-
1
-
-
38049121369
-
Airway modeling and remodeling in the pathogenesis of asthma
-
Warner SM, Knight DA: Airway modeling and remodeling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol. 2008;8:44-48.
-
(2008)
Curr Opin Allergy Clin Immunol.
, vol.8
, pp. 44-48
-
-
Warner, S.M.1
Knight, D.A.2
-
3
-
-
21844436050
-
Remodelling of airway smooth muscle in asthma: What sort do you have
-
James A: Remodelling of airway smooth muscle in asthma: What sort do you have Clin Exp Allergy. 2005;35:703-707.
-
(2005)
Clin Exp Allergy.
, vol.35
, pp. 703-707
-
-
James, A.1
-
4
-
-
29144464371
-
Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the t reatment of chronic myeloid leukaemia
-
Manley PW, Cowan-Jacob SW, Mestan J: Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the t reatment of chronic myeloid leukaemia. Biochim Biophys Acta. 2005;1754:3-13.
-
(2005)
Biochim Biophys Acta.
, vol.1754
, pp. 3-13
-
-
Manley, P.W.1
Cowan-Jacob, S.W.2
Mestan, J.3
-
5
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Lobo C, Pasquini R, Clark RE, Hochhaus A, Hughes TP, Gallagher N, Hoenekopp A, Dong M, Haque A, Larson RA, Kantarjian HM: Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med. 2010;362:2251-2259.
-
(2010)
N Engl J Med.
, vol.362
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
Le Coutre, P.4
Etienne, G.5
Lobo, C.6
Pasquini, R.7
Clark, R.E.8
Hochhaus, A.9
Hughes, T.P.10
Gallagher, N.11
Hoenekopp, A.12
Dong, M.13
Haque, A.14
Larson, R.A.15
Kantarjian, H.M.16
-
6
-
-
79551543897
-
Effect of imatinib on airway smooth muscle thickening in a murine model of chronic asthma
-
Rhee CK, Kim JW, Park CK, Kim JS, Kang JY, Kim SJ, Kim SC, Kwon SS, Kim YK, Park SH, Lee SY: Effect of imatinib on airway smooth muscle thickening in a murine model of chronic asthma. Int Arch Allergy Immunol. 2011;155:243-251.
-
(2011)
Int Arch Allergy Immunol.
, vol.155
, pp. 243-251
-
-
Rhee, C.K.1
Kim, J.W.2
Park, C.K.3
Kim, J.S.4
Kang, J.Y.5
Kim, S.J.6
Kim, S.C.7
Kwon, S.S.8
Kim, Y.K.9
Park, S.H.10
Lee, S.Y.11
-
7
-
-
0642304831
-
Stem cell factor: A hemopoietic cytokine with important targets in asthma
-
Oliveira SH, Lukacs NW: Stem cell factor: A hemopoietic cytokine with important targets in asthma. Curr Drug Targets Inflamm Allergy. 2003;2:313-318.
-
(2003)
Curr Drug Targets Inflamm Allergy.
, vol.2
, pp. 313-318
-
-
Oliveira, S.H.1
Lukacs, N.W.2
-
8
-
-
33644752698
-
Stem cell factor and its receptor c-Kit as targets for inflammatory diseases
-
Reber L, Da Silva CA, Frossard N: Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eur J Pharmacol. 2006;533:327-340.
-
(2006)
Eur J Pharmacol.
, vol.533
, pp. 327-340
-
-
Reber, L.1
Da Silva, C.A.2
Frossard, N.3
-
9
-
-
33744783176
-
Egf and pdgf receptor tyrosine kinases as therapeutic targets for chronic lung diseases
-
Ingram JL, Bon ner JC: EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases. Curr Mol Med. 2006;6:409-421.
-
(2006)
Curr Mol Med.
, vol.6
, pp. 409-421
-
-
Ingram, J.L.1
Bonner, J.C.2
-
10
-
-
30744464627
-
Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity
-
Chung KF, Hew M, Score J, Jones AV, Reiter A, Cross NC, Bain BJ: Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity. Eur Respir J. 2006;27:230-232.
-
(2006)
Eur Respir J.
, vol.27
, pp. 230-232
-
-
Chung, K.F.1
Hew, M.2
Score, J.3
Jones, A.V.4
Reiter, A.5
Cross, N.C.6
Bain, B.J.7
-
11
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25:402-408.
-
(2001)
Methods.
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
12
-
-
0033001251
-
Human bronchial smooth muscle cells in culture produce stem cell factor
-
Kassel O, Schmidlin F, Duvernelle C, Gasser B, Massard G, Frossard N: Human bronchial smooth muscle cells in culture produce stem cell factor. Eur Respir J. 1999;13:951-954.
-
(1999)
Eur Respir J.
