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Volumn 65, Issue , 2014, Pages 263-278

Anti-B cell antibody therapies for inflammatory rheumatic diseases

Author keywords

B cell targeted therapy; Myositis; Rheumatoid arthritis; Sj gren's syndrome; Systemic lupus erythematosus; Vasculitis

Indexed keywords

ATACICEPT; B LYMPHOCYTE ANTIBODY; BELIMUMAB; CORTICOSTEROID; CYCLOPHOSPHAMIDE; EPRATUZUMAB; LEFLUNOMIDE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OCRELIZUMAB; OFATUMUMAB; PLACEBO; PREDNISONE; RITUXIMAB;

EID: 84900502132     PISSN: 00664219     EISSN: 1545326X     Source Type: Book Series    
DOI: 10.1146/annurev-med-070912-133235     Document Type: Review
Times cited : (32)

References (73)
  • 1
    • 84862315184 scopus 로고    scopus 로고
    • Immunotherapies in rheumatologic disorders
    • Miller AV, Ranatunga SK. 2012. Immunotherapies in rheumatologic disorders. Med. Clin. North Am. 96(3):475-96
    • (2012) Med. Clin. North Am , vol.96 , Issue.3 , pp. 475-496
    • Miller, A.V.1    Ranatunga, S.K.2
  • 2
    • 84855172814 scopus 로고    scopus 로고
    • The pathogenesis of rheumatoid arthritis
    • McInnes IB, Schett G. 2011. The pathogenesis of rheumatoid arthritis. N. Engl. J.Med. 365(23):2205-19
    • (2011) N. Engl. J.Med , vol.365 , Issue.23 , pp. 2205-2219
    • McInnes, I.B.1    Schett, G.2
  • 3
    • 38149138096 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and other rheumatic conditions in the United States
    • Helmick CG, Felson DT, Lawrence RC, et al. 2008. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. Arthritis Rheum. 58(1):15-25
    • (2008) Part I. Arthritis Rheum , vol.58 , Issue.1 , pp. 15-25
    • Helmick, C.G.1    Felson, D.T.2    Lawrence, R.C.3
  • 4
    • 56749171085 scopus 로고    scopus 로고
    • Why do people with rheumatoid arthritis still die prematurely?
    • Gabriel SE. 2008. Why do people with rheumatoid arthritis still die prematurely? Ann. Rheum. Dis. 67(Suppl. 3):iii30-34
    • (2008) Ann Rheum. Dis , vol.67 , Issue.SUPPL. 3
    • Gabriel, S.E.1
  • 5
    • 0035093233 scopus 로고    scopus 로고
    • Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes
    • Edwards JC, Cambridge G. 2001. Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes. Rheumatology (Oxford) 40(2):205-11
    • (2001) Rheumatology (Oxford) , vol.40 , Issue.2 , pp. 205-211
    • Edwards, J.C.1    Cambridge, G.2
  • 6
    • 2942537697 scopus 로고    scopus 로고
    • Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
    • Edwards JC, Szczepanski L, Szechinski J, et al. 2004. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N. Engl. J. Med. 350(25):2572-81
    • (2004) N. Engl. J. Med , vol.350 , Issue.25 , pp. 2572-2581
    • Edwards, J.C.1    Szczepanski, L.2    Szechinski, J.3
  • 8
    • 33646483031 scopus 로고    scopus 로고
    • The efficacy and safety of rituximab in patients with active rheumatoid arthritis despitemethotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
    • Emery P, Fleischmann R, Filipowicz-Sosnowska A, et al. 2006. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despitemethotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum. 54(5):1390-400
    • (2006) Arthritis Rheum , vol.54 , Issue.5 , pp. 1390-1400
    • Emery, P.1    Fleischmann, R.2    Filipowicz-Sosnowska, A.3
  • 9
    • 58849088519 scopus 로고    scopus 로고
    • Rituximab inhibits structural joint damage in patients with rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitor therapies
    • Keystone E, Emery P, Peterfy CG, et al. 2009. Rituximab inhibits structural joint damage in patients with rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitor therapies. Ann. Rheum. Dis. 68(2):216-21
    • (2009) Ann. Rheum. Dis , vol.68 , Issue.2 , pp. 216-221
    • Keystone, E.1    Emery, P.2    Peterfy, C.G.3
  • 10
    • 77953715791 scopus 로고    scopus 로고
