Effect of health protective factors on health deficit accumulation and mortality risk in older adults in the Beijing longitudinal study of aging

Journal of the American Geriatrics Society

Volumn 62, Issue 5, 2014, Pages 821-828

  Wang, Chunxiu ^a   Song, Xiaowei ^b,c   Mitnitski, Arnold ^b   Fang, Xianghua ^a   Tang, Zhe ^a   Yu, Pulin ^d   Rockwood, Kenneth ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b DALHOUSIE UNIVERSITY   (Canada)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d BEIJING HOSPITAL   (China)

Author keywords

aging; frailty; frailty index; health transitions; protection index

Indexed keywords

AGED; AGING; ARTICLE; CENTER FOR EPIDEMIOLOGICAL STUDIES DEPRESSION SCALE; CHINA; COHORT ANALYSIS; DAILY LIFE ACTIVITY; EDUCATIONAL STATUS; EXERCISE; FEMALE; FOLLOW UP; FRAILTY INDEX; HEALTH DEFICIT; HEALTH STATUS; HUMAN; LONGEVITY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; MORTALITY; POPULATION DYNAMICS; PROSPECTIVE STUDY; PROTECTION INDEX; RURAL POPULATION; SECONDARY ANALYSIS; SURVIVAL; URBAN POPULATION;

AGING; FRAILTY; FRAILTY INDEX; HEALTH TRANSITIONS; PROTECTION INDEX;

AGED; AGING; CHINA; FEMALE; FOLLOW-UP STUDIES; FRAIL ELDERLY; GERIATRIC ASSESSMENT; HEALTH STATUS; HUMANS; MALE; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; RURAL POPULATION; SEX FACTORS; SURVIVAL ANALYSIS; SURVIVAL RATE; URBAN POPULATION;

EID: 84900797809     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.12792     Document Type: Article

References (36)

