-
2
-
-
80052466157
-
Current paradigms and evolving concepts in metastatic castration-resistant prostate cancer
-
Pal SK, Sartor O. Current paradigms and evolving concepts in metastatic castration-resistant prostate cancer. Asian J Androl 2011; 13: 683-9
-
(2011)
Asian J Androl
, vol.13
, pp. 683-689
-
-
Pal, S.K.1
Sartor, O.2
-
3
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR, Horti J, Pluzanska A, et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004; 351: 1502-12
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
-
4
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, Hussain MH, Lara PN Jr, Jones JA, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004; 351: 1513-20
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
Lara Jr., P.N.4
Jones, J.A.5
-
5
-
-
84900469485
-
-
Available from Last accessed on 2011 Jul 03
-
FDA approval for docetaxel. Available from: Http://www.cancer.gov/ cancertopics/ druginfo/fda-docetaxel. [Last accessed on 2011 Jul 03
-
FDA Approval for Docetaxel
-
-
-
6
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: Randomised open-label trial
-
de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: Randomised open-label trial. Lancet 2010; 376: 1147-54
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
MacHiels, J.P.5
-
7
-
-
77749275124
-
-
Available from Last accessed on 2013 Jan 06
-
FDA approval letter: Cabazitaxel. Available from: Http://www.accessdata. fda. gov/drugsatfda-docs/nda/2010/201023s000Approv.pdf. [Last accessed on 2013 Jan 06
-
FDA Approval Letter: Cabazitaxel
-
-
-
8
-
-
77749275124
-
-
Available from Last accessed on 2013 Nov 23
-
FDA approval letter: Provenge. Available from: Http://www.cancer.gov/ cancertopics/ druginfo/fda-sipuleucel-T. [Last accessed on 2013 Nov 23
-
FDA Approval Letter: Provenge
-
-
-
9
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363: 411-22
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
-
10
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, Fizazi K, North S, et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 2011; 364: 1995-2005
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
-
11
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med 2013; 368: 138-48
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
Molina, A.4
Logothetis, C.J.5
-
12
-
-
84874991510
-
-
Available from Last accessed on 2012 Jan 06
-
FDA approval for abiraterone acetate. Available from: Http://www.cancer.gov/ cancertopics/druginfo/fda-Abirateroneacetate. [Last accessed on 2012 Jan 06
-
FDA Approval for Abiraterone Acetate
-
-
-
13
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher HI, Fizazi K, Saad F, Taplin ME, Sternberg CN, et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med 2012; 367: 1187-97
-
(2012)
N Engl J Med
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
Taplin, M.E.4
Sternberg, C.N.5
-
15
-
-
84874955602
-
-
Available from Last accessed on 2013 Jan 06
-
FDA approval for enzalutamide. Available from: Http://www.cancer.gov/ cancertopics/ druginfo/fda-enzalutamide. [Last accessed on 2013 Jan 06
-
FDA Approval for Enzalutamide
-
-
-
16
-
-
33746883985
-
Overview of samarium sm 153 lexidronam in the treatment of painful metastatic bone disease
-
Sartor O. Overview of samarium sm 153 lexidronam in the treatment of painful metastatic bone disease. Rev Urol 2004; 6 Suppl 10: S3-12