    • Continued inhibition of structural damage over 2 years in patients with rheumatoid arthritis treated with rituximab in combination with methotrexate
    • Cohen SB, Keystone E, Genovese MC, et al. 2010. Continued inhibition of structural damage over 2 years in patients with rheumatoid arthritis treated with rituximab in combination with methotrexate. Ann. Rheum. Dis. 69(6):1158-61
    • (2010) Ann. Rheum. Dis , vol.69 , Issue.6 , pp. 1158-1161
    • Cohen, S.B.1    Keystone, E.2    Genovese, M.C.3
  • 11
    • 78650645377 scopus 로고    scopus 로고
    • Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: The IMAGE trial
    • Tak PP, Rigby WF, Rubbert-Roth A, et al. 2011. Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial. Ann. Rheum. Dis. 70(1):39-46
    • (2011) Ann. Rheum. Dis , vol.70 , Issue.1 , pp. 39-46
    • Tak, P.P.1    Rigby, W.F.2    Rubbert-Roth, A.3
  • 12
    • 84857233786 scopus 로고    scopus 로고
    • Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from the randomised controlled trial IMAGE
    • Tak PP, Rigby W, Rubbert-Roth A, et al. 2012. Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from the randomised controlled trial IMAGE. Ann. Rheum. Dis. 71(3):351-57
    • (2012) Ann. Rheum. Dis , vol.71 , Issue.3 , pp. 351-357
    • Tak, P.P.1    Rigby, W.2    Rubbert-Roth, A.3
  • 13
    • 77951777466 scopus 로고    scopus 로고
    • Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: Results from the SUNRISE trial
    • Mease PJ, Cohen S, Gaylis NB, et al. 2010. Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: results from the SUNRISE trial. J. Rheumatol. 37(5):917-27
    • (2010) J. Rheumatol , vol.37 , Issue.5 , pp. 917-927
    • Mease, P.J.1    Cohen, S.2    Gaylis, N.B.3
  • 14
    • 77955738274 scopus 로고    scopus 로고
    • Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: Results of a phase III randomized study (MIRROR)
    • Rubbert-Roth A, Tak PP, Zerbini C, et al. 2010. Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: results of a phase III randomized study (MIRROR). Rheumatology (Oxford) 49(9):1683-93
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.9 , pp. 1683-1693
    • Rubbert-Roth, A.1    Tak, P.P.2    Zerbini, C.3
  • 15
    • 77955896561 scopus 로고    scopus 로고
    • Efficacy and safety of different doses and retreatment of rituximab: A randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate. Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE)
    • Emery P, Deodhar A, Rigby WF, et al. 2010. Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate. Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE). Ann. Rheum. Dis. 69(9):1629-35
    • (2010) Ann. Rheum. Dis , vol.69 , Issue.9 , pp. 1629-1635
    • Emery, P.1    Deodhar, A.2    Rigby, W.F.3
  • 16
    • 79955806071 scopus 로고    scopus 로고
    • Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis
    • Buch MH, Smolen JS, Betteridge N, et al. 2011. Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis. Ann. Rheum. Dis. 70(6):909-20
    • (2011) Ann. Rheum. Dis , vol.70 , Issue.6 , pp. 909-920
    • Buch, M.H.1    Smolen, J.S.2    Betteridge, N.3
  • 17
    • 84875177703 scopus 로고    scopus 로고
    • Factors correlated with improvement of endothelial dysfunction during rituximab therapy in patients with rheumatoid arthritis
    • Benucci M, Saviola G, Manfredi M, et al. 2013. Factors correlated with improvement of endothelial dysfunction during rituximab therapy in patients with rheumatoid arthritis. Biologics 7:69-75
    • (2013) Biologics , vol.7 , pp. 69-75
    • Benucci, M.1    Saviola, G.2    Manfredi, M.3
  • 18
    • 84874400762 scopus 로고    scopus 로고
    • HDL protein composition alters from proatherogenic into less atherogenic and proinflammatory in rheumatoid arthritis patients responding to rituximab
    • Raterman HG, Levels H, Voskuyl AE, et al. 2013. HDL protein composition alters from proatherogenic into less atherogenic and proinflammatory in rheumatoid arthritis patients responding to rituximab. Ann. Rheum. Dis. 72(4):560-65