1. Rockwood K, Fox RA, Stolee P, et al. Frailty in elderly people: An evolving concept. Can Med Assoc J 1994; 150: 489-495.
2. Clegg A, Young J, Iliffe S, et al. Frailty in elderly people. Lancet 2013; 381: 752-762.
3. Mitnitski AB, Mogilner AJ, Rockwood K,. Accumulation of deficits as a proxy measure of aging. ScientificWorldJournal 2001; 1: 323-336.
4. Goggins WB, Woo J, Sham A, et al. Frailty index as a measure of biological age in a Chinese population. J Gerontol A Biol Sci Med Sci 2005; 60A: 1046-1051.
5. Woo J, Goggins W, Sham A, et al. Social determinants of frailty. Gerontology 2005; 51: 402-408.
6. Mitnitski A, Song X, Skoog I, et al. Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc 2005; 53: 2184-2189.
7. Song X, MacKnight C, Latta R, et al. Frailty and survival of rural and urban seniors: Results from the Canadian Study of Health and Aging. Aging Clin Exp Res 2007; 19: 145-153.
8. Song X, Mitnitski A, Rockwood K,. Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geriatr Soc 2010; 58: 681-687.
9. Hubbard RE, Searle SD, Mitnitski A, et al. Effect of smoking on the accumulation of deficits, frailty and survival in older adults: A secondary analysis from the Canadian Study of Health and Aging. J Nutr Health Aging 2009; 13: 468-472.
10. Shi J, Song X, Yu P, et al. Analysis of frailty and survival from late middle age in the Beijing Longitudinal Study of Ageing. BMC Geriatr 2011; 20: 11-17.
11. Yu P, Song X, Shi J, et al. Frailty and survival of older Chinese adults in urban and rural areas: Results from the Beijing Longitudinal Study of Aging. Arch Gerontol Geriatr 2012; 54: 3-8.
12. Wang C, Song X, Mitnitski A, et al. Gender differences in the relationship between smoking and frailty: Results from the Beijing Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci 2013; 68A: 338-346.
13. Mitnitski A, Song X, Rockwood K,. Assessing biological aging: The origin of deficit accumulation. Biogerontology 2013; 14: 709-717.
14. Howlett SE, Rockwood K,. New horizons in frailty: Ageing and the deficit scaling problem. Age Ageing 2013; 42: 416-423.
15. Tang Z, Wang C, Song X, et al. Co-occurrence of cardiometabolic diseases and frailty in older Chinese adults in the Beijing Longitudinal Study of Ageing. Age Ageing 2013; 42: 346-351.
16. Li H, Li QD, Wang MS, et al. Smoking and air pollution exposure and lung cancer mortality in Zhaoyuan County. Int J Hyg Environ Health 2013; 216: 63-70.
17. Yang L, Zhou M, Sherliker P, et al. Alcohol drinking and overall and cause-specific mortality in China: Nationally representative prospective study of 220,000 men with 15 years of follow-up. Int J Epidemiol 2012; 41: 1101-1113.
18. Gu D, Kelly TN, Wu X, et al. Mortality attributable to smoking in China. N Engl J Med 2009; 360: 150-159.
19. Mitnitski A, Bao L, Rockwood K,. Going from bad to worse: A stochastic model of transitions in deficit accumulation, in relation to mortality. Mech Ageing Dev 2006; 127: 490-493.
20. Mitnitski A, Song X, Rockwood K,. Improvement and decline in health status from late middle age: Modeling age-related changes in deficit accumulation. Exp Gerontol 2007; 42: 1109-1115.
21. Fallah N, Mitnitski A, Searle SD, et al. Transitions in frailty status in older adults in relation to mobility: A multistate modeling approach employing a deficit count. J Am Geriatr Soc 2011; 59: 524-529.
22. Weiner MW, Aisen PS, Jack CR Jr, et al. The Alzheimer's disease neuroimaging initiative: Progress report and future plans. Alzheimers Dement 2010; 6: 202-211.
23. Song X, Mitnitski A, Zhang N, et al. Dynamics of brain structure and cognitive function in the Alzheimer's disease neuroimaging initiative. J Neurol Neurosurg Psychiatry 2013; 84: 71-78.
24. Andrew MK, Mitnitski AB, Rockwood K,. Social vulnerability, frailty and mortality in elderly people. PLoS ONE 2008; 3: e2232.
25. Kushner RF, Sorensen KW,. Lifestyle medicine: The future of chronic disease management. Curr Opin Endocrinol Diabetes Obes 2013; 20: 389-395.
26. Tanner LM, Moffatt S, Milne EM, et al. Socioeconomic and behavioural risk factors for adverse winter health and social outcomes in economically developed countries: A systematic review of quantitative observational studies. J Epidemiol Community Health 2013; 67: 1061-1067.
27. Tang Z, Wang HX, Meng C, et al. The prevalence of functional disability in activities of daily living and instrumental activities of daily living among elderly Beijing Chinese. Arch Gerontol Geriatr 1999; 29: 115-125.
28. Searle SD, Mitnitski A, Gahbauer EA, et al. A standard procedure for creating a frailty index. BMC Geriatr 2008; 8: 24.
29. Hubbard RE, Fallah N, Searle SD, et al. Impact of exercise in community dwelling older adults. PLoS ONE 2009; 4: e6174.
30. Rockwood K, Rockwood MR, Mitnitski A,. Physiological redundancy in older adults in relation to the change with age in the slope of a frailty index. J Am Geriatr Soc 2010; 58: 318-323.
31. Manini TM, Everhart JE, Patel KV, et al. Daily activity energy expenditure and mortality among older adults. JAMA 2006; 296: 171-179.
32. Binder EF, Schechtman KB, Ehsani AA, et al. Effects of exercise training on frailty in community-dwelling older adults: Results of a randomized, controlled trial. J Am Geriatr Soc 2002; 50: 1921-1928.
33. Paterson DH, Jones GR, Rice CL,. Aging and physical activity data on which to base recommendations for exercise in older adults. Appl Physiol Nutr Metab 2007; 2F: S75-S171.
34. Gill TM, Gahbauer EA, Allore HG, et al. Transitions between frailty states among community-living older persons. Arch Intern Med 2006; 166: 418-423.
35. Gill TM, Baker DI, Gottschalk M, et al. A program to prevent functional decline in physically frail, elderly persons who live at home. N Engl J Med 2002; 347: 1068-1074.
36. Mitnitski A, Bao L, Skoog I, et al. A cross-national study of transitions in deficit counts in two birth cohorts: Implications for modeling ageing. Exp Gerontol 2007; 42: 241-246.