-
(2004)
Rev Urol
, vol.6
, Issue.SUPPL. 10
-
-
Sartor, O.1
-
17
-
-
0025781809
-
A prospective, randomised double-blind crossover study to examine the efficacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone
-
Lewington VJ, McEwan AJ, Ackery DM, Bayly RJ, Keeling DH, et al. A prospective, randomised double-blind crossover study to examine the efficacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone. Eur J Cancer 1991; 27: 954-8
-
(1991)
Eur J Cancer
, vol.27
, pp. 954-958
-
-
Lewington, V.J.1
McEwan, A.J.2
Ackery, D.M.3
Bayly, R.J.4
Keeling, D.H.5
-
18
-
-
0028580148
-
Strontium-89 (Metastron) in the treatment of prostate cancer metastatic to bone
-
Porter AT. Strontium-89 (Metastron) in the treatment of prostate cancer metastatic to bone. Eur Urol 1994; 26 Suppl 1: 20-5
-
(1994)
Eur Urol
, vol.26
, Issue.SUPPL. 1
, pp. 20-25
-
-
Porter, A.T.1
-
19
-
-
84880428467
-
Alpha emitter radium-223 and survival in metastatic prostate cancer
-
Parker C, Nilsson S, Heinrich D, Helle SI, O'Sullivan JM, et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. N Engl J Med 2013; 369: 213-23
-
(2013)
N Engl J Med
, vol.369
, pp. 213-223
-
-
Parker, C.1
Nilsson, S.2
Heinrich, D.3
Helle, S.I.4
O'sullivan, J.M.5
-
20
-
-
84900521100
-
-
Available from Last accessed on 2013 Nov 22
-
FDA approval leeter for xofigo. Available from: Http://www.accessdata. fda.gov/ drugsatfda-docs/appletter/2013/203971Orig1s000ltr.pdf. [Last accessed on 2013 Nov 22
-
FDA Approval Leeter for Xofigo
-
-
-
21
-
-
84873864130
-
Bone-Targeting radiopharmaceuticals including radium-223
-
Brady D, Parker CC, O'Sullivan JM. Bone-Targeting radiopharmaceuticals including radium-223. Cancer J 2013; 19: 71-8
-
(2013)
Cancer J
, vol.19
, pp. 71-78
-
-
Brady, D.1
Parker, C.C.2
O'sullivan, J.M.3
-
22
-
-
84872507131
-
Radium-223 chloride: Potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease
-
Harrison MR, Wong TZ, Armstrong AJ, George DJ. Radium-223 chloride: Potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease. Cancer Manag Res 2013; 5: 1-14
-
(2013)
Cancer Manag Res
, vol.5
, pp. 1-14
-
-
Harrison, M.R.1
Wong, T.Z.2
Armstrong, A.J.3
George, D.J.4
-
23
-
-
0034922587
-
A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer
-
Dafermou A, Colamussi P, Giganti M, Cittanti C, Bestagno M, et al. A multicentre observational study of radionuclide therapy in patients with painful bone metastases of prostate cancer. Eur J Nucl Med 2001; 28: 788-98
-
(2001)
Eur J Nucl Med
, vol.28
, pp. 788-798
-
-
Dafermou, A.1
Colamussi, P.2
Giganti, M.3
Cittanti, C.4
Bestagno, M.5
-
24
-
-
0036606104
-
Significant antitumor effect from bone-seeking, alpha-particle-emitting (223) Ra demonstrated in an experimental skeletal metastases model
-
Henriksen G, Breistø. K, Bruland Ø.S, Fodstad Ø., Larsen RH. Significant antitumor effect from bone-seeking, alpha-particle- emitting (223) Ra demonstrated in an experimental skeletal metastases model. Cancer Res 2002; 62: 3120-5
-
(2002)
Cancer Res
, vol.62
, pp. 3120-3125
-
-
Henriksen, G.1
Breistø, K.2
Bruland, ØS.3
Fodstad Ø4
Larsen, R.H.5
-
25
-
-
0037315930
-
Targeting of osseous sites with alpha-emitting 223Ra: Comparison with the beta-emitter 89Sr in mice
-