    • (2013) Ann. Rheum. Dis , vol.72 , Issue.4 , pp. 560-565
    • Raterman, H.G.1    Levels, H.2    Voskuyl, A.E.3
  • 19
    • 77955386129 scopus 로고    scopus 로고
    • Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized, double-blind, placebo-controlled, phase I/II study
    • OstergaardM, Baslund B, Rigby W, et al. 2010. Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: results of a randomized, double-blind, placebo-controlled, phase I/II study. Arthritis Rheum. 62(8):2227-38
    • (2010) Arthritis Rheum , vol.62 , Issue.8 , pp. 2227-2238
    • Ostergaard, M.1    Baslund, B.2    Rigby, W.3
  • 20
    • 84860390375 scopus 로고    scopus 로고
    • Ofatumumab, a fully human anti-CD20 monoclonal antibody, in biological-naive, rheumatoid arthritis patients with an inadequate response to methotrexate: A randomised, double-blind, placebo-controlled clinical trial
    • Taylor PC, Quattrocchi E, Mallett S, et al. 2011. Ofatumumab, a fully human anti-CD20 monoclonal antibody, in biological-naive, rheumatoid arthritis patients with an inadequate response to methotrexate: a randomised, double-blind, placebo-controlled clinical trial. Ann. Rheum. Dis. 70(12):2119-25
    • (2011) Ann. Rheum. Dis , vol.70 , Issue.12 , pp. 2119-2125
    • Taylor, P.C.1    Quattrocchi, E.2    Mallett, S.3
  • 21
    • 51849148443 scopus 로고    scopus 로고
    • Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patientswith rheumatoid arthritis: A phase I/II randomized, blinded, placebocontrolled, dose-ranging study
    • GenoveseMC, Kaine JL, Lowenstein MB, et al. 2008. Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patientswith rheumatoid arthritis: a phase I/II randomized, blinded, placebocontrolled, dose-ranging study. Arthritis Rheum. 58(9):2652-61
    • (2008) Arthritis Rheum , vol.58 , Issue.9 , pp. 2652-2661
    • Genovese, M.C.1    Kaine, J.L.2    Lowenstein, M.B.3
  • 22
    • 84856388514 scopus 로고    scopus 로고
    • Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a forty-eight-week randomized, doubleblind, placebo-controlled, parallel-group phase III trial
    • Rigby W, Tony HP, Oelke K, et al. 2012. Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a forty-eight-week randomized, doubleblind, placebo-controlled, parallel-group phase III trial. Arthritis Rheum. 64(2):350-59
    • (2012) Arthritis Rheum , vol.64 , Issue.2 , pp. 350-359
    • Rigby, W.1    Tony, H.P.2    Oelke, K.3
  • 23
    • 84863012323 scopus 로고    scopus 로고
    • Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: Results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial
    • Tak PP, Mease PJ, Genovese MC, et al. 2012. Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial. Arthritis Rheum. 64(2):360-70
    • (2012) Arthritis Rheum , vol.64 , Issue.2 , pp. 360-370
    • Tak, P.P.1    Mease, P.J.2    Genovese, M.C.3
  • 24
    • 84863841745 scopus 로고    scopus 로고
    • Safety and efficacy of ocrelizumab in combination with methotrexate in MTX-naive subjects with rheumatoid arthritis: The phase III FILM trial
    • Stohl W, Gomez-Reino J, Olech E, et al. 2012. Safety and efficacy of ocrelizumab in combination with methotrexate in MTX-naive subjects with rheumatoid arthritis: the phase III FILM trial. Ann. Rheum. Dis. 71(8):1289-96
    • (2012) Ann. Rheum. Dis , vol.71 , Issue.8 , pp. 1289-1296
    • Stohl, W.1    Gomez-Reino, J.2    Olech, E.3
  • 25
    • 84863229726 scopus 로고    scopus 로고
    • Safety and efficacy of various dosages of ocrelizumab in Japanese patients with rheumatoid arthritis with an inadequate response to methotrexate therapy: A placebocontrolled double-blind parallel-group study
    • HarigaiM, Tanaka Y, Maisawa S. 2012. Safety and efficacy of various dosages of ocrelizumab in Japanese patients with rheumatoid arthritis with an inadequate response to methotrexate therapy: a placebocontrolled double-blind parallel-group study. J. Rheumatol. 39(3):486-95
