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Volumn 30, Issue 6, 2014, Pages 472-478

The subjective psychoactive effects of oral dronabinol studied in a randomized, controlled crossover clinical trial for pain

Author keywords

Abuse potential; Addiction; Cannabinoid; Dronabinol; Marijuana

Indexed keywords

AMPHETAMINE; CANNABIS; DRONABINOL; HYDROCODONE; HYDROMORPHONE; METHADONE; MORPHINE; OXYCODONE; PLACEBO; ANALGESIC AGENT; MEDICAL CANNABIS; NARCOTIC ANALGESIC AGENT; PSYCHOTROPIC AGENT;

EID: 84900540243     PISSN: 07498047     EISSN: 15365409     Source Type: Journal    
DOI: 10.1097/AJP.0000000000000022     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 84900561041 scopus 로고    scopus 로고
    • Available at Accessed May 30
    • World Drug Report 2011, Cannabis market. Available at: Http://www.unodc.org/documents/data-and-analysis/WDR2011/The-cannabis-market. pdf. Accessed May 30, 2013.
    • (2013) World Drug Report 2011, Cannabis Market
  • 2
    • 34548523508 scopus 로고    scopus 로고
    • History of cannabis and its preparations in saga, science, and sobriquet
    • Russo EB. History of cannabis and its preparations in saga, science, and sobriquet. Chem Biodivers. 2007;4:1614-1648.
    • (2007) Chem Biodivers , vol.4 , pp. 1614-1648
    • Russo, E.B.1
  • 3
    • 33947489961 scopus 로고
    • Isolation, structure, and partial synthesis of an active constituent of hashish
    • Gaoni Y, Mechoulam R. Isolation, structure, and partial synthesis of an active constituent of hashish. J Am Chem Soc. 1964;86:1646-1647.
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 4
    • 84900544392 scopus 로고    scopus 로고
    • Solvay Pharmaceut icals Inc Available at Accessed May 9, 2013
    • Solvay Pharmaceut icals Inc. Marinols Prescribing Information, 2006. Available at: Http://www.accessdata.fda.gov/drugsatfda-docs/label/2006/ 018651s025s026lbl.pdf. Accessed May 9, 2013.
    • (2006) Marinols Prescribing Information
  • 5
    • 84900535112 scopus 로고    scopus 로고
    • RotECoDDEAodais-iAf. A ssessment of dronabinol and its stereo-isomers Available at Accessed May 30
    • RotECoDDEAodais-iAf. A ssessment of dronabinol and its stereo-isomers. Available at: Http://who.int/medicines/areas/quality-safety/4. 2DronabinolCritReview.pdf. Accessed May 30, 2012.
    • (2012)
  • 6
    • 0032100491 scopus 로고    scopus 로고
    • The enhancement of morphine antinociception in mice by delta9-tetrahydrocannabinol
    • Smith FL, Cichewicz D, Martin ZL, et al. The enhancement of morphine antinociception in mice by delta9-tetrahydrocannabinol. Pharmacol Biochem Behav. 1998;60:559-566.
    • (1998) Pharmacol Biochem Behav , vol.60 , pp. 559-566
    • Smith, F.L.1    Cichewicz, D.2    Martin, Z.L.3
  • 7
    • 0032925678 scopus 로고    scopus 로고
    • Enhancement mu opioid antinociception by oral delta9- tetrahydrocannabinol: Dose-response analysis and receptor identification
    • Cichewicz DL, Martin ZL, Smith FL, et al. Enhancement mu opioid antinociception by oral delta9-tetrahydrocannabinol: Dose-response analysis and receptor identification. J Pharmacol Exp Ther. 1999;289:859-867.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 859-867
    • Cichewicz, D.L.1    Martin, Z.L.2    Smith, F.L.3
  • 8
    • 0037373238 scopus 로고    scopus 로고
    • Antinociceptive synergy between delta (9)-tetrahydrocannabinol and opioids after oral administration
    • Cichewicz DL, Mc Carthy EA. Antinociceptive synergy between delta(9)-tetrahydrocannabinol and opioids after oral administration. J Pharmacol Exp Ther. 2003;304:1010-1015.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1010-1015
    • Cichewicz, D.L.1    McCarthy, E.A.2
  • 9
    • 0346099153 scopus 로고    scopus 로고
    • Synergistic interactions between cannabinoid and opioid analgesics
    • Cichewicz DL. Synergistic interactions between cannabinoid and opioid analgesics. Life Sci. 2004;74:1317-1324.