Henriksen G, Fisher DR, Roeske JC, Bruland ø.S, Larsen RH. Targeting of osseous sites with alpha-emitting 223Ra: Comparison with the beta-emitter 89Sr in mice. J Nucl Med 2003; 44: 252-9
-
(2003)
J Nucl Med
, vol.44
, pp. 252-259
-
-
Henriksen, G.1
Fisher, D.R.2
Roeske, J.C.3
Bruland, ØS.4
Larsen, R.H.5
-
26
-
-
20644447798
-
First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases
-
Nilsson S, Larsen RH, Foss SD, Balteskard L, Borch KW, et al. First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases. Clin Cancer Res 2005; 11: 4451-9
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4451-4459
-
-
Nilsson, S.1
Larsen, R.H.2
Foss, S.D.3
Balteskard, L.4
Borch, K.W.5
-
27
-
-
84881630281
-
Phase i pharmacokinetic and biodistribution study with escalating doses of 223Ra-dichloride in men with castration-resistant metastatic prostate cancer
-
Carrasquillo JA, O'Donoghue JA, Pandit-Taskar N, Humm JL, Rathkopf DE, et al. Phase I pharmacokinetic and biodistribution study with escalating doses of 223Ra-dichloride in men with castration-resistant metastatic prostate cancer. Eur J Nucl Med Mol Imaging 2013; 40: 1384-93
-
(2013)
Eur J Nucl Med Mol Imaging
, vol.40
, pp. 1384-1393
-
-
Carrasquillo, J.A.1
O'donoghue, J.A.2
Pandit-Taskar, N.3
Humm, J.L.4
Rathkopf, D.E.5
-
28
-
-
34347244905
-
Bone-Targeted radium-223 in symptomatic, hormone-refractory prostate cancer: Randomised, multicentre, placebo-controlled phase II study
-
Nilsson S, Franzé. L, Parker C, Tyrrell C, Blom R, et al. Bone-Targeted radium-223 in symptomatic, hormone-refractory prostate cancer: Randomised, multicentre, placebo-controlled phase II study. Lancet Oncol 2007; 8: 587-94
-
(2007)
Lancet Oncol
, vol.8
, pp. 587-594
-
-
Nilsson, S.1
Franzé Parker L, C.2
Tyrrell, C.3
Blom, R.4
-
29
-
-
84874543674
-
Two-year survival follow-up of the randomized, double-blind, placebo-controlled phase II study of radium-223 chloride in patients with castration-resistant prostate cancer and bone metastases
-
Nilsson S, Franzé. L, Parker C, Tyrrell C, Blom R, et al. Two-year survival follow-up of the randomized, double-blind, placebo-controlled phase II study of radium-223 chloride in patients with castration-resistant prostate cancer and bone metastases. Clin Genitourin Cancer 2013; 11: 20-6
-
(2013)
Clin Genitourin Cancer
, vol.11
, pp. 20-26
-
-
Nilsson, S.1
Franzé, L.2
Parker, C.3
Tyrrell, C.4
Blom, R.5
-
30
-
-
84858706749
-
Arandomized dose-response multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer
-
Nilsson S, Strang P, Aksnes AK, Franzé. L, Olivier P, et al. A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer. Eur J Cancer 2012; 48: 678-86
-
(2012)
Eur J Cancer
, vol.48
, pp. 678-686
-
-
Nilsson, S.1
Strang, P.2
Aksnes, A.K.3
Franzé, L.4
Olivier, P.5
-
31
-
-
84871926771
-
A randomized, double-blind, dose-finding, multicenter, phase 2 study of radium chloride (Ra 223) in patients with bone metastases and castration-resistant prostate cancer
-
Parker CC, Pascoe S, Chodacki A, O'Sullivan JM, Germ JR, et al. A randomized, double-blind, dose-finding, multicenter, phase 2 study of radium chloride (Ra 223) in patients with bone metastases and castration-resistant prostate cancer. Eur Urol 2013; 63: 189-97
-
(2013)
Eur Urol
, vol.63
, pp. 189-197
-
-
Parker, C.C.1
Pascoe, S.2
Chodacki, A.3
O'sullivan, J.M.4
Germ, J.R.5
-
32
-
-
84878197268
