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Volumn 40, Issue 5, 2014, Pages 199-210

Effect of nilotinib on airway remodeling in a murine model of chronic asthma

Author keywords

Airway remodeling; Asthma; Nilotinib; Platelet derived growth factor receptor; Proto oncogene protein c Kit; Smooth muscle

Indexed keywords

HYDROXYPROLINE; IMATINIB; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUCIN 5AC; NILOTINIB; OVALBUMIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; STEM CELL FACTOR; 4-METHYL-N-(3-(4-METHYLIMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)PHENYL)-3-((4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO)BENZAMIDE; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; MUC5AC PROTEIN, MOUSE; PYRIMIDINE DERIVATIVE; STEM CELL FACTOR RECEPTOR;

EID: 84900456685     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.3109/01902148.2013.831959     Document Type: Article
Times cited : (15)

References (27)
  • 1
    • 38049121369 scopus 로고    scopus 로고
    • Airway modeling and remodeling in the pathogenesis of asthma
    • Warner SM, Knight DA: Airway modeling and remodeling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol. 2008;8:44-48.
    • (2008) Curr Opin Allergy Clin Immunol. , vol.8 , pp. 44-48
    • Warner, S.M.1    Knight, D.A.2
  • 3
    • 21844436050 scopus 로고    scopus 로고
    • Remodelling of airway smooth muscle in asthma: What sort do you have
    • James A: Remodelling of airway smooth muscle in asthma: What sort do you have Clin Exp Allergy. 2005;35:703-707.
    • (2005) Clin Exp Allergy. , vol.35 , pp. 703-707
    • James, A.1
  • 4
    • 29144464371 scopus 로고    scopus 로고
    • Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the t reatment of chronic myeloid leukaemia
    • Manley PW, Cowan-Jacob SW, Mestan J: Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the t reatment of chronic myeloid leukaemia. Biochim Biophys Acta. 2005;1754:3-13.
    • (2005) Biochim Biophys Acta. , vol.1754 , pp. 3-13
    • Manley, P.W.1    Cowan-Jacob, S.W.2    Mestan, J.3
  • 7
    • 0642304831 scopus 로고    scopus 로고
    • Stem cell factor: A hemopoietic cytokine with important targets in asthma
    • Oliveira SH, Lukacs NW: Stem cell factor: A hemopoietic cytokine with important targets in asthma. Curr Drug Targets Inflamm Allergy. 2003;2:313-318.
    • (2003) Curr Drug Targets Inflamm Allergy. , vol.2 , pp. 313-318
    • Oliveira, S.H.1    Lukacs, N.W.2
  • 8
    • 33644752698 scopus 로고    scopus 로고
    • Stem cell factor and its receptor c-Kit as targets for inflammatory diseases
    • Reber L, Da Silva CA, Frossard N: Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eur J Pharmacol. 2006;533:327-340.
    • (2006) Eur J Pharmacol. , vol.533 , pp. 327-340
    • Reber, L.1    Da Silva, C.A.2    Frossard, N.3
  • 9
    • 33744783176 scopus 로고    scopus 로고
    • Egf and pdgf receptor tyrosine kinases as therapeutic targets for chronic lung diseases
    • Ingram JL, Bon ner JC: EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases. Curr Mol Med. 2006;6:409-421.
    • (2006) Curr Mol Med. , vol.6 , pp. 409-421
    • Ingram, J.L.1    Bonner, J.C.2
  • 10
    • 30744464627 scopus 로고    scopus 로고
    • Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity
    • Chung KF, Hew M, Score J, Jones AV, Reiter A, Cross NC, Bain BJ: Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity. Eur Respir J. 2006;27:230-232.
    • (2006) Eur Respir J. , vol.27 , pp. 230-232
    • Chung, K.F.1    Hew, M.2    Score, J.3    Jones, A.V.4    Reiter, A.5    Cross, N.C.6    Bain, B.J.7
  • 11
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25:402-408.
    • (2001) Methods. , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 17
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis RJ: The mitogen-activated protein kinase signal transduction pathway. J Biol Chem. 1993;268:14553-14556.
    • (1993) J Biol Chem. , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 18
    • 25144481536 scopus 로고    scopus 로고
    • Taurine suppresses platelet-derived growth factor (pdgf) bb-induced pdgf-beta receptor phosphorylation by protein tyrosine phosphatase-mediated dephosphorylation in vascular smooth muscle cells
    • Yoshimura H, Nariai Y, Terashim a M, Mitani T, Tanigawa Y: Taurine suppresses platelet-derived growth factor (PDGF) BB-induced PDGF-beta receptor phosphorylation by protein tyrosine phosphatase-mediated dephosphorylation in vascular smooth muscle cells. Biochim Biophys Acta. 2005;1745:350-360.
    • (2005) Biochim Biophys Acta. , vol.1745 , pp. 350-360
    • Yoshimura, H.1    Nariai, Y.2    Terashim, A.M.3    Mitani, T.4    Tanigawa, Y.5
  • 19
    • 18844470009 scopus 로고    scopus 로고
    • Role of E2F and ERK1/2 in STI571-mediated smooth muscle cell growth arrest and cyclin A transcriptional repression
    • Sanz-Gonzalez SM, Castro C, Perez P, Andres V: Role of E2F and ERK1/2 in STI571-mediated smooth muscle cell growth arrest and cyclin A transcriptional repression. Bi ochem Biophys Res Commun. 2004;317:972-979.
    • (2004) Bi Ochem Biophys Res Commun. , vol.317 , pp. 972-979
    • Sanz-Gonzalez, S.M.1    Castro, C.2    Perez, P.3    Andres, V.4
  • 22
    • 80052267387 scopus 로고    scopus 로고
    • What effect does asthma treatment have on airway remodeling Current perspectives
    • quiz 449-450
    • Durrani SR, Viswanathan RK, Busse WW: What effect does asthma treatment have on airway remodeling Current perspectives. J Allergy Clin Immunol. 2011;128:439-448; quiz 449-450.
    • (2011) J Allergy Clin Immunol. , vol.128 , pp. 439-448
    • Durrani, S.R.1    Viswanathan, R.K.2    Busse, W.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.