    • (2004) Life Sci , vol.74 , pp. 1317-1324
    • Cichewicz, D.L.1
  • 10
    • 39549091694 scopus 로고    scopus 로고
    • Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy
    • Narang S, Gibson D, Wasan AD, et al. Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy. J Pain. 2008;9:254-264.
    • (2008) J Pain , vol.9 , pp. 254-264
    • Narang, S.1    Gibson, D.2    Wasan, A.D.3
  • 11
    • 20444399468 scopus 로고    scopus 로고
    • Molecular and cellular basis of cannabinoid and opioid interactions
    • Viganò D, Rubino T, Parolaro D. Molecular and cellular basis of cannabinoid and opioid interactions. Pharmacol Biochem Behav. 2005;81:360-368.
    • (2005) Pharmacol Biochem Behav , vol.81 , pp. 360-368
    • Vigano, D.1    Rubino, T.2    Parolaro, D.3
  • 12
    • 33845344400 scopus 로고    scopus 로고
    • Endocannabinoid mechanisms of pain modulation
    • Hohmann AG, Suplita RL. Endocannabinoid mechanisms of pain modulation. AAPS J. 2006;8:E693-E708.
    • (2006) AAPS J , vol.8
    • Hohmann, A.G.1    Suplita, R.L.2
  • 13
    • 0026410805 scopus 로고
    • Utility of subjective-effects measurements in assessing abuse liability of drugs in humans
    • Fischman MW, Foltin RW. Utility of subjective-effects measurements in assessing abuse liability of drugs in humans. Br J Addict. 1991;86:1563-1570.
    • (1991) Br J Addict , vol.86 , pp. 1563-1570
    • Fischman, M.W.1    Foltin, R.W.2
  • 14
    • 21744446711 scopus 로고    scopus 로고
    • Transdermal nicotine alters some of marihuana's effects in male and female volunteers
    • Penetar DM, Kouri EM, Gross MM, et al. Transdermal nicotine alters some of marihuana's effects in male and female volunteers. Drug Alcohol Depend. 2005;79:211-223.
    • (2005) Drug Alcohol Depend , vol.79 , pp. 211-223
    • Penetar, D.M.1    Kouri, E.M.2    Gross, M.M.3
  • 15
    • 26444598586 scopus 로고    scopus 로고
    • Reinforcing effects of oral Delta9-THC in male marijuana smokers in a laboratory choice procedure
    • Hart CL, Haney M, Vosburg SK, et al. Reinforcing effects of oral Delta9-THC in male marijuana smokers in a laboratory choice procedure. Psychopharmacology (Berl). 2005;181: 237-243.
    • (2005) Psychopharmacology (Berl , vol.181 , pp. 237-243
    • Hart, C.L.1    Haney, M.2    Vosburg, S.K.3
  • 16
    • 0032006542 scopus 로고    scopus 로고
    • Effects of expectancies on subjective responses to oral delta9-tetrahydrocannabinol
    • Kirk JM, Doty P, De Wit H. Effects of expectancies on subjective responses to oral delta9-tetrahydrocannabinol. Pharmacol Biochem Behav. 1998;59:287-293.
    • (1998) Pharmacol Biochem Behav , vol.59 , pp. 287-293
    • Kirk, J.M.1    Doty, P.2    De Wit, H.3
  • 17
    • 0026579386 scopus 로고
    • Reinforcing and subjective effects of oral delta 9-THC and smoked marijuana in humans
    • Chait LD,Zacny JP, Reinforcing and subjective effects of oral delta 9-THC and smoked marijuana in humans, Psychopharmacology (Berl,1992,107, 255-262.
    • (1992) Psychopharmacology (Berl , vol.107 , pp. 255-262
    • Chait, L.D.1    Zacny, J.P.2
  • 18
    • 0035987114 scopus 로고    scopus 로고
    • Comparison o f the subjective effects of Delta (9)-tetrahydrocannabinol and marijuana in humans
    • Wachtel SR, ElSohly MA, Ross SA, et al. Comparison o f the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans. Psychopharmacology (Berl). 2002; 161:331-339.
    • (2002) Psychopharmacology (Berl) , vol.161 , pp. 331-339
    • Wachtel, S.R.1    Elsohly, M.A.2    Ross, S.A.3
  • 19
    • 0036453750 scopus 로고    scopus 로고
    • Comparison of smoked marijuana and oral delta (9)-tetrahydrocannabinol in humans
    • Hart CL, Ward AS, Haney M, et al. Comparison of smoked marijuana and oral delta(9)-tetrahydrocannabinol in humans. Psychopharmacology (Berl). 2002;164:407-415.
    • (2002) Psychopharmacology (Berl , vol.164 , pp. 407-415
    • Hart, C.L.1    Ward, A.S.2    Haney, M.3