    • (2012) J. Rheumatol , vol.39 , Issue.3 , pp. 486-495
    • Harigaim Tanaka, Y.1    Maisawa, S.2
  • 26
    • 33646367770 scopus 로고    scopus 로고
    • Belimumab (BmAb), a fully human monoclonal antibody to B-lymphocyte stimulator (BLyS), combined with standard of care therapy reduces signs and symptoms of rheumatoid arthritis in a heterogenous subject population
    • McKay J, Chwalinska-Sadowska H, Boling E, et al. 2005. Belimumab (BmAb), a fully human monoclonal antibody to B-lymphocyte stimulator (BLyS), combined with standard of care therapy reduces signs and symptoms of rheumatoid arthritis in a heterogenous subject population. Arthritis Rheum. 52(9, Suppl.):710-11
    • (2005) Arthritis Rheum , vol.52 , Issue.9 SUPPL. , pp. 710-711
    • McKay, J.1    Chwalinska-Sadowska, H.2    Boling, E.3
  • 27
    • 38149114077 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis: Results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study
    • Tak PP, Thurlings RM, Rossier C, et al. 2008. Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study. Arthritis Rheum. 58(1):61-72
    • (2008) Arthritis Rheum , vol.58 , Issue.1 , pp. 61-72
    • Tak, P.P.1    Thurlings, R.M.2    Rossier, C.3
  • 28
    • 79959832697 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a phase II, randomized, placebo-controlled, dose-finding trial
    • Genovese MC, Kinnman N, de La Bourdonnaye G, et al. 2011. Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: results of a phase II, randomized, placebo-controlled, dose-finding trial. Arthritis Rheum. 63(7):1793-803
    • (2011) Arthritis Rheum , vol.63 , Issue.7 , pp. 1793-1803
    • Genovese, M.C.1    Kinnman, N.2    De La Bourdonnaye, G.3
  • 29
    • 79959856423 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo-controlled trial
    • van Vollenhoven RF, Kinnman N, Vincent E, et al. 2011. Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase II, randomized, placebo-controlled trial. Arthritis Rheum. 63(7):1782-92
    • (2011) Arthritis Rheum , vol.63 , Issue.7 , pp. 1782-1792
    • Van Vollenhoven, R.F.1    Kinnman, N.2    Vincent, E.3
  • 31
    • 0031052874 scopus 로고    scopus 로고
    • Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: Comparison with the Framingham Study
    • Manzi S, Meilahn EN, Rairie JE, et al. 1997. Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study. Am. J. Epidemiol. 145(5):408-15
    • (1997) Am. J. Epidemiol , vol.145 , Issue.5 , pp. 408-415
    • Manzi, S.1    Meilahn, E.N.2    Rairie, J.E.3
  • 32
    • 1842530440 scopus 로고    scopus 로고
    • Cardiovascular Disease a Hazard Despite Improved Prognosis in Patients with Systemic Lupus Erythematosus: Results from a Swedish Population Based Study 1964-95
    • Bjornadal L, Yin L, Granath F, et al. 2004. Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus: results from a Swedish population based study 1964-95. J. Rheumatol. 31(4):713-19 (Pubitemid 38451257)
    • (2004) Journal of Rheumatology , vol.31 , Issue.4 , pp. 713-719
    • Bjornadal, L.1    Yin, L.2    Granath, F.3    Klareskog, L.4    Ekbom, A.5
  • 33
    • 80155168896 scopus 로고    scopus 로고
    • High risk of ischemic heart disease in patients with lupus nephritis
    • FaurschouM, Mellemkjaer L, Starklint H, et al. 2011. High risk of ischemic heart disease in patients with lupus nephritis. J. Rheumatol. 38(11):2400-5
    • (2011) J. Rheumatol , vol.38 , Issue.11 , pp. 2400-2405
    • Faurschou, M.1    Mellemkjaer, L.2    Starklint, H.3
  • 35
    • 7844245772 scopus 로고    scopus 로고
    • A multicentre study of 513 Danish patients with systemic lupus erythematosus I.Disease manifestations and analyses of clinical subsets
    • Jacobsen S, Petersen J, Ullman S, et al. 1998. A multicentre study of 513 Danish patients with systemic lupus erythematosus. I.Disease manifestations and analyses of clinical subsets. Clin. Rheumatol. 17(6):468- 77