, vol.13
, pp. 951-954
-
-
Kassel, O.1
Schmidlin, F.2
Duvernelle, C.3
Gasser, B.4
Massard, G.5
Frossard, N.6
-
13
-
-
18144389027
-
Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact
-
Thangam EB, Venkatesha RT, Zaidi AK, Jordan-Sciutto KL, Goncharov DA, Krymskaya VP, Amrani Y, Panettieri RA, Jr., Ali H: Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact. FASEB J. 2005;19:798-800.
-
(2005)
FASEB J.
, vol.19
, pp. 798-800
-
-
Thangam, E.B.1
Venkatesha, R.T.2
Zaidi, A.K.3
Jordan-Sciutto, K.L.4
Goncharov, D.A.5
Krymskaya, V.P.6
Amrani, Y.7
Panettieri Jr., R.A.8
Ali, H.9
-
14
-
-
0037303378
-
PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression
-
Yu Y, Sweeney M, Zhang S, Platoshyn O, Landsberg J, Rothman A, Yuan JX: PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression. Am J Physiol Cell Physiol. 2003;284:C316-C330.
-
(2003)
Am J Physiol Cell Physiol.
, vol.284
-
-
Yu, Y.1
Sweeney, M.2
Zhang, S.3
Platoshyn, O.4
Landsberg, J.5
Rothman, A.6
Yuan, J.X.7
-
15
-
-
26444540768
-
Reversal of experimental pulmonary hypertension by PDGF inhibition
-
Schermuly RT, Dony E, Ghofrani HA, Pullamsetti S, Savai R, Roth M, Sydykov A, Lai YJ, Weissmann N, Seeger W, Grimminger F: Reversal of experimental pulmonary hypertension by PDGF inhibition. J Clin Invest. 2005;115:2811-2821.
-
(2005)
J Clin Invest.
, vol.115
, pp. 2811-2821
-
-
Schermuly, R.T.1
Dony, E.2
Ghofrani, H.A.3
Pullamsetti, S.4
Savai, R.5
Roth, M.6
Sydykov, A.7
Lai, Y.J.8
Weissmann, N.9
Seeger, W.10
Grimminger, F.11
-
16
-
-
46349109892
-
Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension
-
Perros F, Montani D, Dorfmuller P, Durand-Gasselin I, Tcherakian C, Le Pavec J, Mazmanian M, Fadel E , Mussot S, MercierO, Herve P, EmilieD, Eddahibi S, Simonneau G, Souza R, Humbert M: Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 200 8;178:81-88.
-
(2008)
Am J Respir Crit Care Med.
, vol.178
, pp. 81-88
-
-
Perros, F.1
Montani, D.2
Dorfmuller, P.3
Durand-Gasselin, I.4
Tcherakian, C.5
Le Pavec, J.6
Mazmanian, M.7
Fadel, E.8
Mussot, S.9
Mercier, O.10
Herve, P.11
Emilie, D.12
Eddahibi, S.13
Simonneau, G.14
Souza, R.15
Humbert, M.16
-
17
-
-
0027165150
-
The mitogen-activated protein kinase signal transduction pathway
-
Davis RJ: The mitogen-activated protein kinase signal transduction pathway. J Biol Chem. 1993;268:14553-14556.
-
(1993)
J Biol Chem.
, vol.268
, pp. 14553-14556
-
-
Davis, R.J.1
-
18
-
-
25144481536
-
Taurine suppresses platelet-derived growth factor (pdgf) bb-induced pdgf-beta receptor phosphorylation by protein tyrosine phosphatase-mediated dephosphorylation in vascular smooth muscle cells
-
Yoshimura H, Nariai Y, Terashim a M, Mitani T, Tanigawa Y: Taurine suppresses platelet-derived growth factor (PDGF) BB-induced PDGF-beta receptor phosphorylation by protein tyrosine phosphatase-mediated dephosphorylation in vascular smooth muscle cells. Biochim Biophys Acta. 2005;1745:350-360.
-
(2005)
Biochim Biophys Acta.
, vol.1745
, pp. 350-360
-
-
Yoshimura, H.1
Nariai, Y.2
Terashim, A.M.3
Mitani, T.4
Tanigawa, Y.5
-
19
-
-
18844470009
-
Role of E2F and ERK1/2 in STI571-mediated smooth muscle cell growth arrest and cyclin A transcriptional repression
-
Sanz-Gonzalez SM, Castro C, Perez P, Andres V: Role of E2F and ERK1/2 in STI571-mediated smooth muscle cell growth arrest and cyclin A transcriptional repression. Bi ochem Biophys Res Commun. 2004;317:972-979.
-
(2004)
Bi Ochem Biophys Res Commun.
