Protective effect of melatonin on adriamycin-induced cardiotoxicity in rats

Turk Kardiyoloji Dernegi Arsivi

Volumn 42, Issue 3, 2014, Pages 265-273

  Bilginoǧlu, Ayça ^a   Aydin, Duygu ^b   Özsoy, Şeyma ^c   Aygün, Hatice ^c  

^a YILDIRIM BEYAZIT UNIVERSITY   (Turkey)

^b TURGUT OZAL UNIVERSITY   (Turkey)

^c GAZIOSMANPASA UNIVERSITY   (Turkey)

Author keywords

Adriamycin; Antioxidants; Cardiovascular diseases prevention control; Coronary disease; Disease models, animal; Melatonin; Rats, wistar.

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CREATINE KINASE MB; DOXORUBICIN; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; MELATONIN; OXILIFE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTIOXIDANT; CREATINE KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ECG ABNORMALITY; ELECTROCARDIOGRAPHY; ENZYME BLOOD LEVEL; EXPERIMENTAL CARDIOVASCULAR DISEASE; EXPERIMENTAL STUDY; GRAVIMETRY; HEART PROTECTION; HEART RATE; HORMONAL THERAPY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; P WAVE; QRS COMPLEX; QT INTERVAL; RANDOMIZATION; RAT; RR INTERVAL; ST SEGMENT; ST SEGMENT ELEVATION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; DRUG EFFECTS; HEART; WISTAR RAT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; BIOCHEMICAL ANALYSIS; ENZYME ACTIVITY; LIPID ANALYSIS; OUTCOME ASSESSMENT; R WAVE AMPLITUDE;

ANIMALS; ANTIOXIDANTS; CARDIOTOXICITY; DOXORUBICIN; ELECTROCARDIOGRAPHY; HEART; LIPID PEROXIDATION; MALE; MELATONIN; RATS; RATS, WISTAR;

EID: 84900455886     PISSN: 10165169     EISSN: None     Source Type: Journal    
DOI: 10.5543/tkda.2014.36089     Document Type: Article

References (28)