-
Updated analysis of radium-223 dichloride (ra-223 impact on skeletal-related events (sre in patients with castration-resistant prostate cancer (crpc) and bone metastases from the phase iii randomized trial (alsympca
-
Vogelzang NJ, Parker C, Nilsson S, Coleman RE, O'Bryan-Tear CG, et al. Updated analysis of radium-223 dichloride (Ra-223) impact on skeletal-related events (SRE in patients with castration-resistant prostate cancer (CRPC) and bone metastases from the phase III randomized trial (ALSYMPCA). ASCO Meeting Abstracts 2013; 31: 11
-
(2013)
ASCO Meeting Abstracts
, vol.31
, pp. 11
-
-
Vogelzang, N.J.1
Parker, C.2
Nilsson, S.3
Coleman, R.E.4
O'bryan-Tear, C.G.5
-
33
-
-
84864605856
-
Radium-223 chloride (Ra-223 impact on skeletal-related events (SREs) and ECOG performance status (PS) in patients with castration-resistant prostate cancer (CRPC) with bone metastases: Interim results of a phase III trial (ALSYMPCA)
-
Sartor AO, Heinrich D, O'Sullivan JM, Fossa SD, Chodacki A, et al. Radium-223 chloride (Ra-223) impact on skeletal-related events (SREs) and ECOG performance status (PS) in patients with castration-resistant prostate cancer (CRPC) with bone metastases: Interim results of a phase III trial (ALSYMPCA). ASCO Meeting Abstracts 2012; 30: 4551
-
(2012)
ASCO Meeting Abstracts
, vol.30
, pp. 4551
-
-
Sartor, A.O.1
Heinrich, D.2
O'sullivan, J.M.3
Fossa, S.D.4
Chodacki, A.5
-
34
-
-
84886261057
-
Correlation between baseline variables and survival in the radium-223 dichloride (Ra-223) phase III ALSYMPCA trial with attention to total ALP changes
-
Sartor AO, Amariglio R, Wilhelm S, Garcia-Vargas JE, O'Bryan-Tear CG, et al. Correlation between baseline variables and survival in the radium-223 dichloride (Ra-223) phase III ALSYMPCA trial with attention to total ALP changes ASCO Meeting Abstracts 2013; 31: 5080
-
(2013)
ASCO Meeting Abstracts
, vol.31
, pp. 5080
-
-
Sartor, A.O.1
Amariglio, R.2
Wilhelm, S.3
Garcia-Vargas, J.E.4
O'bryan-Tear, C.G.5
-
35
-
-
84898848548
-
1.5-year post-Treatment follow-up of radium-223 dichloride (Ra-223) in patients with castration-resistant prostate cancer (CRPC) and bone metastases from the phase 3 ALSYMPCA study
-
Nilsson S, Vogelzang NJ, Sartor AO, Bottomley D, Coleman RE, et al. 1.5-year post-Treatment follow-up of radium-223 dichloride (Ra-223) in patients with castration-resistant prostate cancer (CRPC) and bone metastases from the phase 3 ALSYMPCA study. ASCO Meeting Abstracts 2014; 32: 9
-
(2014)
ASCO Meeting Abstracts
, vol.32
, pp. 9
-
-
Nilsson, S.1
Vogelzang, N.J.2
Sartor, A.O.3
Bottomley, D.4
Coleman, R.E.5
-
36
-
-
84885761394
-
Efficacy and safety of radium-223 dichloride (Ra-223) in castration-resistant prostate cancer (CRPC) patients with bone metastases who did or did not receive prior docetaxel (D) in the phase III ALSYMPCA trial
-
Vogelzang NJ, Helle SI, Johannessen DC, O'Sullivan JM, Garcia-Vargas JE, et al. Efficacy and safety of radium-223 dichloride (Ra-223) in castration-resistant prostate cancer (CRPC) patients with bone metastases who did or did not receive prior docetaxel (D) in the phase III ALSYMPCA trial. ASCO Meeting Abstracts 2013; 31: 5068
-
(2013)
ASCO Meeting Abstracts
, vol.31
, pp. 5068
-
-
Vogelzang, N.J.1
Helle, S.I.2
Johannessen, D.C.3
O'sullivan, J.M.4
Garcia-Vargas, J.E.5
