Low-dose primaquine for falciparum malaria

The Lancet Infectious Diseases

Volumn 14, Issue 6, 2014, Pages 449-

  Goyal, Kapil ^a   Kaur, Hargobinder ^a   Sehgal, Rakesh ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

8 AMINOQUINOLINE DERIVATIVE; CYTOCHROME P450 2D6; PRIMAQUINE; ANTIMALARIAL AGENT;

AFRICA; ALLELE; ASIA; DRUG EFFICACY; DRUG METABOLISM; DRUG POTENCY; DRUG TREATMENT FAILURE; ETHNIC DIFFERENCE; GENOTYPE; HUMAN; LETTER; LOW DRUG DOSE; MALARIA FALCIPARUM; MUTATION; PACIFIC ISLANDS; PHENOTYPE; PRIORITY JOURNAL; SOUTH AFRICA; TREATMENT RESPONSE; UGANDA; FEMALE; MALE; NOTE;

ANTIMALARIALS; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; PRIMAQUINE;

EID: 84900841501     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(14)70775-3     Document Type: Letter

References (5)

1. Eziefula AC, Bousema T, Yeung S, et al. Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis 2014, 14:130-139.
2. Steketee RW, ter Kuile F Single low-dose primaquine to reduce malaria transmission. Lancet Infect Dis 2014, 14:91-92.
3. Updated WHO policy recommendation (October 2012): single dose primaquine as a gametocytocide in Plasmodium falciparum malaria. October, 2012 2012, WHO, World Health Organization, Geneva.
4. WHO Evidence Review Group: the safety and effectiveness of single dose primaquine as a P. falciparum gametocytocide WHO, (accessed Sept 19, 2013). http://www.who.int/malaria/mpac/sep2012/primaquine_single_dose_pf_erg_meeting_report_aug2012.pdf.
5. D'Alessandro S, Silvestrini F, Dechering K, et al. A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection. J Antimicrob Chemother 2013, 68:2048-2058.