, vol.317
, pp. 972-979
-
-
Sanz-Gonzalez, S.M.1
Castro, C.2
Perez, P.3
Andres, V.4
-
20
-
-
80051786966
-
Effect of nilotinib on bleomycin-induced acu te lung injury and pulmonary fibrosis in mice
-
Rhee CK, Lee SH, Yoon HK, Kim SC, Lee SY, Kwon SS, Kim YK, Kim KH, Kim TJ, Kim JW: Effect of nilotinib on bleomycin-induced acu te lung injury and pulmonary fibrosis in mice. Respiration. 2011;82:273-287.
-
(2011)
Respiration.
, vol.82
, pp. 273-287
-
-
Rhee, C.K.1
Lee, S.H.2
Yoon, H.K.3
Kim, S.C.4
Lee, S.Y.5
Kwon, S.S.6
Kim, Y.K.7
Kim, K.H.8
Kim, T.J.9
Kim, J.W.10
-
21
-
-
84861530248
-
Role of Src tyrosine kinases in experimental pulmonary hypertension
-
Pullamsetti SS Berghausen EM Dabral S Tretyn A Butrous E Savai R Butrous G Dahal BK Brand es RP Ghofrani HA Weissmann N Grimminger F Seeger W Rosenkranz S Schermuly RT Role of Src tyrosine kinases in experimental pulmonary hypertension. Arterioscler Thromb Vasc Biol. 2012 32 1354-1365.
-
(2012)
Arterioscler Thromb Vasc Biol.
, vol.32
, pp. 1354-1365
-
-
Pullamsetti, S.S.1
Berghausen, E.M.2
Dabral, S.3
Tretyn, A.4
Butrous, E.5
Savai, R.6
Butrous, G.7
Dahal, B.K.8
Brandes, R.P.9
Ghofrani, H.A.10
Weissmann, N.11
Grimminger, F.12
Seeger, W.13
Rosenkranz, S.14
Schermuly, R.T.15
-
22
-
-
80052267387
-
What effect does asthma treatment have on airway remodeling Current perspectives
-
quiz 449-450
-
Durrani SR, Viswanathan RK, Busse WW: What effect does asthma treatment have on airway remodeling Current perspectives. J Allergy Clin Immunol. 2011;128:439-448; quiz 449-450.
-
(2011)
J Allergy Clin Immunol.
, vol.128
, pp. 439-448
-
-
Durrani, S.R.1
Viswanathan, R.K.2
Busse, W.W.3
-
24
-
-
80052383499
-
Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chron ic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial
-
Kantarjian HM, Hochhaus A, Saglio G, De Souza C, Flinn IW, Stenke L, Goh YT, Rosti G, Nakamae H, Gallagher NJ, Hoenekopp A, Blakesley RE, Larson RA, Hughes TP: Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chron ic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial. Lancet Oncol. 2011;12:841-851.
-
(2011)
Lancet Oncol.
, vol.12
, pp. 841-851
-
-
Kantarjian, H.M.1
Hochhaus, A.2
Saglio, G.3
De Souza, C.4
Flinn, I.W.5
Stenke, L.6
Goh, Y.T.7
Rosti, G.8
Nakamae, H.9
Gallagher, N.J.10
Hoenekopp, A.11
Blakesley, R.E.12
Larson, R.A.13
Hughes, T.P.14
-
25
-
-
38449123884
-
Penh is not a measure of airway resistance!
-
Lundblad LK, Irvin CG, Hantos Z, Sly P, Mitzner W, Bates JH: Penh is not a measure of airway resistance! Eur Respir J. 2007;30:805.
-
(2007)
Eur Respir J.
, vol.30
, pp. 805
-
-
Lundblad, L.K.1
Irvin, C.G.2
Hantos, Z.3
Sly, P.4
Mitzner, W.5
Bates, J.H.6
-
27
-
-
4444368190
-
The use and misuse of Penh in animal models of lung disease
-
Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, Eidelman D, Ludwig M, Macklem P, Martin J, Milic-Emili J, Hantos Z, Hyatt R, Lai-Fook S, Leff A, Solway J, Lutchen K, Suki B, Mitzner W, Pare P, Pride N, Sly P: The use and misuse of Penh in animal models of lung disease. Am J Respir CellMol Biol. 2004;31:373-374.
-
(2004)
Am J Respir CellMol Biol.
, vol.31
, pp. 373-374
-
-
Bates, J.1
Irvin, C.2
Brusasco, V.3
Drazen, J.4
Fredberg, J.5
Loring, S.6
Eidelman, D.7
Ludwig, M.8
Macklem, P.9
Martin, J.10
Milic-Emili, J.11
Hantos, Z.12
Hyatt, R.13
Lai-Fook, S.14
Leff, A.15
Solway, J.16
Lutchen, K.17
Suki, B.18
Mitzner, W.19
Pare, P.20
Pride, N.21
Sly, P.22
more..
|