-
37
-
-
84900496398
-
Hematologic safety of radium-223 dichloride (ra-223) in the phase 3 alsympca trial in castration-resistant prostate cancer (crpc) patients with bone metastases:Baseline prognostic factor subgroup analysis
-
O'Sullivan J, Widmark DCJ, Syndikus I, James N, Dall'Oglio M, et al. Hematologic safety of radium-223 dichloride (Ra-223) in the phase 3 ALSYMPCA trial in castration-resistant prostate cancer (CRPC) patients with bone metastases:Baseline prognostic factor subgroup analysis. ESMO/ECCO Proc 2013; 49: S688
-
(2013)
ESMO/ECCO Proc
, vol.49
-
-
O'sullivan, J.1
Widmark, D.C.J.2
Syndikus, I.3
James, N.4
Dall'oglio, M.5
-
38
-
-
84886604050
-
Pain analyses from the phase III randomized ALSYMPCA study with radium-223 dichloride (Ra-223) in castration-resistant prostate cancer (CRPC) patients with bone metastases
-
Nilsson S, Sartor AO, Bruland OS, Fang F, Aksnes AK, et al. Pain analyses from the phase III randomized ALSYMPCA study with radium-223 dichloride (Ra-223) in castration-resistant prostate cancer (CRPC) patients with bone metastases ASCO Meeting Abstracts 2013; 31: 5038
-
(2013)
ASCO Meeting Abstracts
, vol.31
, pp. 5038
-
-
Nilsson, S.1
Sartor, A.O.2
Bruland, O.S.3
Fang, F.4
Aksnes, A.K.5
-
39
-
-
84874999296
-
-
Available from [Last accessed on 2013 Jan 04
-
Medivation press release: PREVAIL enrollment. Available from: Http://www. investors.medivation.com/releasedetail.cfm?.ReleaseID=680579. [Last accessed on 2013 Jan 04
-
Medivation Press Release: PREVAIL Enrollment
-
-
-
40
-
-
34547786581
-
Docetaxel and cisplatin in patients with metastatic androgen independent prostate cancer and circulating neuroendocrine markers
-
Culine S, El Demery M, Lamy PJ, Iborra F, Avanc̈. C, et al. Docetaxel and cisplatin in patients with metastatic androgen independent prostate cancer and circulating neuroendocrine markers. J Urol 2007; 178: 844-8
-
(2007)
J Urol
, vol.178
, pp. 844-848
-
-
Culine, S.1
El Demery, M.2
Lamy, P.J.3
Iborra, F.4
Avanc̈, C.5
-
41
-
-
84900510268
-
-
Available from Last accessed on 2013 Nov 24
-
Research to practice: Clinical use of radium-223 Available from: Http://www. researchtopractice.com/PCUTT112/Video/14. [Last accessed on 2013 Nov 24
-
Research to Practice: Clinical Use of radium-223
-
-
-
42
-
-
84875793215
-
Intermittent versus continuous androgen Deprivation in prostate cancer
-
Hussain M, Tangen CM, Berry DL, Higano CS, Crawford ED, et al. Intermittent versus continuous androgen Deprivation in prostate cancer. N Engl J Med 2013; 368: 1314-25
-
(2013)
N Engl J Med
, vol.368
, pp. 1314-1325
-
-
Hussain, M.1
Tangen, C.M.2
Berry, D.L.3
Higano, C.S.4
Crawford, E.D.5
-
43
-
-
84900503061
-
Safety of radium-223 dichloride (Ra-223) with docetaxel (D) in patients with bone metastases from castration-resistant prostate cancer (CRPC): Phase i Prostate Cancer Clinical Trials Consortium Study
-
Morris MJ, Hammers HJ, Sweeney C, Antonarakis ES, Cho SY, et al. Safety of radium-223 dichloride (Ra-223) with docetaxel (D) in patients with bone metastases from castration-resistant prostate cancer (CRPC): Phase I Prostate Cancer Clinical Trials Consortium Study. ASCO Meeting Abstracts 2013; 31: 5021.
-
(2013)
ASCO Meeting Abstracts
, vol.31
, pp. 5021
-
-
Morris, M.J.1
Hammers, H.J.2
Sweeney, C.3
Antonarakis, E.S.4
Cho, S.Y.5
|