The variations of VP1 protein might be associated with nervous system symptoms caused by enterovirus 71 infection

BMC Infectious Diseases

Volumn 14, Issue 1, 2014, Pages

  Zhang, Bao ^a   Wu, Xianbo ^a   Huang, Keyong ^a   Li, Ling ^a   Zheng, Li ^a   Wan, Chengsong ^a   He, Ming Liang ^b   Zhao, Wei ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

EV71; Neurovirulence; Variation; VP1

Indexed keywords

AMINO ACID; PROTEIN VP1; VIRUS PROTEIN;

ARTICLE; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; GENETIC VARIABILITY; GENOTYPE; INFECTIOUS COMPLICATION; MUTATIONAL ANALYSIS; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHYLOGENETIC TREE CONSTRUCTION METHOD; RISK ASSESSMENT; SEQUENCE ALIGNMENT; VIRAL TROPISM; VIRUS STRAIN; VIRUS VIRULENCE; AMINO ACID SUBSTITUTION; ENTEROVIRUS; GENETICS; HUMAN; NERVOUS SYSTEM; PATHOGENICITY; PHYLOGENY; VIROLOGY;

AMINO ACID SUBSTITUTION; ENTEROVIRUS; ENTEROVIRUS INFECTIONS; GENETIC VARIATION; GENOTYPE; HUMANS; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; PHYLOGENY; VIRAL STRUCTURAL PROTEINS;

EID: 84900547685     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-14-243     Document Type: Article

References (32)