  • 21
    • 76249132039 scopus 로고    scopus 로고
    • The abuse potential of the synthetic cannabinoid nabilone
    • Ware MA St, Arnaud-Trempe E. The abuse potential of the synthetic cannabinoid nabilone. Addiction. 2010;105: 494-503.
    • (2010) Addiction , vol.105 , pp. 494-503
    • Ware, M.A.S.T.1    Arnaud-Trempe, E.2
  • 22
    • 80051985532 scopus 로고    scopus 로고
    • Abuse potential and psychoactive effects of d-9- tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine
    • Robson P. Abuse potential and psychoactive effects of d-9- tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine. Expert Opin Drug Saf. 2011;10:675-685.
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 675-685
    • Robson, P.1
  • 23
    • 84900531499 scopus 로고    scopus 로고
    • SAMHSA Fact sheet: National Household survey on Drug Abuse, 2011 Available at
    • SAMHSA Fact sheet: National Household survey on Drug Abuse, 2011. Available at: Http://www.samhsa.gov/data/NSDUH/2k10NSDUH/2k10Results.htm#5.3. Accessed June 6, 2013.
    • (2013) Accessed June 6
  • 24
    • 0026643378 scopus 로고
    • Drug abuse, dependence, and addiction in chronic pain patients
    • Fishbain DA, Rosomoff HL, Rosomoff RS. Drug abuse, dependence, and addiction in chronic pain patients. Clin J Pain. 1992;8:77-85.
    • (1992) Clin J Pain , vol.8 , pp. 77-85
    • Fishbain, D.A.1    Rosomoff, H.L.2    Rosomoff, R.S.3
  • 25
    • 0018777651 scopus 로고
    • Drug abuse and dependency in patients with chronic pain
    • Maruta T, Swanson DW, Finlayson RE. Drug abuse and dependency in patients with chronic pain. Mayo Clin Proc. 1979;54:241-244.
    • (1979) Mayo Clin Proc , vol.54 , pp. 241-244
    • Maruta, T.1    Swanson, D.W.2    Finlayson, R.E.3
  • 26
    • 0020037077 scopus 로고
    • Self-reported vs. Actual use of medications in chronic pain patients
    • Ready LB, Sarkis E, Turner JA. Self-reported vs. actual use of medications in chronic pain patients. Pain. 1982;12:285-294.
    • (1982) Pain , vol.12 , pp. 285-294
    • Ready, L.B.1    Sarkis, E.2    Turner, J.A.3
  • 27
    • 5644303369 scopus 로고    scopus 로고
    • Validation of a screener and opioid assessment measure for patients with chronic pain
    • Butler SF, Budman SH, Fernandez K, et al. Validation of a screener and opioid assessment measure for patients with chronic pain. Pain. 2004;112:65-75.
    • (2004) Pain , vol.112 , pp. 65-75
    • Butler, S.F.1    Budman, S.H.2    Fernandez, K.3
  • 28
    • 34247523880 scopus 로고    scopus 로고
    • Development and validation of the Current Opioid Misuse Measure
    • Bu tler SF, Budman SH, Fernandez KC, et al. Development and validation of the Current Opioid Misuse Measure. Pain. 2007;130:144-156.
    • (2007) Pain , vol.130 , pp. 144-156
    • Butler, S.F.1    Budman, S.H.2    Fernandez, K.C.3
  • 29
    • 0016425051 scopus 로고
    • Analgesic effect of delta-9-tetrahydrocannabinol
    • Noyes R, Brunk SF, Baram DA, et al. Analgesic effect of delta-9-tetrahydrocannabinol. J Clin Pharmacol. 1975;15: 139-143.
    • (1975) J Clin Pharmacol , vol.15 , pp. 139-143
    • Noyes, R.1    Brunk, S.F.2    Baram, D.A.3
  • 30
    • 0028261433 scopus 로고
    • Interactions between delta 9- tetrahydrocannabinol and kappa opioids in mice
    • Smith PB, Welch SP, Martin BR. Interactions between delta 9- tetrahydrocannabinol and kappa opioids in mice. J Pharmacol Exp Ther. 1994;268:1381-1387.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1381-1387
    • Smith, P.B.1    Welch, S.P.2    Martin, B.R.3
  • 31
    • 44249114538 scopus 로고    scopus 로고
    • Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination products
    • Zacny JP, Gutierrez S. Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination products. Pain Med. 2008;9:433-443.
    • (2008) Pain Med , vol.9 , pp. 433-443
    • Zacny, J.P.1    Gutierrez, S.2


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