A short 2 week dose titration regimen reduces the severity of flu-like symptoms with initial interferon gamma-1b treatment

Current Medical Research and Opinion

Volumn 30, Issue 6, 2014, Pages 1179-1187

  Devane, John G ^a   Martin, Mary L ^a   Matson, Mark A ^b  

^a Vidara Therapeutics Research Ltd Adelaide Chambers   (Ireland)

^b Prism Research Inc   (United States)

Author keywords

Dose titration; Fever; Flu like symptoms; Interferon gamma 1b; Tolerance

Indexed keywords

GAMMA1B INTERFERON; PARACETAMOL; GAMMA INTERFERON; RECOMBINANT PROTEIN;

ADULT; ARTICLE; CHILL; CONSCIOUSNESS DISORDER; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE REGIMEN; DRUG DOSE TITRATION; DRUG FEVER; DRUG SAFETY; FATIGUE; FEMALE; FEVER; FLU LIKE SYNDROME; HEADACHE; HUMAN; HUMAN EXPERIMENT; INJECTION SITE ERYTHEMA; INJECTION SITE INDURATION; INJECTION SITE PAIN; INJECTION SITE REACTION; LEUKOCYTE COUNT; MALE; MYALGIA; NAUSEA AND VOMITING; NEUTROPENIA; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; RECOMMENDED DRUG DOSE; SIDE EFFECT; TRAUMATIC BRAIN INJURY; TREATMENT DURATION; UPPER RESPIRATORY TRACT INFECTION; ADOLESCENT; CHEMICALLY INDUCED; DRUG ADMINISTRATION; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; MIDDLE AGED; PAIN; SUBCUTANEOUS DRUG ADMINISTRATION; YOUNG ADULT;

ADOLESCENT; ADULT; DRUG ADMINISTRATION SCHEDULE; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FATIGUE; FEMALE; FEVER; HUMANS; INJECTIONS, SUBCUTANEOUS; INTERFERON-GAMMA; MALE; MIDDLE AGED; PAIN; RECOMBINANT PROTEINS; YOUNG ADULT;

EID: 84900809991     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007995.2014.899209     Document Type: Article

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