    • (1998) Clin. Rheumatol , vol.17 , Issue.6 , pp. 468-477
    • Jacobsen, S.1    Petersen, J.2    Ullman, S.3
  • 36
    • 44849112235 scopus 로고    scopus 로고
    • Current treatment of lupus nephritis
    • DOI 10.1177/0961203308090029, Proceedings of the 7th european Lupus Meeting
    • Houssiau FA, Ginzler EM. 2008. Current treatment of lupus nephritis. Lupus 17(5):426-30 (Pubitemid 351798721)
    • (2008) Lupus , vol.17 , pp. 426-430
    • Houssiau, F.A.1    Ginzler, E.M.2
  • 37
    • 84871838942 scopus 로고    scopus 로고
    • B cell elimination in systemic lupus erythematosus
    • Furtado J, Isenberg DA. 2013. B cell elimination in systemic lupus erythematosus. Clin. Immunol. 146(2):90-103
    • (2013) Clin. Immunol , vol.146 , Issue.2 , pp. 90-103
    • Furtado, J.1    Isenberg, D.A.2
  • 38
    • 74849131972 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in moderately-toseverely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
    • Merrill JT, Neuwelt CM, Wallace DJ, et al. 2010. Efficacy and safety of rituximab in moderately-toseverely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum. 62(1):222-33
    • (2010) Arthritis Rheum , vol.62 , Issue.1 , pp. 222-233
    • Merrill, J.T.1    Neuwelt, C.M.2    Wallace, D.J.3
  • 39
    • 84866184129 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The Lupus Nephritis Assessment with Rituximab study
    • Rovin BH, Furie R, Latinis K, et al. 2012. Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum. 64(4):1215-26
    • (2012) Arthritis Rheum , vol.64 , Issue.4 , pp. 1215-1226
    • Rovin, B.H.1    Furie, R.2    Latinis, K.3
  • 40
    • 84856364391 scopus 로고    scopus 로고
    • Efficacy and safety of ocrelizumab, a humanized antiCD20 antibody, in patients with active proliferative lupus nephritis (LN): Results from the randomized, doubleblind phase III BELONG study
    • Mysler EF, Spindler AJ, Guzman R, et al. 2010. Efficacy and safety of ocrelizumab, a humanized antiCD20 antibody, in patients with active proliferative lupus nephritis (LN): results from the randomized, doubleblind phase III BELONG study. Arthritis Rheum. 62(10, Suppl.):606-7
    • (2010) Arthritis Rheum , vol.62 , Issue.10 SUPPL. , pp. 606-607
    • Mysler, E.F.1    Spindler, A.J.2    Guzman, R.3
  • 41
    • 67651084006 scopus 로고    scopus 로고
    • Randomized controlled trials (RCTs) of epratuzumab (anti- CD22 mab targeting B-cells) reveal clinically meaningful improvements in patients (Pts) with moderate/severe SLE flares
    • Petri M, Hobbs K, Gordon C, et al. 2008. Randomized controlled trials (RCTs) of epratuzumab (anti- CD22 mab targeting B-cells) reveal clinically meaningful improvements in patients (Pts) with moderate/severe SLE flares. Ann. Rheum. Dis. 67(Suppl. II):53
    • (2008) Ann. Rheum. Dis , vol.67 , Issue.SUPPL. II , pp. 53
    • Petri, M.1    Hobbs, K.2    Gordon, C.3
  • 42
    • 67651110504 scopus 로고    scopus 로고
    • Randomized controlled trials of epratuzumab (anti-CD22 mab targeting B-cells) reveal clinically meaningful reductions in corticosteroid (CS) use with favorable safety profile in moderate and severe flaring SLE patients
    • Wallace D, Hobbs K, Houssiau F, et al. 2008. Randomized controlled trials of epratuzumab (anti-CD22 mab targeting B-cells) reveal clinically meaningful reductions in corticosteroid (CS) use with favorable safety profile in moderate and severe flaring SLE patients. Ann. Rheum. Dis. 67(Suppl. II):212
    • (2008) Ann. Rheum. Dis , vol.67 , Issue.SUPPL. II , pp. 212
    • Wallace, D.1    Hobbs, K.2    Houssiau, F.3
  • 43
    • 84889645482 scopus 로고    scopus 로고
    • Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: Results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study
    • Epub ahead of print
    • Wallace DJ, Kalunian K, Petri MA, et al. 2013. Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study. Ann. Rheum. Dis. Epub ahead of print.