1. Huang HI, Weng KF, Shih SR. Viral and host factors that contribute to pathogenicity of enterovirus 71. Future Microbiol 2012, 7(4):467-479. 10.2217/fmb.12.22, 22439724.
2. Lan YC, Lin TH, Tsai JD, Yang YC, Peng CT, Shih MC, Lin YJ, Lin CW. Molecular epidemiology of the 2005 enterovirus 71 outbreak in central Taiwan. Scand J Infect Dis 2011, 43(5):354-359. 10.3109/00365548.2010.545995, 21231813.
3. Bek EJ, McMinn PC. The pathogenesis and prevention of encephalitis due to human enterovirus 71. Curr Infect Dis Rep 2012, 14(4):397-407. 10.1007/s11908-012-0267-3, 22639066.
4. Wang SM, Lei HY, Yu CK, Wang JR, Su IJ, Liu CC. Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis 2008, 198(7):1002-1006. 10.1086/591462, 18710325.
5. Hamaguchi T, Fujisawa H, Sakai K, Okino S, Kurosaki N, Nishimura Y, Shimizu H, Yamada M. Acute encephalitis caused by intrafamilial transmission of enterovirus 71 in adult. Emerg Infect Dis 2008, 14(5):828-830. 10.3201/eid1405.071121, 2600258, 18439374.
6. Fan X, Jiang J, Liu Y, Huang X, Wang P, Liu L, Wang J, Chen W, Wu W, Xu B. Detection of human enterovirus 71 and Coxsackievirus A16 in an outbreak of hand, foot, and mouth disease in Henan Province, China in 2009. Virus Genes 2013, 46(1):1-9. 10.1007/s11262-012-0814-x, 23080402.
7. Ryu WS, Kang B, Hong J, Hwang S, Kim J, Cheon DS. Clinical and etiological characteristics of enterovirus 71-related diseases during a recent 2-year period in Korea. J Clin Microbiol 2010, 48(7):2490-2494. 10.1128/JCM.02369-09, 2897491, 20463159.
8. Huang YP, Lin TL, Hsu LC, Chen YJ, Tseng YH, Hsu CC, Fan WB, Yang JY, Chang FY, Wu HS. Genetic diversity and C2-like subgenogroup strains of enterovirus 71, Taiwan, 2008. Virol J 2010, 7:277. 10.1186/1743-422X-7-277, 2975644, 20959020.
9. Chua KB, Kasri AR. Hand foot and mouth disease due to enterovirus 71 in Malaysia. Virol Sin 2011, 26(4):221-228. 10.1007/s12250-011-3195-8, 21847753.
10. Wu Y, Yeo A, Phoon MC, Tan EL, Poh CL, Quak SH, Chow VT. The largest outbreak of hand; foot and mouth disease in Singapore in 2008: the role of enterovirus 71 and coxsackievirus A strains. Int J Infect Dis 2010, 14(12):e1076-e1081. 10.1016/j.ijid.2010.07.006, 20952237.
11. Honkanen H, Oikarinen S, Pakkanen O, Ruokoranta T, Pulkki MM, Laitinen OH, Tauriainen S, Korpela S, Lappalainen M, Vuorinen T, Haapala AM, Veijola R, Simell O, Ilonen J, Knip M, Hyöty H. Human enterovirus 71 strains in the background population and in hospital patients in Finland. J Clin Virol 2013, 56(4):348-353. 10.1016/j.jcv.2012.11.018, 23261080.
12. Zhang Y, Tan X, Cui A, Mao N, Xu S, Zhu Z, Zhou J, Shi J, Zhao Y, Wang X, Huang X, Zhu S, Zhang Y, Tang W, Ling H, Xu W. Complete genome analysis of the c4 subgenotype strains of enterovirus 71: predominant recombination c4 viruses persistently circulating in china for 14 years. PLoS One 2013, 8(2):e56341. 10.1371/journal.pone.0056341, 3575343, 23441179.
13. Lee MS, Tseng FC, Wang JR, Chi CY, Chong P, Su IJ. Challenges to licensure of enterovirus 71 vaccines. PLoS Negl Trop Dis 2012, 6(8):e1737. 10.1371/journal.pntd.0001737, 3429393, 22953003.
14. Chan YF, Wee KL, Chiam CW, Khor CS, Chan SY, Amalina WM, Sam IC. Comparative genetic analysis of VP4, VP1 and 3D gene regions of enterovirus 71 and coxsackievirus A16 circulating in Malaysia between 1997-2008. Trop Biomed 2012, 29(3):451-466.
15. Mirand A, Schuffenecker I, Henquell C, Billaud G, Jugie G, Falcon D, Mahul A, Archimbaud C, Terletskaia-Ladwig E, Diedrich S, Huemer HP, Enders M, Lina B, Peigue-Lafeuille H, Bailly JL. Phylogenetic evidence for a recent spread of two populations of human enterovirus 71 in European countries. J Gen Virol 2010, 91(Pt 9):2263-2277.
16. Chan YF, Sam IC, AbuBakar S. Phylogenetic designation of enterovirus 71 genotypes and subgenotypes using complete genome sequences. Infect Genet Evol 2010, 10(3):404-412. 10.1016/j.meegid.2009.05.010, 19465162.
17. Cordey S, Petty TJ, Schibler M, Martinez Y, Gerlach D, van Belle S, Turin L, Zdobnov E, Kaiser L, Tapparel C. Identification of site-specific adaptations conferring increased neural cell tropism during human enterovirus 71 infection. PLoS Pathog 2012, 8(7):e1002826. 10.1371/journal.ppat.1002826, 3406088, 22910880.
18. Li R, Zou Q, Chen L, Zhang H, Wang Y. Molecular analysis of virulent determinants of enterovirus 71. PLoS One 2011, 6(10):e26237. 10.1371/journal.pone.0026237, 3198388, 22039449.
19. Perez-Velez CM, Anderson MS, Robinson CC, McFarland EJ, Nix WA, Pallansch MA, Oberste MS, Glode MP. Outbreak of neurologic enterovirus type 71 disease: a diagnostic challenge. Clin Infect Dis 2007, 45(8):950-957. 10.1086/521895, 17879907.
20. Ryu WS, Kang B, Hong J, Hwang S, Kim A, Kim J, Cheon DS. Enterovirus 71 infection with central nervous system involvement, South Korea. Emerg Infect Dis 2010, 16(11):1764-1766. 10.3201/eid1611.100104, 3294506, 21029539.
21. Herrero LJ, Lee CS, Hurrelbrink RJ, Chua BH, Chua KB, McMinn PC. Molecular epidemiology of enterovirus 71 in peninsular Malaysia, 1997-2000. Arch Virol 2003, 148(7):1369-1385. 10.1007/s00705-003-0100-2, 12827466.
22. Ooi MH, Wong SC, Podin Y, Akin W, Del SS, Mohan A, Chieng CH, Perera D, Clear D, Wong D, Blake E, Cardosa J, Solomon T. Human enterovirus 71 disease in Sarawak, Malaysia: a prospective clinical, virological, and molecular epidemiological study. Clin Infect Dis 2007, 44(5):646-656. 10.1086/511073, 17278054.
23. Lu J, He YQ, Yi LN, Zan H, Kung HF, He ML. Viral kinetics of enterovirus 71 in human abdomyosarcoma cells. World J Gastroenterol 2011, 17(36):4135-4142. 10.3748/wjg.v17.i36.4135, 3203367, 22039330.
24. Miyamura K, Nishimura Y, Abo M, Wakita T, Shimizu H. Adaptive mutations in the genomes of enterovirus 71 strains following infection of mouse cells expressing human P-selectin glycoprotein ligand-1. J Gen Virol 2011, 92(Pt 2):287-291. 3081077, 20943886.
25. Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, Takemura T, Koike S. Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nat Med 2009, 15(7):798-801. 10.1038/nm.1992, 19543282.
26. Su PY, Liu YT, Chang HY, Huang SW, Wang YF, Yu CK, Wang JR, Chang CF. Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells. BMC Microbiol 2012, 12:162. 10.1186/1471-2180-12-162, 3478995, 22853823.
27. Yang B, Chuang H, Yang KD. Sialylated glycans as receptor and inhibitor of enterovirus 71 infection to DLD-1 intestinal cells. Virol J 2009, 6:141. 10.1186/1743-422X-6-141, 2751754, 19751532.
28. Tan CW, Poh CL, Sam IC, Chan YF. Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor. J Virol 2013, 87(1):611-620. 10.1128/JVI.02226-12, 3536405, 23097443.
29. Wang X, Zhu JP, Zhang Q, Xu ZG, Zhang F, Zhao ZH, Zheng WZ, Zheng LS. Detection of enterovirus 71 using reverse transcription loop-mediated isothermal amplification (RT-LAMP). J Virol Methods 2012, 179(2):330-334. 10.1016/j.jviromet.2011.11.019, 22155579.
30. Plevka P, Perera R, Cardosa J, Kuhn RJ, Rossmann MG. Crystal structure of human enterovirus 71. Science 2012, 336(6086):1274. 10.1126/science.1218713, 3448362, 22383808.
31. Zaini Z, McMinn P. A single mutation in capsid protein VP1 (Q145E) of a genogroup C4 strain of human enterovirus 71 generates a mouse-virulent phenotype. J Gen Virol 2012, 93(Pt 9):1935-1940.
32. Tee KK, Lam TT, Chan YF, Bible JM, Kamarulzaman A, Tong CY, Takebe Y, Pybus OG. Evolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene. J Virol 2010, 84(7):3339-3350. 10.1128/JVI.01019-09, 2838098, 20089660.