a soluble single-chain functional human neonatal Fc receptor. Protein Expr Purif (2011) 79(1):66-71. doi:10.1016/j.pep.2011.03.012.
    • (2011) Protein Expr Purif , vol.79 , Issue.1 , pp. 66-71
    • Feng, Y.1    Gong, R.2    Dimitrov, D.S.3
  • 19
    • 0035012654 scopus 로고    scopus 로고
    • Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding
    • doi:10.1016/S1097-2765(01)00230-1
    • Martin WL, West AP Jr, Gan L, Bjorkman PJ. Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding. Mol Cell (2001) 7(4):867-77. doi:10.1016/S1097-2765(01)00230-1.
    • (2001) Mol Cell , vol.7 , Issue.4 , pp. 867-877
    • Martin, W.L.1    West Jr., A.P.2    Gan, L.3    Bjorkman, P.J.4
  • 20
    • 61449229355 scopus 로고    scopus 로고
    • Protein structure homology modeling using SWISS-MODEL workspace
    • doi:10.1038/nprot.2008.197
    • Bordoli L, Kiefer F, Arnold K, Benkert P, Battey J, Schwede T. Protein structure homology modeling using SWISS-MODEL workspace. Nat Protoc (2009) 4(1):1-13. doi:10.1038/nprot.2008.197.
    • (2009) Nat Protoc , vol.4 , Issue.1 , pp. 1-13
    • Bordoli, L.1    Kiefer, F.2    Arnold, K.3    Benkert, P.4    Battey, J.5    Schwede, T.6
  • 22
    • 0038526303 scopus 로고    scopus 로고
    • ZDOCK: an initial-stage protein-docking algorithm
    • doi:10.1002/prot.10389
    • Chen R, Li L, Weng Z. ZDOCK: an initial-stage protein-docking algorithm. Proteins (2003) 52(1):80-7. doi:10.1002/prot.10389.
    • (2003) Proteins , vol.52 , Issue.1 , pp. 80-87
    • Chen, R.1    Li, L.2    Weng, Z.3
  • 23
    • 0029878720 scopus 로고    scopus 로고
    • VMD: visual molecular dynamics
    • doi:10.1016/0263-7855(96)00018-5
    • Humphrey W, Dalke A, Schulten K. VMD: visual molecular dynamics. J Mol Graph (1996) 14(1):33-8. doi:10.1016/0263-7855(96)00018-5.
    • (1996) J Mol Graph , vol.14 , Issue.1 , pp. 33-38
    • Humphrey, W.1    Dalke, A.2    Schulten, K.3
  • 24
    • 34548232365 scopus 로고    scopus 로고
    • Inference of macromolecular assemblies from crystalline state
    • doi:10.1016/j.jmb.2007.05.022
    • Krissinel E, Henrick K. Inference of macromolecular assemblies from crystalline state. J Mol Biol (2007) 372(3):774-97. doi:10.1016/j.jmb.2007.05.022.
    • (2007) J Mol Biol , vol.372 , Issue.3 , pp. 774-797
    • Krissinel, E.1    Henrick, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.