    • (2013) Ann. Rheum. Dis
    • Wallace, D.J.1    Kalunian, K.2
  • 44
    • 82455198794 scopus 로고    scopus 로고
    • Aphase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patientswith systemic lupus erythematosus
    • FurieR, Petri M, Zamani O, et al. 2011.Aphase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patientswith systemic lupus erythematosus. Arthritis Rheum. 63(12):3918-30
    • (2011) Arthritis Rheum , vol.63 , Issue.12 , pp. 3918-3930
    • Furier Petri, M.1    Zamani, O.2
  • 45
    • 79952070370 scopus 로고    scopus 로고
    • Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised, placebo-controlled, phase 3 trial
    • Navarra SV, Guzman RM, Gallacher AE, et al. 2011. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial. Lancet 377(9767):721- 31
    • (2011) Lancet , vol.377 , Issue.9767 , pp. 721-731
    • Navarra, S.V.1    Guzman, R.M.2    Gallacher, A.E.3
  • 46
    • 84871574493 scopus 로고    scopus 로고
    • Effect of belimumab treatment on renal outcomes: Results from the phase 3 belimumab clinical trials in patients with SLE
    • Dooley MA, Houssiau F, Aranow C, et al. 2013. Effect of belimumab treatment on renal outcomes: results from the phase 3 belimumab clinical trials in patients with SLE. Lupus 22(1):63-72
    • (2013) Lupus , vol.22 , Issue.1 , pp. 63-72
    • Dooley, M.A.1    Houssiau, F.2    Aranow, C.3
  • 47
    • 84856795563 scopus 로고    scopus 로고
    • Atacicept in combination with MMF and corticosteroids in lupus nephritis: Results of a prematurely terminated trial
    • Ginzler EM, Wax S, Rajeswaran A, et al. 2012. Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial. Arthritis Res. Ther. 14(1):R33
    • (2012) Arthritis Res. Ther , vol.14 , Issue.1
    • Ginzler, E.M.1    Wax, S.2    Rajeswaran, A.3
  • 48
    • 84871251698 scopus 로고    scopus 로고
    • 2012 revised International Chapel Hill ConsensusConference Nomenclature of Vasculitides
    • Jennette JC, Falk RJ, Bacon PA, et al. 2013. 2012 revised International Chapel Hill ConsensusConference Nomenclature of Vasculitides. Arthritis Rheum. 65(1):1-11
    • (2013) Arthritis Rheum , vol.65 , Issue.1 , pp. 1-11
    • Jennette, J.C.1    Falk, R.J.2    Bacon, P.A.3
  • 49
    • 0026505235 scopus 로고
    • Wegener granulomatosis: An analysis of 158 patients
    • Hoffman GS, Kerr GS, Leavitt RY, et al. 1992. Wegener granulomatosis: an analysis of 158 patients. Ann. Intern. Med. 116(6):488-98
    • (1992) Ann. Intern. Med , vol.116 , Issue.6 , pp. 488-498
    • Hoffman, G.S.1    Kerr, G.S.2    Leavitt, R.Y.3
  • 50
    • 0031957478 scopus 로고    scopus 로고
    • Relapse rate, renal survival, and cancer morbidity in patients with Wegener's granulomatosis or microscopic polyangiitis with renal involvement
    • Westman KW, Bygren PG, Olsson H, et al. 1998. Relapse rate, renal survival, and cancer morbidity in patients with Wegener's granulomatosis or microscopic polyangiitis with renal involvement. J. Am. Soc. Nephrol. 9(5):842-52
    • (1998) J. Am. Soc. Nephrol , vol.9 , Issue.5 , pp. 842-852
    • Westman, K.W.1    Bygren, P.G.2    Olsson, H.3
  • 51
    • 0036643850 scopus 로고    scopus 로고
    • Cancer incidence in a population-based cohort of patients with Wegener's granulomatosis
    • DOI 10.1002/ijc.10444
    • Knight A, Askling J, Ekbom A. 2002. Cancer incidence in a population-based cohort of patients with Wegener's granulomatosis. Int. J. Cancer 100(1):82-85 (Pubitemid 34602069)
    • (2002) International Journal of Cancer , vol.100 , Issue.1 , pp. 82-85
    • Knight, A.1    Askling, J.2    Ekbom, A.3
  • 52
    • 38149112725 scopus 로고    scopus 로고
    • Malignancies inWegener's granulomatosis: Incidence and relation to cyclophosphamide therapy in a cohort of 293 patients
    • Faurschou M, Sorensen IJ, Mellemkjaer L, et al. 2008. Malignancies inWegener's granulomatosis: incidence and relation to cyclophosphamide therapy in a cohort of 293 patients. J. Rheumatol. 35(1):100-5
    • (2008) J. Rheumatol , vol.35 , Issue.1 , pp. 100-105
    • Faurschou, M.1    Sorensen, I.J.2    Mellemkjaer, L.3
  • 53
    • 0038122889 scopus 로고    scopus 로고
    • A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies
