Induction of human plasmablasts during infection with antibiotic-resistant nosocomial bacteria

Journal of Antimicrobial Chemotherapy

Volumn 69, Issue 7, 2014, Pages 1830-1833

  Band, Victor I ^a,b   Ibegbu, Chris ^b   Kaur, Surinder Pal ^b   Cagle, Stephanie M ^a,c   Trible, Ronald ^a   Jones, Crystal L ^a,b   Wang, Yun F ^a,c   Kraft, Colleen S ^a   Ray, Susan M ^a,c   Wrammert, Jens ^b   Weiss, David S ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c GRADY MEMORIAL HOSPITAL   (United States)

Author keywords

Acinetobacter baumannii; Antibody therapy; Nosocomial infections

Indexed keywords

ANTIBIOTIC AGENT;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BLOOD CELL COUNT; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PATHOGENESIS; PLASMA CELL; PLASMABLAST; ADULT; AGED; CROSS INFECTION; DRUG EFFECTS; FEMALE; IMMUNOLOGY; ISOLATION AND PURIFICATION; LYMPHOCYTE ACTIVATION; MALE; MICROBIOLOGY; MIDDLE AGED;

ACINETOBACTER BAUMANNII; ADULT; AGED; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; FEMALE; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PLASMA CELLS;

EID: 84900494371     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku047     Document Type: Article

References (11)

1. Reed D, Kemmerly SA. Infection control and prevention: a review of hospital-acquired infections and the economic implications. Ochsner J 2009; 9: 27-31.
2. Rice LB. Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE. J Infect Dis 2008; 197: 1079-81.
3. Magiorakos AP, Srinivasan A, Carey RB et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012; 18: 268-81.
4. White AR. Effective antibacterials: at what cost? The economics of antibacterial resistance and its control. J Antimicrob Chemother 2011; 66: 1948-53.
5. Wrammert J, Smith K, Miller J et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature 2008; 453: 667-71.
6. Wrammert J, Onlamoon N, Akondy RS et al. Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. J Virol 2012; 86: 2911-8.
7. Radbruch A, Muehlinghaus G, Luger EO et al. Competence and competition: the challenge of becoming a long-lived plasma cell. Nat Rev Immunol 2006; 6: 741-50.
8. McConnell MJ, Dominguez-Herrera J, Smani Y et al. Vaccination with outer membrane complexes elicits rapid protective immunity to multidrug-resistant Acinetobacter baumannii. Infect Immun 2011; 79: 518-26.
9. Russo TA, Beanan JM, Olson R et al. The K1 capsular polysaccharide from Acinetobacter baumannii is a potential therapeutic target via passive immunization. Infect Immun 2013; 81: 915-22.
10. Luo G, Lin L, Ibrahim AS et al. Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection. PLoS One 2012; 7: e29446.
11. Presta LG. Engineering of therapeutic antibodies to minimize immunogenicity and optimize function. Adv Drug Deliv Rev 2006; 58: 640-56.