Tumor necrosis factor inhibitor therapy but not standard therapy is associated with resolution of erosion in the sacroiliac joints of patients with axial spondyloarthritis

Arthritis Research and Therapy

Volumn 16, Issue 2, 2014, Pages

  Pedersen, Susanne J ^a   Wichuk, Stephanie ^b   Chiowchanwisawakit, Praveena ^c   Lambert, Robert G ^b   Maksymowych, Walter P ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF ALBERTA   (Canada)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA INHIBITOR; ANTIRHEUMATIC AGENT; TUMOR NECROSIS FACTOR;

ADULT; ANKYLOSING SPONDYLITIS; ARTICLE; BONE EROSION; BONE LESION; CARTILAGE; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DISEASE SEVERITY; FEMALE; HUMAN; LIGAMENT; MAJOR CLINICAL STUDY; MALE; METAPLASIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PROSPECTIVE STUDY; SACROILIAC JOINT; SACROILIAC JOINT STRUCTURAL SCORE; SCORING SYSTEM; SPONDYLARTHRITIS; STANDARD; TISSUE SLICE; ANTAGONISTS AND INHIBITORS; MIDDLE AGED; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ADULT; ANTIRHEUMATIC AGENTS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; SACROILIAC JOINT; SEVERITY OF ILLNESS INDEX; SPONDYLARTHRITIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84900446833     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4548     Document Type: Article

References (17)

1. Chiowchanwisawakit P, Lambert RGW, Conner-Spady B, Maksymowych WP. Focal fat lesions at vertebral corners on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis. Arthritis Rheum 2011, 63:2215-2225. 10.1002/art.30393, 21484769.
2. Maksymowych WP, Morency N, Conner-Spady B, Lambert RG. Suppression of inflammation and effects on new bone formation in ankylosing spondylitis: evidence for a window of opportunity in disease modification. Ann Rheum Dis 2013, 72:23-28. 10.1136/annrheumdis-2011-200859, 22562977.
3. Song I-H, Hermann KG, Haibel H, Althoff CE, Poddubnyy D, Listing J, Weiss A, Freundlich B, Rudwaleit M, Sieper J. Relationship between active inflammatory lesions in the spine and sacroiliac joints and new development of chronic lesions on whole-body MRI in early axial spondyloarthritis: results of the ESTHER trial at week 48. Ann Rheum Dis 2011, 70:1257-1263. 10.1136/ard.2010.147033, 3103667, 21551507.
4. østergaard M, Maksymowych WP, Pedersen SJ, Chiowchanwisawakit P, Lambert RGW. Structural lesions detected by magnetic resonance imaging in the spine of patients with spondyloarthritis - definitions, assessment system, and reference image set. J Rheumatol 2009, 36:18-34.
5. Weber U, Pedersen SJ, Ostergaard M, Rufibach K, Lambert R, Maksymowych WP. Can erosions on MRI of the sacroiliac joints be reliably detected in patients with ankylosing spondylitis? A cross-sectional study. Arthritis Res Ther 2012, 14:R124. 10.1186/ar3854, 3446505, 22626458.
6. Maksymowych WP, Wichuk S, Chiowchanwasawakit P, Lambert RG, Pedersen S. The spondylo arthritis research consortium of Canada MRI sacroiliac joint structural score: a method for reliable detection of structural progression. Arthritis Rheum 2013, 65:S1239.
7. van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984, 27:361-368. 10.1002/art.1780270401, 6231933.
8. Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, Dougados M, Hermann K-G, Landewé R, Maksymowych W, van der Heijde D. The assessment of spondyloarthritis international society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis 2009, 68:ii1-ii44.
9. Maksymowych WP, Inman RD, Salonen D, Dhillon SS, Williams M, Stone M, Conner-Spady B, Palsat J, Lambert RG. Spondyloarthritis research consortium of Canada magnetic resonance imaging index for assessment of sacroiliac joint inflammation in ankylosing spondylitis. Arthritis Rheum 2005, 53:703-709. 10.1002/art.21445, 16208659.
10. Gladman DD, Rahman P, Cook RJ, Shen H, Zummer M, Thomson G, Nair B, Rohekar S, Ayearst R, Inman RD, Maksymowych W. The spondyloarthritis research consortium of Canada registry for spondyloarthritis. J Rheumatol 2011, 38:1343-1348. 10.3899/jrheum.101102, 21498484.
11. The Spondyloarthritis Research Consortium of Canada MRI Sacroiliac Joint Structural Score (SSS) online training module: methodology, reference cases, and reference scores. http://www.carearthritis.com.
12. Navarro-Compán V, van der Heijde D, Ahmad HA, Miller CG, Wolterbeek R, Landewe R. Measurement error in the assessment of radiographic progression in rheumatoid arthritis (RA) clinical trials: the smallest detectable change (SDC) revisited. Ann Rheum Dis 2013, [Epub ahead of print].
13. Calin A, Garrett S, Whitelock H, Kennedy LG, O'Hea J, Mallorie P, Jenkinson T. A new approach to defining functional ability in ankylosing spondylitis: the development of the bath ankylosing spondylitis functional index. J Rheumatol 1994, 21:2281-2285.
14. Creemers MC, Franssen MJ, van't Hof MA, Gribnau FW, van de Putte LB, van Riel PL. Assessment of outcome in ankylosing spondylitis: an extended radiographic scoring system. Ann rheum dis 2005, 64:127-129. 10.1136/ard.2004.020503, 1755183, 15051621.
15. Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the bath ankylosing spondylitis disease activity index. J Rheumatol 1994, 21:2286-2291.
16. Madsen KB, Jurik AG. Magnetic resonance imaging grading system for active and chronic spondylarthritis changes in the sacroiliac joint. Arthrit Care Res 2010, 62:11-18.
17. Weber U, Pedersen S, Zubler V, Rufibach K, Chan S, Lambert R, Ostergaard M, Maksymowych W. What constitutes the characteristic fat lesion on MRI of the sacroiliac joints in early spondyloarthritis?. J Rheumatol 2013, [Epub ahead of print].