    • Jayne D, Rasmussen N, Andrassy K, et al. 2003. A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. N. Engl. J. Med. 349(1):36-44
    • (2003) N. Engl. J. Med , vol.349 , Issue.1 , pp. 36-44
    • Jayne, D.1    Rasmussen, N.2    Andrassy, K.3
  • 55
    • 66149168812 scopus 로고    scopus 로고
    • Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: A randomized trial
    • De Groot K, Harper L, Jayne DR, et al. 2009. Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial. Ann. Intern. Med. 150(10):670-80
    • (2009) Ann. Intern. Med , vol.150 , Issue.10 , pp. 670-680
    • De Groot, K.1    Harper, L.2    Jayne, D.R.3
  • 56
    • 77954651554 scopus 로고    scopus 로고
    • Rituximab versus cyclophosphamide for ANCA-associated vasculitis
    • Stone JH, Merkel PA, Spiera R, et al. 2010. Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N. Engl. J. Med. 363(3):221-32
    • (2010) N. Engl. J. Med , vol.363 , Issue.3 , pp. 221-232
    • Stone, J.H.1    Merkel, P.A.2    Spiera, R.3
  • 57
    • 77954632414 scopus 로고    scopus 로고
    • Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis
    • Jones RB, Tervaert JW, Hauser T, et al. 2010. Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis. N. Engl. J. Med. 363(3):211-20
    • (2010) N. Engl. J. Med , vol.363 , Issue.3 , pp. 211-220
    • Jones, R.B.1    Tervaert, J.W.2    Hauser, T.3
  • 58
    • 84869027155 scopus 로고    scopus 로고
    • Brief report: Long-term outcome of a randomized clinical trial comparing methotrexate to cyclophosphamide for remission induction in early systemic antineutrophil cytoplasmic antibody-associated vasculitis
    • Faurschou M, Westman K, Rasmussen N, et al. 2012. Brief report: long-term outcome of a randomized clinical trial comparing methotrexate to cyclophosphamide for remission induction in early systemic antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum. 64(10):3472-77
    • (2012) Arthritis Rheum , vol.64 , Issue.10 , pp. 3472-3477
    • Faurschou, M.1    Westman, K.2    Rasmussen, N.3
  • 59
    • 84860920482 scopus 로고    scopus 로고
    • Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: Long-term follow-up
    • Harper L, Morgan MD, Walsh M, et al. 2012. Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up. Ann. Rheum. Dis. 71(6):955-60
    • (2012) Ann. Rheum. Dis , vol.71 , Issue.6 , pp. 955-960
    • Harper, L.1    Morgan, M.D.2    Walsh, M.3
  • 60
    • 67650094918 scopus 로고    scopus 로고
    • A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis
    • Jones RB, Ferraro AJ, Chaudhry AN, et al. 2009. A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum. 60(7):2156-68
    • (2009) Arthritis Rheum , vol.60 , Issue.7 , pp. 2156-2168
    • Jones, R.B.1    Ferraro, A.J.2    Chaudhry, A.N.3
  • 61
    • 84886240857 scopus 로고    scopus 로고
    • Rituximab versus azathioprine for maintenance in ANCAassociated vasculitis. A prospective study in 117 patients
    • Guillevin L, Pagnoux C, Karras A, et al. 2013. Rituximab versus azathioprine for maintenance in ANCAassociated vasculitis. A prospective study in 117 patients. Presse Med. 424(Pt. 2):679
    • (2013) Presse Med , vol.424 , Issue.PART 2 , pp. 679
    • Guillevin, L.1    Pagnoux, C.2    Karras, A.3
  • 62
    • 78651399830 scopus 로고    scopus 로고
    • Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies
    • Rider LG, Miller FW. 2011. Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies. JAMA 305(2):183-90
    • (2011) JAMA , vol.305 , Issue.2 , pp. 183-190
    • Rider, L.G.1    Miller, F.W.2
  • 63
    • 84873878655 scopus 로고    scopus 로고
    • Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: A randomized, placebo-phase trial
    • Oddis CV, Reed AM, Aggarwal R, et al. 2013. Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: a randomized, placebo-phase trial. Arthritis Rheum. 65(2):314-24
    • (2013) Arthritis Rheum , vol.65 , Issue.2 , pp. 314-324
    • Oddis, C.V.1    Reed, A.M.2    Aggarwal, R.3
  • 64
    • 22544469987 scopus 로고    scopus 로고
    • Sjogren's syndrome
    • Fox RI. 2005. Sjogren's syndrome. Lancet 366(9482):321-31
    • (2005) Lancet , vol.366 , Issue.9482 , pp. 321-331
    • Fox, R.I.1
  • 65
    • 54349116244 scopus 로고    scopus 로고
    • Reduction of fatigue in Sjogren syndrome with rituximab: Results of a randomised, double-blind, placebo-controlled pilot study
