Genetic variants may play an important role in mRNA-miRNA interaction: Evidence for haplotype-dependent downregulation of ABCC2 (MRP2) by miRNA-379

Pharmacogenetics and Genomics

Volumn 24, Issue 6, 2014, Pages 283-291

  Werk, Anneke N ^a   Bruckmueller, Henrike ^a   Haenisch, Sierk ^a   Cascorbi, Ingolf ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

30 UTR; ABC transporter; ABCC2 haplotype; miRNA; pharmacogenomics

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; MICRORNA; MIRNA 379; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; UNCLASSIFIED DRUG; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2;

3' UNTRANSLATED REGION; ADULT; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; RNA STABILITY;

ADULT; FEMALE; GENE EXPRESSION REGULATION; HAPLOTYPES; HUMANS; MICRORNAS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA STABILITY; RNA, MESSENGER;

EID: 84900489961     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0000000000000046     Document Type: Article

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