1. Lefrak EA, Pitha J, Rosenheim S, Gottlieb JA. A clinicopathologic analysis of adriamycin cardiotoxicity. Cancer 1973;32:302-14. CrossRef
2. Bristow MR, Billingham ME, Mason JW, Daniels JR. Clinical spectrum of anthracycline antibiotic cardiotoxicity. Cancer Treat Rep 1978;62:873-9. (Pubitemid 8377881)
3. Simůnek T, Stérba M, Popelová O, Adamcová M, Hrdina R, Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol Rep 2009;61:154-71. CrossRef
4. Acikel M, Buyukokuroglu ME, Aksoy H, Erdogan F, Erol MK. Protective effects of melatonin against myocardial injury induced by isoproterenol in rats. J Pineal Res 2003;35:75-9. (Pubitemid 36960344)
5. Kaneko S, Okumura K, Numaguchi Y, Matsui H, Murase K, Mokuno S, et al. Melatonin scavenges hydroxyl radical and protects isolated rat hearts from ischemic reperfusion injury. Life Sci 2000;67:101-12. CrossRef (Pubitemid 30414477)
6. Liu X, Chen Z, Chua CC, Ma YS, Youngberg GA, Hamdy R, et al. Melatonin as an effective protector against doxorubicin-induced cardiotoxicity. Am J Physiol Heart Circ Physiol 2002;283:H254-63. (Pubitemid 34705347)
7. Robert J. Preclinical assessment of anthracycline cardiotoxicity in laboratory animals: predictiveness and pitfalls. Cell Biol Toxicol 2007;23:27-37. CrossRef (Pubitemid 44950186)
8. Patel V, Upaganlawar A, Zalawadia R, Balaraman R. Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: A biochemical, electrocardiographic and histoarchitectural evaluation. Eur J Pharmacol 2010;644:160-8. CrossRef
9. Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988;34:497-500.
10. Wasowicz W, Nève J, Peretz A. Optimized steps in fluorometric determination of thiobarbituric acid-reactive substances in serum: importance of extraction pH and influence of sample preservation and storage. Clin Chem 1993;39:2522-6. (Pubitemid 24008241)
11. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-69.
12. Cooper DK. Electrocardiographic studies in the rat in physiological and pathological states. Cardiovasc Res 1969;3:419-25. CrossRef
13. Iarussi D, Indolfi P, Casale F, Coppolino P, Tedesco MA, Di Tullio MT. Recent advances in the prevention of anthracycline cardiotoxicity in childhood. Curr Med Chem 2001;8:1649-60. (Pubitemid 33076806)
14. Neilan TG, Blake SL, Ichinose F, Raher MJ, Buys ES, Jassal DS, et al. Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin. Circulation 2007;116:506-14. CrossRef (Pubitemid 47450259)
15. Wallace KB. Doxorubicin-induced cardiac mitochondrionopathy. Pharmacol Toxicol 2003;93:105-15. CrossRef (Pubitemid 37108538)
16. Holland RP, Brooks H, Lidl B. Spatial and nonspatial influences on the TG-ST segment deflection of ischemia. Theoretical and experimental analysis in the pig. J Clin Invest 1977;60:197-214. CrossRef (Pubitemid 8145158)
17. Boucek RJ Jr, Dodd DA, Atkinson JB, Oquist N, Olson RD. Contractile failure in chronic doxorubicin-induced cardiomyopathy. J Mol Cell Cardiol 1997;29:2631-40. CrossRef (Pubitemid 27466486)
18. Hazari MS, Haykal-Coates N, Winsett DW, Costa DL, Farraj AK. Continuous electrocardiogram reveals differences in the short-term cardiotoxic response of Wistar-Kyoto and spontaneously hypertensive rats to doxorubicin. Toxicol Sci 2009;110:224-34. CrossRef
19. Fisher PW, Salloum F, Das A, Hyder H, Kukreja RC. Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity. Circulation 2005;111:1601-10. CrossRef (Pubitemid 40525159)
20. Venkatesan N. Curcumin attenuation of acute adriamycin myocardial toxicity in rats. Br J Pharmacol 1998;124:425-7. (Pubitemid 28254494)
21. Pacher P, Liaudet L, Bai P, Virag L, Mabley JG, Haskó G, et al. Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. J Pharmacol Exp Ther 2002;300:862-7. CrossRef (Pubitemid 34164989)
22. Saad SY, Najjar TA, Al-Rikabi AC. The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats. Pharmacol Res 2001;43:211-8. (Pubitemid 32601427)
23. Ozdoǧan K, Taşkin E, Dursun N. Protective effect of carnosine on adriamycin-induced oxidative heart damage in rats. Anadolu Kardiyol Derg 2011;11:3-10. CrossRef
24. Narin F, Demir F, Akgün H, Baykan A, Üzüm K, Kuzugüden S. Doxorubucin-induced experimental cardiotoxicity and effect of pentoxyphylline on cardiotoxicity. Türk Kardiyol Dern Arş 2004;32:279-87. (Pubitemid 351309207)
25. Halliwell B. Reactive oxygen species in living systems: source, biochemistry, and role in human disease. Am J Med 1991;91:14-22. CrossRef
26. Li T, Danelisen I, Belló-Klein A, Singal PK. Effects of probucol on changes of antioxidant enzymes in adriamycin-induced cardiomyopathy in rats. Cardiovasc Res 2000;46:523-30. CrossRef (Pubitemid 30319337)
27. Mukherjee S, Banerjee SK, Maulik M, Dinda AK, Talwar KK, Maulik SK. Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-alpha expression. BMC Pharmacol 2003;3:16. CrossRef
28. Iliskovic N, Singal PK. Lipid lowering: an important factor in preventing adriamycin-induced heart failure. Am J Pathol 1997;150:727-34. (Pubitemid 27073799)