    • Dass S, Bowman SJ, Vital EM, et al. 2008. Reduction of fatigue in Sjogren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study. Ann. Rheum. Dis. 67(11):1541-44
    • (2008) Ann. Rheum. Dis , vol.67 , Issue.11 , pp. 1541-1544
    • Dass, S.1    Bowman, S.J.2    Vital, E.M.3
  • 66
    • 77950538947 scopus 로고    scopus 로고
    • Effectiveness of rituximab treatment in primary Sjogren's syndrome: A randomized, double-blind, placebo-controlled trial
    • Meijer JM, Meiners PM, Vissink A, et al. 2010. Effectiveness of rituximab treatment in primary Sj ogren's syndrome: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 62(4):960-68
    • (2010) Arthritis Rheum , vol.62 , Issue.4 , pp. 960-968
    • Meijer, J.M.1    Meiners, P.M.2    Vissink, A.3
  • 67
    • 84873385009 scopus 로고    scopus 로고
    • Tolerance and efficacy of rituximab in primary Sjogren syndrome: Final results of a randomized controlled trial
    • Devauchelle-Pensec V, Mariette X, Jousse-Joulin S, et al. 2012. Tolerance and efficacy of rituximab in primary Sjogren syndrome: final results of a randomized controlled trial. Arthritis Rheum. 64(10, Suppl.):1079
    • (2012) Arthritis Rheum , vol.64 , Issue.10 SUPPL. , pp. 1079
    • Devauchelle-Pensec, V.1    Mariette, X.2    Jousse-Joulin, S.3
  • 68
    • 77949673916 scopus 로고    scopus 로고
    • Longterm safety of patients receiving rituximab in rheumatoid arthritis clinical trials
    • van Vollenhoven RF, Emery P, Bingham CO, et al. 2010. Longterm safety of patients receiving rituximab in rheumatoid arthritis clinical trials. J. Rheumatol. 37(3):558-67
    • (2010) J. Rheumatol , vol.37 , Issue.3 , pp. 558-567
    • Van Vollenhoven, R.F.1    Emery, P.2    Bingham, C.O.3
  • 69
    • 77956391149 scopus 로고    scopus 로고
    • Risk factors for severe infections in patients with rheumatoid arthritis treated with rituximab in the autoimmunity and rituximab registry
    • Gottenberg JE, Ravaud P, Bardin T, et al. 2010. Risk factors for severe infections in patients with rheumatoid arthritis treated with rituximab in the autoimmunity and rituximab registry. Arthritis Rheum. 62(9):2625-32
    • (2010) Arthritis Rheum , vol.62 , Issue.9 , pp. 2625-2632
    • Gottenberg, J.E.1    Ravaud, P.2    Bardin, T.3
  • 70
    • 77955379986 scopus 로고    scopus 로고
    • Safety and efficacy of rituximab in systemic lupus erythematosus: Results from 136 patients from the French AutoImmunity and Rituximab registry
    • Terrier B, Amoura Z, Ravaud P, et al. 2010. Safety and efficacy of rituximab in systemic lupus erythematosus: results from 136 patients from the French AutoImmunity and Rituximab registry. Arthritis Rheum. 62(8):2458-66
    • (2010) Arthritis Rheum , vol.62 , Issue.8 , pp. 2458-2466
    • Terrier, B.1    Amoura, Z.2    Ravaud, P.3
  • 71
    • 80052777262 scopus 로고    scopus 로고
    • Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis
    • Clifford DB, Ances B, Costello C, et al. 2011. Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis. Arch. Neurol. 68(9):1156-64
    • (2011) Arch. Neurol , vol.68 , Issue.9 , pp. 1156-1164
    • Clifford, D.B.1    Ances, B.2    Costello, C.3
  • 72
    • 73249116052 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy: A national estimate of frequency in systemic lupus erythematosus and other rheumatic diseases
    • Molloy ES, Calabrese LH. 2009. Progressive multifocal leukoencephalopathy: a national estimate of frequency in systemic lupus erythematosus and other rheumatic diseases. Arthritis Rheum. 60(12):3761- 65
    • (2009) Arthritis Rheum , vol.60 , Issue.12 , pp. 3761-3765
    • Molloy, E.S.1    Calabrese, L.H.2
  • 73
    • 84869072981 scopus 로고    scopus 로고
    • Long-term safety profile of belimumab plus standard therapy in patients with systemic lupus erythematosus
    • Merrill JT, Ginzler EM, Wallace DJ, et al. 2012. Long-term safety profile of belimumab plus standard therapy in patients with systemic lupus erythematosus. Arthritis Rheum. 64(10):3364-73
    • (2012) Arthritis Rheum , vol.64 , Issue.10 , pp. 3364-3373
    • Merrill, J.T.1    Ginzler, E.M.2    Wallace, D.J.3


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